10 Best Hotels & Accommodation Closest to Mayo Clinic in Rochester from AU$109

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Our top choices for Mayo Clinic hotels

An outdoor seating area with wooden pillars, colorful striped cushions, and potted plants.

A modern restaurant with a counter, seating area, and a TV screen.

A modern lounge area with a sofa, chairs, and tables.

A modern hotel room with a bed, desk, and kitchenette.

1. Home2 Suites by Hilton Rochester Mayo Clinic Area

2.6 km from Mayo Clinic

howard

AU$209

includes taxes & fees

24 Oct - 25 Oct

A spacious living area with a modern staircase, leather sofas, and contemporary lighting.

An outdoor seating area with blue sofas and wicker chairs, a wooden table, and green ottomans on a tiled patio.

A modern pool table in a spacious, well-lit room with large windows and a bar area.

A modern interior with a large dining table, sofas, and a kitchen area.

2. The Berkman

Folwell, 1.4 km from Mayo Clinic

Suzette

AU$249

includes taxes & fees

4 Nov - 5 Nov

A modern living room with a flat-screen TV, a fireplace, comfortable seating, and a large window with a city view.

A modern indoor swimming pool with seating areas and a city view.

A modern hotel entrance with a glass facade, illuminated signage, and a covered walkway.

A spacious lobby with modern furniture, a spiral staircase, and large windows offering views of the outdoors.

3. Hilton Rochester Mayo Clinic Area

Downtown Rochester, 0.3 km from Mayo Clinic

Raymond

AU$296

includes taxes & fees

17 Oct - 18 Oct

An outdoor patio area with a concrete floor, wooden fence, and string lights.

A modern living room with a stone fireplace, a blue armchair, a round coffee table, and a large window offering a view of the outdoors.

A Fairfield Inn & Suites hotel with a modern design, featuring a prominent entrance and a parking area.

4. Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys

Kutzky Park, 1.8 km from Mayo Clinic

Jon

AU$185

includes taxes & fees

17 Oct - 18 Oct

A coffee shop interior with a wooden counter, menu boards, and seating area.

A hotel room with a bed, bedside table, and a window with curtains.

An outdoor seating area with tables and chairs, a neon sign, and flower arrangements.

5. TownePlace Suites by Marriott Rochester Mayo Clinic Area

Kutzky Park, 0.4 km from Mayo Clinic

Hafsa

AU$226

includes taxes & fees

23 Oct - 24 Oct

A swimming pool with clear blue water, surrounded by lounge chairs and a view of residential buildings through large windows.

A modern reception area with a brick-patterned wall, two reception desks, a flat-screen TV, and seating arrangements including a sofa and chairs.

A modern hotel with a flat roof, multiple windows, and a covered outdoor seating area.

A modern lounge area with seating, a fireplace, and a bar area.

6. Residence Inn by Marriott Rochester Mayo Clinic Area South

2.4 km from Mayo Clinic

Chee

AU$218

includes taxes & fees

17 Oct - 18 Oct

A modern indoor patio with a fire feature, seating, and large windows.

A modern living room with a fireplace, large windows, and a flat-screen TV mounted on the wall.

A modern hotel lobby with a large glass wall, a green wall mural, and a seating area with sofas and chairs.

A reception area with a curved reception desk, wooden shelving, and a green moss wall with the text "I ♥ EVEN".

7. EVEN Hotel Rochester - Mayo Clinic Area by IHG

Kutzky Park, 1 km from Mayo Clinic

Rici

AU$215

includes taxes & fees

6 Nov - 7 Nov

A modern outdoor seating area with a built-in fireplace, two wooden chairs, a table, and a sofa.

A modern kitchen with a central island, bar stools, and pendant lighting. A living area with a sofa, ottoman, and a view of the outdoors is visible.

A gym with various exercise equipment, including treadmills, stationary bikes, and weight machines.

A hotel room with a kitchenette, a bed, a sofa, a small table, and a window with curtains.

8. Staybridge Suites Rochester - Mayo Clinic Area by IHG

Kutzky Park, 1 km from Mayo Clinic

Sheri

AU$191

includes taxes & fees

18 Oct - 19 Oct

A bedroom with a large bed, a TV on a dresser, and a view of the city through large windows.

