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Medical Center Area Hotels, Boston

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31 Dec - 1 Jan
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1 Jan - 2 Jan
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2 Jan - 4 Jan
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9 Jan - 11 Jan

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Our top choices for Medical Center Area hotels

Exterior detail
The Inn at Longwood Medical

The Inn at Longwood Medical

The Inn at Longwood Medical
3.5 star property
Medical Center Area
8.4 out of 10, Very good, (1003)
"Nice hotel in a good location. "
United States
Chrisann
The price is AU$397
includes taxes & fees
1 Jan - 2 Jan 2026
The Inn at Longwood Medical
Exterior
Nantasket Beach Resort

Nantasket Beach Resort

Nantasket Beach Resort
3.0 star property
21.1 km from Medical Center Area
8.6 out of 10, Excellent, (1003)
"Staff was delightful and rooms were cute! "
United States
Robert
The price is AU$220
includes taxes & fees
25 Jan - 26 Jan 2026
Nantasket Beach Resort
Exterior
Canopy By Hilton Boston Downtown

Canopy By Hilton Boston Downtown

Canopy By Hilton Boston Downtown
4.0 star property
Government Center, 4.7 km from Medical Center Area
9.6 out of 10, Exceptional, (1006)
"Great place to stay"
United States
Joo Ree
The price is AU$310
includes taxes & fees
11 Jan - 12 Jan 2026
Canopy By Hilton Boston Downtown
Exterior
enVision Hotel Boston Everett

enVision Hotel Boston Everett

enVision Hotel Boston Everett
2.0 star property
8.4 km from Medical Center Area
8.6 out of 10, Excellent, (1001)
"Staff was friendly, hotel was beautiful! Very clean!"
United States
tina
The price is AU$164
includes taxes & fees
2 Jan - 3 Jan 2026
enVision Hotel Boston Everett
Reception
Hotel 1868

Hotel 1868

Hotel 1868
3.5 star property
5.7 km from Medical Center Area
9.4 out of 10, Exceptional, (1001)
"Great stay overall "
United States
Elisabet
The price is AU$197
includes taxes & fees
11 Jan - 12 Jan 2026
Hotel 1868
2 bars/lounges
Concord's Colonial Inn

Concord's Colonial Inn

Concord's Colonial Inn
3.0 star property
24.4 km from Medical Center Area
8.6 out of 10, Excellent, (1002)
"We loved historic inn, and its location in Concord "
United States
Kevin
The price is AU$195
includes taxes & fees
1 Jan - 2 Jan 2026
Concord's Colonial Inn
Front of property – evening/night
Porter Square Hotel

Porter Square Hotel

Porter Square Hotel
3.0 star property
5.8 km from Medical Center Area
9.2 out of 10, Wonderful, (1000)
"Very nice hotel"
United States
Tiffany
The price is AU$197
includes taxes & fees
11 Jan - 12 Jan 2026
Porter Square Hotel
Exterior
Pennyweight Hotel Boston, Curio Collection by Hilton

Pennyweight Hotel Boston, Curio Collection by Hilton

Pennyweight Hotel Boston, Curio Collection by Hilton
4.0 star property
West End, 4.5 km from Medical Center Area
8.2 out of 10, Very good, (1090)
"Enjoyed the stay very much. Great location for our trip."
United States
Nancy
The price is AU$275
includes taxes & fees
4 Jan - 5 Jan 2026
Pennyweight Hotel Boston, Curio Collection by Hilton
Desk, iron/ironing board, free cots/infant beds, rollaway beds
Courtyard by Marriott Boston-Cambridge

Courtyard by Marriott Boston-Cambridge

Courtyard by Marriott Boston-Cambridge
3.5 star property
2.5 km from Medical Center Area
8.8 out of 10, Excellent, (1001)
"Great place if you are travelling for"
United States
Karim
The price is AU$188
includes taxes & fees
4 Jan - 5 Jan 2026
Courtyard by Marriott Boston-Cambridge
Daily full breakfast (USD 17 per person)
Hilton Garden Inn Boston/Waltham

