10 Best Hotels & Accommodation Closest to Mayo Clinic Florida in Jacksonville from AU$147

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Our top choices for Mayo Clinic Florida hotels

A modern restaurant with a bar area, wooden ceiling, and large windows.

A modern lobby with a central seating area, wooden shelving with decorative items, and a large pillar.

A covered outdoor seating area with chairs and sofas, a fountain, and a view of a lake and trees.

A modern bar area with a central hanging light fixture, bar stools, and a well-stocked liquor display.

1. Hilton Jacksonville at Mayo Clinic near Beaches

0.8 km from Mayo Clinic Florida

Kristen

AU$247

includes taxes & fees

20 Sept - 21 Sept

An outdoor seating area with a fire pit, wicker furniture, and a covered patio.

A modern kitchen with wooden cabinets, a built-in oven, and a coffee machine.

A multi-story hotel with a modern design, featuring a covered outdoor area with seating and a fire pit.

A hotel room with a bed, a sofa, a nightstand, and a wall-mounted lamp.

2. TownePlace Suites by Marriott Jacksonville East

Golden Glades - The Woods, 3.1 km from Mayo Clinic Florida

gregory

AU$189

includes taxes & fees

4 Oct - 5 Oct

A lobby with a reception desk, seating area, and a staircase.

A modern kitchen with a refrigerator, coffee machine, and a bakery display.

A modern hotel room with a large bed, a blue sofa, a small table, and a wall-mounted lamp.

3. Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG

2.6 km from Mayo Clinic Florida

Sam

AU$163

includes taxes & fees

11 Oct - 12 Oct

A hotel lobby with a bar area, seating arrangements, and a reception desk.

A hotel room with a bed, a desk, a sofa, and a small table. There is a mirror, a lamp, and a picture on the wall.

An outdoor patio with a brick wall, a round table with striped chairs, and two large umbrellas.

A hotel pool area with a long, narrow pool, multiple lounge chairs, and a covered seating area.

4. Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic

Golden Glades - The Woods, 3.1 km from Mayo Clinic Florida

Patsy

AU$174

includes taxes & fees

4 Oct - 5 Oct

An outdoor seating area with stone fire pit, wicker furniture, and potted plants.

A modern hotel lobby with a flat-screen TV, a fireplace, comfortable seating, and a coffee bar.

A modern living room with two armchairs, a sofa, a coffee table, and a flat-screen TV mounted on the wall.

A hotel pool area with lounge chairs and umbrellas, surrounded by multi-story buildings with balconies.

5. Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches

0.4 km from Mayo Clinic Florida

Troy

AU$241

includes taxes & fees

26 Sept - 27 Sept

A backyard with a swimming pool, wooden deck, and outdoor furniture.

A compact kitchen with a refrigerator, microwave, and a dining area with a table and chairs.

A hotel room with two beds, a floral wallpaper, a ceiling light, and a wall-mounted air conditioner.

A wooden fence with a blue and white striped umbrella, two green lounge chairs, and a white chair.

6. Hotel Palms

7.8 km from Mayo Clinic Florida

Vinny

AU$223

includes taxes & fees

15 Sept - 16 Sept

A multi-story hotel with a modern design, featuring a covered entrance and a parking area with handicapped accessibility.

A breakfast bar with a digital menu display, various food dispensers, and a yogurt machine.

A hotel room with two beds, a desk, a chair, and a large window with a view.

A coastal cityscape with a long beach, a large hotel with a curved facade, and a clear sky.

7. Holiday Inn Express & Suites Jacksonville - Town Center by IHG

Southside, 7.7 km from Mayo Clinic Florida

Chernda

AU$208

includes taxes & fees

20 Sept - 21 Sept

An outdoor patio area with seating, a fire pit, and a barbecue grill.

A modern hotel with a sign reading "Towneplace Suites by Marriott" and a parking lot in front.

A modern living room with sofas, a coffee table, and a dining area.

A modern kitchen with wooden cabinets, a central island with jars, and a countertop with toasters.

