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Check prices for these dates

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27 Sept - 28 Sept
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28 Sept - 29 Sept
Next weekend
2 Oct - 4 Oct
In two weeks
9 Oct - 11 Oct

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Our top choices for Effingham hotels

A hotel lobby with a reception desk, seating area, and a television screen.
A spacious dining area with multiple tables and chairs, large windows, and a flat-screen TV mounted on the wall.
A hotel room with a sectional sofa, two ottomans, a bed with a green bedspread, and framed pictures on the wall.
A hotel room with a bed, a sofa, an ottoman, and a lamp.

1. Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area
Florence
United States
Mila
AU$161
includes taxes & fees
18 Oct - 19 Oct
Comfort Inn & Suites Florence Center Area
A rooftop terrace with outdoor seating, including sofas and chairs, and a round table.
A modern lounge area with brick walls, large windows, and contemporary furniture.
A multi-story hotel with a modern facade, featuring a prominent 'Hyatt Place' sign on the right.
A modern bar area with a long counter, multiple bar stools, and a variety of bottles and glasses.

2. Hyatt Place Florence Downtown

Hyatt Place Florence Downtown
Florence
United States
Ivette
AU$175
includes taxes & fees
5 Oct - 6 Oct
Hyatt Place Florence Downtown
A hotel room with two beds, a desk with chairs, a television, and artwork on the walls.
A reception area with a wooden desk, a map on the wall, and a sign welcoming visitors to Florence, SC.
A modern lounge area with a sofa, armchairs, and small tables.
A modern kitchen with a coffee station, a dining area with a table and chairs, and a living area with a sofa and a coffee table.

3. TownePlace Suites by Marriott Florence

TownePlace Suites by Marriott Florence
Florence
United Kingdom
William
AU$188
includes taxes & fees
29 Sept - 30 Sept
TownePlace Suites by Marriott Florence
A spacious lobby with a checkered floor, a reception desk, and a chandelier.
A two-story building with a brick facade, a flat roof, and a covered entrance area.
A hotel room with two beds, a desk with a computer, a chair, and a bathroom with a mirror.
A vending area with snack and drink options, including Pepsi refrigerators and a 'MARKET' display with various products.

4. Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence
Florence
United States
HOMERO
AU$103
includes taxes & fees
29 Sept - 30 Sept
Howard Johnson by Wyndham Florence
A hotel entrance with a stone facade, glass doors, and a number '501' above.
A corner market with shelves stocked with snacks and beverages, and two large refrigerators.
A modern living room with a stone fireplace, a blue sofa, a brown leather chair, and a round coffee table.
A hotel reception area with a wooden floor, a reception desk, a seating area with chairs, and a decorative wall with a tree pattern.

5. Fairfield Inn & Suites by Marriott Florence I-20

Fairfield Inn & Suites by Marriott Florence I-20
Florence
United States
Felecia
AU$202
includes taxes & fees
1 Oct - 2 Oct
Fairfield Inn & Suites by Marriott Florence I-20
A hotel lobby with a wooden floor, multiple dining tables, chairs, and a seating area with a sofa.
A lobby with a fireplace, seating area, and a television.
A hotel room with two beds, a desk, a TV, and a window with patterned curtains.
A hotel lobby with a reception desk, seating area, and a welcome mat.

6. Hampton Inn & Suites Florence Center

Hampton Inn & Suites Florence Center
Florence
United States
Bill
AU$175
includes taxes & fees
25 Oct - 26 Oct
Hampton Inn & Suites Florence Center
A modern lobby with a stone column, a fireplace, and yellow rocking chairs around a central table.
An outdoor patio with a wooden table and wicker chairs, a barbecue grill, and a swimming pool in the background.
A modern cafeteria with long wooden tables, green chairs, and yellow accents.
A hotel room with two beds, a desk with a chair, a television, and a window with curtains.

7. Spark by Hilton Florence North I-95, SC

Spark by Hilton Florence North I-95, SC
Florence
United States
Tienia
AU$135
includes taxes & fees
4 Oct - 5 Oct
Spark by Hilton Florence North I-95, SC
A modern living room with a grey sofa, two black hanging chairs, a small table, and a TV mounted on the wall.
A modern kitchen with a patterned backsplash, wooden cabinets, and stainless steel appliances.
A modern hotel with a 'Park Inn by Radisson' sign, featuring a covered entrance, multiple windows, and a parking lot.
A hotel room with a large bed, a desk with a lamp, a chair, a TV, and a window with curtains.

8. Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC
Florence
United States
Windia
AU$142
includes taxes & fees
4 Oct - 5 Oct
Park Inn by Radisson Florence, SC
A hotel room with a bed, a desk, a green sofa, and a painting on the wall.
A spacious lobby with a reception desk, seating area with patterned chairs, and a coffee station.
An indoor swimming pool with lounge chairs and exercise equipment.

9. Home2 Suites by Hilton Florence, SC

Home2 Suites by Hilton Florence, SC
Florence
United States
saleh
AU$177
includes taxes & fees
18 Oct - 19 Oct
Home2 Suites by Hilton Florence, SC
A hotel room with a large bed, a desk with a chair, a television, and a walk-in closet.
A coffee station with two coffee machines and a display of coffee pods and cups.
A modern office space with a long table, two chairs, a desk with a computer, and a wall-mounted colorful artwork.
A Holiday Inn Express & Suites hotel with a covered entrance, palm trees, and a clear sky.

10. Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
Florence
United States
Leigh
AU$201
includes taxes & fees
26 Oct - 27 Oct
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
An outdoor patio area with tables and chairs, a brick wall, and a glass door leading to the interior.
A spacious lobby with a grand staircase, plush seating, and a modern kitchen area.
A spacious living room with hardwood flooring, a staircase, and a large window.
A spacious dining area with multiple tables and chairs, wooden flooring, and a modern chandelier.

11. The Inn at the Crossroads

The Inn at the Crossroads
Lake City
United States
Paige
AU$147
includes taxes & fees
28 Oct - 29 Oct
The Inn at the Crossroads
A modern lobby with seating areas, a reception desk, and a large wall with a decorative panel.
A modern coffee station with a counter, coffee machines, and a seating area with chairs.
An outdoor patio area with tables and chairs, a barbecue grill, and a large window overlooking a fenced area.
A hotel room with a bed, a blue sofa, a brown ottoman, a black office chair, a desk, a lamp, and three framed pictures on the wall.

12. Comfort Suites Florence I-95

Comfort Suites Florence I-95
Florence
United States
Denise
AU$145
includes taxes & fees
18 Oct - 19 Oct
Comfort Suites Florence I-95
An outdoor seating area with a fire pit, cushioned seating, and a pergola with string lights.
A modern lounge area with seating, tables, and a pool table.
A modern hotel restaurant with a breakfast bar, seating area, and a view of the city.
A snack kiosk with a variety of snacks and beverages, a sign for a 24/7 market, and a sign for local items.

13. Tru by Hilton Florence I-95

Tru by Hilton Florence I-95
Florence
United States
Tiffany
AU$164
includes taxes & fees
4 Oct - 5 Oct
Tru by Hilton Florence I-95
A restaurant with brick walls, framed awards, and a bar area.
A spacious kitchen with a dining area, a living room with a fireplace, and a cozy seating arrangement.
A spacious living room with a wooden floor, a ceiling fan, and a dining area with a wooden table and chairs.
An outdoor patio area with a brick wall, a covered seating area with string lights, and potted plants.

14. Hotel Florence, Tapestry Collection by Hilton

Hotel Florence, Tapestry Collection by Hilton
Florence
United States
Ankh
AU$202
includes taxes & fees
22 Oct - 23 Oct
Hotel Florence, Tapestry Collection by Hilton
A spacious lobby with a high ceiling, a central seating area, and a staircase leading to an upper level.
A hotel room with a bed, sofa, TV, and a desk.
A hotel room with a bed, a sofa, a desk, and a TV.
A La Quinta Inn & Suites hotel with a modern facade, a well-lit entrance, and a landscaped garden area.

15. La Quinta Inn & Suites by Wyndham Florence

La Quinta Inn & Suites by Wyndham Florence
Florence
United States
Heather
AU$142
includes taxes & fees
29 Sept - 30 Sept
La Quinta Inn & Suites by Wyndham Florence
A spacious hotel lobby with multiple seating areas, including tables and chairs, a reception desk, and a staircase leading to an upper level.
A corridor with shelves stocked with snacks and a frozen food display.
A lobby with leather sofas, a coffee table, potted plants, and a reception desk.
An indoor swimming pool with clear water, surrounded by a checkered wall pattern, and equipped with multiple seating areas and a lifeguard station.

