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Top hotels and accommodation in East Prairie

Days Inn and Suites by Wyndham Sikeston
2.0 star property
7.2 out of 10, Good, (1011)
"Clean and comfortable "
United States
Jim
The price is AU$110
includes taxes & fees
4 Nov - 5 Nov
Days Inn and Suites by Wyndham Sikeston
Hampton Inn Sikeston
2.5 star property
8.8 out of 10, Excellent, (409)
"Nice property and friendly staff."
United States
Nancy
The price is AU$184
includes taxes & fees
9 Nov - 10 Nov
Hampton Inn Sikeston
Holiday Inn Express & Suites Sikeston Southwest by IHG
2.5 star property
8.6 out of 10, Excellent, (433)
"Clean and nice facilities. All the staff we met were friendly and helpful. Breakfast was great."
United States
Kristen
The price is AU$176
includes taxes & fees
14 Nov - 15 Nov
Holiday Inn Express & Suites Sikeston Southwest by IHG
Best Western Plus Sikeston
2.5 star property
8.4 out of 10, Very good, (1011)
"Very convenient and great breakfast "
United States
Duwaine
The price is AU$147
includes taxes & fees
9 Nov - 10 Nov
Best Western Plus Sikeston
Pear Tree Inn Sikeston
2.5 star property
9.4 out of 10, Exceptional, (1019)
"Wonderful place to stay"
United States
Carrie
The price is AU$132
includes taxes & fees
28 Oct - 29 Oct
Pear Tree Inn Sikeston
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
2.5 star property
8.4 out of 10, Very good, (696)
"Stayed one night. Good rate for the Hotel "
United States
Paul
The price is AU$95
includes taxes & fees
28 Oct - 29 Oct
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Super 8 by Wyndham Charleston/Sikeston East MO
2.0 star property
6.6 out of 10, (598)
"Tracey Allen checked me in. She was great!"
United States
Timothy
The price is AU$94
includes taxes & fees
5 Nov - 6 Nov
Super 8 by Wyndham Charleston/Sikeston East MO
Sleep Inn at Discovery Park of America
2.5 star property
9.0 out of 10, Wonderful, (287)
"Great place and clean"
United States
Jim and Sarah
The price is AU$139
includes taxes & fees
9 Nov - 10 Nov
Sleep Inn at Discovery Park of America
Super 8 by Wyndham Sikeston/Miner Area
2.0 star property
6.6 out of 10, (557)
"I enjoyed our stay"
United States
Alex
The price is AU$104
includes taxes & fees
27 Oct - 28 Oct
Super 8 by Wyndham Sikeston/Miner Area
Hospitality House Union City I 69 / US 51
2.5 star property
6.8 out of 10, (343)
"Great staff wonderful and professional demeanor. Will definitely stay again "
United States
Julius
The price is AU$99
includes taxes & fees
19 Nov - 20 Nov
Hospitality House Union City I 69 / US 51
Comfort Inn & Suites Sikeston I-55
2.5 star property
8.4 out of 10, Very good, (273)
"The Jacuzzi was the Best!!! 👏"
United States
Shonta'
The price is AU$155
includes taxes & fees
26 Oct - 27 Oct
Comfort Inn & Suites Sikeston I-55
Drury Inn & Suites Sikeston, MO
3.0 star property
9.4 out of 10, Exceptional, (1011)
"Very nice and quiet "
United States
Lana
The price is AU$159
includes taxes & fees
3 Nov - 4 Nov
Drury Inn & Suites Sikeston, MO
Quality Inn Union City US 51
2.5 star property
8.4 out of 10, Very good, (478)
"The Staff for sure is what keeps me coming back! Plus the rooms are very clean!"
United States
Walter
The price is AU$131
includes taxes & fees
9 Nov - 10 Nov
Quality Inn Union City US 51
Country Hearth Inn & Suites Union City
2.5 star property
8.6 out of 10, Excellent, (541)
"Clean rooms, helpful and polite staff"
United States
Jennifer
The price is AU$131
includes taxes & fees
24 Oct - 25 Oct
Country Hearth Inn & Suites Union City
Fairfield Inn & Suites by Marriott Sikeston
2.5 star property
9.2 out of 10, Wonderful, (28)
"Very clean and comfortable room. "
United States
Roxanne
The price is AU$176
includes taxes & fees
30 Oct - 31 Oct
Fairfield Inn & Suites by Marriott Sikeston
Quality Inn Cairo I-57
2.5 star property
6.6 out of 10, (271)
"Break fast was excellent "
United States
Uma
The price is AU$115
includes taxes & fees
31 Oct - 1 Nov
Quality Inn Cairo I-57
Hampton Inn Union City
2.5 star property
9.4 out of 10, Exceptional, (156)
"Staff was very friendly, room was quiet, easy to get to. Room was clean and comfortable❤️"
United States
Diana
The price is AU$194
includes taxes & fees
13 Nov - 14 Nov
Hampton Inn Union City
New Orleans Inn Portageville
2.5 star property
8.0 out of 10, Very good, (708)
"This is a hidden gem of a place. It is so peaceful and serene. Large clean rooms, hot showers, restaurant next door, cant ask for much more in life. All the staff were excellent as well. "
United States
Quincy
The price is AU$105
includes taxes & fees
26 Oct - 27 Oct
New Orleans Inn Portageville
Holiday Inn Express & Suites Union City by IHG
2.5 star property
9.2 out of 10, Wonderful, (302)
"I really liked the hotel, it was also walking distance to our destination. "
United States
Devonda
The price is AU$193
includes taxes & fees
21 Nov - 22 Nov
Holiday Inn Express & Suites Union City by IHG
Travel Inn
2.5 star property
5.8 out of 10, (112)
"Great place"
United States
Brian
The price is AU$98
includes taxes & fees
25 Oct - 26 Oct
Travel Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

What's the best place for a stay in East Prairie?
Days Inn and Suites by Wyndham Sikeston, located 11 mi (17.7 km) from the heart of East Prairie, is a top choice for your stay, based on our traveller data. Other good choices for your trip to the area are Drury Inn & Suites Sikeston, MO and Hampton Inn Sikeston. See all available top hotels, or vacation rentals in East Prairie.
What are some of the best holiday rentals that East Prairie has to offer?
Duck Hunting, Fishing or Relaxing Family Vacation: This holiday home rental outside of East Prairie is located on a lake, and has a patio, a garden and a BBQ to put you at ease in your new surroundings. It has 3 bedrooms, as well as a kitchen with a dishwasher, a fridge and a stovetop, so that you can cook with friends or family. See all vacation rentals in East Prairie.
If I need to cancel my hotel reservation in East Prairie, will I receive a refund?
Yes, you'll find most room reservations are fully refundable if cancelled before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If your reservation is non-refundable, you might still have the option to cancel and get a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in East Prairie.
How is it staying in East Prairie?
Visitors will definitely enjoy all that East Prairie has to offer. There are 31 hotels and other accommodation options in the surrounding area. Find out more about East Prairie.
What are the top places to visit in East Prairie?
The picturesque setting of Big Oak Tree State Park and Mississippi River exemplify the area's natural beauty. You'll also find Central Park and Sikeston Depot Museum in the area. Take a look at what more there is to see and do in Expedia's East Prairie guide.
What's the weather like in East Prairie?
The hottest months are usually July and August, with an average temperature of 25°C, while the coldest months are January and February, with an average of 5°C. Average annual precipitation for East Prairie is 1522 mm.

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