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Medical Center Area Hotels, Boston

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Our top choices for Medical Center Area hotels

1. The Inn at Longwood Medical

The Inn at Longwood Medical
3.5 star property
Medical Center Area
8.4 out of 10, Very good, (1,007 reviews)
"So convenient to hospitals!"
United States
Kara
The price is AU$491
includes taxes & fees
6 Aug - 7 Aug
The Inn at Longwood Medical

2. The Verb Hotel

The Verb Hotel
3.5 star property
0.9 km from Medical Center Area
9.6 out of 10, Exceptional, (2,089 reviews)
"Great stay for a Red Sox game!"
United States
Casie
The price is AU$376
includes taxes & fees
12 Aug - 13 Aug
The Verb Hotel

3. Arcadian Hotel

Arcadian Hotel
3.5 star property
1.2 km from Medical Center Area
8.0 out of 10, Very good, (4,334 reviews)
"Great hotel and location"
United Kingdom
Carl
The price is AU$312
includes taxes & fees
17 Aug - 18 Aug
Arcadian Hotel

4. The Midtown Hotel MOD Collection by Sonesta

The Midtown Hotel MOD Collection by Sonesta
3.0 star property
Prudential - St. Botolph, 1.8 km from Medical Center Area
8.2 out of 10, Very good, (678 reviews)
"Great location and comfortable room with friendly and accommodating staff."
United States
Allen
The price is AU$299
includes taxes & fees
9 Aug - 10 Aug
The Midtown Hotel MOD Collection by Sonesta

5. citizenM Boston Back Bay

citizenM Boston Back Bay
4.0 star property
1.6 km from Medical Center Area
9.4 out of 10, Exceptional, (2,927 reviews)
"Friendly staff, clean room and great location."
United States
Yanira
The price is AU$332
includes taxes & fees
9 Aug - 10 Aug
citizenM Boston Back Bay

6. Hyatt Regency Boston/Cambridge

Hyatt Regency Boston/Cambridge
4.0 star property
1.7 km from Medical Center Area
9.0 out of 10, Wonderful, (2,480 reviews)
"Great place to stay"
United States
Zac
The price is AU$310
includes taxes & fees
16 Aug - 17 Aug
Hyatt Regency Boston/Cambridge

7. Hampton Inn & Suites Boston Crosstown Center

Hampton Inn & Suites Boston Crosstown Center
3.0 star property
2.6 km from Medical Center Area
8.0 out of 10, Very good, (1,755 reviews)
"Staff was amazing, breakfast was good, Rooms were very clean and tidy."
United States
Hope
The price is AU$282
includes taxes & fees
10 Aug - 11 Aug
Hampton Inn & Suites Boston Crosstown Center

8. Residence Inn by Marriott Boston Downtown / South End

Residence Inn by Marriott Boston Downtown / South End
3.0 star property
1.9 km from Medical Center Area
8.8 out of 10, Excellent, (1,003 reviews)
"Our stay was very nice Rooms very big with amenities and breakfast was very tasty"
United States
Ewa B
The price is AU$306
includes taxes & fees
9 Aug - 10 Aug
Residence Inn by Marriott Boston Downtown / South End

9. Hotel Commonwealth

Hotel Commonwealth
4.5 star property
Fenway–Kenmore, 1.3 km from Medical Center Area
9.4 out of 10, Exceptional, (2,217 reviews)
"Spacious and clean rooms, super friendly staff"
United States
Hiba
The price is AU$514
includes taxes & fees
9 Aug - 10 Aug
Hotel Commonwealth

10. Sheraton Boston, a Marriott Hotel

Sheraton Boston, a Marriott Hotel
4.0 star property
Prudential - St. Botolph, 1.8 km from Medical Center Area
8.6 out of 10, Excellent, (1,863 reviews)
"Great stay"
United States
Howard
The price is AU$399
includes taxes & fees
9 Aug - 10 Aug
Sheraton Boston, a Marriott Hotel

11. Copley Square Hotel, a FOUND Hotel

Copley Square Hotel, a FOUND Hotel
4.0 star property
Prudential - St. Botolph, 2.3 km from Medical Center Area
8.6 out of 10, Excellent, (4,032 reviews)
"Enjoyed my stay!!"
United States
Lorenzo Enrique
The price is AU$257
includes taxes & fees
9 Aug - 10 Aug
Copley Square Hotel, a FOUND Hotel

12. Oasis Guest House

Oasis Guest House
2.5 star property
Fenway–Kenmore, 1.5 km from Medical Center Area
9.4 out of 10, Exceptional, (1,471 reviews)
"great location."
United States
Jingjing
The price is AU$297
includes taxes & fees
16 Aug - 17 Aug
Oasis Guest House