8. TownePlace Suites by Marriott® Jacksonville Mayport

10.8 km from Mayo Clinic Florida

irina

AU$187

includes taxes & fees

20 Sept - 21 Sept

A modern outdoor seating area with white wicker chairs, a glass fire pit with burning wood, and a view of palm trees and a building in the background.

A modern conference room with a long table, several chairs, and pendant lighting.

A pathway leading to a sunset over a beach with sand and grass.

A modern hotel lobby with a long reception desk, seating area, and large windows.

9. Element by Marriott Jacksonville Beach

5.4 km from Mayo Clinic Florida

Nick

AU$228

includes taxes & fees

4 Oct - 5 Oct

A laptop on a wooden desk with a white mug, a spoon, and a smartphone.

A kitchen counter with a coffee maker, a blender, a book titled 'CHECKERS,' and a water bottle.

10. Hyatt Studios Jacksonville/St Johns Town Center

Deerwood, 7.8 km from Mayo Clinic Florida

Phi

AU$174

includes taxes & fees

3 Oct - 4 Oct

A spacious lobby with a central seating area, large windows, and a fountain.

A spacious lobby with high ceilings, wooden beams, and a central chandelier.

A hotel room with two beds, a desk, a chair, a TV, and a view of the ocean.

A beach umbrella with two chairs underneath, a sandy beach, and the ocean in the background.

11. Ponte Vedra Inn & Club

6.3 km from Mayo Clinic Florida

Michael

AU$816

includes taxes & fees

16 Sept - 17 Sept

A spacious lobby with a reception desk, seating area, and large windows.

A bar area with wooden chairs, a round table, and a brick wall.

A multi-story hotel with a central entrance, large windows, and a well-lit facade.

A modern coffee shop interior with a central counter, shelves stocked with snacks, and a refrigerated section labeled 'FROZEN' and 'CHILLED'.

12. Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass

8.5 km from Mayo Clinic Florida

Brooke

AU$200

includes taxes & fees

23 Sept - 24 Sept

A modern bar area with a central island, multiple seating options, and a variety of bottles displayed on shelves.

An outdoor seating area with white furniture and a well-maintained lawn, surrounded by large windows and a modern building facade.

A modern hotel building with a flat facade, large windows, and a sign reading "ACHTEL JACKSONVILLE".

A modern bar area with seating, a bar counter, and a view of the city through large windows.

13. AC Hotel Jacksonville St Johns Town Center

Southside, 8.1 km from Mayo Clinic Florida

Alysha

AU$284

includes taxes & fees

13 Sept - 14 Sept

An outdoor seating area with a fire feature, chairs, and a table.

A modern bar area with a counter, bar stools, and a television screen.

A modern bar area with a curved counter, multiple bar stools, and a variety of liquor bottles.

A gym with treadmills, dumbbells, and exercise balls, overlooking a swimming pool.

14. Hotel Indigo Jacksonville-Deerwood Park by IHG

Southside, 10.8 km from Mayo Clinic Florida

Carol

AU$201

includes taxes & fees

17 Sept - 18 Sept

A pool with a waterfall feature, surrounded by large rock formations.

A balcony with a view of the ocean, a chair, and a railing.

A beachfront hotel with multiple balconies, a sandy beach, and ocean views.

A hotel with a pool, a parking lot, and a view of the ocean.

15. Hampton Inn Jacksonville Beach/Oceanfront

6.3 km from Mayo Clinic Florida

Susan

AU$261

includes taxes & fees

4 Oct - 5 Oct

A spacious lobby with a glass floor, a reception desk, and a view of the ocean.

A bar area with a view of the beach, wooden bar stools, and a counter with a menu display.

A multi-story hotel with a beach view, parking lot, and a nearby restaurant.

A modern building with multiple balconies overlooking a beach.

16. Margaritaville Jacksonville Beach

5.9 km from Mayo Clinic Florida

Melissa

AU$237

includes taxes & fees

13 Sept - 14 Sept

An outdoor patio with blue and red chairs, tables, and potted plants.