A modern kitchen with wooden cabinets, a granite countertop, and a stainless steel stove.

An indoor swimming pool with a clock on the wall, lounge chairs, and a lifeguard warning sign.

9. Broadway Plaza, Trademark Collection by Wyndham

Downtown Rochester, 0.3 km from Mayo Clinic

Danny

AU$279

includes taxes & fees

24 Oct - 25 Oct

A Courtyard Marriott hotel with multiple floors, a brick facade, and illuminated signage.

A modern living room with a sofa, a round coffee table, and a side table. There are large windows with a view of the outside.

A hotel room with a bed, a sofa, a desk, a TV, and a wall art piece.

A conference room with a long table, multiple chairs, and decorative wall art.

10. Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys

Kutzky Park, 1.4 km from Mayo Clinic

MATTHEW

AU$186

includes taxes & fees

6 Nov - 7 Nov

An outdoor patio with a brick floor, stone fireplace, and wooden pergola.

An indoor swimming pool with clear pool rules posted on the wall, a lifeguard chair, and a pool lift sign.

A modern hotel lobby with a stone wall fireplace, comfortable seating, and a chandelier.

A gym with exercise equipment, a clock, and a window with blinds.

11. Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys

Kutzky Park, 1.4 km from Mayo Clinic

Lin

AU$195

includes taxes & fees

6 Nov - 7 Nov

An outdoor seating area with a fire feature, blue cushioned chairs, and a modern building with large windows in the background.

A modern Hyatt House hotel with a prominent 'Hyatt House' sign, multiple floors, and a parking garage.

A modern dining area with round tables and chairs, a large painting on the wall, and a flat-screen TV mounted above a geometric-patterned wall.

A modern indoor pool area with lounge chairs and a pool.

12. Hyatt House Rochester/Mayo Clinic Area

Downtown Rochester, 0.5 km from Mayo Clinic

Lucy

AU$195

includes taxes & fees

17 Oct - 18 Oct

A modern kitchen with a dark countertop, black cabinets, a microwave, and a refrigerator. There are two pendant lights above the counter.

A hotel room with a large round table, two sofas, a TV, and a bed.

A hotel lobby with a reception desk, seating area, and a large window.

A hotel gym with treadmills, elliptical machines, and free weights.

13. Candlewood Suites Rochester Mayo Clinic Area by IHG

2.6 km from Mayo Clinic

Sean

AU$191

includes taxes & fees

11 Oct - 12 Oct

A self-service breakfast station with a waffle maker, coffee machines, and a variety of condiments.

A compact laundry area with a washing machine, dryer, and a water fountain.

A reception area with a wooden reception desk, a red doormat, and framed awards on the wall.

A hotel lobby with leather sofas, a stone fireplace, and a patterned carpet.

14. Econo Lodge Mayo Clinic Area

3.1 km from Mayo Clinic

Ashley

AU$109

includes taxes & fees

1 Nov - 2 Nov

A reception area with a wooden reception desk, a "Welcome to the Bread & Butter State" sign, and a "Please Center" sign.

A coffee station with four coffee dispensers, a stack of disposable cups, and a tray with various coffee-related items.

A pool area with a table and chairs, a lifeguard chair, and a pool lift.

A hotel room with a bed, a desk, a chair, a TV, and a bathroom visible through an open door.

15. Hampton Inn Rochester-South

2.9 km from Mayo Clinic

dennis

AU$174

includes taxes & fees

1 Nov - 2 Nov

A room with a fireplace, two leather armchairs, a sofa, and a large window providing a view of the outdoors.

A hotel room with a bed, a sink, a microwave, and a window with curtains.

A reception area with a curved counter, ceiling lights, and a potted plant.

A paved garden area with two benches, a potted plant with yellow flowers, and a variety of greenery.

16. Brentwood Inn & Suites

Downtown Rochester, 0.3 km from Mayo Clinic

Daniel

AU$155

includes taxes & fees

29 Oct - 30 Oct

A hotel entrance with a stone facade, a glass door, and a metal roof structure.

A hotel lobby with striped armchairs, a sofa, a fireplace, and a clock on the wall.

A spa area with a hot tub, exercise equipment, and a seating area with chairs and a table.

