JACKSONVILLE RIVERWALK, FL

Top Hotels Near Mayo Clinic Florida in Jacksonville from AU$171

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Mayo Clinic Florida hotels

Residence Inn By Marriott Jacksonville - Mayo Clinic Area

Residence Inn By Marriott Jacksonville - Mayo Clinic Area
3.0 star property
1.1 km from Mayo Clinic Florida
9.4 out of 10, Exceptional, (537 reviews)
"My family stayed here. Clean hotel and great breakfast."
United States
Ryan
The price is AU$262
includes taxes & fees
19 June - 20 June
Residence Inn By Marriott Jacksonville - Mayo Clinic Area

Hilton Jacksonville At Mayo Clinic

Hilton Jacksonville At Mayo Clinic
4.5 star property
0.8 km from Mayo Clinic Florida
9.4 out of 10, Exceptional, (252 reviews)
"Beautiful hotel!! It was extremely quiet and we all slept amazing!!"
United States
christine
The price is AU$263
includes taxes & fees
3 July - 4 July
Hilton Jacksonville At Mayo Clinic

Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG

Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG
2.5 star property
2.6 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (1,027 reviews)
"Everyone was very nice and the rooms were clean."
United States
Camille
The price is AU$198
includes taxes & fees
21 June - 22 June
Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG

Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic

Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic
2.5 star property
Golden Glades - The Woods, 3.1 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (1,012 reviews)
"Nice clean easy stay. Staff interaction was all positive as well. Decent breakfast too."
United States
Heidi
The price is AU$171
includes taxes & fees
21 June - 22 June
Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic

Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches

Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches
3.0 star property
0.4 km from Mayo Clinic Florida
8.4 out of 10, Very good, (777 reviews)
"Enjoyed our stay"
United States
Alan
The price is AU$245
includes taxes & fees
20 June - 21 June
Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches

Hyatt Studios Jacksonville/St Johns Town Center

Hyatt Studios Jacksonville/St Johns Town Center
2.5 star property
Deerwood, 7.8 km from Mayo Clinic Florida
9.6 out of 10, Exceptional, (79 reviews)
"Great staff, new hotel, a pleasure to stay in"
United States
Kevin
The price is AU$190
includes taxes & fees
15 June - 16 June
Hyatt Studios Jacksonville/St Johns Town Center

Element by Marriott Jacksonville Beach

Element by Marriott Jacksonville Beach
3.0 star property
5.4 km from Mayo Clinic Florida
9.6 out of 10, Exceptional, (562 reviews)
"Best hotel ever 😊"
United States
Tablo
The price is AU$245
includes taxes & fees
21 June - 22 June
Element by Marriott Jacksonville Beach

Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area

Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area
2.5 star property
4.2 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (1,138 reviews)
"Great location not too far from beaches restsurants, and shopping."
United States
Donna L.
The price is AU$219
includes taxes & fees
30 June - 1 July
Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area

The Hotel Palms Poolside

The Hotel Palms Poolside
2.5 star property
7.8 km from Mayo Clinic Florida
9.8 out of 10, Exceptional, (480 reviews)
"Very clean and quiet, even with the festival in AB. Felt very safe. Loved the pool area!"
United States
Liza
The price is AU$291
includes taxes & fees
14 June - 15 June
The Hotel Palms Poolside

Holiday Inn Express Jacksonville Beach by IHG

Holiday Inn Express Jacksonville Beach by IHG
3.0 star property
4.6 km from Mayo Clinic Florida
9.2 out of 10, Wonderful, (1,004 reviews)
"The hotel and the staff were amazing! My family had a wonderful time there, the rooms were clean and a good breakfast! Excellent location!"
United States
Maria
The price is AU$201
includes taxes & fees
21 June - 22 June
Holiday Inn Express Jacksonville Beach by IHG

The Hotel Palms Courtyard

The Hotel Palms Courtyard
3.5 star property
7.8 km from Mayo Clinic Florida
9.6 out of 10, Exceptional, (302 reviews)
"Clean, room was very nice, staff was helpful"
United States
Angela
The price is AU$278
includes taxes & fees
14 June - 15 June
The Hotel Palms Courtyard

Margaritaville Jacksonville Beach

Margaritaville Jacksonville Beach
2.5 star property
5.9 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (4,060 reviews)
"Great room and very convenient location"
United States
Lyndi
The price is AU$269
includes taxes & fees
15 June - 16 June
Margaritaville Jacksonville Beach

AC Hotel Jacksonville St Johns Town Center

AC Hotel Jacksonville St Johns Town Center
2.5 star property
Southside, 8.1 km from Mayo Clinic Florida
9.4 out of 10, Exceptional, (208 reviews)
"Great stay! Highly recommend and tons to do in the area."
United States
Adam
The price is AU$288
includes taxes & fees
13 June - 14 June
AC Hotel Jacksonville St Johns Town Center

