East Prairie Hotel & Accommodation Deals 2026 from AU$90 - Compare prices by date

A tree-lined landscape with a river and fields.

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Our top choices for East Prairie hotels

An indoor swimming pool with a 3 FT depth marker, a metal ladder, and a tiled floor.

A hotel room with a patterned sofa, a yellow ottoman, a desk with a TV, and a framed picture on the wall.

A spacious lobby with a polished floor, seating areas, and modern lighting fixtures.

An outdoor seating area with sofas and planters, surrounded by a building with large windows and a brick wall.

1. Drury Inn & Suites Sikeston, MO

Sikeston

Scott Andrew

AU$150

includes taxes & fees

13 Sept - 14 Sept

An outdoor seating area with a circular fire pit surrounded by chairs, a covered patio, and a building with large windows in the background.

A modern lobby with a green sofa, two armchairs, a wooden coffee table, and a patterned rug.

A modern hotel building with a sign reading "TOWNPLACE SUITES BY MARRIOTT" and "Fairfield BY MARRIOTT".

A modern indoor swimming pool with clear glass walls, a tiled deck, and multiple lounge chairs.

2. Fairfield Inn & Suites by Marriott Sikeston

Sikeston

Allen

AU$159

includes taxes & fees

13 Sept - 14 Sept

A hotel lobby with a central bar area, multiple dining tables and chairs, large windows, and a patterned carpet.

A hotel with a covered entrance, a sign indicating a restaurant, and a well-lit parking area.

An indoor swimming pool with clear water, surrounded by lounge chairs and tables, and large windows providing natural light.

A reception area with a wooden reception desk, a large painting on the wall, and a potted plant.

3. Best Western Plus Sikeston I-55

Sikeston

Crystal

AU$138

includes taxes & fees

20 Sept - 21 Sept

A hotel room with two beds, a desk with a chair, a TV, and a window with curtains.

A reception area with a reception desk, a large wall-mounted sign, and a potted plant.

A kitchenette with a coffee machine, a kettle, and storage shelves.

A buffet with various food items, including omelets and baked goods, served in metal containers.

4. Holiday Inn Express & Suites Sikeston Southwest by IHG

Sikeston

Melissa

AU$168

includes taxes & fees

13 Sept - 14 Sept

A Hampton Inn with a stone facade, outdoor seating area, and a fire pit.

An indoor swimming pool with lounge chairs, a lifeguard stand, and large windows offering a view of the outside.

A hotel lobby with a bar area, seating arrangements, and a large window providing natural light.

A conference room with a large rectangular table, six chairs with patterned upholstery, two modern ceiling lights, a bowl of fruit on the table, and large windows with curtains.

5. Hampton Inn Sikeston

Sikeston

Jeffrey

AU$160

includes taxes & fees

13 Sept - 14 Sept

A building with a fountain and flower beds in front.

A hotel room with a large bed, two bedside tables with lamps, a chair, a small table, and a picture on the wall.

A reception area with a stone wall, wooden cabinets, and a sign for The Riverstone Hotel.

A modern kitchen with dark wooden cabinets, a central island, and a ceiling fan.

6. The Riverstone Hotel Charleston-Sikeston

Charleston

Bobby

AU$102

includes taxes & fees

8 Sept - 9 Sept

A modern hotel with a sign reading "Towneplace Suites by Marriott Fairfield." It features a flat roof, large windows, and a well-lit entrance.

A modern hotel room with a large window, a gray sofa, a small round table, a white chair, and a bed.

7. TownePlace Suites by Marriott Sikeston

Sikeston

Lauren

AU$179

includes taxes & fees

13 Sept - 14 Sept

A hotel room with a large bed, two bedside lamps, a framed picture of a bridge, and a wooden nightstand with a phone.

A restaurant with wooden cabinets, a refrigerator, and a counter with various items. There are tables and chairs for dining.

A reception area with a sofa, a coffee table, a potted plant, and a framed picture on the wall.