13. Copley House

Copley House
3.0 star property
Prudential - St. Botolph, 2 km from Medical Center Area
9.2 out of 10, Wonderful, (2,213 reviews)
"Wonderful place in a great location!"
United States
David
The price is AU$275
includes taxes & fees
16 Aug - 17 Aug
Copley House

14. The Westin Boston Seaport District

The Westin Boston Seaport District
4.0 star property
Seaport District, 5 km from Medical Center Area
9.2 out of 10, Wonderful, (2,391 reviews)
"Great stay!!"
United States
Patrick
The price is AU$783
includes taxes & fees
25 Aug - 26 Aug
The Westin Boston Seaport District

15. Hilton Boston Back Bay

Hilton Boston Back Bay
4.0 star property
Fenway–Kenmore, 1.8 km from Medical Center Area
8.6 out of 10, Excellent, (85 reviews)
"Our stay was wonderful. The room was clean and the staff was friendly."
United States
Robert W.
The price is AU$446
includes taxes & fees
16 Aug - 17 Aug
Hilton Boston Back Bay

16. Aloft by Marriott Boston Seaport District

Aloft by Marriott Boston Seaport District
3.0 star property
Seaport District, 4.9 km from Medical Center Area
8.8 out of 10, Excellent, (1,472 reviews)
"The hotel was great. Staff were very helpful. Hotel was very functional. One of the best hotels we have stayed in."
United States
Jeremy
The price is AU$302
includes taxes & fees
9 Aug - 10 Aug
Aloft by Marriott Boston Seaport District

17. Boston Marriott Copley Place

Boston Marriott Copley Place
4.0 star property
Prudential - St. Botolph, 2.2 km from Medical Center Area
9.2 out of 10, Wonderful, (1,840 reviews)
"Great hotel to visit Boston!"
United States
roberto
The price is AU$497
includes taxes & fees
23 Aug - 24 Aug
Boston Marriott Copley Place

18. Staypineapple, A Delightful Hotel, South End

Staypineapple, A Delightful Hotel, South End
3.0 star property
Columbus, 2.9 km from Medical Center Area
9.0 out of 10, Wonderful, (1,009 reviews)
"Cute litlle place to stay!"
United States
Christopher
The price is AU$246
includes taxes & fees
24 Aug - 25 Aug
Staypineapple, A Delightful Hotel, South End

19. Hampton by Hilton at the Boston Seaport District

Hampton by Hilton at the Boston Seaport District
3.0 star property
Seaport District, 5.4 km from Medical Center Area
9.2 out of 10, Wonderful, (2,861 reviews)
"We did enjoy our stay there, very nice and helpful staff, very clean place and the location was great."
Canada
Brahm
The price is AU$313
includes taxes & fees
9 Aug - 10 Aug
Hampton by Hilton at the Boston Seaport District

20. Hilton Boston Park Plaza

Hilton Boston Park Plaza
4.0 star property
Bay Village, 3.1 km from Medical Center Area
8.4 out of 10, Very good, (3,079 reviews)
"Great stay"
United States
Roberto I Santeliz
The price is AU$344
includes taxes & fees
2 Aug - 3 Aug
Hilton Boston Park Plaza
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Our guide on where to stay in Medical Center Area

Find the best Medical Center Area areas for the activities you enjoy most.

Downtown Boston

This is Boston’s business district, now and back when the city was just starting.

Back Bay

Head to Back Bay for Victorian brownstone homes, hip coffee joints and a shopping district that rivals Manhattan’s 5th Avenue.

Seaport District

Once known as strong working-class neighbourhood, South Boston has turned into a haven for young professionals.

Beacon Hill

Take a walk through the charming streets, historic buildings and small-town atmosphere of Boston’s oldest and wealthiest suburbs.

North End

The ample dining options and captivating waterfront views are just a few popular features of the neighbourhood. Make a stop by Boston Harbor or New England Aquarium while you're visiting, and jump aboard the metro at Aquarium to get around town.

Top Medical Center Area Hotel Reviews

Recent Reviews in Medical Center Area

Frequently asked questions

What are the best hotels in Medical Center Area that travellers recommend?
For highly recommended hotels in the Medical Centre Area, consider The Eliot Hotel, Raffles Boston, The Colonnade Hotel Back Bay, Iris Hotel Boston, and Mandarin Oriental, Boston.

The 4-star The Eliot Hotel, with an impressive 9.6 rating, is frequently praised for its spacious, clean rooms and friendly, helpful staff. Guests appreciate the beautiful suites and excellent service. It is located near The Fens and the Isabella Stewart Gardner Museum.

Raffles Boston, a 5-star hotel rated 9.6, offers exceptional service and attentive staff. Guests enjoy the nice rooms, and its convenient location is a highlight, being just 0.1 km from 200 Clarendon Street. It also features deep soaking bathtubs and rainfall showerheads.

