Spa Hotels & Resorts in Key Largo from AU$448

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Check availability on Key Largo Spa Hotels

Our top choices for Key Largo hotels with a spa

Body treatments, aromatherapy, hot stone massages, deep-tissue massages
Reefhouse Resort & Marina

Reefhouse Resort & Marina

Reefhouse Resort & Marina
3.5 star property
Key Largo
9.2 out of 10, Wonderful, (1335)
"Nice hotel with great staff."
United States
David
The price is AU$448
includes taxes & fees
15 Dec - 16 Dec
Reefhouse Resort & Marina
Sauna, hot tub, steam room, body treatments, hot stone massages
Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection
4.5 star property
Rock Harbor
8.8 out of 10, Excellent, (1000)
"Beautiful location, great views, very clean property, room was great (great bed), friendly staff."
United States
Scott
The price is AU$529
includes taxes & fees
17 Dec - 18 Dec
Playa Largo Resort & Spa, Autograph Collection
In-room dining
Premium Floating Bungalow by Stay Ombi

Premium Floating Bungalow by Stay Ombi

Premium Floating Bungalow by Stay Ombi
3.5 star property
Key Largo
The price is AU$2,134
includes taxes & fees
4 Jan - 5 Jan 2026
Premium Floating Bungalow by Stay Ombi
Exterior
Kona Kai Resort and Gallery - Adults Only

Kona Kai Resort and Gallery - Adults Only

Kona Kai Resort and Gallery - Adults Only
2.5 star property
Rock Harbor
9.8 out of 10, Exceptional, (293)
"The Kona Kai Resort was perfect for us. We especially appreciated the small resort with quiet spaces to relax, read and admire the view. "
United States
Bastianella
Kona Kai Resort and Gallery - Adults Only
Couples treatment room(s), sauna, steam room, body treatments
Cheeca Lodge & Spa

Cheeca Lodge & Spa

Cheeca Lodge & Spa
5.0 star property
Matecumbe
9.2 out of 10, Wonderful, (1270)
"It was awesome, great service, staff members are helpful, clean and tidy room with excellent views!"
United States
Sami
The price is AU$459
includes taxes & fees
16 Dec - 17 Dec
Cheeca Lodge & Spa
Massages
The Islands of Islamorada

The Islands of Islamorada

The Islands of Islamorada
4.0 star property
Matecumbe
9.8 out of 10, Exceptional, (69)
"Great for family vacation with kids. love it"
United States
Dixania
The price is AU$1,098
includes taxes & fees
15 Dec - 16 Dec
The Islands of Islamorada
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Key Largo Hotel Reviews

Amoray Dive Resort

Amoray Dive Resort

10/10 Excellent
"Was in a town home and it had plenty of AC and the full kitchen was great. The teflon pans are a bit destroyed but we made it work. Great warm pool, wonderful water side sitting area with great sunsets. We had some high winds so our dive was delayed a couple of days but they got us rescheduled and the crew was great!. There are lots of cute small jellies in the water around so look out if you decide to go for a swim and not in the pool. "
Charles 3-night trip
Posted 4 days ago
Amoray Dive Resort

Frequently asked questions

Looking for a spa hotel in Key Largo?
Forget the stress of everyday life and book yourself a hotel with a spa. Travellers love the sunsets in Key Largo. Discover the coral reefs and seafood restaurants during your stay. Hotels with spas are the perfect way to break out of your daily routine and add a layer of luxury to your stay.
What is the best spa hotel in Key Largo?
Playa Largo Resort & Spa, Autograph Collection is a top beach spa hotel featuring 3 restaurants, a 24-hour fitness centre, a hair salon and a bar. Treat yourself to a facial, body scrub or Swedish massage at the on-site spa. Another popular spa hotel in Key Largo is Reefhouse Resort & Marina.
How many spa hotels will I find in Key Largo?
Among Expedia's 1308 accommodation options in Key Largo, there are 2 spa hotels.
What's there to see and do in Key Largo?
Enjoy Key Largo and visit Everglades National Park, Jimmy Johnson's Big Chill and Jacob's Aquatic Center. If you have a bit of extra time while you're in the area, you might want to check out Bluefin Rock Harbor Marina and John Pennekamp Coral Reef State Park.
What is a Key Largo spa hotel?
Spa hotels in Key Largo provide lodging and have an on-site spa offering services such as facials and body treatments. Some also offer in-room treatments. Spa hotels are a must if you want to give yourself an extra treat while on holiday.