Keowee Plantation Hotels, Seneca

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
31 Dec - 1 Jan
Tomorrow
1 Jan - 2 Jan
This weekend
2 Jan - 4 Jan
Next weekend
9 Jan - 11 Jan

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Keowee Plantation hotels

Aerial view
Lakeside Lodge Clemson

Lakeside Lodge Clemson

Lakeside Lodge Clemson
2.5 star property
10.9 km from Keowee Plantation
9.0 out of 10, Wonderful, (1000)
"Great place to stay. "
United States
Gene
The price is AU$202
includes taxes & fees
1 Jan - 2 Jan 2026
Lakeside Lodge Clemson
Deluxe Room, 2 Queen Beds, Non Smoking
Days Inn by Wyndham Anderson

Days Inn by Wyndham Anderson

Days Inn by Wyndham Anderson
2.0 star property
28.8 km from Keowee Plantation
7.8 out of 10, Good, (1002)
"Very nice we'll stay there again"
United States
Michael
The price is AU$104
includes taxes & fees
4 Jan - 5 Jan 2026
Days Inn by Wyndham Anderson
Reception
Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG

Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG

Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG
2.5 star property
28.1 km from Keowee Plantation
9.0 out of 10, Wonderful, (585)
"It was great. Room was clean and staff was friendly. "
United States
Veronica
The price is AU$144
includes taxes & fees
11 Jan - 12 Jan 2026
Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG
Lobby
Microtel Inn & Suites by Wyndham Anderson/Clemson

Microtel Inn & Suites by Wyndham Anderson/Clemson

Microtel Inn & Suites by Wyndham Anderson/Clemson
2.0 star property
27.9 km from Keowee Plantation
8.2 out of 10, Very good, (1000)
"Clean, convenient location "
United States
Selena
The price is AU$118
includes taxes & fees
4 Jan - 5 Jan 2026
Microtel Inn & Suites by Wyndham Anderson/Clemson
Restaurant
Liberty Hall Bed and Breakfast

Liberty Hall Bed and Breakfast

Liberty Hall Bed and Breakfast
4.0 star property
19.1 km from Keowee Plantation
10.0 out of 10, Exceptional, (78)
"The owners are amazing. Comfy rooms, stellar breakfast and good people. "
United States
Renee
The price is AU$264
includes taxes & fees
2 Jan - 3 Jan 2026
Liberty Hall Bed and Breakfast
Exterior
Hilton Garden Inn Anderson

Hilton Garden Inn Anderson

Hilton Garden Inn Anderson
3.0 star property
28.8 km from Keowee Plantation
9.0 out of 10, Wonderful, (685)
"Rooms were clean, staff were friendly, and we had 2 good night’s sleep."
United States
Sadie
The price is AU$175
includes taxes & fees
7 Jan - 8 Jan 2026
Hilton Garden Inn Anderson
Property amenity
Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center
2.5 star property
14.1 km from Keowee Plantation
8.2 out of 10, Very good, (1000)
"Clean room and staff were great’"
United States
Audrey
The price is AU$154
includes taxes & fees
4 Jan - 5 Jan 2026
Best Western Plus Clemson Hotel & Conference Center
Outdoor pool, open 9:00 AM to 9:00 PM, pool loungers
Fairfield Inn & Suites by Marriott Anderson Clemson

Fairfield Inn & Suites by Marriott Anderson Clemson

Fairfield Inn & Suites by Marriott Anderson Clemson
2.5 star property
28.1 km from Keowee Plantation
9.0 out of 10, Wonderful, (567)
"Clean room staff was verynice!"
United States
Laura Jo
The price is AU$148
includes taxes & fees
8 Jan - 9 Jan 2026
Fairfield Inn & Suites by Marriott Anderson Clemson
Free buffet breakfast
Country Inn & Suites by Radisson, Anderson, SC

Country Inn & Suites by Radisson, Anderson, SC

Country Inn & Suites by Radisson, Anderson, SC
2.5 star property
28.1 km from Keowee Plantation
8.4 out of 10, Very good, (1001)
"Check in staff was very nice & let us in a bit early which was a blessing after being on road "
United States
Lynette
The price is AU$185
includes taxes & fees
7 Jan - 8 Jan 2026
Country Inn & Suites by Radisson, Anderson, SC
Coffee service
Comfort Suites Anderson-Clemson

Comfort Suites Anderson-Clemson

Comfort Suites Anderson-Clemson
2.5 star property
28.4 km from Keowee Plantation
8.4 out of 10, Very good, (1000)
"Clean, staff, convenient location to dining and 85"
United States
Selena
The price is AU$178
includes taxes & fees
4 Jan - 5 Jan 2026
Comfort Suites Anderson-Clemson
Reception hall
The Inn at Patrick Square

The Inn at Patrick Square

The Inn at Patrick Square
3.5 star property
17.6 km from Keowee Plantation
9.8 out of 10, Exceptional, (786)
"Everything was clean staff was courteous and accommodating. "
United States
Stewart
The price is AU$247
includes taxes & fees
4 Jan - 5 Jan 2026
The Inn at Patrick Square
Lobby
Comfort Inn & Suites Clemson - University Area