Hilton Garden Inn Boston/Waltham

Hilton Garden Inn Boston/Waltham
3.0 star property
14.2 km from Medical Center Area
8.8 out of 10, Excellent, (1001)
"Great staff. Clean, comfy rooms."
United States
Linda
The price is AU$149
includes taxes & fees
3 Jan - 4 Jan 2026
Hilton Garden Inn Boston/Waltham
Indoor pool
Hampton Inn & Suites Boston/Waltham

Hampton Inn & Suites Boston/Waltham

Hampton Inn & Suites Boston/Waltham
2.5 star property
14.6 km from Medical Center Area
9.4 out of 10, Exceptional, (1598)
"The rooms are very clean, the breakfast are good, the lobby are nice."
United States
Herbert
The price is AU$163
includes taxes & fees
7 Jan - 8 Jan 2026
Hampton Inn & Suites Boston/Waltham
Interior
The Arcadian Hotel

The Arcadian Hotel

The Arcadian Hotel
3.5 star property
1.2 km from Medical Center Area
8.0 out of 10, Very good, (3867)
"Wonderful stay"
United States
Victoria
The price is AU$205
includes taxes & fees
6 Jan - 7 Jan 2026
The Arcadian Hotel
Free daily continental breakfast
Residence Inn by Marriott Boston Downtown / South End

Residence Inn by Marriott Boston Downtown / South End

Residence Inn by Marriott Boston Downtown / South End
3.0 star property
1.9 km from Medical Center Area
8.6 out of 10, Excellent, (1001)
"Super clean and spacious room. Really lovely "
United States
Jia
The price is AU$227
includes taxes & fees
3 Jan - 4 Jan 2026
Residence Inn by Marriott Boston Downtown / South End
View from property
AC Hotel by Marriott Boston Downtown

AC Hotel by Marriott Boston Downtown

AC Hotel by Marriott Boston Downtown
3.5 star property
3.5 km from Medical Center Area
8.8 out of 10, Excellent, (1001)
"Spotless, beautiful modern furniture, great mattress "
United States
Afroditi
The price is AU$242
includes taxes & fees
4 Jan - 5 Jan 2026
AC Hotel by Marriott Boston Downtown
Free daily buffet breakfast
HYATT house Boston/Waltham

HYATT house Boston/Waltham

HYATT house Boston/Waltham
3.0 star property
14.1 km from Medical Center Area
8.8 out of 10, Excellent, (1081)
"This place was so amazing! Best staff, clean rooms! Great breakfast! Nice guest and great location!"
United States
Renell Alicia
The price is AU$163
includes taxes & fees
9 Jan - 10 Jan 2026
HYATT house Boston/Waltham
Exterior
Holiday Inn Express Boston - Waltham by IHG

Holiday Inn Express Boston - Waltham by IHG

Holiday Inn Express Boston - Waltham by IHG
2.5 star property
14.4 km from Medical Center Area
9.0 out of 10, Wonderful, (1002)
"Staff was AMAZING! "
United States
Jessica
The price is AU$140
includes taxes & fees
4 Jan - 5 Jan 2026
Holiday Inn Express Boston - Waltham by IHG
View from property
Sheraton Boston Needham Hotel

Sheraton Boston Needham Hotel

Sheraton Boston Needham Hotel
3.5 star property
10.3 km from Medical Center Area
8.8 out of 10, Excellent, (1530)
"Great experience amazing food"
United States
David
The price is AU$183
includes taxes & fees
8 Jan - 9 Jan 2026
Sheraton Boston Needham Hotel
Front of property – evening/night
Sonesta Simply Suites Boston Burlington

