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This area of Mendoza is home to around 900,000 residents.
It sits 17 miles southwest of Jocolí Viejo and about 610 miles west of Buenos Aires, the national capital.
Want to start your adventure with a bang? An iconic sight, Independence Square should't be missed.
Laugh, play and have lots of fun at Termas San Jose, a much-loved destination for travelers of all ages.
You don't need to have fins and scales in order to investigate the marine environments at Municipal Aquarium Mendoza.
Your family will have a blast checking out the rare and exotic animals at the Mendoza Zoo. Be sure to ask at the entrance about zookeeper presentations and where to find the zoo's most popular specimens.
There are few things in life more pleasurable than a delicious wine. Taste some of the region's finest at the Casa Palmero or the Bodega Norton. Afterwards, if you have sufficient time, think about visiting the Clos de los Siete Winery and the Bodegas Chandon.
Whether you're mad about blackjack or you just like the lively atmosphere of casinos, your best bet here is the Regency Casino or the Casino de Uspallata.
Pack a picnic hamper and enjoy some time to yourself in the lush surroundings of General San Martin Park and Mount Aconcagua. O'Higgings Park and La Gloria Mount are two more nice places to while away the day with a good book.
If the sun's out, the sparkling, placid surface of Lake Potrerillos is a fantastic sight.
Switch your phone to silent and give yourself a break from the noise of the modern world at Potrerillos Dam and Cacheuta Thermal Springs. Nature-loving tourists will also have an excellent time at Parque Provincial Aconcagua and Reserva Natural Villavicencio.
The area's exhibition spaces are a treasure trove of interesting facts and stories. The Municipal Museum of Modern Art and the Wine Museum offer a range of collections that are bound to keep you captivated. Another two to consider are the Museo del Area Fundacional and the Juan Cornelio Moyano Natural Sciences and Anthropology Museum.
Mendoza Wine Region's artsy side can be discovered at the Emiliano Guinazu Museum of Fine Arts.
Admire the interesting displays and browse the well-preserved collections at the Pasado Cuyano Museum.
To discover more about the area's rich and colorful past, pay a visit to its many historic structures and monuments. Begin your local history tour at the National University of Cuyo and San Francisco Ruins. More tales from the days of yore await at the Paramillos Mines and Tupungato City Hall.
Whether you consider yourself spiritual or not, you're sure enjoy an afternoon at Basilica de San Francisco and Nuestra Senora de Lourdes Cathedral. If you'd like to explore some more religious sites, check for guided tours at Uspallata Church and Iglesia, Convento y Basílica de San Francisco.
While city squares can at times seem quite similar, each one possesses its own fascinating stories, characters and buildings that make it unique. Wandering through Spain Square or Plaza Italia is always a rewarding experience. San Martin Square and Chile Square also occupy a special place in the locals' hearts.
Investigate the lives and stories of people who helped to make Mendoza Wine Region the place it is today at some of its memorial sites, such as the Monumento al Ejercito Libertador and the Return to the Motherland Monument. If you'd like to continue your trip down memory lane, you should also have a look at the Pasaje San Martin and Edificio Gomez.
Observe the locals out and about while you discover the shops at the area's exciting retail hubs, Central Market and Mendoza Plaza Shopping Center.
The Teatro Independecia and the Gabriela Mistral Theatre are popular theaters that are visited by tourists and local arts lovers alike.
Before you pack your suitcase and head back home, ensure you stop at a few of the lesser-known attractions here. Government House and the Mendoza Tennis Club are two recommended options. If you've got more time to spare, also visit the Club Mendoza de Regatas or the Julio Le Parc Cultural Center.
Mendoza Wine Region is known as a worthwhile destination, with no less than 69 Mendoza Wine Region lodging options to choose from on Expedia.
Be sure to check out the Park Hyatt Mendoza, at Chile 1124, and Sheraton Mendoza Hotel, at Primitivo De La Reta 989. If those don't grab you, why not check out the Hostel Wineries, at Urquiza 2997, Coquimbito, and the Itaka Hostel, at Av. Aristides Villanueva 480, two of the cheaper options in town.
While you're in Mendoza Wine Region of course you will want to visit Independence Square, so another option is to stay in the vicinity of this famed attraction. The Premium Tower is approximately 0.2 miles away. Another alternative is the Paradise Departamentos, which is around 0.5 miles away.
Everyone knows you don't go on a vacation to sit in a small seat on a plane and sleep in a different bed. Vacations are all about the adventures you have while you're away!
Wondering what to do first? Why not think about purchasing a Half-Day Mendoza Wine Country Experiences?
Take a look at our Mendoza Wine Region things to do page for a full list.
Located in Historic Center, this luxury hotel is steps from Teatro Independecia and Independence Square. General San Martin Park is 1.8 mi (2.8 km) away. Belgrano Station is 7 minutes by foot and Mendoza Station is 11 minutes.
Located in Historic Center, this spa hotel is within a 10-minute walk of Plaza Italia and Independence Square. General San Martin Park and Malvinas Argentinas Stadium are also within 3 mi (5 km). Belgrano Station is only a 2-minute walk and Mendoza Station is 7 minutes.
This family-friendly Mendoza hotel is located near the airport, within a 10-minute walk of Avenida San Martin and Independence Square. General San Martin Park and Malvinas Argentinas Stadium are also within 3 mi (5 km). Belgrano Station is 16 minutes by foot and Mendoza Station is 22 minutes.
This family-friendly Mendoza hotel is located in the business district, within a 10-minute walk of San Martin Square and Independence Square. General San Martin Park and Malvinas Argentinas Stadium are also within 3 mi (5 km). Mendoza Station is 12 minutes by foot and Belgrano Station is 15 minutes.
Located in Historic Center, this hotel is within a 10-minute walk of Plaza Italia and Independence Square. General San Martin Park and Malvinas Argentinas Stadium are also within 3 mi (5 km). Belgrano Station is only a 2-minute walk and Mendoza Station is 7 minutes.
Located in Historic Center, this spa hotel is within a 10-minute walk of Avenida San Martin and Independence Square. General San Martin Park and Malvinas Argentinas Stadium are also within 3 mi (5 km). Belgrano Station is 15 minutes by foot and Mendoza Station is 22 minutes.
Situated in the suburbs, this hotel is within 6 mi (10 km) of Nieto Senetiner Winery, Caggiati Hnos Y Cia Winery, and Lagarde Winery. Emiliano Guinazu Museum of Fine Arts (Fader House) and Chacras de Coria Town Square are also within 9 mi (15 km).
This family-friendly Mendoza hotel is located near the airport, within a 5-minute walk of Pasado Cuyano Museum and Independence Square. General San Martin Park and Malvinas Argentinas Stadium are also within 3 mi (5 km). Belgrano Station is only a 5-minute walk and Mendoza Station is 10 minutes.