Luxury Hotels & Resorts in Florence from AU$141

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Check availability on Florence Luxury Hotels

Tonight
28 Dec - 29 Dec
Tomorrow
29 Dec - 30 Dec
Next weekend
2 Jan - 4 Jan
In two weeks
9 Jan - 11 Jan
No exact matches found, but these alternatives could be just right

Recommended hotels in Florence

Fridge, microwave, oven, stovetop
Stunning historic home w/ large rooms. Close to attractions. Kid & pet friendly!

Stunning historic home w/ large rooms. Close to attractions. Kid & pet friendly!

Stunning historic home w/ large rooms. Close to attractions. Kid & pet friendly!
Sellers
10.0 out of 10, Exceptional, (18)
"Great stay for our event. "
United States
Chris W.
The price is AU$975
includes taxes & fees
29 Dec - 30 Dec
Stunning historic home w/ large rooms. Close to attractions. Kid & pet friendly!
Exterior detail
Perfect Stop • Near I-95, Downtown & Civic Center and Darlington

Perfect Stop • Near I-95, Downtown & Civic Center and Darlington

Perfect Stop • Near I-95, Downtown & Civic Center and Darlington
2.0 star property
Florence
10.0 out of 10, Exceptional, (2)
"It was perfect! And the host was the best everrrr I loved every second I will be returning! "
United States
Kimesha C.
The price is AU$408
includes taxes & fees
11 Jan - 12 Jan 2026
Perfect Stop • Near I-95, Downtown & Civic Center and Darlington
Fridge, microwave, oven, stovetop
Take a rest in Florence .Ideal for i95 traveler and Florence Center and Buc-ee's

Take a rest in Florence .Ideal for i95 traveler and Florence Center and Buc-ee's

Take a rest in Florence .Ideal for i95 traveler and Florence Center and Buc-ee's
Florence
10.0 out of 10, Exceptional, (37)
"I would definitely stay again! Great location."
United States
LaDara D.
The price is AU$396
includes taxes & fees
11 Jan - 12 Jan 2026
Take a rest in Florence .Ideal for i95 traveler and Florence Center and Buc-ee's
Interior
Secret SC Cabin on 100 acres Hot Tub Large Pond

Secret SC Cabin on 100 acres Hot Tub Large Pond

Secret SC Cabin on 100 acres Hot Tub Large Pond
Marion
9.6 out of 10, Exceptional, (176)
"We WILL be back to this cute little cabin! It had everything. Only thing better would be more fish in the pond lol thanks for having us!"
United States
Kimberly L.
The price is AU$696
includes taxes & fees
29 Dec - 30 Dec
Secret SC Cabin on 100 acres Hot Tub Large Pond
Private kitchen
Country Oasis: 25-30min from Hartsville, Darlington, Camden, Sumter and Florence

Country Oasis: 25-30min from Hartsville, Darlington, Camden, Sumter and Florence

Country Oasis: 25-30min from Hartsville, Darlington, Camden, Sumter and Florence
Bishopville
The price is AU$450
includes taxes & fees
29 Dec - 30 Dec
Country Oasis: 25-30min from Hartsville, Darlington, Camden, Sumter and Florence
Exterior
Located in Marion. Only 1 hour from Myrtle Beach, 35 minutes from Florence!

Located in Marion. Only 1 hour from Myrtle Beach, 35 minutes from Florence!

Located in Marion. Only 1 hour from Myrtle Beach, 35 minutes from Florence!
Marion
9.0 out of 10, Wonderful, (6)
"It was a great place. "
United States
Cindy N.
The price is AU$885
includes taxes & fees
29 Dec - 30 Dec
Located in Marion. Only 1 hour from Myrtle Beach, 35 minutes from Florence!
Rooftop terrace
The Mantissa Hotel

The Mantissa Hotel

The Mantissa Hotel
3.0 star property
Hartsville
9.2 out of 10, Wonderful, (271)
"Very nice spacious rooms friendly staff"
United States
Duane
The price is AU$249
includes taxes & fees
6 Jan - 7 Jan 2026
The Mantissa Hotel
Fridge, microwave, oven, stovetop
Lovely upscale 3-bedroom Loft apartment downtown Marion

Lovely upscale 3-bedroom Loft apartment downtown Marion

Lovely upscale 3-bedroom Loft apartment downtown Marion
2.0 star property
Marion
The price is AU$331
includes taxes & fees
30 Dec - 31 Dec
Lovely upscale 3-bedroom Loft apartment downtown Marion
Exterior
Staybridge Suites Florence - Civic Center by IHG

Staybridge Suites Florence - Civic Center by IHG

Staybridge Suites Florence - Civic Center by IHG
3.0 star property
Florence
9.4 out of 10, Exceptional, (933)
"Great front desk Room was spotless "
United States
Lawrence
The price is AU$225
includes taxes & fees
25 Jan - 26 Jan 2026
Staybridge Suites Florence - Civic Center by IHG
Bar (on property)
Hotel Florence, Tapestry Collection by Hilton

Hotel Florence, Tapestry Collection by Hilton

Hotel Florence, Tapestry Collection by Hilton
3.0 star property
Florence
8.8 out of 10, Excellent, (606)
"Special place. Great staff with an outstanding restaurant "
United States
John D
The price is AU$217
includes taxes & fees
8 Jan - 9 Jan 2026
Hotel Florence, Tapestry Collection by Hilton
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Florence Hotel Reviews

Hotel Florence, Tapestry Collection by Hilton

Hotel Florence, Tapestry Collection by Hilton

10/10 Excellent
"Very nice facility; lots of character. Convenient parking. Good breakfast. Very pleasant staff. Would definitely return. "
Holt 1-night trip
Posted 5 days ago
Hotel Florence, Tapestry Collection by Hilton
Days Inn by Wyndham Florence Near Civic Center

Days Inn by Wyndham Florence Near Civic Center

10/10 Excellent
"Great service besides kids hanging round doors it was alright experience."
Demetrius 1-night trip
Posted 9 days ago
Days Inn by Wyndham Florence Near Civic Center

Frequently asked questions

Are you searching for the perfect hotel for your luxury getaway to Florence?
Expedia can help you get a flight to Florence, SC (FLO-Florence Regional) airport, and then you can select from a variety of places to stay that will deliver the luxury you seek. Amenities are an important consideration when you plan a holiday, so we make it easy to find what you'd like to make your stay special. If you want a posh hotel that has a spa, an indoor pool or luxury bedding, Expedia can assist you in finding the best luxury hotel experience that Florence offers. During your visit, you might want to enjoy the shopping which Florence is known for.
When can I expect good weather in Florence?
Planning for the weather is a good way to make your trip to Florence relaxing and enjoyable, especially when you're splurging. The hottest months are usually July and August, with an average temperature of 26°C, while the coldest months are January and February, with an average of 10°C. Average annual precipitation for Florence is 1366 mm.
What's there to see and do in Florence?
Take in the sights and attractions that Florence offers with a visit to Florence Museum, Florence National Cemetery and Dr. Eddie Floyd Tennis Center. If you have extra time while you're in the area, you might want to stop by Magnolia Mall and Florence Veterans Park.
How can I get around Florence?
It's easier to get around town in style when you know your options. If you want to venture outside the area, hop aboard a train at Florence Station.

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