An outdoor patio area with brick walls, a large arched window, and outdoor seating.

17. Aspen Suites

1.2 km from Mayo Clinic

Dana

AU$232

includes taxes & fees

23 Oct - 24 Oct

A hotel breakfast area with a self-serve station, including a waffle maker, toaster, and various food items.

A modern living room with a sofa, coffee table, and a TV mounted on a stone wall.

A compact kitchen with a microwave, refrigerator, and coffee maker. A small bar stool is near the counter.

A hotel room with a large bed, bedside tables, a mirror, and a patterned carpet.

18. Quality Inn & Suites Mayo Clinic Area

2.6 km from Mayo Clinic

Jessica

AU$127

includes taxes & fees

1 Nov - 2 Nov

A spacious hotel lobby with multiple seating areas, including sofas and round tables, and a large dining area with yellow chairs.

A hotel room with a blue sofa, a wooden bench, a small table with a lamp, a painting of a flower, and a kitchenette in the background.

A grocery store with refrigerated and frozen sections, shelves stocked with snacks, and a variety of beverages.

A spacious lobby with a large seating area, a fireplace, and large windows providing natural light.

19. Hilton Garden Inn Rochester Downtown, MN

Downtown Rochester, 0.3 km from Mayo Clinic

Richard

AU$195

includes taxes & fees

23 Oct - 24 Oct

An outdoor patio area with yellow umbrellas, wicker furniture, and a sign for Centerstone Plaza Hotel.

A modern reception area with a wooden reception desk, glass pendant lights, and a long hallway with seating.

A restaurant interior with wooden tables, chairs, and a stone wall.

A modern living room with a dark wall, a decorative light fixture, and a patterned wall art piece.

20. Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

Historic Southwest, 0.6 km from Mayo Clinic

Christine

AU$178

includes taxes & fees

10 Oct - 11 Oct

View all properties

Compare popular hotels close to Mayo Clinic

Property	Property class	Guest rating
Home2 Suites by Hilton Rochester Mayo Clinic Area	9.6 Exceptional 1,000 reviews	View
The Berkman	9.6 Exceptional 447 reviews	View
Hilton Rochester Mayo Clinic Area	9.6 Exceptional 649 reviews	View
Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys	9.6 Exceptional 742 reviews	View
TownePlace Suites by Marriott Rochester Mayo Clinic Area	9.6 Exceptional 564 reviews	View

Top Mayo Clinic Hotel Reviews

Kahler Inn and Suites - Mayo Clinic Area

10/10 Excellent

"Location"

Kahler Grand Hotel

10/10 Excellent

"Best price and location with options for parking."

Hotel Indigo Rochester – Mayo Clinic Area by IHG

10/10 Excellent

"Great location. Great accommodations. Highly recommended."

Hyatt House Rochester/Mayo Clinic Area

10/10 Excellent

"The room was very clean. Staff were kind and pleasant upon check in."

Staybridge Suites Rochester - Mayo Clinic Area by IHG

10/10 Excellent

"Absolutely perfect hotel, especially if you are traveling back and forth to St. Mary’s campus for Mayo. Great breakfast, free laundry, great shower, comfy bed. Best you could get in these circumstances away from home. Thank you!"

SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys

8/10 Good

"Staff was good, rooms were clean but needing some updates"

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

8/10 Good

"Excellent location. Great shuttle service to mayo gonna. No working wifi in my room but other than that was fine."

TownePlace Suites by Marriott Rochester Mayo Clinic Area

10/10 Excellent

"The rooms were very nice and clean, and the staff was extremely helpful. As I was traveling alone with a child, I appreciated the safety measures the hotel had in place, which I don't often see in other hotels. The parking garage was fully enclosed, with access limited to room key entry only. You also needed your room key to operate the elevators. Since we travel to the area for appointments from time to time, this will be our go-to hotel whenever we visit."

Frequently asked questions

What are the top-rated hotels near Mayo Clinic?