A hotel room with a bed, a desk with a microwave, a coffee maker, and a mini-fridge.

A room with a window, a sofa, and an air conditioning unit.

A rectangular swimming pool with a tiled deck, surrounded by a black metal fence. There are lounge chairs with blue cushions and white frames along the pool's edge.

17. Holiday Inn Express Jacksonville South Bartram Prk by IHG

17.1 km from Mayo Clinic Florida

John

AU$147

includes taxes & fees

13 Sept - 14 Sept

An outdoor patio area with wicker furniture, a fire feature, and string lights.

A modern hotel lobby with a gray sofa, a round wooden table, and a blue armchair. A large abstract painting and a mirror with a vase are on the wall.

A restaurant with long communal tables and booths, large windows, and pendant lighting.

An indoor swimming pool with clear water, surrounded by lounge chairs and tables, large windows offering views of greenery outside.

18. Sheraton Jacksonville Hotel

Deerwood, 9.6 km from Mayo Clinic Florida

Danielle

AU$194

includes taxes & fees

19 Sept - 20 Sept

A self-service beverage station with a refrigerated display and a coffee machine.

A snack display in a store with various chips and snacks.

A modern hotel reception area with a curved wooden reception desk, a digital display, and a view of the lobby.

A modern lounge area with seating, tables, and hanging lights.

19. Tru By Hilton Jacksonville St Johns Town Center

Southside, 8.7 km from Mayo Clinic Florida

Jennifer

AU$174

includes taxes & fees

20 Sept - 21 Sept

A modern bar area with wooden accents, a variety of beverages, and seating arrangements.

A modern bar area with a wooden counter, multiple seating options including bar stools and round tables, and a menu board.

A multi-story hotel with a prominent entrance, a parking lot, and well-maintained landscaping.

A patio area with a stone fire pit, outdoor furniture, and a brick floor.

20. Courtyard by Marriott Jacksonville I-295/East Beltway

Arlington, 13.2 km from Mayo Clinic Florida

Chloie Marie

AU$174

includes taxes & fees

17 Sept - 18 Sept

View all properties

Compare popular hotels close to Mayo Clinic Florida

Property	Property class	Guest rating
Hilton Jacksonville at Mayo Clinic near Beaches	9.4 Exceptional 352 reviews	View
TownePlace Suites by Marriott Jacksonville East	9.2 Wonderful 658 reviews	View
Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG	9.0 Wonderful 1,016 reviews	View
Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic	9.0 Wonderful 1,001 reviews	View
Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches	8.4 Very good 796 reviews	View

Top Mayo Clinic Florida Hotel Reviews

Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area

10/10 Excellent

"Wanted to mention one staff member in particular her name was Chris and she was absolutely delightful!!! I was in the property management business for 40years and I would have hired her in a heartbeat… She’s a keeper and needs to be recognized for a potential management position…"

Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic

8/10 Good

"Had to request daily maid service and clean sheets daily. Didn't always clean the bathroom completely leaving wet washcloths in the shower and didn't always restock usual number of towels. Depending on who cleaned the room friend on how many towels were left. Frustrating."

TownePlace Suites by Marriott Jacksonville East

10/10 Excellent

"Great location close to the beach. Super well maintained facility. Everything was great!"

Stylish Retreat Near Beaches & Attractions - Private, Clean, Comfortable

8/10 Good

"The location was perfect for us, as I had appointments at Mayo Clinic. Leo was a great host and addressed our concerns promptly."

Light Grey Getaway under 2 miles to mayo, 4 miles to the beach

10/10 Excellent

"We could not have been more pleased! Cute neighborhood, 10 minutes to Jacksonville beach! House had everything we needed. Any questions were answered immediately . Beds were comfortable and plenty of room. We had 8 adults and did not feel crowded at all. Kitchen was well stocked. We loved having beach chairs and towels. It made it so easy to just come and play at the beach. Thanks for such a great stay."

Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches

10/10 Excellent

"Great service all around. The bus driver to the clinic was awesome!!’n"

Heated Pool Family Fun Minutes to Mayo & Jax Beach

10/10 Excellent

"We had a fantastic time at this property! It was perfect for our trip."

Comfy Mayo Retreat: Pool & Close to Beach

10/10 Excellent

"Great location with a really nice park close by to walk the dogs. The pool was perfect!"

Beach Retreat in Jacksonville: Pet/Family-Friendly

10/10 Excellent

"Our stay was great there was plenty of room for our group of 12. The house was clean and the pool was a huge hit."

Frequently asked questions

What's the area like around Mayo Clinic Florida?

Mayo Clinic Florida is located in a welcoming area of Jacksonville known for its beautiful beaches and surfing. If you're looking for a convenient place to stay, take a look at the 45 hotels and other accommodation options you'll find within a mile.

Where is the best place to stay close to Mayo Clinic Florida?

Adjacent to Mayo Clinic Florida, Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches is one of the top choices for your stay based on our traveller data, and this hotel offers a restaurant and an outdoor pool. Other good choices close by include Hilton Jacksonville at Mayo Clinic near Beaches and Residence Inn By Marriott Jacksonville - Mayo Clinic Area.

How many hotels are there near Mayo Clinic Florida?

Expedia has 45 hotels and other accommodation options within a mile from Mayo Clinic Florida.

If I need to cancel the hotel reservation for my stay near Mayo Clinic Florida, will I receive a refund?

Yes! You'll find that most hotel bookings are fully refundable as long as you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you have a non-refundable reservation, you may still be able to cancel and get a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then use the "fully refundable" filter to view the top deals on offer near Mayo Clinic Florida.

What can I see and do near Mayo Clinic Florida?

You can catch a show at Wilson Center For the Arts, Blue Jay Listening Room and Players by the Sea. Spend some time exploring the the natural beauty of Huguenot Park, Oceanfront Park and Cradle Creek Preserve. Lounge by the water at Northeast Florida Beaches and Ponte Vedra Beach.

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Activities in St. Augustine

Top Hotels Near Mayo Clinic Florida in Jacksonville from AU$147

Change your mind

Treat yourself

Be picky

Check prices for these dates

Filter by

Property class

Guest rating

Our top choices for Mayo Clinic Florida hotels

1. Hilton Jacksonville at Mayo Clinic near Beaches

2. TownePlace Suites by Marriott Jacksonville East

3. Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG

4. Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic

5. Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches

6. Hotel Palms

7. Holiday Inn Express & Suites Jacksonville - Town Center by IHG

8. TownePlace Suites by Marriott® Jacksonville Mayport

9. Element by Marriott Jacksonville Beach

10. Hyatt Studios Jacksonville/St Johns Town Center

11. Ponte Vedra Inn & Club

12. Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass

13. AC Hotel Jacksonville St Johns Town Center

14. Hotel Indigo Jacksonville-Deerwood Park by IHG

15. Hampton Inn Jacksonville Beach/Oceanfront

16. Margaritaville Jacksonville Beach

17. Holiday Inn Express Jacksonville South Bartram Prk by IHG

18. Sheraton Jacksonville Hotel

19. Tru By Hilton Jacksonville St Johns Town Center

20. Courtyard by Marriott Jacksonville I-295/East Beltway

Compare popular hotels close to Mayo Clinic Florida

Top Mayo Clinic Florida Hotel Reviews

Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area

Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic

TownePlace Suites by Marriott Jacksonville East

Stylish Retreat Near Beaches & Attractions - Private, Clean, Comfortable

Light Grey Getaway under 2 miles to mayo, 4 miles to the beach

Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches

Heated Pool Family Fun Minutes to Mayo & Jax Beach

Comfy Mayo Retreat: Pool & Close to Beach

Beach Retreat in Jacksonville: Pet/Family-Friendly

Frequently asked questions

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