East Side Pioneers Hotels, Rochester

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
9 Mar - 10 Mar
Tomorrow
10 Mar - 11 Mar
This weekend
13 Mar - 15 Mar
Next weekend
20 Mar - 22 Mar

Filter by

Guest rating
Guest rating
Star rating

Our top choices for East Side Pioneers hotels

Presidential Suite, Multiple Beds | Living area

Hilton Rochester Mayo Clinic Area

Hilton Rochester Mayo Clinic Area
3.5 star property
East Side Pioneers
9.6 out of 10, Exceptional, (576 reviews)
"Great hotel. Best in the city by far. "
Canada
jonathan
The price is AU$281
includes taxes & fees
20 Mar - 21 Mar
Hilton Rochester Mayo Clinic Area
Breakfast, lunch, dinner served; American cuisine

Hotel Indigo Rochester – Mayo Clinic Area by IHG

Hotel Indigo Rochester – Mayo Clinic Area by IHG
3.5 star property
East Side Pioneers
8.8 out of 10, Excellent, (956 reviews)
"Comfy beds, relatively quiet, great amenities, restaurant/bar is excellent as well. Always stay there when I have to stay in Rochester."
United States
Nicole
The price is AU$147
includes taxes & fees
3 Apr - 4 Apr
Hotel Indigo Rochester – Mayo Clinic Area by IHG
Two-Bedroom Apartment - Mobility Accessible/Non-Smoking

Broadway Plaza, Trademark Collection by Wyndham

Broadway Plaza, Trademark Collection by Wyndham
3.0 star property
East Side Pioneers
9.2 out of 10, Wonderful, (174 reviews)
"As always excellent staff, clean and comfortable rooms. Great central location. "
Canada
Anita
The price is AU$277
includes taxes & fees
14 Mar - 15 Mar
Broadway Plaza, Trademark Collection by Wyndham
Lobby

Comfort Inn & Suites Rochester South Mayo Clinic

Comfort Inn & Suites Rochester South Mayo Clinic
2.0 star property
12.2 km from East Side Pioneers
8.8 out of 10, Excellent, (1,002 reviews)
"Clean rooms, friendly staff, good stay"
United States
Della
The price is AU$116
includes taxes & fees
8 Apr - 9 Apr
Comfort Inn & Suites Rochester South Mayo Clinic
Reception

America's Stay Inn Stewartville

America's Stay Inn Stewartville
2.5 star property
17.5 km from East Side Pioneers
8.0 out of 10, Very good, (427 reviews)
"Good price, clean room."
United States
Susan
America's Stay Inn Stewartville
Reception

Spark by Hilton Rochester South

Spark by Hilton Rochester South
3.0 star property
7 km from East Side Pioneers
9.4 out of 10, Exceptional, (393 reviews)
"Clean, quiet and a really nice place to stay."
United States
Tony
The price is AU$112
includes taxes & fees
16 Mar - 17 Mar
Spark by Hilton Rochester South
Front of property

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
3.0 star property
7.2 km from East Side Pioneers
7.2 out of 10, Good, (1,039 reviews)
"Staff was courteous and breakfast was well stocked."
United States
Doug
The price is AU$119
includes taxes & fees
20 Mar - 21 Mar
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
Exterior

Holiday Inn Express Rochester South - Mayo Area by IHG

Holiday Inn Express Rochester South - Mayo Area by IHG
2.5 star property
6.9 km from East Side Pioneers
8.8 out of 10, Excellent, (1,011 reviews)
"Clean room, clean hotel, friendly staff Would stay here again."
United States
Chee
The price is AU$157
includes taxes & fees
23 Mar - 24 Mar
Holiday Inn Express Rochester South - Mayo Area by IHG
Reception

Hampton Inn Rochester-South

Hampton Inn Rochester-South
2.5 star property
3.3 km from East Side Pioneers
9.0 out of 10, Wonderful, (1,016 reviews)
"Was a clean room that we had the hotel was quiet at night, friendly staff, and a very good breakfast buffet"
United States
Larry
The price is AU$138
includes taxes & fees
5 Apr - 6 Apr
Hampton Inn Rochester-South
Indoor pool, open 9:00 AM to 10:00 PM, pool umbrellas, pool loungers

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
2.5 star property
3.8 km from East Side Pioneers
8.4 out of 10, Very good, (845 reviews)
"Check in staff was great! "
United States
Paulette
The price is AU$129
includes taxes & fees
16 Mar - 17 Mar
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
Terrace/patio

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
3.0 star property
Historic Southwest, 1.7 km from East Side Pioneers
8.6 out of 10, Excellent, (1,008 reviews)
"Clean rooms, good breakfast, close to Mayo, enjoyed Twigs."
United States
Jerry
The price is AU$207
includes taxes & fees
24 Mar - 25 Mar
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
Free daily full breakfast

Econo Lodge Mayo Clinic Area

Econo Lodge Mayo Clinic Area
2.0 star property
3.4 km from East Side Pioneers
9.0 out of 10, Wonderful, (948 reviews)
"Very clean and staff was friendly. "
United States
Robert
The price is AU$110
includes taxes & fees
21 Mar - 22 Mar
Econo Lodge Mayo Clinic Area
Property entrance

Country Inn & Suites Rochester South Mayo Clinic

Country Inn & Suites Rochester South Mayo Clinic
3.0 star property
5.8 km from East Side Pioneers
8.4 out of 10, Very good, (1,008 reviews)
"Rooms are always clean wonderful service from the staff. It’s a great place to stay."
United States
Jamie
The price is AU$145
includes taxes & fees
30 Mar - 31 Mar
Country Inn & Suites Rochester South Mayo Clinic
Front of property

