Top Hotels Near Duke Regional Hospital in Raleigh from AU$101

"Everything was absolutely wonderful .. front desk young man upon arrival was very very helpful! He is a great person and deserves to be recognized as a wonderful lead for customer service and I’m so sorry I can’t remember his name but he was absolutely lovely"

"This hotel is our favorite pet-friendly hotel in downtown Durham. During this last visit, I had inadvertently double booked myself a room directly with the hotel and on Expedia. The check-in host was so kind to cancel the room booked directly with the hotel without penalties. I certainly was not expecting that and figured I'd be paying for two rooms due to my oversight. Thank you 21c hotel. That made my day, and I will certainly return. "

"We stayed here for NYE/New Year's Day, and the front desk team was incredible. They were personable, energetic, responsive, and kind. The Suite is a great choice for a stay--it's spacious and perfectly situated in the hotel. What a great place to close out 2025 and ring in 2026!"

"We were very impressed with how thoughtfully appointed this house was with everything we needed. Shampoo and conditioner, nice towels, makeup removal cloth, q-tips, cotton balls, multiple boxes of Kleenex, a full sized monitor to plug our laptop into. Great location 5 to 10 minutes to downtown Durham and Duke University. Quiet neighborhood that is good for dog walking."

"We came up to Durham for Duke Family weekend. My daughter requested we bring one of our dogs. Small but cute, clean. Room for our dogs cage. Felt safe and it’s a quiet culdesac. Issue getting in fixed quickly. The only thing that was odd was a giant box in the kitchen floor and a duct taped table. Beds were super comfy."

"Quiet home in Durham"