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Our top choices for Guadalupe hotels

Mucumbli Hotel

Mucumbli Hotel
3.0 star property
Neves
9.4 out of 10, Exceptional, (26)
"A bit rustier than i expected. Beds were SUPER sq "
Norway
Morten
The price is AU$220
includes taxes & fees
16 Jan - 17 Jan 2026
Mucumbli Hotel

Omali São Tomé – Principe Collection

Omali São Tomé – Principe Collection
4.0 star property
São Tomé
9.4 out of 10, Exceptional, (62)
"It’s a great resort, with friendly staff who "
United Kingdom
Kim
The price is AU$339
includes taxes & fees
6 Jan - 7 Jan 2026
Omali São Tomé – Principe Collection

Praia Accommodation

Praia Accommodation
3.0 star property
São Tomé
7.2 out of 10, Good, (17)
"Great place to stay "
United States
Daniel
The price is AU$219
includes taxes & fees
29 Dec - 30 Dec
Praia Accommodation

Hotel Kenito

Hotel Kenito
2.5 star property
São Tomé
10.0 out of 10, Exceptional, (3)
"Exceptional"
United States
Nii Tetteh
The price is AU$147
includes taxes & fees
28 Jan - 29 Jan 2026
Hotel Kenito

CAMPISMO PRAIA GRANDE

CAMPISMO PRAIA GRANDE
1.0 star property
Malanza
8.6 out of 10, Excellent, (4)
"A little piece of paradise on an amazing beach. "
United Kingdom
John
The price is AU$87
includes taxes & fees
28 Jan - 29 Jan 2026
CAMPISMO PRAIA GRANDE

SH Boutique Hotel

SH Boutique Hotel
3.5 star property
São Tomé
8.6 out of 10, Excellent, (10)
"Staff were very accommodating "
United States
Simon Peter
SH Boutique Hotel

Pestana São Tomé

Pestana São Tomé
5.0 star property
Vila Maria
8.0 out of 10, Very good, (78)
"Wonderful stay, great staff, easy, relaxing delightful."
Canada
alexander
The price is AU$353
includes taxes & fees
4 Jan - 5 Jan 2026
Pestana São Tomé

Guest House Quinta Natural

Guest House Quinta Natural
3.0 star property
Trindade
10.0 out of 10, Exceptional, (1)
Guest House Quinta Natural

Hotel Praia

Hotel Praia
3.5 star property
São Tomé
7.4 out of 10, Good, (18)
"Solid, basic hotel. "
United States
Jonathan
The price is AU$257
includes taxes & fees
29 Dec - 30 Dec
Hotel Praia

Hotel Central

Hotel Central
3.5 star property
São Tomé
8.2 out of 10, Very good, (24)
"Great value. Great location. Ok breakfast. Overall good value for money"
Norway
Elisabeth
Hotel Central

Casa de Ferias

Casa de Ferias
3.0 star property
São Tomé
8.8 out of 10, Excellent, (6)
"I had a very good time here, got a lot of service and information from the family and in fact almost felt like a family member."
Sweden
Lars Roland
The price is AU$114
includes taxes & fees
29 Dec - 30 Dec
Casa de Ferias

Alojamento Santos Silva

Alojamento Santos Silva
3.0 star property
São Tomé
The price is AU$520
includes taxes & fees
29 Dec - 30 Dec
Alojamento Santos Silva

Pestana Miramar São Tomé

Pestana Miramar São Tomé
3.0 star property
São Tomé
7.2 out of 10, Good, (45)
"Very helpful and accommodating staff"
United States
sandra
The price is AU$257
includes taxes & fees
4 Jan - 5 Jan 2026
Pestana Miramar São Tomé
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about Guadalupe

Head to São Sebastião Museum and Estadio Nacional 12 de Julho—just two of the sights around Guadalupe.

So beautiful beach... Quite difficult to reach, but you have to go...
Photo by Fabrice Récalt
Open Photo by Fabrice Récalt

Top Guadalupe Hotel Reviews

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Frequently asked questions

Where is the best place to stay in Guadalupe?
Based on our traveller data, Residêncial Tamarindos is one of the top choices for your stay. This guest house offers a restaurant and free parking. Two other options for your stay in the area are Pestana São Tomé and Hotel Central. See all available top hotels, or vacation rentals in Guadalupe.
What are some of the best holiday rentals that Guadalupe has to offer?
Alojamento Santos Silva: This holiday home rental outside Guadalupe offers an outdoor pool, a garden and laundry facilities to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include an oven, a microwave and kitchenware. See all vacation rentals in Guadalupe.
If I need to cancel my hotel reservation in Guadalupe, will I receive a refund?
Yes! You'll find that most hotel room reservations are fully refundable as long as you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If your reservation is non-refundable, it might still be possible to cancel it and get a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Guadalupe.
How is it to stay in Guadalupe?
Those travelling to Guadalupe will definitely enjoy the sights to see and things to do. There are 45 hotels and other accommodation options in the surrounding area. Find out more about Guadalupe.
What are the top places to visit in Guadalupe?
Places to visit in the wider area include São Sebastião Museum, Estadio Nacional 12 de Julho and Palácio dos Congressos. You'll also find Pico São Tomé and Coffee Museum in the area. Take a look at what more there is to see and do in Expedia's Guadalupe guide.

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