Another excellent choice is The Colonnade Hotel Back Bay, a 4-star hotel with a 9.2 rating. This hotel is commended for its excellent location, friendly staff, and spacious, clean rooms. It also offers convenient parking and great service. The hotel is close to the Minuteman Bikeway.

The 4-star Iris Hotel Boston, rated 9.4, is known for its comfortable, great rooms and excellent amenities. The staff are friendly and helpful, and guests consistently highlight the fantastic service. It is conveniently located near the Brookline Farmers Market.

Finally, the 5-star Mandarin Oriental, Boston, with a 9.4 rating, receives high praise for its amazing staff who are always willing to help. Guests appreciate the perfect, clean rooms and the excellent location. It is situated close to 200 Clarendon Street and The Fens.
What are the best family hotels in Medical Center Area?
For families visiting the Medical Centre Area, several excellent hotels offer amenities and features to ensure a comfortable stay, including Raffles Boston, The Lenox Hotel Boston, Residence Inn by Marriott Boston Back Bay/Fenway, and Four Seasons Hotel One Dalton Street, Boston.

Raffles Boston is a 5-star hotel with an outstanding 9.6 rating. This hotel provides connecting rooms, books and games for children, kids' meals, children's bathrobes, complimentary cribs, and onsite babysitting services. Guests frequently praise the attentive staff, nice rooms, and convenient location, with Innovation District just 2.9 km away and Gibson House Museum 0.7 km away.

Another highly-rated option is The Lenox Hotel Boston, a 4.5-star hotel with a 9.6 rating. It offers complimentary cribs, kids' meals in the restaurant, onsite babysitting, connecting rooms, and rollaway extra beds. The hotel also features a child-friendly window design for added peace of mind. Customers appreciate the friendly and helpful staff, excellent location, and clean rooms.

The 3-star Residence Inn by Marriott Boston Back Bay/Fenway, rated 9.2, is a great choice for families. It provides complimentary rollaway extra beds and cribs, sofa beds, connecting rooms, and a pool. It's conveniently located near The Fens, just 0.3 km away, and the Isabella Stewart Gardner Museum, 0.8 km away. Guests frequently mention the clean rooms, friendly staff, and great breakfast.

The 5-star Four Seasons Hotel One Dalton Street, Boston, with a 9.6 rating, is another excellent family-friendly option. It offers complimentary rollaway extra beds and cribs, connecting rooms, a pool, sofa beds, and kids' meals in the restaurant. The hotel is praised for its exceptional staff, great location, and clean rooms. It is 1.5 km from The Fens and 1.3 km from Gibson House Museum.
What are the best 5-star hotels in Medical Center Area?
For exceptional 5-star accommodation in the Medical Centre Area, consider the Raffles Boston, Mandarin Oriental, Boston, and the Four Seasons Hotel One Dalton Street, Boston.

The 5-star Raffles Boston, with an outstanding 9.6 rating, offers luxurious features such as deep soaking bathtubs, rainfall showerheads, and designer toiletries. Guests frequently praise the attentive staff and great rooms. The hotel also provides 24-hour room service and valet parking, and is conveniently located near 200 Clarendon Street, just 0.1 km away.

Another excellent choice is the 5-star Mandarin Oriental, Boston, rated 9.4. This hotel boasts Frette Italian sheets and premium bedding for a truly comfortable stay, along with 24-hour room service and valet parking. Guests consistently praise the amazing staff and excellent location, with 200 Clarendon Street just 0.6 km away.

The 5-star Four Seasons Hotel One Dalton Street, Boston, also with a 9.6 rating, offers a refined experience. It features deep soaking bathtubs, designer toiletries, and premium bedding. The hotel also provides 24-hour room service and valet parking. Travellers regularly highlight the exceptional staff, great facilities, and clean rooms. It is also conveniently located near 200 Clarendon Street, 0.9 km away.
What are the best spa hotels in Medical Center Area?
For an exceptional spa experience in the Medical Centre Area, consider the Mandarin Oriental, Boston, Raffles Boston, Four Seasons Hotel One Dalton Street, Boston, or the Iris Hotel Boston.

The 5-star Mandarin Oriental, Boston, with an impressive 9.4 rating, offers an extensive spa experience including deep tissue, hot stone, and Swedish massages, hydrotherapy treatments, and a steam room. Guests consistently praise the amazing and always willing to help staff, the excellent location, and the perfect, clean rooms. It is conveniently located near 200 Clarendon Street and the Christian Science Plaza.

Another outstanding option is the 5-star Raffles Boston, boasting an excellent 9.6 rating. This hotel provides a full-service spa with a hot tub, steam room, and dedicated treatment rooms for massages and body treatments. Reviewers frequently highlight the attentive staff, nice rooms, and convenient location, being very close to 200 Clarendon Street and Gallery Naga.