16. Hampton Inn & Suites Florence-North-I-95

Hampton Inn & Suites Florence-North-I-95
Florence
United States
Michelle
AU$188
includes taxes & fees
4 Oct - 5 Oct
Hampton Inn & Suites Florence-North-I-95
A hotel room with two beds, a wooden headboard, a window with curtains, and a wall-mounted air conditioner.
A modern kitchen with a built-in coffee station, a refrigerator, and a seating area with a patterned rug.
A spacious lobby with a reception desk, a large window display, and a 'market' sign on the wall.

17. SpringHill Suites by Marriott Florence

SpringHill Suites by Marriott Florence
Florence
United States
John
AU$163
includes taxes & fees
18 Oct - 19 Oct
SpringHill Suites by Marriott Florence
A hotel room with a desk, chair, bed, and a yellow sofa.
A hotel with a green roof, a sign reading 'Quality Inn & Suites by Choice Hotels,' and a landscaped front yard with small trees and shrubs.
A reception desk with a stone wall backdrop, a sign reading 'Quality Choice Hotels,' and a reception area with a wooden reception desk and two chairs.
A hotel dining area with wooden tables and chairs, a fireplace, and a television.

18. Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center
Florence
Canada
Noémie
AU$152
includes taxes & fees
25 Oct - 26 Oct
Quality Inn & Suites Florence Civic Center
A modern kitchen with dark wooden cabinets, a stainless steel refrigerator, a microwave, and a coffee maker. There is a dining area with two red chairs and a table.
A hotel room with a bed, a desk, a TV, a refrigerator, and a painting on the wall.
A hotel room with a sofa, a dining table, a coffee maker, a TV, and artwork on the wall.
An outdoor kitchen area with a grill, a pool, and a covered seating area.

19. Staybridge Suites Florence - Civic Center by IHG

Staybridge Suites Florence - Civic Center by IHG
Florence
United States
Tishia
AU$215
includes taxes & fees
11 Oct - 12 Oct
Staybridge Suites Florence - Civic Center by IHG
A spacious lobby with a reception desk, seating area, and large windows.
A Hilton Garden Inn with a large, multi-story building, a covered entrance, and a parking lot.
A spacious lobby with a large fireplace, comfortable seating, and potted plants.
An indoor swimming pool with clear poolside areas, a lifeguard station, and a view of the outside.

20. Hilton Garden Inn Florence

Hilton Garden Inn Florence
Florence
United States
Derrick
AU$182
includes taxes & fees
4 Oct - 5 Oct
Hilton Garden Inn Florence
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Top Effingham Hotel Reviews

Recent Reviews in Effingham

Hampton Inn & Suites Florence Center

Hampton Inn & Suites Florence Center

10/10 Excellent
"I had a bad experience earlier the same day with another hotel canceling my reservation. Everyone at this hotel were wonderful and very helpful."
Connie 1-night trip
Posted less than an hour ago
Hampton Inn & Suites Florence Center
Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC

8/10 Good
"The breakfast was okay for what it was. Room was nice and mostly clean. I believe there was dust and/or mold in the room as it caused sinus issues for both of us staying in the room. Also had one small roach seen on the floor in the bathroom."
Carson 2-night trip
Posted less than an hour ago
Park Inn by Radisson Florence, SC
Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence

10/10 Excellent
"Pretty clean as usual and decent breakfast"
Amayah 1-night trip
Posted less than an hour ago
Howard Johnson by Wyndham Florence
Staybridge Suites Florence - Civic Center by IHG

Staybridge Suites Florence - Civic Center by IHG

8/10 Good
"Staff was amazing and friendly ! Everyone was so helpful and kind ! Very conveniently located off I-95 and lots of restaurant options ."
Kimberly 1-night trip
Posted 1 hour ago
Staybridge Suites Florence - Civic Center by IHG
The Inn at the Crossroads