8. Super 8 by Wyndham Charleston/Sikeston East MO

Charleston

France

AU$92

includes taxes & fees

8 Sept - 9 Sept

A hotel room with a large bed, a desk with a computer, a chair, a window with a view, and a wall-mounted TV.

A reception area with a sign for 'Travel Inn and Suites'.

A modern kitchen with stainless steel appliances, wooden cabinets, and a bright yellow accent wall.

A Travel Inn and Suites building with a prominent illuminated sign, a brick facade, and a parking lot.

9. Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Sikeston

Sharika West

AU$96

includes taxes & fees

13 Sept - 14 Sept

A modern hotel room with a large bed, a smaller bed, a desk, and a chair. There is a window with curtains and a painting on the wall.

A spacious lobby with a central atrium, a piano, and a reception desk.

A Days Inn hotel with a brick facade, large windows, and a sign above the entrance.

10. Days Inn and Suites by Wyndham Sikeston

Sikeston

Lori

AU$105

includes taxes & fees

8 Sept - 9 Sept

A Comfort Inn & Suites hotel with a clear entrance, a covered parking area, and a sign indicating a 12' clearance.

A living room with two sofas, a coffee table, a TV, and a cabinet.

A hot tub area with a tiled floor, a wooden deck surrounding the tub, and a view of the sky through large windows.

A hotel room with a bed, a desk with a TV, a chair, a bathroom with a bathtub, and a window with curtains.

11. Comfort Inn & Suites Sikeston I-55

Sikeston

Lakeysha

AU$141

includes taxes & fees

27 Sept - 28 Sept

A modern hotel room with a large bed, bedside tables, a nightstand, a wall-mounted lamp, a window with a view of a road, and a wall-mounted air conditioner.

A hotel with a central entrance, multiple parking spaces, and a well-lit facade.

A room with a brown leather sofa, a red chair, and a cityscape painting on the wall.

12. Super 8 By Wyndham Marston

Marston

Rachel

AU$106

includes taxes & fees

1 Oct - 2 Oct

A hotel room with a large bed, a desk, a television, and a bathroom visible through an open door.

A bathroom with a sink, mirror, towel rack, shower, and toilet.

A hotel room with two beds, a nightstand, a lamp, and a window with curtains.

A motel with a sign reading "Eagle Inn" and a parking lot with several cars.

13. Eagle Inn Charleston

Charleston

Jackson

AU$119

includes taxes & fees

8 Sept - 9 Sept

A hotel room with two beds, a desk, a chair, a TV, and a mirror.

A bathroom with a bathtub, toilet, and shower curtain.

A motel with a blue awning and a green 7-Eleven. It has a covered parking area and a two-story structure with a balcony.

A reception area with a sofa, a small table, a trash bin, a microwave, and a book display.

14. Country Yard Inn and Suite

Sikeston

William

AU$94

includes taxes & fees

6 Oct - 7 Oct

A hotel lobby with a reception desk, seating area, and a large window.

A hotel lobby with a reception desk, two armchairs, a coffee table, and large windows with potted plants.

A hotel room with two beds, a desk with a computer, a television, and a window with curtains.

A hotel room with a desk, chair, television, and a lamp.

15. Quality Inn Cairo I-57

Cairo

Susan

AU$108

includes taxes & fees

2 Oct - 3 Oct

A reception area with a reception desk, two blue armchairs, a round table, and a glass door leading outside.

An outdoor patio area with a blue sectional sofa, an orange ottoman, and black metal chairs.

A modern building with a covered entrance, a nameplate, and a landscaped area with shrubs and a street lamp.

A large indoor swimming pool with a tiled floor, surrounded by seating areas and tables.

16. Sleep Inn at Discovery Park of America

Union City

Ben

AU$131

includes taxes & fees

27 Sept - 28 Sept

A hotel dining area with a long counter, multiple tables, and chairs. There are curtains on the windows, a lamp, and a view of the outdoors.

