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15 Sept - 16 Sept
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Top hotels and accommodation in East Prairie

Days Inn and Suites by Wyndham Sikeston
1 bedroom, desk, laptop workspace, blackout curtains

Days Inn and Suites by Wyndham Sikeston

2.0 star property
7.2 out of 10, Good, (1004)
"Staff were great."
The price is AU$108
includes taxes & fees
21 Sept - 22 Sept
Days Inn and Suites by Wyndham Sikeston
Hampton Inn Sikeston
Exterior

Hampton Inn Sikeston

2.5 star property
8.8 out of 10, Excellent, (392)
"Very happy with the service and cleanliness of the rooms !!"
The price is AU$181
includes taxes & fees
28 Sept - 29 Sept
Hampton Inn Sikeston
Holiday Inn Express & Suites Sikeston Southwest by IHG
Exterior

Holiday Inn Express & Suites Sikeston Southwest by IHG

2.5 star property
8.6 out of 10, Excellent, (429)
"Close in eating and shopping "
The price is AU$191
includes taxes & fees
3 Oct - 4 Oct
Holiday Inn Express & Suites Sikeston Southwest by IHG
Best Western Plus Sikeston
Free daily full breakfast

Best Western Plus Sikeston

2.5 star property
8.4 out of 10, Very good, (1007)
"Staff was friendly and room was very clean. A very comfortable stay"
The price is AU$144
includes taxes & fees
21 Sept - 22 Sept
Best Western Plus Sikeston
Super 8 by Wyndham Sikeston/Miner Area
Room, 1 King Bed, Accessible, Non Smoking

Super 8 by Wyndham Sikeston/Miner Area

2.0 star property
6.6 out of 10, (554)
"I enjoyed our stay"
The price is AU$108
includes taxes & fees
22 Sept - 23 Sept
Super 8 by Wyndham Sikeston/Miner Area
Sleep Inn at Discovery Park of America
Lobby

Sleep Inn at Discovery Park of America

2.5 star property
9.0 out of 10, Wonderful, (276)
"Great place and clean"
The price is AU$150
includes taxes & fees
28 Sept - 29 Sept
Sleep Inn at Discovery Park of America
Pear Tree Inn Sikeston
Lobby

Pear Tree Inn Sikeston

2.5 star property
9.4 out of 10, Exceptional, (1002)
"I love this hotel! Have stayed several times and will definitely stay again. The rooms are always very clean and the staff is so friendly and helpful. I highly recommend this hotel!"
The price is AU$133
includes taxes & fees
21 Sept - 22 Sept
Pear Tree Inn Sikeston
Super 8 by Wyndham Charleston/Sikeston East MO
Front of property – evening/night

Super 8 by Wyndham Charleston/Sikeston East MO

2.0 star property
6.6 out of 10, (590)
"Rooms was clean "
The price is AU$98
includes taxes & fees
16 Sept - 17 Sept
Super 8 by Wyndham Charleston/Sikeston East MO
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Hallway

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

2.5 star property
8.4 out of 10, Very good, (678)
"Everything was nice"
The price is AU$95
includes taxes & fees
16 Sept - 17 Sept
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Hospitality House Union City I 69 / US 51
Seasonal outdoor pool

Hospitality House Union City I 69 / US 51

2.5 star property
6.8 out of 10, (332)
"There was a cute chilling area and SOME nice ppl but overall it was not the greatest mostly hygiene wise "
The price is AU$97
includes taxes & fees
14 Oct - 15 Oct
Hospitality House Union City I 69 / US 51
Comfort Inn & Suites Sikeston I-55
Exterior

Comfort Inn & Suites Sikeston I-55

2.5 star property
8.4 out of 10, Very good, (271)
"The facility was very nice. "
The price is AU$152
includes taxes & fees
21 Sept - 22 Sept
Comfort Inn & Suites Sikeston I-55
Drury Inn & Suites Sikeston, MO
Property amenity

Drury Inn & Suites Sikeston, MO

3.0 star property
9.4 out of 10, Exceptional, (1002)
"The pool the happy hour was really nice very relaxed nice activities front desk was very helpful at all times"
The price is AU$156
includes taxes & fees
21 Sept - 22 Sept
Drury Inn & Suites Sikeston, MO
Quality Inn Union City US 51
Lobby

Quality Inn Union City US 51

2.5 star property
8.4 out of 10, Very good, (468)
"Quite, clean, and good location."
The price is AU$120
includes taxes & fees
28 Sept - 29 Sept
Quality Inn Union City US 51
Quality Inn Cairo I-57
Lobby