The Inn at the Crossroads

10/10 Excellent
"It was a great visit. We only stayed 2 nights as we had events in the area to attend."
Henretta 2-night trip
Posted 5 hours ago
The Inn at the Crossroads
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

10/10 Excellent
"The hotel and breakfast was great. Very clean. Not 1 complaint!"
Mark 1-night trip
Posted 6 hours ago
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
Spark by Hilton Florence North I-95, SC

Spark by Hilton Florence North I-95, SC

10/10 Excellent
"I have never been freed soup in the evening. Perfect dinner and it was phenomenal every night!!!"
Cassandra 1-night trip
Posted 1 day ago
Spark by Hilton Florence North I-95, SC
SpringHill Suites by Marriott Florence

SpringHill Suites by Marriott Florence

8/10 Good
"Breakfast was very good, friendly and helpful staff. A bit rundown in some aspects and the pull out trundle mattress was like laying on steel springs. Otherwise was a good stay overall."
Daniel 1-night trip
Posted 1 day ago
SpringHill Suites by Marriott Florence
Comfort Suites Florence I-95

Comfort Suites Florence I-95

10/10 Excellent
"Parfait"
Meyranie 1-night trip
Posted 2 days ago
Comfort Suites Florence I-95

More cheap accommodation in Effingham

Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence

2038 W Lucas Street Florence SC
AU$103
29 Sept - 30 Sept
includes taxes & fees
8.6/10 Excellent! (2,736 reviews)
Howard Johnson by Wyndham Florence
Days Inn by Wyndham Florence Near Civic Center

Days Inn by Wyndham Florence Near Civic Center

140 Dunbarton Dr Florence SC
AU$110
29 Sept - 30 Sept
includes taxes & fees
Days Inn by Wyndham Florence Near Civic Center
Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC

1729 Mandeville Road Florence SC
AU$142
4 Oct - 5 Oct
includes taxes & fees
9/10 Wonderful! (2,461 reviews)
Park Inn by Radisson Florence, SC
The Inn at the Crossroads

The Inn at the Crossroads

128 West Main Street Lake City SC
AU$147
28 Oct - 29 Oct
includes taxes & fees
9.4/10 Exceptional! (989 reviews)
The Inn at the Crossroads
Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center

150 Dunbarton Dr Florence SC
AU$152
25 Oct - 26 Oct
includes taxes & fees
8.4/10 Very good! (381 reviews)
Quality Inn & Suites Florence Civic Center
Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area

527 Woody Jones Blvd Florence SC
AU$161
18 Oct - 19 Oct
includes taxes & fees
Comfort Inn & Suites Florence Center Area

Frequently asked questions

What is the best area to stay in Effingham?
The best area to stay in Effingham is near the intersection of US-301 and US-52, as this offers the most convenient access to amenities and the main travel routes.This area, often referred to as the Florence-Effingham commercial corridor, is characterised by a concentration of hotels, restaurants, and petrol stations just off the main highways. It's designed for convenience, especially for those travelling through or using Effingham as a base for exploring the wider region. You'll find most services clustered along these two major roads.For solo travellers or couples on a road trip, this area is ideal. Its primary benefit is the ease of getting on and off the highways, simplifying onward journeys. There are also several dining options ranging from casual eateries to sit-down restaurants, making it easy to grab a meal after a day of driving.
When is the best time to go to Effingham?
The best time to visit Effingham, South Carolina, is during the spring (March to May) and autumn (September to November) months.During these periods, the weather is pleasantly mild, with comfortable temperatures and lower humidity compared to the peak summer months. This makes it ideal for enjoying outdoor activities and exploring the local area without the intense heat. You'll find it's a great time for leisurely drives through the countryside or visiting nearby attractions.For those planning to attend local events or simply enjoy the comfortable weather, these seasons offer the best conditions.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if cancelled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Effingham.
How can I save on a hotel booking in Effingham with Expedia?
One Key™—Expedia's free travel rewards program—gives you instant access to discounts with Member Prices on Effingham hotels. Plus, you'll earn OneKeyCash™* on eligible bookings to use on future trips. Booking an Expedia hotel and flight package is another great way to save, where bundling can result in significant savings. *Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
How much is the nightly rate for a hotel in Effingham?
Prices for hotels in Effingham often vary, but you can find a great deal from AU$103 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for our cheapest rates.

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