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Our top choices for Lyon hotels

1. Hampton Inn Clarksdale

Hampton Inn Clarksdale
2.5 star property
Clarksdale
8.4 out of 10, Very good, (421 reviews)
"Was perfect for our stay."
United States
Tami
The price is AU$210
includes taxes & fees
22 Nov - 23 Nov
Hampton Inn Clarksdale

2. Travelers Hotel

Travelers Hotel
2.5 star property
Clarksdale
9.8 out of 10, Exceptional, (330 reviews)
"Enjoyed our stay"
Australia
Daryl
The price is AU$224
includes taxes & fees
16 Dec - 17 Dec
Travelers Hotel

3. Quality Inn Clarksdale

Quality Inn Clarksdale
2.5 star property
Clarksdale
7.2 out of 10, Good, (801 reviews)
"The staff was top notch, way to go ladies!"
United States
Blu
The price is AU$126
includes taxes & fees
18 Nov - 19 Nov
Quality Inn Clarksdale

4. Americas Best Value Inn & Suites Clarksdale

Americas Best Value Inn & Suites Clarksdale
2.5 star property
Clarksdale
6.0 out of 10, (440 reviews)
"Friendly staff , helped me with everything"
United States
Kydesia
The price is AU$129
includes taxes & fees
16 Nov - 17 Nov
Americas Best Value Inn & Suites Clarksdale

5. Auberge Clarksdale Blues Hostel

Auberge Clarksdale Blues Hostel
2.0 star property
Clarksdale
9.6 out of 10, Exceptional, (112 reviews)
"Communication was excellent and the location is perfect."
United States
Jacqueline
The price is AU$171
includes taxes & fees
16 Nov - 17 Nov
Auberge Clarksdale Blues Hostel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

What is the best area to stay in Lyon?
The best area to stay in Lyon, Mississippi, is near the intersection of Highway 61 and Highway 322, particularly around the few accommodations available in the town itself.

This area is the most convenient for visitors as it's where you'll find the limited lodging options and easy access to the main roads. Lyon is a very small town, so the "best" area is essentially the most central and accessible part.

For solo travellers or couples passing through, staying directly in Lyon offers a practical stop.
When is the best time to go to Lyon?
The best time to visit Lyon, Mississippi, is during the spring (April to May) and autumn (September to October) months.

These periods offer pleasant weather, with mild temperatures and less humidity, making it ideal for exploring the area comfortably. You'll find it's a great time for outdoor activities without the intense heat of summer or the cooler temperatures of winter.

Spring brings blooming flora and a generally uplifting atmosphere, great for those who enjoy strolls and appreciating natural beauty.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if cancelled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Lyon.
How can I save on a hotel booking in Lyon with Expedia?
One Key™—Expedia's free travel rewards program—gives you instant access to discounts with Member Prices on Lyon hotels. Plus, you'll earn OneKeyCash™* on eligible bookings to use on future trips. Booking an Expedia hotel and flight package is another great way to save, where bundling can result in significant savings. *Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
How much is the nightly rate for a hotel in Lyon?
Prices for hotels in Lyon often vary, but you can find a great deal from AU$126 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for our cheapest rates.