Discovering the top-rated hotels near Mayo Clinic ensures a comfortable and convenient stay during your visit to Rochester, Minnesota.Home2 Suites by Hilton Rochester Mayo Clinic AreaHome2 Suites by Hilton Rochester Mayo Clinic Area is a welcoming 3-star hotel located just 4.5 km from Mayo Clinic, rated 9.6 by travellers. Guests appreciate the modern amenities, including a kitchenette with a dishwasher and microwave, as well as a cozy sofa bed. The hotel features complimentary daily breakfast and an accessible indoor pool, making it a perfect choice for those seeking a relaxed atmosphere. With additional perks like Egyptian cotton sheets and a fitness centre, this hotel ensures comfort and convenience for every traveler.Residence Inn by Marriott Rochester Mayo Clinic Area SouthResidence Inn by Marriott Rochester Mayo Clinic Area South is another excellent option, situated 4.5 km from Mayo Clinic and a review rating of 9.6. This 3-star hotel offers spacious rooms with full kitchens and a convenient wet bar, ideal for longer stays. Guests can enjoy a complimentary breakfast and take advantage of the indoor pool and hot tub. The fitness centre is accessible 24 hours, ensuring travellers can maintain their routine while away from home.Fairfield Inn & Suites Rochester Mayo Clinic Area/St. MarysFairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys is perfectly located just 2.4 km from Mayo Clinic, earning an impressive review rating of 9.6. This hotel features comfortable suites and an inviting atmosphere, complete with an indoor pool and a rooftop garden for relaxation. Guests can enjoy complimentary breakfast and easy access to an onsite tennis court, making it a great choice for those looking to stay active during their visit.

What hotels are within walking distance to Mayo Clinic?

Discover the convenience of top-rated hotels within walking distance to Mayo Clinic, perfect for travellers seeking comfort and accessibility.Hilton Rochester Mayo Clinic AreaHilton Rochester Mayo Clinic Area is a welcoming 3.5-star hotel located just a 6-minute walk from Mayo Clinic, with an impressive review rating of 9.6. This hotel features an indoor pool, a full-service spa offering massages and aromatherapy treatments, and a fitness centre open 24 hours. Guests can also enjoy relaxing moments in the hot tub and steam room, making it an excellent choice for relaxation after a day at the clinic.TownePlace Suites by Marriott Rochester Mayo Clinic AreaTownePlace Suites by Marriott Rochester Mayo Clinic Area is a cozy 3-star hotel that is only a 5-minute stroll from Mayo Clinic, rated 9.6 by travellers. It offers a complimentary buffet breakfast and 24-hour fitness facilities. Guests appreciate the rooftop garden and the convenience of in-room kitchens, perfect for those looking to prepare their own meals. The hotel also provides free area shuttle services, adding to its overall convenience for travellers.Staybridge Suites Rochester - Mayo Clinic Area by IHGStaybridge Suites Rochester - Mayo Clinic Area by IHG is a comfortable 3-star hotel located a 12-minute walk from Mayo Clinic, with a solid review rating of 9.4. This hotel features an indoor pool and a hot tub, along with spacious suites equipped with kitchens and premium bedding. Guests can enjoy a complimentary breakfast daily and take advantage of the free area shuttle service, making it an ideal base for those visiting the clinic.

What are the most popular family-friendly hotels near Mayo Clinic?

For families visiting Mayo Clinic, finding the perfect family-friendly hotel is essential for a comfortable stay. Here are some of the top-rated options that cater to families.Centerstone Plaza Hotel Soldiers Field - Mayo Clinic AreaLocated just an 8-minute walk from Mayo Clinic, the Centerstone Plaza Hotel Soldiers Field is a family-friendly haven with a review rating of 8.4 and a 3-star rating. This hotel features an indoor pool with a children's area, free daily breakfast, and kitchens in select rooms, perfect for families. Guests will appreciate the comfortable accommodations and easy access to the clinic.Med City Inn & Suites - Mayo Clinic AreaMed City Inn & Suites offers an inviting atmosphere just 2.1 km from Mayo Clinic, perfect for families. With a great traveler rating score of 8.0, this hotel features a fantastic waterslide and a children's pool to keep the little ones entertained. Guests can also enjoy complimentary breakfast, a kitchenette in the rooms, and a game room designed for family fun, ensuring a memorable stay.Kahler Grand HotelJust a 3-minute walk from Mayo Clinic, Kahler Grand Hotel is an ideal family-friendly choice with a review rating of 8.2 and a 3-star rating. Families will enjoy amenities like free cribs, connecting rooms, and a children's menu at the on-site restaurant. With its indoor pool and convenient location, travellers can easily balance relaxation and access to the clinic.

