Top Hotels Near Isle Casino Cape Girardeau in Cape Girardeau from AU$96

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27 Dec - 28 Dec
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28 Dec - 29 Dec
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2 Jan - 4 Jan
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Our top choices for Isle Casino Cape Girardeau hotels

Standard Room, 1 Queen Bed, Non Smoking, Garden View
Rockwood Inn

Rockwood Inn

Rockwood Inn
2.0 star property
1.3 km from Isle Casino Cape Girardeau
10.0 out of 10, Exceptional, (18)
"We came into town for a concert and had a blast! The hotel was super comfy, and the staff were friendly. The rooms were very clean and the decor was beautiful! "
United States
Vanessa
The price is AU$232
includes taxes & fees
29 Dec - 30 Dec
Rockwood Inn
Lobby
Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown
3.0 star property
0.7 km from Isle Casino Cape Girardeau
9.6 out of 10, Exceptional, (469)
"Very nice hotel within walking distance to many good restaurants "
United States
Vicky
The price is AU$211
includes taxes & fees
11 Jan - 12 Jan 2026
Courtyard by Marriott Cape Girardeau Downtown
Lobby sitting area
The Riverview

The Riverview

The Riverview
4.0 star property
0.2 km from Isle Casino Cape Girardeau
9.4 out of 10, Exceptional, (477)
"The room was clean and the mattress was extremely comfortable "
United States
Stacy
The price is AU$157
includes taxes & fees
29 Dec - 30 Dec
The Riverview
Desk, free WiFi
Town House Inn Cape Giradreau

Town House Inn Cape Giradreau

Town House Inn Cape Giradreau
2.5 star property
3.1 km from Isle Casino Cape Girardeau
6.0 out of 10, (206)
"Along a main street but not a lot of noise, especially in the rooms. Rooms exit to the outdoors."
United States
Gary
The price is AU$96
includes taxes & fees
4 Jan - 5 Jan 2026
Town House Inn Cape Giradreau
Courtyard
Hampton Inn Cape Girardeau I 55 East

Hampton Inn Cape Girardeau I 55 East

Hampton Inn Cape Girardeau I 55 East
2.5 star property
5.2 km from Isle Casino Cape Girardeau
9.6 out of 10, Exceptional, (785)
"Excellent stay"
United States
Christina
The price is AU$178
includes taxes & fees
4 Jan - 5 Jan 2026
Hampton Inn Cape Girardeau I 55 East
Lobby
Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
3.0 star property
5.5 km from Isle Casino Cape Girardeau
9.6 out of 10, Exceptional, (1004)
"Great place and staff, very accommodating!"
United States
Megan
The price is AU$151
includes taxes & fees
1 Jan - 2 Jan 2026
Drury Plaza Hotel Cape Girardeau Conference Center
Exterior
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
2.5 star property
5.3 km from Isle Casino Cape Girardeau
9.4 out of 10, Exceptional, (1000)
"We like to stay at this hotel on our way to New Orleans and on our return trip to Wisconsin. It is convenient, clean, breakfast options are excellent and the 8 pm cookie time is always a hit. Staff are also very friendly. "
United States
Brian
The price is AU$153
includes taxes & fees
4 Jan - 5 Jan 2026
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Lobby
Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau
2.5 star property
5.4 km from Isle Casino Cape Girardeau
9.4 out of 10, Exceptional, (143)
"Nice hotel, clean and comfortable "
United States
Laura
The price is AU$148
includes taxes & fees
4 Jan - 5 Jan 2026
Fairfield Inn & Suites by Marriott Cape Girardeau
Business centre
Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau
3.0 star property
5.7 km from Isle Casino Cape Girardeau
9.4 out of 10, Exceptional, (1000)
"Very friendly staff and great breakfast"
United States
Ray
The price is AU$151
includes taxes & fees
1 Jan - 2 Jan 2026
Drury Inn & Suites Cape Girardeau
Room, 2 Queen Beds
Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau
2.5 star property
8.3 km from Isle Casino Cape Girardeau
9.6 out of 10, Exceptional, (104)
"It was a nice stay"
United States
Douglas
The price is AU$151
includes taxes & fees
4 Jan - 5 Jan 2026
Tru By Hilton Cape Girardeau
Lobby
Pear Tree Inn Cape Girardeau Near the Medical Center

Pear Tree Inn Cape Girardeau Near the Medical Center

Pear Tree Inn Cape Girardeau Near the Medical Center
2.5 star property
5.2 km from Isle Casino Cape Girardeau
9.0 out of 10, Wonderful, (1003)
"Nice place for a stay at a reasonable price."
United States
Arthur
The price is AU$118
includes taxes & fees
1 Jan - 2 Jan 2026
Pear Tree Inn Cape Girardeau Near the Medical Center
Property amenity
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
3.0 star property
9.5 km from Isle Casino Cape Girardeau
9.0 out of 10, Wonderful, (677)
"Great place "
United States
GUY
The price is AU$136
includes taxes & fees
7 Jan - 8 Jan 2026
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Lobby
Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO
3.0 star property
17 km from Isle Casino Cape Girardeau
9.6 out of 10, Exceptional, (1003)
"Breakfast was great- staff was welcoming. Will stay there again."
United States
Laura
The price is AU$131
includes taxes & fees
29 Dec - 30 Dec
Drury Inn & Suites Jackson MO
Exterior
Candlewood Suites Cape Girardeau by IHG