Sonesta Simply Suites Boston Burlington

Sonesta Simply Suites Boston Burlington
2.0 star property
19 km from Medical Center Area
9.0 out of 10, Wonderful, (150)
"Nice room good staff "
United States
scott
The price is AU$158
includes taxes & fees
7 Jan - 8 Jan 2026
Sonesta Simply Suites Boston Burlington
Exterior
Courtyard by Marriott Boston Downtown/North Station

Courtyard by Marriott Boston Downtown/North Station

Courtyard by Marriott Boston Downtown/North Station
3.0 star property
West End, 4.7 km from Medical Center Area
9.4 out of 10, Exceptional, (1209)
"Fantastic and we were allowed early check in Great location!!"
United States
Ryan
The price is AU$233
includes taxes & fees
4 Jan - 5 Jan 2026
Courtyard by Marriott Boston Downtown/North Station
Italian cuisine
Cambria Hotel Boston Somerville

Cambria Hotel Boston Somerville

Cambria Hotel Boston Somerville
3.0 star property
5 km from Medical Center Area
9.6 out of 10, Exceptional, (1004)
"Great room, wonderful staff, convenient "
United States
Sarah
The price is AU$227
includes taxes & fees
25 Jan - 26 Jan 2026
Cambria Hotel Boston Somerville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Our guide on where to stay in Medical Center Area

Find the best Medical Center Area areas for the activities you enjoy most.
Downtown Boston showing a city and night scenes as well as a small group of people

Downtown Boston

This is Boston’s business district, now and back when the city was just starting.

Seaport District featuring a city, a high-rise building and a river or creek

Seaport District

Once known as strong working-class neighbourhood, South Boston has turned into a haven for young professionals.

Back Bay showing heritage architecture, a city and street scenes

Back Bay

Head to Back Bay for Victorian brownstone homes, hip coffee joints and a shopping district that rivals Manhattan’s 5th Avenue.

Beacon Hill which includes landscape views

Beacon Hill

Take a walk through the charming streets, historic buildings and small-town atmosphere of Boston’s oldest and wealthiest suburbs.

North End

The ample dining options and captivating waterfront views are just a few popular features of the neighbourhood. Make a stop by New England Aquarium or Old North Church while you're visiting, and jump aboard the metro at Aquarium to get around town.

Top Medical Center Area Hotel Reviews

Hilton Boston Logan Airport

Hilton Boston Logan Airport

10/10 Excellent
"Clean quiet shuttle"
Tina 1-night trip
Posted 1 day ago
Hilton Boston Logan Airport

Frequently asked questions

What's it like in Medical Center Area?
Guests are sure to enjoy their time checking out all that Boston's Medical Center Area neighbourhood has to offer. Make sure that you visit Isabella Stewart Gardner Museum and Warren Anatomical Museum as part of your Medical Center Area travel plans.
What's the best accommodation in Medical Center Area?
Based on Expedia customer reviews, The Inn at Longwood Medical is the highest ranked property in Medical Center Area. This hotel is a short 1-minute walk from Children's Hospital Boston, and it offers a restaurant and a fitness centre.
How many hotels will I be able to find in Medical Center Area?
When you want to put your feet up after a day of exploring the sights in Boston, you can choose from 17 Expedia hotels and other accommodation options in Medical Center Area.
If I need to cancel my hotel reservation in Medical Center Area, will I receive a refund?
Yes! Most hotel reservations are refundable provided that you cancel before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you booked a non-refundable reservation, you may still be able to cancel and be given a refund within a 24-hour period of booking. Add dates, click "Search", then you can use the "fully refundable" filter to view the best deals in Medical Center Area.
What can I see and do in this Boston neighbourhood?
Sights like Isabella Stewart Gardner Museum and Warren Anatomical Museum can be part of your cultural tour of Medical Center Area. When you're sightseeing in Boston, Fenway Park and TD Garden are also worth a stop.
How can I get around Medical Center Area and the greater Boston area?
If you want to see more of the city, Longwood Medical Area Station is the closest metro stop. Others nearby include Brigham Circle Station and Museum of Fine Arts Station.