What are the best affordable hotels near Mayo Clinic?

Finding a budget-friendly hotel near Mayo Clinic can enhance your stay and provide peace of mind during your visit. Here are some top-rated options that offer great amenities without breaking the bank.Home2 Suites by Hilton Rochester Mayo Clinic AreaHome2 Suites by Hilton Rochester Mayo Clinic Area is a 3-star hotel located just 4.5 km from Mayo Clinic, with an impressive review rating of 9.6. This family-friendly hotel features complimentary breakfast daily, including a buffet on weekends, and offers a variety of amenities such as a fitness centre, free WiFi, and a kitchenette in each suite. Guests can also enjoy the convenience of free area shuttle service and on-site grocery shopping service.Residence Inn by Marriott Rochester Mayo Clinic Area SouthResidence Inn by Marriott Rochester Mayo Clinic Area South is another excellent 3-star option, situated 4.5 km from Mayo Clinic with a stellar review rating of 9.6. Ideal for families, this hotel features a complimentary continental breakfast and an indoor pool perfect for relaxation. Guests will appreciate the fully equipped kitchens in the suites, free WiFi, and accessible fitness facilities to maintain their routine while traveling.Fairfield Inn & Suites Rochester Mayo Clinic Area/St. MarysFairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys stands out with a prime location just 2.4 km from Mayo Clinic and a popular review rating of 9.6. This family-friendly hotel offers free breakfast options and access to an indoor pool, making it a great choice for leisure and relaxation. Additional amenities include free parking, WiFi, and a fitness centre, ensuring travellers have all they need for a comfortable stay.

Are there any hotels with pools close to Mayo Clinic?

If you're looking for hotels with pools near Mayo Clinic, Rochester offers some great options that cater to travellers seeking relaxation and comfort during their stay.Centerstone Plaza Hotel Soldiers Field - Mayo Clinic AreaCenterstone Plaza Hotel Soldiers Field - Mayo Clinic Area is located only 8 minutes from Mayo Clinic and has an excellent review rating of 8.4. This hotel offers an indoor pool with features for children and accessibility options. Guests can also take advantage of free buffet breakfast, 24-hour fitness facilities, and easy access to nearby golf courses and historical sites.Best Western Rochester Hotel Mayo Clinic Area/St. Mary'sBest Western Rochester Hotel Mayo Clinic Area/St. Mary's is conveniently located just 3.5 km from Mayo Clinic, making it an ideal choice for travellers. With an impressive review rating of 8.2, this hotel features an indoor pool complete with a waterslide and children's area—perfect for families. Guests can also enjoy free breakfast, a hot tub, and easy access to local golf courses.Kahler Inn and Suites - Mayo Clinic AreaKahler Inn and Suites - Mayo Clinic Area is just a 3-minute walk from Mayo Clinic and boasts a great traveler rating score of 7.8. This family-friendly hotel features an indoor pool with accessibility options, making it suitable for everyone. Guests can enjoy amenities like a kitchenette in the rooms, free breakfast, and covered parking, ensuring a comfortable stay.

What are the best pet-friendly hotels near Mayo Clinic?

For travellers seeking pet-friendly accommodations near the Mayo Clinic, these top-rated hotels offer welcoming stays for both you and your furry friend.Residence Inn by Marriott Rochester Mayo Clinic Area SouthResidence Inn by Marriott stands out with an impressive 9.6 travellers' rating and is located 4.5 km from the Mayo Clinic. This 3-star hotel allows both dogs and cats, making it a perfect choice for travellers with pets. Guests will appreciate the complimentary breakfast, an indoor pool, and a fitness centre. Additional features include a fully equipped kitchen in every suite and convenient parking options.Centerstone Plaza Hotel Soldiers Field - Mayo Clinic AreaCenterstone Plaza Hotel Soldiers Field is just an 8-minute walk from the Mayo Clinic and has a welcoming atmosphere for pets, earning a review rating of 8.4. This 3-star hotel features an indoor pool, free buffet breakfast, and a fitness centre. Guests can also enjoy nearby golf, a terrace, and family-friendly amenities such as cribs and kid-friendly meals.Med City Inn & Suites - Mayo Clinic AreaMed City Inn & Suites is a cozy and inviting option just 2.1 km from the Mayo Clinic, with a solid review rating of 8.0. This pet-friendly hotel welcomes dogs and offers essential amenities like free breakfast, an indoor pool, and a hot tub, ensuring a comfortable stay. Guests can also enjoy a fitness centre, kitchenette options, and complimentary toiletries.

