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1 Oct - 2 Oct
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2 Oct - 3 Oct
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2 Oct - 4 Oct
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9 Oct - 11 Oct

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Our top choices for Lyon hotels

1. Hampton Inn Clarksdale

Hampton Inn Clarksdale
Clarksdale
United States
Judy
AU$205
includes taxes & fees
1 Nov - 2 Nov
Hampton Inn Clarksdale

2. Travelers Hotel

Travelers Hotel
Clarksdale
United States
Reade
AU$233
includes taxes & fees
4 Oct - 5 Oct
Travelers Hotel

3. Quality Inn Clarksdale

Quality Inn Clarksdale
Clarksdale
United States
Blu
AU$121
includes taxes & fees
22 Oct - 23 Oct
Quality Inn Clarksdale

4. Americas Best Value Inn & Suites Clarksdale

Americas Best Value Inn & Suites Clarksdale
Clarksdale
United States
Darren
AU$125
includes taxes & fees
2 Oct - 3 Oct
Americas Best Value Inn & Suites Clarksdale

5. Auberge Clarksdale Blues Hostel

Auberge Clarksdale Blues Hostel
Clarksdale
United States
Brian
AU$174
includes taxes & fees
2 Oct - 3 Oct
Auberge Clarksdale Blues Hostel
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Top Lyon Hotel Reviews

Recent Reviews in Lyon

The Sunflower Penthouse on the River in Clarksdale

The Sunflower Penthouse on the River in Clarksdale

8/10 Good
"Great place to stay."
Mark W. 2-night trip
Posted 4 days ago
The Sunflower Penthouse on the River in Clarksdale
Hampton Inn Clarksdale

Hampton Inn Clarksdale

10/10 Excellent
"Staff was so helpful and very friendly and personable."
Jimmy 2-night trip
Posted 11 days ago
Hampton Inn Clarksdale
Only a mile from historic downtown Clarksdale!

Only a mile from historic downtown Clarksdale!

10/10 Excellent
"Nice & quiet place to stay. Perfect for our anniversary weekend."
Jeni H. 1-night trip
Posted 11 days ago
Only a mile from historic downtown Clarksdale!
Get to BLUES-in' at Rusty's Roost, adjacent to downtown Clarksdale, MS

Get to BLUES-in' at Rusty's Roost, adjacent to downtown Clarksdale, MS

10/10 Excellent
"Very clean, very nice and comfortable, very pet friendly, washer and dryer worked well, host was very attentive, and property is very close to everything in clarksdale!!Very pleased!!"
STEPHANIE P. 3-night trip
Posted 1 month ago
Get to BLUES-in' at Rusty's Roost, adjacent to downtown Clarksdale, MS
Sunset Log Cabin

Sunset Log Cabin

10/10 Excellent
"Libby is a very professional and responsive host. The place was perfect for my needs, allowed my dog, easy to get to town, yet also a bit on outskirts so not surrounded by hustle and bustle. Pleasant, rustic vibe, relaxing, and would definitely stay again."
Matt S. 2-night trip
Posted 1 month ago
Sunset Log Cabin
Casa D’Amore!!!!  Adorable home less than 1/2 mile from downtown Clarksdale

Casa D’Amore!!!! Adorable home less than 1/2 mile from downtown Clarksdale

10/10 Excellent
"My go to place to stay when I visit Clarksdale. Has everything you need. Very quiet street and close to everything downtown."
KENNETH M. 5-night trip
Posted 2 months ago
Casa D’Amore!!!! Adorable home less than 1/2 mile from downtown Clarksdale
The Governors Mansion in Clarksdale Mississippi. A Step Back in Time

The Governors Mansion in Clarksdale Mississippi. A Step Back in Time

10/10 Excellent
"There was a total of 15 of us, Siblings with our children. We had a great time with thoroughly enjoyed the pool and all the laughter just hanging out playing games and eating meals together. A great place for a lot of people."
Marietta M. 2-night trip
Posted 2 months ago
The Governors Mansion in Clarksdale Mississippi. A Step Back in Time
Auberge Clarksdale Blues Hostel

Auberge Clarksdale Blues Hostel

10/10 Excellent
"My first time in a hostel and was sort of dreading it, but it was lovely. Shared bathroom was more like a locker room. Great location to walk everywhere."
Shelly 2-night trip
Posted 2 months ago
Auberge Clarksdale Blues Hostel
Cottage on riverbank one mile from Clarksdale in gated community

Cottage on riverbank one mile from Clarksdale in gated community

10/10 Excellent
"The property was very clean, comfortable and check in was so easy, the hospitality was amazing, we really enjoyed ourselves and will be visiting again!!!"
Bridget I. 3-night trip
Posted 3 months ago
Cottage on riverbank one mile from Clarksdale in gated community

More cheap accommodation in Lyon

Quality Inn Clarksdale

Quality Inn Clarksdale

818 South State Street Clarksdale MS
AU$121
22 Oct - 23 Oct
includes taxes & fees
7.2/10 Good! (780 reviews)
Quality Inn Clarksdale
Americas Best Value Inn & Suites Clarksdale

Americas Best Value Inn & Suites Clarksdale

350 South State Street Clarksdale MS
AU$125
2 Oct - 3 Oct
includes taxes & fees
6/10 (432 reviews)
Americas Best Value Inn & Suites Clarksdale
Auberge Clarksdale Blues Hostel

Auberge Clarksdale Blues Hostel

164 Delta Ave Clarksdale MS
AU$174
2 Oct - 3 Oct
includes taxes & fees
9.6/10 Exceptional! (110 reviews)
Auberge Clarksdale Blues Hostel
Hampton Inn Clarksdale

Hampton Inn Clarksdale

15000 New Africa Rd Clarksdale MS
AU$205
1 Nov - 2 Nov
includes taxes & fees
8.2/10 Very good! (411 reviews)
Hampton Inn Clarksdale
Travelers Hotel

Travelers Hotel

212 3rd St Clarksdale MS
AU$233
4 Oct - 5 Oct
includes taxes & fees
Travelers Hotel
High Cotton Condos

High Cotton Condos

249 Delta Ave Clarksdale MS
Get rates
8.8/10 Excellent! (6 reviews)
High Cotton Condos

Frequently asked questions

What is the best area to stay in Lyon?
The best area to stay in Lyon, Mississippi, is near the intersection of Highway 61 and Highway 322, particularly around the few accommodations available in the town itself.This area is the most convenient for visitors as it's where you'll find the limited lodging options and easy access to the main roads. Lyon is a very small town, so the "best" area is essentially the most central and accessible part.For solo travellers or couples passing through, staying directly in Lyon offers a practical stop.
When is the best time to go to Lyon?
The best time to visit Lyon, Mississippi, is during the spring (April to May) and autumn (September to October) months.These periods offer pleasant weather, with mild temperatures and less humidity, making it ideal for exploring the area comfortably. You'll find it's a great time for outdoor activities without the intense heat of summer or the cooler temperatures of winter.Spring brings blooming flora and a generally uplifting atmosphere, great for those who enjoy strolls and appreciating natural beauty.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if cancelled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Lyon.
How can I save on a hotel booking in Lyon with Expedia?
One Key™—Expedia's free travel rewards program—gives you instant access to discounts with Member Prices on Lyon hotels. Plus, you'll earn OneKeyCash™* on eligible bookings to use on future trips. Booking an Expedia hotel and flight package is another great way to save, where bundling can result in significant savings. *Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
How much is the nightly rate for a hotel in Lyon?
Prices for hotels in Lyon often vary, but you can find a great deal from AU$121 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for our cheapest rates.

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