Aspen Suites

Aspen Suites
3.0 star property
2.6 km from East Side Pioneers
9.0 out of 10, Wonderful, (755 reviews)
"Very clean and nice staff"
United States
Kirk
Aspen Suites
View from property

Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys

Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys
3.0 star property
Kutzky Park, 3 km from East Side Pioneers
9.6 out of 10, Exceptional, (692 reviews)
"Clean rooms with all necessities and a wonderful front desk staff. "
United States
Barbara
The price is AU$161
includes taxes & fees
3 Apr - 4 Apr
Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys
Indoor pool

Residence Inn by Marriott Rochester Mayo Clinic Area South

Residence Inn by Marriott Rochester Mayo Clinic Area South
3.0 star property
3.2 km from East Side Pioneers
9.6 out of 10, Exceptional, (269 reviews)
"Staff was great and helpful, lovely room!, quiet area, restaurants nearby"
United States
Ann Marie
The price is AU$226
includes taxes & fees
15 Mar - 16 Mar
Residence Inn by Marriott Rochester Mayo Clinic Area South
Serves lunch, dinner and happy hour

AmericInn by Wyndham Rochester Near Mayo Clinic

AmericInn by Wyndham Rochester Near Mayo Clinic
3.0 star property
3 km from East Side Pioneers
8.2 out of 10, Very good, (1,224 reviews)
"Pleasant hotel."
United States
Veronica
The price is AU$121
includes taxes & fees
21 Mar - 22 Mar
AmericInn by Wyndham Rochester Near Mayo Clinic
In-room safe, desk, iron/ironing board, free cots/infant beds

Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic

Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic
2.0 star property
6.4 km from East Side Pioneers
8.0 out of 10, Very good, (1,004 reviews)
"Clean room, decent breakfast choices "
United States
Connie
The price is AU$107
includes taxes & fees
15 Mar - 16 Mar
Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic
Restaurant

Hampton Inn & Suites Rochester-North

Hampton Inn & Suites Rochester-North
2.5 star property
8.2 km from East Side Pioneers
9.2 out of 10, Wonderful, (1,004 reviews)
"Good staff great place "
United States
Juan
The price is AU$162
includes taxes & fees
18 Mar - 19 Mar
Hampton Inn & Suites Rochester-North
View from property

Kahler Grand Hotel

Kahler Grand Hotel
3.0 star property
Downtown Rochester, 1.3 km from East Side Pioneers
8.4 out of 10, Very good, (1,950 reviews)
"Always an enjoyable place in a good location."
United States
Thomas
Kahler Grand Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Our guide on where to stay in East Side Pioneers

Find the best East Side Pioneers areas for the activities you enjoy most.
default

Downtown Rochester

If you're spending some time in Downtown Rochester, Mayo Civic Center and Rochester Civic Theater are top sights worth seeing.

Rochester, Minnesota. Civic Center, River, Skyline

Kutzky Park

While there might not be top attractions in Kutzky Park, you can explore the larger area and discover places like Soldiers Field Veterans Memorial and Mayo Civic Center.

Rochester showing a garden, a memorial and night scenes
Photo by Soldiers Field Veterans Memorial
Open Photo by Soldiers Field Veterans Memorial

Historic Southwest

While visiting Historic Southwest, you might make a stop by sights like Soldiers Field Veterans Memorial and Plummer House.

Split in path, snowy forest and trail in Quarry Hill Nature Center, Rochester, Minnesota on a snowy day

Slatterly Park

While Slatterly Park isn't home to many top sights, Rochester Art Center and Soldiers Field Veterans Memorial are some notable places to visit nearby.

Northrup

When in Northrup, you can plan a visit to Rochester Civic Theater and Mayo Civic Center, some noteworthy sights in the nearby area.

Top East Side Pioneers Hotel Reviews

Kahler Grand Hotel

Kahler Grand Hotel

10/10 Excellent
"Great place to stay for Mayo checkups, always clean & couldn’t be more convenient "
Jason 1-night trip
Posted 1 hour ago
Kahler Grand Hotel

Frequently asked questions

What's it like in East Side Pioneers?
Travellers are sure to enjoy a stay in Rochester's East Side Pioneers neighbourhood. Are you looking for East Side Pioneers travel tips? Make sure that you visit Rochester Art Center and Rochester Civic Theater while you're in the neighbourhood.
What's the best accommodation in East Side Pioneers?
Based on Expedia customer reviews, Hilton Rochester Mayo Clinic Area is the highest ranked property in East Side Pioneers. This hotel is a short 6-minute walk from Mayo Clinic, and it offers a full-service spa and 2 restaurants. Another favourite option in the neighbourhood is Hotel Indigo Rochester – Mayo Clinic Area by IHG.
How many hotels should I expect to find in East Side Pioneers?
If you're searching for places to stay in Rochester, choose from one of Expedia's 18 hotels and other accommodation options in East Side Pioneers.
If I need to cancel my hotel reservation in East Side Pioneers, will I receive a refund?
Yes! The majority of room reservations are fully refundable if you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If your reservation is non-refundable, you may still be able to cancel and receive a refund within a 24-hour period of booking. Put your dates in and click on "Search", then use the filter option "fully refundable" to get the best deals in East Side Pioneers.
What can I see and do in this Rochester neighbourhood?
Spend some time exploring the natural setting of East Side Pioneers with a visit to Mayo Park and Silver Lake Park. You could also plan a visit to Rochester Art Center or Rochester Civic Theater while you're in the neighbourhood. A few places to visit in the area around East Side Pioneers include Mayo Civic Center, Rochester Public Library and Shops University Square. While you're out sightseeing, Plummer Building and Soldiers Field Veterans Memorial are a couple of additional sights to visit in Rochester.

Explore a world of travel with Expedia