The Lodge and Club at Ponte Vedra Beach

The Lodge and Club at Ponte Vedra Beach
5.0 star property
6.3 km from Mayo Clinic Florida
9.4 out of 10, Exceptional, (697 reviews)
"Loved the soacious rooms and the beach was very clean"
Canada
Marsha
The price is AU$751
includes taxes & fees
21 June - 22 June
The Lodge and Club at Ponte Vedra Beach

Hyatt Place Jacksonville / St. Johns Town Center

Hyatt Place Jacksonville / St. Johns Town Center
3.0 star property
Southside, 8.6 km from Mayo Clinic Florida
9.2 out of 10, Wonderful, (1,056 reviews)
"Great stay!"
United States
William
The price is AU$205
includes taxes & fees
14 June - 15 June
Hyatt Place Jacksonville / St. Johns Town Center

Best Western Oceanfront

Best Western Oceanfront
3.0 star property
5.7 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (1,003 reviews)
"Great stay"
United States
Adam
The price is AU$232
includes taxes & fees
15 June - 16 June
Best Western Oceanfront

Springhill Suites By Marriott Jacksonville Beach Oceanfront

Springhill Suites By Marriott Jacksonville Beach Oceanfront
4.0 star property
5.8 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (714 reviews)
"Room was clean, lots to do and place to eat close by. Breakfast was good. Overall a good hotel."
United States
Yadiel
The price is AU$320
includes taxes & fees
14 June - 15 June
Springhill Suites By Marriott Jacksonville Beach Oceanfront

Hampton Inn Jacksonville Beach/Oceanfront

Hampton Inn Jacksonville Beach/Oceanfront
3.0 star property
6.3 km from Mayo Clinic Florida
9.2 out of 10, Wonderful, (2,673 reviews)
"Good breakfast and great amenities with the pool, beach and tiki barand grill. "
United States
Hillary
The price is AU$298
includes taxes & fees
28 June - 29 June
Hampton Inn Jacksonville Beach/Oceanfront

Four Points by Sheraton Jacksonville Beachfront

Four Points by Sheraton Jacksonville Beachfront
3.0 star property
5.6 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (1,006 reviews)
"Very nice property and staff"
United States
BONINA
The price is AU$341
includes taxes & fees
21 June - 22 June
Four Points by Sheraton Jacksonville Beachfront

Holiday Inn Express & Suites Jacksonville - Town Center by IHG

Holiday Inn Express & Suites Jacksonville - Town Center by IHG
2.5 star property
Southside, 7.7 km from Mayo Clinic Florida
9.6 out of 10, Exceptional, (1,011 reviews)
"Great place to stay"
United States
Clyde
The price is AU$204
includes taxes & fees
25 June - 26 June
Holiday Inn Express & Suites Jacksonville - Town Center by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels close to Mayo Clinic Florida

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
Lobby
Residence Inn By Marriott Jacksonville - Mayo Clinic Area
3.0 star property
9.4
Exceptional
537 reviews
View
Breakfast, lunch and dinner served
Hilton Jacksonville At Mayo Clinic
4.5 star property
9.4
Exceptional
252 reviews
View
Lobby sitting area
Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG
2.5 star property
9.0
Wonderful
1,027 reviews
View
Lobby
Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic
2.5 star property
9.0
Wonderful
1,012 reviews
View
Terrace/patio
Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches
3.0 star property
8.4
Very good
777 reviews
View

Top Mayo Clinic Florida Hotel Reviews

Frequently asked questions

What's the area like around Mayo Clinic Florida?
Mayo Clinic Florida is located in a welcoming area of Jacksonville known for its beautiful beaches and surfing. If you're looking for a convenient place to stay, take a look at the 45 hotels and other accommodation options you'll find within a mile.
Where is the best place to stay close to Mayo Clinic Florida?
Adjacent to Mayo Clinic Florida, Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches is one of the top choices for your stay based on our traveller data, and this hotel offers a restaurant and an outdoor pool. Other good choices close by include Hilton Jacksonville At Mayo Clinic and Residence Inn By Marriott Jacksonville - Mayo Clinic Area.
How many hotels are there near Mayo Clinic Florida?
Expedia has 45 hotels and other accommodation options within a mile from Mayo Clinic Florida.
If I need to cancel the hotel reservation for my stay near Mayo Clinic Florida, will I receive a refund?
Yes! You'll find that most hotel bookings are fully refundable as long as you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you have a non-refundable reservation, you may still be able to cancel and get a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then use the "fully refundable" filter to view the top deals on offer near Mayo Clinic Florida.
What can I see and do near Mayo Clinic Florida?
You can catch a show at Players by the Sea, SeaWalk Pavillion and Wilson Center For the Arts. Spend some time exploring the the natural beauty of Huguenot Park, Oceanfront Park and Cradle Creek Preserve. Lounge by the water at Northeast Florida Beaches and Ponte Vedra Beach.

Explore a world of travel with Expedia