East Side Pioneers Hotels, Rochester

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7 Dec - 8 Dec
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8 Dec - 9 Dec
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12 Dec - 14 Dec
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19 Dec - 21 Dec

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374 Cheap Hotels in East Side Pioneers - Specials, Reviews, & Last Minute Deals

Lobby
Hilton Rochester Mayo Clinic Area

Hilton Rochester Mayo Clinic Area

3.5 star property
East Side Pioneers
9.6 out of 10, Exceptional, (540)
"Had a great stay. Room was very clean and staff was very courteous. "
United States
Bonita
The price is AU$297
includes taxes & fees
13 Dec - 14 Dec
Hilton Rochester Mayo Clinic Area
Fridge, microwave, oven, stovetop
Broadway Plaza, Trademark Collection by Wyndham

Broadway Plaza, Trademark Collection by Wyndham

3.0 star property
East Side Pioneers
9.2 out of 10, Wonderful, (167)
"Great staff, clean room, spacious kitchen and living room."
United States
silvia
The price is AU$268
includes taxes & fees
22 Dec - 23 Dec
Broadway Plaza, Trademark Collection by Wyndham
Exterior
Hotel Indigo Rochester – Mayo Clinic Area by IHG

Hotel Indigo Rochester – Mayo Clinic Area by IHG

3.5 star property
East Side Pioneers
8.8 out of 10, Excellent, (882)
"Great room and stay!"
United States
Trevor
The price is AU$120
includes taxes & fees
27 Dec - 28 Dec
Hotel Indigo Rochester – Mayo Clinic Area by IHG
Front of property – evening/night
Kahler Grand Hotel

Kahler Grand Hotel

3.0 star property
Downtown Rochester, 1.3 km from East Side Pioneers
8.4 out of 10, Very good, (1804)
"The room was clean and very spacious. Easy to navigate and direct access to Mayo Clinic "
United States
Morgan
The price is AU$233
includes taxes & fees
11 Dec - 12 Dec
Kahler Grand Hotel
Serves lunch, dinner and happy hour
AmericInn by Wyndham Rochester Near Mayo Clinic

AmericInn by Wyndham Rochester Near Mayo Clinic

3.0 star property
3 km from East Side Pioneers
8.2 out of 10, Very good, (1125)
"Great location and value"
United States
Michelle
The price is AU$127
includes taxes & fees
12 Dec - 13 Dec
AmericInn by Wyndham Rochester Near Mayo Clinic
Free daily full breakfast
Econo Lodge Mayo Clinic Area

Econo Lodge Mayo Clinic Area

2.0 star property
3.4 km from East Side Pioneers
9.0 out of 10, Wonderful, (891)
"Good breakfast..shuttle service is excellent..super nice staff.."
United States
DALE K
The price is AU$109
includes taxes & fees
28 Dec - 29 Dec
Econo Lodge Mayo Clinic Area
Front of property
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

3.0 star property
7.3 km from East Side Pioneers
7.2 out of 10, Good, (1017)
"Breakfast was good. The staff was great. "
United States
Kjirsta
The price is AU$125
includes taxes & fees
9 Dec - 10 Dec
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
Courtyard
EVEN Hotel Rochester - Mayo Clinic Area by IHG

EVEN Hotel Rochester - Mayo Clinic Area by IHG

4.0 star property
Kutzky Park, 2.3 km from East Side Pioneers
9.4 out of 10, Exceptional, (952)
"Hotel was spotless, excellent staff and the breakfast was excellent. Late night eats at the restaurant and the food served was fantastic."
United States
Carmino
The price is AU$192
includes taxes & fees
26 Dec - 27 Dec
EVEN Hotel Rochester - Mayo Clinic Area by IHG
Exterior
Aspen Suites

Aspen Suites

3.0 star property
2.6 km from East Side Pioneers
9.0 out of 10, Wonderful, (686)
"I always stay at this hotel , love it clean comfortable rooms, they gave us vouchers for 4 free meals for Thanksgiving dinner"
United States
Cindy
The price is AU$264
includes taxes & fees
11 Dec - 12 Dec
Aspen Suites
In-room safe, desk, iron/ironing board, free cots/infant beds
Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic

Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic

2.0 star property
6.4 km from East Side Pioneers
7.8 out of 10, Good, (1002)
"Front staff are so kind and efficient. "
United States
Brenda
The price is AU$111
includes taxes & fees
12 Dec - 13 Dec
Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic
BBQ/picnic Area
Residence Inn by Marriott Rochester Mayo Clinic Area South

Residence Inn by Marriott Rochester Mayo Clinic Area South

3.0 star property
3.4 km from East Side Pioneers
9.6 out of 10, Exceptional, (242)
"Really nice property with a great staff and phenomenal outdoor seating area with fire pit and grill"
United States
Dwight
The price is AU$200
includes taxes & fees
14 Dec - 15 Dec
Residence Inn by Marriott Rochester Mayo Clinic Area South
Lobby
Super 8 by Wyndham Rochester Mayo Clinic Area

Super 8 by Wyndham Rochester Mayo Clinic Area

2.0 star property
3.7 km from East Side Pioneers
7.8 out of 10, Good, (1005)
"Great Stay"
United States
Aweng
The price is AU$88
includes taxes & fees
14 Dec - 15 Dec
Super 8 by Wyndham Rochester Mayo Clinic Area
Property entrance
Country Inn & Suites Rochester South Mayo Clinic

Country Inn & Suites Rochester South Mayo Clinic

3.0 star property
5.8 km from East Side Pioneers
8.4 out of 10, Very good, (1004)
"Clean room, fun staff."
United States
Thomas
The price is AU$168
includes taxes & fees
28 Dec - 29 Dec
Country Inn & Suites Rochester South Mayo Clinic
Exterior
SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys

SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys

3.0 star property
Kutzky Park, 2.4 km from East Side Pioneers
8.6 out of 10, Excellent, (931)
"This is a convenient place to stay when visiting Mayo."
United States
Faith
The price is AU$163
includes taxes & fees
19 Dec - 20 Dec
SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys
Exterior
Spark by Hilton Rochester South

Spark by Hilton Rochester South

3.0 star property
7 km from East Side Pioneers
9.4 out of 10, Exceptional, (301)
"The rooms are very nice and the staff is very friendly "
United States
Roberta
The price is AU$119
includes taxes & fees
4 Jan - 5 Jan 2026
Spark by Hilton Rochester South
Exterior
Aspen Select

Aspen Select

3.5 star property
2.6 km from East Side Pioneers
8.4 out of 10, Very good, (1002)
"Front desk staff was amazing, room was clean and the bed was comfortable! Location was perfect for us, right across the street from the hospital. Will definitely stay again, if the need arises! "
United States
Dana
Aspen Select
Coffee service
MainStay Suites Rochester South Mayo Clinic

MainStay Suites Rochester South Mayo Clinic

2.5 star property
5.6 km from East Side Pioneers
7.0 out of 10, Good, (89)
"Staff is friendly "
United States
Merry
The price is AU$95
includes taxes & fees
15 Dec - 16 Dec
MainStay Suites Rochester South Mayo Clinic
Exterior
Baymont by Wyndham Rochester Mayo Clinic Area

Baymont by Wyndham Rochester Mayo Clinic Area

2.5 star property
2.3 km from East Side Pioneers
7.2 out of 10, Good, (716)
"Spotless clean"
United States
Brit
The price is AU$103
includes taxes & fees
14 Dec - 15 Dec
Baymont by Wyndham Rochester Mayo Clinic Area
Executive Room, 2 Queen Beds, Refrigerator & Microwave, Pool View (Living Room)
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

2.5 star property
3.8 km from East Side Pioneers
8.2 out of 10, Very good, (783)
"Great place to stay. Freindly staff"
United States
joel
The price is AU$163
includes taxes & fees
11 Dec - 12 Dec
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
View from property
Marriott Rochester Mayo Clinic

Marriott Rochester Mayo Clinic

3.5 star property
Downtown Rochester, 1.2 km from East Side Pioneers
8.2 out of 10, Very good, (520)
"All staff were very nice and friendly and willing to help with whatever we needed. "
United States
Becky
The price is AU$293
includes taxes & fees
12 Dec - 13 Dec
Marriott Rochester Mayo Clinic
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Our guide on where to stay in East Side Pioneers

Find the best East Side Pioneers areas for the activities you enjoy most.
Rochester featuring skyline and a city
Photo by Howard Lower Photography
Open Photo by Howard Lower Photography

Downtown Rochester

If you're spending some time in Downtown Rochester, Mayo Civic Center and Rochester Civic Theater are top sights worth seeing.

Kutzky Park

While there might not be top attractions in Kutzky Park, you can explore the larger area and discover places like Soldiers Field Veterans Memorial and Mayo Civic Center.

Rochester featuring forests and a river or creek
Photo by Chad Johnson
Open Photo by Chad Johnson

Historic Southwest

While visiting Historic Southwest, you might make a stop by sights like Soldiers Field Veterans Memorial and Plummer House.

Slatterly Park

While Slatterly Park isn't home to many top sights, Rochester Art Center and Soldiers Field Veterans Memorial are some notable places to visit nearby.

Folwell

Though Folwell may not have many top sights, you can venture to the surrounding area to see attractions like Soldiers Field Veterans Memorial and Apache Mall.

Top East Side Pioneers Hotel Reviews

Kahler Inn and Suites - Mayo Clinic Area

Kahler Inn and Suites - Mayo Clinic Area

10/10 Excellent
"all the above "
Jerry 2-night trip
Posted 1 day ago
Kahler Inn and Suites - Mayo Clinic Area

Frequently asked questions

What's it like in East Side Pioneers?
Travellers are sure to enjoy a stay in Rochester's East Side Pioneers neighbourhood. Are you looking for East Side Pioneers travel tips? Make sure that you visit Rochester Art Center and Rochester Civic Theater while you're in the neighbourhood.
What's the best accommodation in East Side Pioneers?
Based on Expedia customer reviews, Hilton Rochester Mayo Clinic Area is the highest ranked property in East Side Pioneers. This hotel is a short 6-minute walk from Mayo Clinic, and it offers a full-service spa and 2 restaurants. Another favourite option in the neighbourhood is Hotel Indigo Rochester – Mayo Clinic Area by IHG.
How many hotels should I expect to find in East Side Pioneers?
If you're searching for places to stay in Rochester, choose from one of Expedia's 17 hotels and other accommodation options in East Side Pioneers.
If I need to cancel my hotel reservation in East Side Pioneers, will I receive a refund?
Yes! The majority of room reservations are fully refundable if you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If your reservation is non-refundable, you may still be able to cancel and receive a refund within a 24-hour period of booking. Put your dates in and click on "Search", then use the filter option "fully refundable" to get the best deals in East Side Pioneers.
What can I see and do in this Rochester neighbourhood?
Spend some time exploring the natural setting of East Side Pioneers with a visit to Silver Lake Park and Mayo Park. You could also plan a visit to Rochester Art Center or Rochester Civic Theater while you're in the neighbourhood. A few places to visit in the area around East Side Pioneers include Mayo Civic Center, Rochester Public Library and Shops University Square. While you're out sightseeing, Plummer Building and Soldiers Field Veterans Memorial are a couple of additional sights to visit in Rochester.

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