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Our top choices for Greenville hotels

Holiday Inn Express Greenville by IHG

Holiday Inn Express Greenville by IHG
2.5 star property
Greenville
9.2 out of 10, Wonderful, (646)
"Super clean, friendly staff, excellent breakfast!"
United States
Aimee
The price is AU$213
includes taxes & fees
23 Dec - 24 Dec
Holiday Inn Express Greenville by IHG

Comfort Inn Greenville I-65

Comfort Inn Greenville I-65
2.5 star property
Greenville
8.6 out of 10, Excellent, (849)
"Great spot to stop for quick overnight stay"
United States
Chrie
The price is AU$163
includes taxes & fees
20 Dec - 21 Dec
Comfort Inn Greenville I-65

Quality Inn & Suites Greenville I-65

Quality Inn & Suites Greenville I-65
2.5 star property
Greenville
7.6 out of 10, Good, (47)
"I was just visiting family at the last minute decided to stay, asked family suggested to stay here, very clean, quiet, plenty of parking, great customer service "
United States
Diane
The price is AU$134
includes taxes & fees
13 Jan - 14 Jan 2026
Quality Inn & Suites Greenville I-65

Hampton Inn Greenville

Hampton Inn Greenville
2.5 star property
Greenville
8.6 out of 10, Excellent, (351)
"Everything was clean and comfortable. The staff was nice. And the breakfast was wonderful."
United States
Cheri
The price is AU$167
includes taxes & fees
21 Dec - 22 Dec
Hampton Inn Greenville

Best Western Greenville Inn

Best Western Greenville Inn
2.5 star property
Greenville
8.2 out of 10, Very good, (812)
"Rooms were nice and clean and the desk staff was really nice. "
United States
Michael
The price is AU$130
includes taxes & fees
21 Dec - 22 Dec
Best Western Greenville Inn

Days Inn by Wyndham Greenville

Days Inn by Wyndham Greenville
2.0 star property
Greenville
7.0 out of 10, Good, (176)
"Staff was very nice"
United States
Allison
The price is AU$119
includes taxes & fees
26 Dec - 27 Dec
Days Inn by Wyndham Greenville

The Rutledge Inn

The Rutledge Inn
2.5 star property
Luverne
8.4 out of 10, Very good, (498)
"Great for our needs and price, as a stop over on our way to the beach"
United States
Dana
The price is AU$108
includes taxes & fees
15 Dec - 16 Dec
The Rutledge Inn

Holiday Inn Express Andalusia by IHG

Holiday Inn Express Andalusia by IHG
2.5 star property
Andalusia
9.2 out of 10, Wonderful, (340)
"all was great- very clean- hospitality was kind"
United States
Lisa
The price is AU$249
includes taxes & fees
13 Jan - 14 Jan 2026
Holiday Inn Express Andalusia by IHG

Best Western Andalusia Inn

Best Western Andalusia Inn
2.5 star property
Andalusia
8.8 out of 10, Excellent, (313)
"Good accommodations, quiet, we stop here every year on the way to the beach "
United States
Anonymous traveller
The price is AU$201
includes taxes & fees
1 Jan - 2 Jan 2026
Best Western Andalusia Inn

Days Inn by Wyndham Andalusia

Days Inn by Wyndham Andalusia
2.0 star property
Andalusia
7.2 out of 10, Good, (341)
"It was just an overnight stay but Amanda at the front desk was graceous and helpful "
United States
Elaine C
The price is AU$112
includes taxes & fees
5 Jan - 6 Jan 2026
Days Inn by Wyndham Andalusia

Econo Lodge Andalusia

Econo Lodge Andalusia
2.0 star property
Andalusia
7.2 out of 10, Good, (240)
"Clean rooms, staff was friendly, quiet stay"
United States
Tim
The price is AU$126
includes taxes & fees
14 Jan - 15 Jan 2026
Econo Lodge Andalusia

Quality Inn Andalusia

Quality Inn Andalusia
2.5 star property
Andalusia
6.2 out of 10, (216)
"Very nice and restful stay. "
United States
Patricia
The price is AU$138
includes taxes & fees
7 Jan - 8 Jan 2026
Quality Inn Andalusia
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Greenville attractions

Learn more about Greenville

Stroll through the historic city centre where local shops and the Ritz Theatre offer small-town charm with surprising character. Outdoor enthusiasts can explore Sherling Lake Park's fishing spots and hiking trails, especially beautiful during spring's Camellia Festival.

First Baptist Church, Greenville, Mississippi

Top Greenville Hotel Reviews

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Frequently asked questions

What's the best place to stay in Greenville?
Holiday Inn Express Greenville by IHG is ranked highly by Expedia customers. This hotel offers free breakfast and an outdoor pool. Reviews from our site also recommend Hampton Inn Greenville and Comfort Inn Greenville I-65 as top choices for your stay. See all available top hotels, or vacation rentals in Greenville.
What are some of the best holiday rentals that Greenville has to offer?
Waterfront Deck! Couple's Retreat on Point A Lake: This holiday home rental outside of Greenville is located on a lake, and has a patio, a garden and a BBQ to put you at ease in your new surroundings. Kitchen amenities include a dishwasher, a fridge and a stovetop. See all vacation rentals in Greenville.
If I need to cancel my hotel reservation in Greenville, will I receive a refund?
Yes, the majority of hotel bookings are refundable if you cancel before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you have a non-refundable reservation, you might be able to still cancel and receive a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Greenville.
What is the top LGBTQ-friendly accommodation in Greenville?
Hampton Inn Greenville is a top LGBTQ-friendly hotel, and features free breakfast and free WiFi. Holiday Inn Express Greenville by IHG is another good option for your stay. See all available hotels listed as LGBTQ-friendly in Greenville.
What's the best dog-friendly place to stay in Greenville?
Comfort Inn Greenville I-65 is a top hotel for people travelling with their pets, and offers a seasonal outdoor pool and free newspapers for its human guests. Two other good options for you and your pet include Best Western Greenville Inn and Days Inn by Wyndham Greenville. See more pet-friendly hotel accommodations in Greenville.
What are some accommodation options with pools in Greenville?
Hampton Inn Greenville is a top hotel with a pool, free buffet breakfast and free WiFi. View all hotels with pools in Greenville.
How is it to stay in Greenville?
Visitors to Greenville will definitely enjoy the restaurants. Tourists can also enjoy the city's golf courses and entertainment choices. In Greenville, there are 7 hotels and other accommodation options to choose from. Find out more about Greenville.
What is there to see in Greenville?
Landmarks like East Commerce Street Historic District, Commerce Street Residential Historic District and Fort Dale-College Street Historic District might be worth a visit. The picturesque setting of Beeland Park and Washington Street Playground exemplify the area's natural beauty. A couple of additional sights to add to your itinerary are Greenville Country Club and Cambrian Ridge. Take a look at what more there is to see and do in Expedia's Greenville guide.
What's the seasonal weather in Greenville?
The hottest months are usually July and August, with an average temperature of 26°C, while the coldest months are January and February, with an average of 11°C. Average annual precipitation for Greenville is 1468 mm.

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