Mayo Clinic Holidays

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Our guide on where to stay in Mayo Clinic

Find the best Mayo Clinic areas and neighborhoods for the activities you enjoy most. Learn more about Mayo Clinic
Downtown Phoenix showing signage and night scenes

Downtown Phoenix

3 out of top 10 points of interest in this area
4/5(14 area reviews)

Cheer on the Phoenix Suns at an NBA game or walk around the city’s historic precinct as you explore the state capital.

Find hotels in Downtown Phoenix

Our pick of the best Mayo Clinic Hotel Deals

FOUNDRE Phoenix

FOUNDRE Phoenix

4 out of 5
1100 N Central Avenue, Phoenix, AZ
Fully refundableReserve now, pay when you stay
9/10 Wonderful! (2,075 reviews)
"The front desk was very helpful at checking. Room service from the restaurant was wonderfully accommodating."

Reviewed on 25 Sept 2025

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FOUNDRE Phoenix
Talking Stick Resort

Talking Stick Resort

4 out of 5
9800 E. Talking Stick Way, Scottsdale, AZ
9.2/10 Wonderful! (3,887 reviews)
"loved it"

Reviewed on 25 Sept 2025

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Talking Stick Resort
Arizona Grand Resort & Spa

Arizona Grand Resort & Spa

4 out of 5
8000 S. Arizona Grand Parkway, Phoenix, AZ
Fully refundableReserve now, pay when you stay
The price is AU$342 per night from 28 Sept to 29 Sept
AU$342
28 Sept - 29 Sept
includes taxes & fees
8.4/10 Very Good! (2,199 reviews)
"They had golf carts to help you get a round to local businesses. Park was slim picking the resort was very busy and they sale day passes to there water wish it was hotel guests only. Or later or before hour for guests. Room was big."

Reviewed on 21 Sept 2025

Arizona Grand Resort & Spa
See all 12,942 properties in Mayo Clinic
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Holidays
All Inclusive Holidays
All Inclusive Holidays
Cheap Holidays
Cheap Holidays
Cheap Holidays
beach holidays
Beach Holidays
Beach Holidays

Frequently asked questions

How much does a Mayo Clinic holiday package cost?
Starting from as low as , a package is your gateway to low-priced travel. Customize your Mayo Clinic trip by choosing from our extensive range of hotels, flights and rental cars.
How do I get a cheap travel package to Mayo Clinic?
Our Mayo Clinic holiday packages promise plenty of savings for the savvy globetrotter. For the best deals, simply combine your flights, hotels and activities into an affordable package. But low prices are just the beginning of your next unforgettable adventure. Book with Expedia and and you'll have over 550 airlines and 1 000 000 properties throughout the world to pick from. No matter your budget or style, there's a holiday package that's perfect for you.
Where should I stay in Mayo Clinic?
Cross Tournament Players Club of Scottsdale off your must-see list and then stay right near it. Soak up the exciting vibe around this terrific attraction and drop by whenever the mood strikes!
What are the top hotels in Mayo Clinic?
Whether you plan to stay for a night or a week in Mayo Clinic, you'll get a great night's rest at Sonesta Select Scottsdale at Mayo Clinic Campus. This option is popular with plenty of travellers.
How far in advance should I book my Mayo Clinic holiday?
Search Expedia to compare international flights as early as possible. In most cases, you can purchase a seat up to 12 months prior to departure. If it's too early for your preferred carrier, or you have to book last minute, don't despair. Cheap fares to Mayo Clinic sometimes occur within weeks of departure.
What does an Expedia Mayo Clinic travel package include?
It all depends on what sort of trip you have in the works. Mayo Clinic holiday deals can include car rentals, hotels and flights. You can mix and match to find the travel package that suits your style and budget. You can also add on activities and experiences after you've booked to score even bigger discounts.
What should I know before booking a Mayo Clinic travel package?
When you book your flights, hotels and car rentals together, you'll walk away with awesome discounts. Whether you're planning a beach break in a villa or want to stay in a fancy hotel in the city, Expedia will help make it happen.
Can I choose my airline with a Mayo Clinic Expedia holiday package?
You can, and with over 550 airlines to choose from all over the world, you've got lots of choice. Take a look at the available options and find out which airline fits your budget and needs.
If I'm not able to travel, can I cancel my Mayo Clinic holiday package?
You sure can, and we'll help you every step of the way. You may be able to cancel and rebook your Mayo Clinic holiday package at no cost if you booked in the last 24 hours. But you may incur a fee from your hotel, airline or car rental company if you booked more than 24 hours ago. If your travel plans suddenly change, have a look at our Customer Service Portal for further information.

Discover the most popular places to visit in Mayo Clinic

Phoenix Convention Center

Phoenix Convention Center

During your trip, find out what's happening in Phoenix Convention Center, a top convention centre in Phoenix. Experience the fascinating museums and acclaimed theatre scene in this vibrant area.

Phoenix Convention Center
Westgate Entertainment District

Westgate Entertainment District

You can browse for the perfect souvenirs at Westgate Entertainment District during your stay in Glendale. Experience the area's great live music or attend a sporting event.

Westgate Entertainment District
Desert Diamond Arena

Desert Diamond Arena

Catch an event at Desert Diamond Arena during your trip to Glendale. Experience the area's great live music and lively festivals.

Desert Diamond Arena

Activities

Phoenix: Self-Drive ATV/UTV Rental in the Sonoran Desert

Phoenix: Self-Drive ATV/UTV Rental in the Sonoran Desert

AU$309
per traveller
100% of travellers recommend
Phoenix: Self-Drive ATV/UTV Rental in the Sonoran Desert
Phoenix Zoo Admission Ticket

Phoenix Zoo Admission Ticket

AU$60
per adult
86% of travellers recommend
Phoenix Zoo Admission Ticket
Let's Fly!

Sunrise Hot Air Balloon Ride in Phoenix with Breakfast

AU$301
per adult
100% of travellers recommend
Sunrise Hot Air Balloon Ride in Phoenix with Breakfast
See all activities in Phoenix
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.