Candlewood Suites Cape Girardeau by IHG

Candlewood Suites Cape Girardeau by IHG
2.5 star property
5.4 km from Isle Casino Cape Girardeau
8.2 out of 10, Very good, (886)
"Room was clean and spacious."
United States
George
The price is AU$126
includes taxes & fees
25 Jan - 26 Jan 2026
Candlewood Suites Cape Girardeau by IHG
Lobby
Comfort Suites Jackson-Cape Girardeau

Comfort Suites Jackson-Cape Girardeau

Comfort Suites Jackson-Cape Girardeau
2.5 star property
9.5 km from Isle Casino Cape Girardeau
8.2 out of 10, Very good, (740)
"Room was clean and affordable for one night. The morning person could have been more attentive to me being there for breakfast. No greeting at all and sat on her phone. I was the only one down in the breakfast area. Be more aware of her surroundings while working alone. "
United States
Lori
The price is AU$129
includes taxes & fees
4 Jan - 5 Jan 2026
Comfort Suites Jackson-Cape Girardeau
Lobby
Quality Inn Cape Girardeau North

Quality Inn Cape Girardeau North

Quality Inn Cape Girardeau North
2.5 star property
6.2 km from Isle Casino Cape Girardeau
7.2 out of 10, Good, (686)
"Overall was wonderful customer service and breakfast"
United States
Stephanie
The price is AU$99
includes taxes & fees
8 Jan - 9 Jan 2026
Quality Inn Cape Girardeau North
Economy Single Room, 1 Queen Bed, Kitchenette
Town House Inn

Town House Inn

Town House Inn
2.5 star property
14.6 km from Isle Casino Cape Girardeau
7.6 out of 10, Good, (426)
"The staff member Tim was very friendly and nice. "
United States
Julie
The price is AU$103
includes taxes & fees
28 Jan - 29 Jan 2026
Town House Inn
Lobby
Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West
2.5 star property
5.6 km from Isle Casino Cape Girardeau
9.0 out of 10, Wonderful, (1001)
"Great stay"
United States
Heather
The price is AU$118
includes taxes & fees
1 Jan - 2 Jan 2026
Pear Tree Inn Cape Girardeau West
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Isle Casino Cape Girardeau Hotel Reviews

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

10/10 Excellent
"Always a pleasant stay. Friendly staff, clean rooms, accessible pool and great food."
Chad 1-night trip
Posted 1 day ago
Drury Plaza Hotel Cape Girardeau Conference Center

Hotels near other Isle Casino Cape Girardeau attractions

Panorama of Academic Hall, Southeast Missouri State University

Southeast Missouri State University

4.4/5 (137 reviews)
Take a campus tour or just explore the area of Southeast Missouri State University during your trip to Cape Girardeau. While in this family-friendly area, you can savour the top-notch restaurants.
See properties
View of the Christopher S. Bond Bridge over Missouri River in Kansas City, from the riverfront park

Riverfront Bridge Park

4.4/5 (74 reviews)
Riverfront Bridge Park is just one of the places to see in Cape Girardeau, so why not enjoy the other things to explore during your travels? While in this family-friendly area, you can savour the top-notch restaurants.
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Frequently asked questions

What's the area like around Isle Casino Cape Girardeau?
Isle Casino Cape Girardeau is located in a family-friendly area of Cape Girardeau known for its array of dining options. If you're looking for a convenient place to stay, take a look at the 27 hotels and other accommodation options you'll find within a mile.
What's the best hotel to stay near Isle Casino Cape Girardeau?
Adjacent to Isle Casino Cape Girardeau, The Riverview is one of the top choices for your stay based on our traveller data, and this hotel offers a casino and 2 restaurants. Another good choice is Courtyard by Marriott Cape Girardeau Downtown, located just 0.4 mi (0.7 km) away.
How many hotels should I expect to find close to Isle Casino Cape Girardeau?
Expedia has 27 hotels and other accommodation options within a mile from Isle Casino Cape Girardeau.
If I need to cancel the hotel reservation for my stay near Isle Casino Cape Girardeau, will I receive a refund?
Yes! You'll find that most hotel room reservations are fully refundable if cancelled prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If your reservation is non-refundable, you may still be able to cancel and get a refund within 24 hours of booking. Enter your dates, click on "Search", then you can use the "fully refundable" filter to review the top deals on offer near Isle Casino Cape Girardeau.
What can I see and do near Isle Casino Cape Girardeau?
You might spend a leisurely day outdoors at Fort D Historic Site and Cape Rock Park. Create some family memories at Cape Splash Family Aquatic Center and Cape Girardeau Conservation Nature Center. If you're looking for something to do, plan a visit to Show Me Center, eDen Spa & Salon and Devil's Island Wildlife Management Area while you're in the area.