Comfort Inn & Suites Clemson - University Area

Comfort Inn & Suites Clemson - University Area
2.5 star property
14 km from Keowee Plantation
8.2 out of 10, Very good, (1000)
"Great area behind the hotel to walk my dog!!"
United States
Connie
The price is AU$170
includes taxes & fees
11 Jan - 12 Jan 2026
Comfort Inn & Suites Clemson - University Area
Free daily on-the-go breakfast
Quality Inn Seneca Clemson Area US-123

Quality Inn Seneca Clemson Area US-123

Quality Inn Seneca Clemson Area US-123
2.5 star property
Downtown, 2.8 km from Keowee Plantation
8.0 out of 10, Very good, (666)
"Good available parking. Room clean. Breakfast was minimal, but good. The tub was slippery and needed a mat. I almost fell a couple of times. I would stay here again."
United States
Denise
The price is AU$130
includes taxes & fees
11 Jan - 12 Jan 2026
Quality Inn Seneca Clemson Area US-123
Lobby
Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson
2.5 star property
10.6 km from Keowee Plantation
9.2 out of 10, Wonderful, (800)
"Staff is amazing, hotel and amenities are great. "
United States
Shannon
The price is AU$166
includes taxes & fees
11 Jan - 12 Jan 2026
Tru by Hilton Seneca Clemson
Outdoor pool
Baymont by Wyndham Anderson Clemson

Baymont by Wyndham Anderson Clemson

Baymont by Wyndham Anderson Clemson
2.5 star property
28.1 km from Keowee Plantation
7.0 out of 10, Good, (847)
"Well lit parking and safe area around the hotel"
United States
Gregory
The price is AU$99
includes taxes & fees
12 Jan - 13 Jan 2026
Baymont by Wyndham Anderson Clemson
Exterior
Holiday Inn Express & Suites Clemson by IHG

Holiday Inn Express & Suites Clemson by IHG

Holiday Inn Express & Suites Clemson by IHG
2.5 star property
14.7 km from Keowee Plantation
8.8 out of 10, Excellent, (950)
"Had a great stay at this hotel. Conveniently located near restaurants. "
United States
Kelly
The price is AU$196
includes taxes & fees
9 Jan - 10 Jan 2026
Holiday Inn Express & Suites Clemson by IHG
Lobby lounge
Inn @ Clemson

Inn @ Clemson

Inn @ Clemson
2.5 star property
13.9 km from Keowee Plantation
8.0 out of 10, Very good, (1002)
"Staff and hotel was amazing "
United States
Keren
Inn @ Clemson
Balcony
Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area
2.5 star property
1.4 km from Keowee Plantation
9.4 out of 10, Exceptional, (205)
"Nice hotel by the lake"
United States
Mike
The price is AU$204
includes taxes & fees
1 Jan - 2 Jan 2026
Fairfield Inn & Suites Seneca Clemson Univ Area
Fireplace
Courtyard Marriott Clemson

Courtyard Marriott Clemson

Courtyard Marriott Clemson
3.0 star property
15.2 km from Keowee Plantation
9.0 out of 10, Wonderful, (524)
"Overall, great stay!"
United States
Lynn
The price is AU$196
includes taxes & fees
5 Jan - 6 Jan 2026
Courtyard Marriott Clemson
In-room safe, blackout curtains, soundproofing, iron/ironing board
The Shepherd Hotel Downtown Clemson

The Shepherd Hotel Downtown Clemson

The Shepherd Hotel Downtown Clemson
4.0 star property
13 km from Keowee Plantation
9.8 out of 10, Exceptional, (745)
"Staff was amazing and our room was clean and comfortable. "
United States
Amanda R
The price is AU$294
includes taxes & fees
1 Jan - 2 Jan 2026
The Shepherd Hotel Downtown Clemson
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Our guide on where to stay in Keowee Plantation

Find the best Keowee Plantation areas for the activities you enjoy most.

Serenity Bay

When in Serenity Bay, you can plan a visit to Keowee Key Golf Course and Lake Keowee, some noteworthy sights in the nearby area.

Downtown

If you're spending some time in Downtown, Seneca Historic District and Oconee County Library Seneca Branch are top sights worth seeing.

Pine Ridge Point

If you're looking for some top things to see and do in Pine Ridge Point and surrounding area, you can visit Lake Keowee and Keowee Key Golf Course.

Indian Oaks

While Indian Oaks may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Keowee Reservoir and Oconee County Library Seneca Branch.

Top Keowee Plantation Hotel Reviews

Woodspring Suites Anderson North I-85

Woodspring Suites Anderson North I-85

10/10 Excellent
"Very Clean!"
Joseph 1-night trip
Posted 9 days ago
Woodspring Suites Anderson North I-85

Frequently asked questions

What's it like in Keowee Plantation?
You'll be sure to have fun exploring Seneca's Keowee Plantation neighbourhood. Consider a visit to Lake Keowee as part of your Keowee Plantation travel plans.
If I need to cancel my hotel reservation in Keowee Plantation, will I receive a refund?
Yes! Most hotel reservations are fully refundable as long as you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your arrival date. If you have a reservation that's non-refundable, you might be able to cancel it and get a refund within a 24-hour period of your booking. Add dates, click "Search", then filter by "fully refundable" to review the top deals on offer in Keowee Plantation.
What is there to do around this Seneca neighbourhood?
Lake Keowee is an attraction you might want to check out while you're in Keowee Plantation. Golden Corner Plaza and Applewood Shopping Center are also worth a visit when you're out sightseeing in Seneca.