Can I cancel my hotel reservation on Expedia?

You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if cancelled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels near Mayo Clinic.

Can I find Expedia discounts for hotels near Mayo Clinic?

To look for discounts on hotels near Mayo Clinic, join One Key™—our free travel rewards program. One Key members unlock instant discounts with Member Prices and earn OneKeyCash™* on eligible bookings. Another way you could save is by bundling your hotel and flights together on Expedia. *Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.

How much is the nightly rate for a hotel near Mayo Clinic?

Prices for hotels near Mayo Clinic often vary, but you can find a great deal from AU$109 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for our cheapest rates.

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Our top choices for Mayo Clinic hotels

1. Home2 Suites by Hilton Rochester Mayo Clinic Area

2. The Berkman

3. Hilton Rochester Mayo Clinic Area

4. Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys

5. TownePlace Suites by Marriott Rochester Mayo Clinic Area

6. Residence Inn by Marriott Rochester Mayo Clinic Area South

7. EVEN Hotel Rochester - Mayo Clinic Area by IHG

8. Staybridge Suites Rochester - Mayo Clinic Area by IHG

9. Broadway Plaza, Trademark Collection by Wyndham

10. Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys

11. Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys

12. Hyatt House Rochester/Mayo Clinic Area

13. Candlewood Suites Rochester Mayo Clinic Area by IHG

14. Econo Lodge Mayo Clinic Area

15. Hampton Inn Rochester-South

16. Brentwood Inn & Suites

17. Aspen Suites

18. Quality Inn & Suites Mayo Clinic Area

19. Hilton Garden Inn Rochester Downtown, MN

20. Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

Compare popular hotels close to Mayo Clinic

Top Mayo Clinic Hotel Reviews

Kahler Inn and Suites - Mayo Clinic Area

Kahler Grand Hotel

Hotel Indigo Rochester – Mayo Clinic Area by IHG

Hyatt House Rochester/Mayo Clinic Area

Staybridge Suites Rochester - Mayo Clinic Area by IHG

SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

TownePlace Suites by Marriott Rochester Mayo Clinic Area

Frequently asked questions

Explore a world of travel with Expedia

Top Hotels Near Mayo Clinic in Rochester from AU$109

Check prices for these dates

Filter by

Property class

Guest rating

Our top choices for Mayo Clinic hotels

1. Home2 Suites by Hilton Rochester Mayo Clinic Area

2. The Berkman

3. Hilton Rochester Mayo Clinic Area

4. Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys

5. TownePlace Suites by Marriott Rochester Mayo Clinic Area

6. Residence Inn by Marriott Rochester Mayo Clinic Area South

7. EVEN Hotel Rochester - Mayo Clinic Area by IHG

8. Staybridge Suites Rochester - Mayo Clinic Area by IHG

9. Broadway Plaza, Trademark Collection by Wyndham

10. Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys

11. Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys

12. Hyatt House Rochester/Mayo Clinic Area

13. Candlewood Suites Rochester Mayo Clinic Area by IHG

14. Econo Lodge Mayo Clinic Area

15. Hampton Inn Rochester-South

16. Brentwood Inn & Suites

17. Aspen Suites

18. Quality Inn & Suites Mayo Clinic Area

19. Hilton Garden Inn Rochester Downtown, MN

20. Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

Compare popular hotels close to Mayo Clinic

Top Mayo Clinic Hotel Reviews

Kahler Inn and Suites - Mayo Clinic Area

Kahler Grand Hotel

Hotel Indigo Rochester – Mayo Clinic Area by IHG

Hyatt House Rochester/Mayo Clinic Area

Staybridge Suites Rochester - Mayo Clinic Area by IHG

SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

TownePlace Suites by Marriott Rochester Mayo Clinic Area

Frequently asked questions

Explore a world of travel with Expedia