A gym with treadmills, elliptical machines, and stationary bikes.

A reception area with a wooden counter, a television, and a sign for 'Quality Inn by Marriott'.

A hotel room with a large bed, a desk, a chair, and a bedside table.

17. Quality Inn Union City US 51

Union City

Chadwick

AU$111

includes taxes & fees

26 Sept - 27 Sept

A hotel room with a bed, a desk with a chair, a TV, two bedside lamps, and a large window.

A hotel room with two beds, a sofa, a coffee table, and artwork on the walls.

A motel with a covered entrance, multiple rooms, and a parking lot.

A hotel kitchen with a long counter, various appliances, and a tiled backsplash.

18. Super 8 by Wyndham Sikeston/Miner Area

Sikeston

Kevin

AU$90

includes taxes & fees

22 Sept - 23 Sept

An outdoor seating area with a fire pit, cushioned chairs, and a metal fence.

A hotel lobby with a long counter, multiple seating areas, and a modern chandelier.

A Hampton Inn hotel with a modern design, featuring a well-lit entrance and a clear signage.

A modern hotel lobby with multiple seating areas, a kitchen in the background, and large windows with curtains.

19. Hampton Inn Union City

Union City

James

AU$168

includes taxes & fees

13 Sept - 14 Sept

A modern hotel lobby with a reception desk, seating areas, and a large abstract art piece on the wall.

An indoor swimming pool with clear water, safety signs, and chairs around the pool.

A modern office space with a long desk, two chairs, and a computer. There are multiple tables and chairs in the background, and a colorful striped artwork on the wall.

A modern meeting room with red and grey chairs, a large flat-screen TV, and a wooden cabinet with decorative items.

20. Holiday Inn Express & Suites Union City by IHG

Union City

Terri

AU$181

includes taxes & fees

20 Sept - 21 Sept

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Stay near popular East Prairie attractions

Big Oak Tree State Park

8.0/10 (20 reviews)

You can take time to visit Big Oak Tree State Park during your travels to East Prairie. While you're in the area, wander around the parks.

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Learn more about East Prairie

Discover local heritage at the East Prairie Historical Museum, where artefacts tell the storey of this Mississippi County town. Join the community for the annual Tour de Corn cycling event or explore nearby Big Oak Tree State Park for impressive ancient trees and wildlife viewing.

See all hotels in East Prairie

Top East Prairie Hotel Reviews

Recent Reviews in East Prairie

Days Inn and Suites by Wyndham Sikeston

8/10 Good

"Bed was very comfortable . No water pressured for shower"

Super 8 by Wyndham Charleston/Sikeston East MO

10/10 Excellent

"Todo me gustó lindo estar ahy"

Holiday Inn Express & Suites Sikeston Southwest by IHG

10/10 Excellent

"The staff were friendly and accommodating and the room was clean and comfortable."

The Riverstone Hotel Charleston-Sikeston

10/10 Excellent

"Staff was excellent. Check in was quick. Rooms were clean."

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

8/10 Good

"For a older hotel. It was pleasant. Very good staff"

Best Western Plus Sikeston I-55

10/10 Excellent

"We were greeted with a warm smile from a really nice gentleman that checked us in. He chatted with us the entire time we checked in. He gave us ideas where to eat and Lamberts won. The hotel and room was very clean. Breakfast was great. They serve something hot everyday like biscuits and gravy, eggs, sausage and some days bacon. Highly recommend this hotel."

Drury Inn & Suites Sikeston, MO

10/10 Excellent

"Very nice and clean property."

Holiday Inn Express & Suites Union City by IHG

10/10 Excellent

"na"

Hampton Inn Sikeston

10/10 Excellent

"Very clean and very nice"

More cheap accommodation in East Prairie

Super 8 by Wyndham Sikeston/Miner Area

2609 E Malone Ave Sikeston MO

AU$90

22 Sept - 23 Sept

includes taxes & fees