The 5-star Four Seasons Hotel One Dalton Street, Boston, also with a 9.6 rating, features a full-service spa offering body wraps, scrubs, manicures, pedicures, and a steam room. Guests consistently praise the exceptional staff, great location, and clean rooms. It's ideally situated near the Christian Science Plaza and Prudential Tower.

For a highly-rated 4-star option, the Iris Hotel Boston, with a 9.4 rating, provides a range of spa services including deep tissue and hot stone massages, aromatherapy, and facial treatments. Travellers appreciate the friendly and helpful staff, comfortable rooms, and excellent location, being close to the John Fitzgerald Kennedy National Historic Site.
What are the top boutique hotels in Medical Center Area?
For a top boutique hotel in the Medical Centre Area, The Westin Copley Place, Boston, a Marriott Hotel is an excellent choice.

This 4-star hotel, with a 9.2 rating, is known for its Art Deco design and offers premium bedding for a comfortable stay. Guests often highlight the convenient location and the friendly, helpful staff. The hotel provides excellent fitness facilities, including a 24-hour fitness centre and on-site yoga and fitness classes. It is also very close to 200 Clarendon Street, just 0.2 km away, and the Prudential Tower, 0.4 km away.
What are the most romantic hotels in Medical Center Area for couples?
For a romantic stay in the Medical Centre Area, several highly-rated hotels offer exceptional experiences for couples, including The Eliot Hotel, Four Seasons Hotel One Dalton Street, Boston, Raffles Boston, and Iris Hotel Boston.

The 4-star Eliot Hotel, with a superb 9.6 rating, is a wonderful choice for couples. It features elegant suites, premium bedding, and designer toiletries. Guests frequently praise the excellent staff and spacious, clean rooms. Dining options for couples are available, and the hotel provides valet parking. It is also conveniently located near the Prudential Tower, just 0.5 km away, and the Christian Science Plaza, 0.6 km away.

Another outstanding option is the 5-star Four Seasons Hotel One Dalton Street, Boston, which also boasts a 9.6 rating. This hotel is situated in a shopping district and offers luxurious amenities such as deep soaking bathtubs, designer toiletries, and 24-hour room service. Couples can enjoy treatment rooms, and guests consistently praise the exceptional staff and facilities. The hotel is very close to the Prudential Tower, only 0.2 km away, and the Christian Science Plaza, 0.3 km away.

The 5-star Raffles Boston, rated 9.6, provides a truly luxurious and romantic experience. It features deep soaking bathtubs, rainfall showerheads, designer toiletries, and fireplaces. Couples can indulge in spa amenities like a hot tub, sauna, and couples treatment rooms. Guests frequently highlight the attentive staff and convenient location. It is just 0.1 km from 200 Clarendon Street and 0.6 km from the Prudential Tower.

Finally, the 4-star Iris Hotel Boston, with a 9.4 rating, is another excellent choice for couples. This hotel offers premium bedding, Frette Italian sheets, champagne service, and private indoor hot tubs for a truly intimate experience. Guests appreciate the friendly and helpful staff, comfortable rooms, and excellent location. It is located 0.7 km from the John Fitzgerald Kennedy National Historic Site.
When is the best time to go to Medical Center Area?
The best time to visit the Medical Center Area is during the late spring (May to June) or early autumn (September to October).

These periods offer pleasant weather, with moderate temperatures and less humidity than the peak summer months. You'll find it comfortable for walking around and exploring the area's amenities. Additionally, these shoulder seasons generally mean fewer crowds compared to the busiest summer travel period, leading to a more relaxed experience.

For those visiting for medical appointments, these months also generally provide a calmer environment around the hospitals and clinics.
Can I cancel my hotel reservation on Expedia?
Many Expedia hotel reservations are refundable, provided that you cancel before the hotel's cancellation deadline − this is often within 24 to 48 hours of your scheduled arrival. If you have a non-refundable booking, it might still be possible to receive a refund if you cancel it within 24 hours of booking. Be sure to check your booking confirmation for the exact cancellation policy. For maximum flexibility, use our 'Fully refundable property' filter during your search to find the right Medical Center Area hotel for you.
How can I save on a hotel booking in Medical Center Area with Expedia?
One Key™—Expedia's free travel rewards program—gives you instant access to discounts with Member Prices on Medical Center Area hotels. Plus, you'll earn OneKeyCash™* on eligible bookings to use on future trips. Booking an Expedia hotel and flight package is another great way to save, where bundling can result in significant savings. *Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
How much is the nightly rate for a hotel in Medical Center Area?
Hotel prices in Medical Center Area often vary, but you can find a great deal on Expedia. Different factors affect nightly hotel rates, such as the time of year or the days of the week you want to book. To find the best deals for your stay, be flexible with your dates and sort search results by 'Price: low to high' for our cheapest rates.