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Check prices for these dates

Tonight
6 Mar - 7 Mar
Tomorrow
7 Mar - 8 Mar
This weekend
6 Mar - 8 Mar
Next weekend
13 Mar - 15 Mar

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Our top choices for East Prairie hotels

Lobby sitting area

The Riverstone Hotel Charleston-Sikeston

The Riverstone Hotel Charleston-Sikeston
2.5 star property
Charleston
6.8 out of 10, (408 reviews)
"The staff was very friendly and accommodating "
United States
Arturo
The price is AU$111
includes taxes & fees
7 Mar - 8 Mar
The Riverstone Hotel Charleston-Sikeston
Laptop workspace, blackout curtains, free cots/infant beds, free WiFi

Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO
2.0 star property
Charleston
6.8 out of 10, (625 reviews)
"Affordable for a quick one night stay. Restaurant and gas station next to hotel."
United States
Annette
The price is AU$98
includes taxes & fees
7 Mar - 8 Mar
Super 8 by Wyndham Charleston/Sikeston East MO
Indoor pool, outdoor pool

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO
3.0 star property
Sikeston
9.4 out of 10, Exceptional, (1,010 reviews)
"As always it was a perfect visit"
United States
John
The price is AU$154
includes taxes & fees
15 Mar - 16 Mar
Drury Inn & Suites Sikeston, MO
Lobby

Hospitality House Union City I 69 / US 51

Hospitality House Union City I 69 / US 51
2.5 star property
Union City
6.8 out of 10, (383 reviews)
"Easy to check in.. Clean Room..Lots of food options near by.. "
United States
Pooran
The price is AU$102
includes taxes & fees
18 Mar - 19 Mar
Hospitality House Union City I 69 / US 51
Lobby

Sleep Inn at Discovery Park of America

Sleep Inn at Discovery Park of America
2.5 star property
Union City
9.2 out of 10, Wonderful, (359 reviews)
"The rooms are big and the property is spotless!"
United States
debbie
The price is AU$121
includes taxes & fees
5 Apr - 6 Apr
Sleep Inn at Discovery Park of America
Exterior

Holiday Inn Express & Suites Union City by IHG

Holiday Inn Express & Suites Union City by IHG
2.5 star property
Union City
9.2 out of 10, Wonderful, (314 reviews)
"The room was spacious & clean. The complimentary breakfast was nice. Very quiet place and next to a unique tourist attraction."
United States
Angela
The price is AU$173
includes taxes & fees
5 Apr - 6 Apr
Holiday Inn Express & Suites Union City by IHG
Free daily full breakfast

Best Western Plus Sikeston I-55

Best Western Plus Sikeston I-55
2.5 star property
Sikeston
8.4 out of 10, Very good, (1,005 reviews)
"Great stay, everything was clean and comfortable. "
United States
Charles
The price is AU$133
includes taxes & fees
26 Mar - 27 Mar
Best Western Plus Sikeston I-55
Exterior

Hampton Inn Sikeston

Hampton Inn Sikeston
2.5 star property
Sikeston
9.0 out of 10, Wonderful, (494 reviews)
"Very Clean room, friendly staff, breakfast in the morning. Will be staying again! "
United States
Affinity
The price is AU$150
includes taxes & fees
29 Mar - 30 Mar
Hampton Inn Sikeston
Free buffet breakfast

Quality Inn Union City US 51

Quality Inn Union City US 51
2.5 star property
Union City
8.4 out of 10, Very good, (499 reviews)
"Nice room"
Mexico
José Ricardo
The price is AU$114
includes taxes & fees
22 Mar - 23 Mar
Quality Inn Union City US 51
Lobby

Country Hearth Inn & Suites Union City

Country Hearth Inn & Suites Union City
2.5 star property
Union City
8.6 out of 10, Excellent, (555 reviews)
"Very clean nice staff and well run "
United States
zach
The price is AU$121
includes taxes & fees
7 Mar - 8 Mar
Country Hearth Inn & Suites Union City
Room, 1 King Bed, Non Smoking | View from room

Eagle Inn Charleston

Eagle Inn Charleston
2.0 star property
Charleston
6.6 out of 10, (105 reviews)
"Convenient "
United States
Marcelle
The price is AU$101
includes taxes & fees
7 Mar - 8 Mar
Eagle Inn Charleston
1 bedroom, desk, laptop workspace, blackout curtains

Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston
2.0 star property
Sikeston
7.2 out of 10, Good, (1,004 reviews)
"Everything was excellent"
United States
James
The price is AU$111
includes taxes & fees
9 Mar - 10 Mar
Days Inn and Suites by Wyndham Sikeston
Premier Room, 1 Bedroom, Non Smoking

New Orleans Inn Portageville

New Orleans Inn Portageville
2.5 star property
Portageville
8.0 out of 10, Very good, (747 reviews)
"Parking was good, staff was great "
United States
Corey
New Orleans Inn Portageville
Room, 1 King Bed, Accessible, Non Smoking

Super 8 by Wyndham Sikeston/Miner Area

Super 8 by Wyndham Sikeston/Miner Area
2.0 star property
Sikeston
6.8 out of 10, (599 reviews)
"Great place"
United States
Misty
The price is AU$98
includes taxes & fees
8 Mar - 9 Mar
Super 8 by Wyndham Sikeston/Miner Area
Desk, free WiFi, bed sheets, alarm clocks