Quality Inn Cairo I-57

2.5 star property
6.6 out of 10, (268)
"The room smelled like pee and the carpets, hallway and room were filthy. The shower was filthy with paint peeling and mold on the ceiling "
The price is AU$113
includes taxes & fees
14 Oct - 15 Oct
Quality Inn Cairo I-57
Fairfield Inn & Suites by Marriott Sikeston
Bar (on property)

Fairfield Inn & Suites by Marriott Sikeston

2.5 star property
9.4 out of 10, Exceptional, (22)
"Hotel was clean, the toilets could use some attention, but staff was friendly and the breakfast was good"
The price is AU$172
includes taxes & fees
28 Sept - 29 Sept
Fairfield Inn & Suites by Marriott Sikeston
Country Hearth Inn & Suites Union City
Reception

Country Hearth Inn & Suites Union City

2.5 star property
8.6 out of 10, Excellent, (533)
"Very good!"
The price is AU$129
includes taxes & fees
16 Sept - 17 Sept
Country Hearth Inn & Suites Union City
Travel Inn
Gazebo

Travel Inn

2.5 star property
5.6 out of 10, (110)
"Great place"
Travel Inn
Holiday Inn Express & Suites Union City by IHG
Free daily buffet breakfast

Holiday Inn Express & Suites Union City by IHG

2.5 star property
9.4 out of 10, Exceptional, (291)
"Great location Very quite. "
The price is AU$205
includes taxes & fees
3 Oct - 4 Oct
Holiday Inn Express & Suites Union City by IHG
TownePlace Suites by Marriott Sikeston
Bar (on property)

TownePlace Suites by Marriott Sikeston

3.0 star property
8.4 out of 10, Very good, (5)
"I loved all of what this property had to offer "
The price is AU$208
includes taxes & fees
21 Sept - 22 Sept
TownePlace Suites by Marriott Sikeston
New Orleans Inn Portageville
Premier Room, 1 Bedroom, Non Smoking

New Orleans Inn Portageville

2.5 star property
8.0 out of 10, Very good, (692)
"Very nice stay"
New Orleans Inn Portageville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top East Prairie Hotel Reviews

New Orleans Inn Portageville

New Orleans Inn Portageville

10/10 Excellent
"Had a great time "
Shyianne 1-night trip
Posted 6 days ago
New Orleans Inn Portageville

More cheap accommodation in East Prairie

More cheap accommodation in East Prairie

Best Western Plus Sikeston

Best Western Plus Sikeston

120 S Interstate Drive, Sikeston, MO
The price is AU$144 per night from 21 Sept to 22 Sept
AU$144
21 Sept - 22 Sept
includes taxes & fees
8.2/10 Very Good! (1,003 reviews)

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Explore a world of travel with Expedia

Frequently asked questions

What's the best place for a stay in East Prairie?

Drury Inn & Suites Sikeston, MO, located 11.4 mi (18.4 km) from the heart of East Prairie, is a top choice for your stay, based on our traveller data. Other good choices for your trip to the area are Sleep Inn at Discovery Park of America and Best Western Plus Sikeston. See all available top hotels, or vacation rentals in East Prairie.

What are some of the best holiday rentals that East Prairie has to offer?

Duck Hunting, Fishing or Relaxing Family Vacation: This holiday home rental outside of East Prairie is located on a lake, and has a patio, a garden and a BBQ to put you at ease in your new surroundings. It has 3 bedrooms, as well as a kitchen with a dishwasher, a fridge and a stovetop, so that you can cook with friends or family. See all vacation rentals in East Prairie.

If I need to cancel my hotel reservation in East Prairie, will I receive a refund?

Yes, you'll find most room reservations are fully refundable if cancelled before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If your reservation is non-refundable, you might still have the option to cancel and get a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in East Prairie.

How is it staying in East Prairie?

Visitors will definitely enjoy all that East Prairie has to offer. There are 30 hotels and other accommodation options in the surrounding area. Find out more about East Prairie.

What are the top places to visit in East Prairie?

The picturesque setting of Big Oak Tree State Park and Mississippi River exemplify the area's natural beauty. You'll also find Central Park and Sikeston Depot Museum in the area. Take a look at what more there is to see and do in Expedia's East Prairie guide.

What's the weather like in East Prairie?

The hottest months are usually July and August, with an average temperature of 25°C, while the coldest months are January and February, with an average of 5°C. Average annual precipitation for East Prairie is 1522 mm.