
Matlacha Isles Hotels, Cape Coral
- Change your mindBook hotels with free cancellation
- Be pickySearch almost a million properties worldwide
Check prices for these dates
Our top choices for Matlacha Isles hotels

Lani Kai Beachfront Resort
Lani Kai Beachfront Resort23.2 km from Matlacha Isles
9.0 out of 10, Wonderful, (1,356 reviews)
The price is AU$280
includes taxes & fees
4 May - 5 May

The Bay Inn at Lani Kai
The Bay Inn at Lani Kai23.1 km from Matlacha Isles
7.6 out of 10, Good, (381 reviews)
The price is AU$273
includes taxes & fees
7 Apr - 8 Apr

Pointe Estero Beach Resort
Pointe Estero Beach Resort28.6 km from Matlacha Isles
9.2 out of 10, Wonderful, (1,002 reviews)
The price is AU$711
includes taxes & fees
3 May - 4 May

MainStay Suites Fort Myers East I-75
MainStay Suites Fort Myers East I-7524.7 km from Matlacha Isles
9.6 out of 10, Exceptional, (332 reviews)
The price is AU$131
includes taxes & fees
6 May - 7 May

The Anchor Inn
The Anchor Inn21.8 km from Matlacha Isles
10.0 out of 10, Exceptional, (17 reviews)
The price is AU$346
includes taxes & fees
29 Apr - 30 Apr

Comfort Suites Fort Myers East I-75
Comfort Suites Fort Myers East I-7524.8 km from Matlacha Isles
9.6 out of 10, Exceptional, (434 reviews)
The price is AU$144
includes taxes & fees
12 Apr - 13 Apr

Park Motel
Park MotelDiplomat, 17.2 km from Matlacha Isles
9.2 out of 10, Wonderful, (45 reviews)
The price is AU$141
includes taxes & fees
7 Apr - 8 Apr

1 Island Hideaway
1 Island Hideaway25.1 km from Matlacha Isles
8.6 out of 10, Excellent, (32 reviews)
The price is AU$644
includes taxes & fees
5 May - 6 May

TownePlace Suites by Marriott Fort Myers Gulf Coast
TownePlace Suites by Marriott Fort Myers Gulf Coast29.9 km from Matlacha Isles
9.2 out of 10, Wonderful, (176 reviews)
The price is AU$205
includes taxes & fees
4 May - 5 May

Sanibel Island Beach Resort
Sanibel Island Beach Resort22.7 km from Matlacha Isles
9.2 out of 10, Wonderful, (1,750 reviews)
The price is AU$416
includes taxes & fees
3 May - 4 May

Comfort Inn Fort Myers Northeast
Comfort Inn Fort Myers Northeast25.8 km from Matlacha Isles
7.8 out of 10, Good, (712 reviews)
The price is AU$117
includes taxes & fees
12 Apr - 13 Apr

StudioRes by Marriott Fort Myers Airport
StudioRes by Marriott Fort Myers Airport29.5 km from Matlacha Isles
9.4 out of 10, Exceptional, (41 reviews)
The price is AU$150
includes taxes & fees
3 May - 4 May

Pink Shell Beach Resort and Marina
Pink Shell Beach Resort and Marina21.7 km from Matlacha Isles
9.4 out of 10, Exceptional, (1,309 reviews)
The price is AU$633
includes taxes & fees
19 Apr - 20 Apr

MALU LANI Inn & Marina
MALU LANI Inn & Marina12.5 km from Matlacha Isles
10.0 out of 10, Exceptional, (5 reviews)
The price is AU$589
includes taxes & fees
7 Apr - 8 Apr

Latitude 26 Waterfront Boutique Resort - Fort Myers Beach
Latitude 26 Waterfront Boutique Resort - Fort Myers Beach20.4 km from Matlacha Isles
8.8 out of 10, Excellent, (1,003 reviews)
The price is AU$200
includes taxes & fees
10 Apr - 11 Apr

Boca Grande Hotel
Boca Grande Hotel28.8 km from Matlacha Isles
8.8 out of 10, Excellent, (619 reviews)
The price is AU$317
includes taxes & fees
6 Apr - 7 Apr

Holiday Inn Express & Suites Fort Myers Airport by IHG
Holiday Inn Express & Suites Fort Myers Airport by IHG29 km from Matlacha Isles
9.6 out of 10, Exceptional, (1,007 reviews)
The price is AU$170
includes taxes & fees
26 Apr - 27 Apr

Extended Stay America Premier Suites - Fort Myers - Airport
Extended Stay America Premier Suites - Fort Myers - Airport23.6 km from Matlacha Isles
8.8 out of 10, Excellent, (925 reviews)
The price is AU$132
includes taxes & fees
12 Apr - 13 Apr

Quality Inn Fort Myers Cape Coral
Quality Inn Fort Myers Cape Coral18.4 km from Matlacha Isles
7.4 out of 10, Good, (286 reviews)
The price is AU$132
includes taxes & fees
22 Apr - 23 Apr

Flamingo Inn
Flamingo Inn27.9 km from Matlacha Isles
7.8 out of 10, Good, (999 reviews)
The price is AU$287
includes taxes & fees
12 Apr - 13 Apr
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Our guide on where to stay in Matlacha Isles
Find the best Matlacha Isles areas for the activities you enjoy most.

Pelican
While visiting Pelican, you might make a stop by sights like Tarpon Point and Chabad Jewish Center.

Caloosahatchee
If you're spending some time in Caloosahatchee, Cape Coral Yacht Club Beach and Dolphin Marina are top sights worth seeing.

Yacht Club
While Yacht Club isn't home to many top sights, Cape Coral Yacht Club Beach and Dolphin Marina are some notable places to visit nearby.

Hancock
While visiting Hancock, you might make a stop by sights like Four Mile Cove Ecological Preserve and Pine Island Shopping Center.
Burnt Store
When in Burnt Store, you can plan a visit to Burnt Store Marina and Royal Tee Golf Club, some noteworthy sights in the nearby area.
Top Matlacha Isles Hotel Reviews

Sanibel Island Beach Resort
10/10 Excellent

















































