Comfort Inn & Suites Sikeston I-55

Comfort Inn & Suites Sikeston I-55
2.5 star property
Sikeston
8.4 out of 10, Very good, (288 reviews)
"The hotel was very clean, beds were comfortable, and staff was friendly and helpful."
United States
aileen
The price is AU$152
includes taxes & fees
11 Mar - 12 Mar
Comfort Inn & Suites Sikeston I-55
Suite, 2 Queen Beds, Non Smoking

MainStay Suites Union City, TN

MainStay Suites Union City, TN
2.5 star property
Union City
8.6 out of 10, Excellent, (44 reviews)
"Very clean room, friendly staff! I would highly recommend this place! "
United States
Lydia
The price is AU$185
includes taxes & fees
15 Mar - 16 Mar
MainStay Suites Union City, TN
Free daily continental breakfast

Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG
2.5 star property
Sikeston
8.6 out of 10, Excellent, (449 reviews)
"Stay was excellent "
United States
Kourtney
The price is AU$150
includes taxes & fees
22 Mar - 23 Mar
Holiday Inn Express & Suites Sikeston Southwest by IHG
Terrace/patio

Hampton Inn Union City

Hampton Inn Union City
2.5 star property
Union City
9.6 out of 10, Exceptional, (173 reviews)
"Spotless , friendly staff."
United States
Gail
The price is AU$195
includes taxes & fees
22 Mar - 23 Mar
Hampton Inn Union City
Individually decorated, individually furnished, desk, blackout curtains

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
2.5 star property
Sikeston
8.4 out of 10, Very good, (749 reviews)
"Room was clean. Fairly quiet room. Front desk was kind. Would stay here again. ."
United States
Becky
The price is AU$111
includes taxes & fees
7 Mar - 8 Mar
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Property amenity

Fairfield Inn & Suites by Marriott Sikeston

Fairfield Inn & Suites by Marriott Sikeston
3.0 star property
Sikeston
9.4 out of 10, Exceptional, (61 reviews)
"Clean rooms great staff"
United States
IRA
The price is AU$163
includes taxes & fees
12 Mar - 13 Mar
Fairfield Inn & Suites by Marriott Sikeston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular East Prairie attractions

Big Oak Tree State Park

3.8/5 (8 reviews)
You can take time to visit Big Oak Tree State Park during your travels to East Prairie. While you're in the area, wander around the parks.
See properties

Learn more about East Prairie

Discover local heritage at the East Prairie Historical Museum, where artefacts tell the storey of this Mississippi County town. Join the community for the annual Tour de Corn cycling event or explore nearby Big Oak Tree State Park for impressive ancient trees and wildlife viewing.

See all hotels in East Prairie
The Mississippi River near Hannibal, Missouri, USA

Top East Prairie Hotel Reviews

Recent Reviews in East Prairie

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

8/10 Good
"Very clean but sometimes noisy from outside traffic"
Denise 1-night trip
Posted 6 hours ago
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

More cheap accommodation in East Prairie

Super 8 by Wyndham Sikeston/Miner Area

Super 8 by Wyndham Sikeston/Miner Area

2609 E Malone Ave Sikeston MO
The price is AU$98 per night from 8 Mar to 9 Mar
AU$98
8 Mar - 9 Mar
includes taxes & fees
6.8/10 (599 reviews)

Frequently asked questions

What's the best place for a stay in East Prairie?
Drury Inn & Suites Sikeston, MO, located 11.4 mi (18.4 km) from the heart of East Prairie, is a top choice for your stay, based on our traveller data. Other good choices for your trip to the area are Hampton Inn Sikeston and Sleep Inn at Discovery Park of America. See all available top hotels, or vacation rentals in East Prairie.
What are some of the best holiday rentals that East Prairie has to offer?
Duck Hunting, Fishing or Relaxing Family Vacation: This holiday home rental outside of East Prairie is located on a lake, and has a patio, a garden and a BBQ to put you at ease in your new surroundings. It has 3 bedrooms, as well as a kitchen with a dishwasher, a fridge and a stovetop, so that you can cook with friends or family. See all vacation rentals in East Prairie.
If I need to cancel my hotel reservation in East Prairie, will I receive a refund?
Yes, you'll find most room reservations are fully refundable if cancelled before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If your reservation is non-refundable, you might still have the option to cancel and get a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in East Prairie.
How is it staying in East Prairie?
Visitors will definitely enjoy all that East Prairie has to offer. There are 33 hotels and other accommodation options in the surrounding area. Find out more about East Prairie.
What are the top places to visit in East Prairie?
The picturesque setting of Big Oak Tree State Park and Mississippi River exemplify the area's natural beauty. You'll also find Central Park and Sikeston Depot Museum in the area. Take a look at what more there is to see and do in Expedia's East Prairie guide.
What's the weather like in East Prairie?
The hottest months are usually July and August, with an average temperature of 25°C, while the coldest months are January and February, with an average of 5°C. Average annual precipitation for East Prairie is 1522 mm.

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