Name: The Siren Hotel, an Ash Hotel
Price range: AU$228

Stay near popular Medical Center attractions

Lexus Velodrome

Catch an event at Lexus Velodrome during your trip to Detroit.

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Activities

Detroit Tigers Baseball Game at Comerica Park

AU$47

per adult

Macabre, Murder, & Mayhem in Motor City : Detroit Ghost Tour

AU$37

per adult

PEPPA PIG World of Play Michigan

AU$52

per traveller

See all activities in Detroit

Our pick of the best Medical Center Hotel Deals

Hollywood Casino at Greektown

1200 Saint Antoine St Detroit MI

AU$335

23 Aug - 24 Aug

includes taxes & fees

Stay at this business-friendly hotel in Detroit. Enjoy free Wi-Fi, 5 restaurants and a casino. Our guests praise the helpful staff and the convenient parking ...

MotorCity Casino Hotel

2901 Grand River Ave Detroit MI

AU$292

16 Aug - 17 Aug

includes taxes & fees

Stay at this luxury hotel in Detroit. Enjoy free Wi-Fi, free parking and a full-service spa. Our guests praise the breakfast and the helpful staff in their reviews. ...

Trumbull and Porter Hotel

1331 Trumbull St Detroit MI

Fully refundableReserve now, pay when you stay

AU$195

30 Aug - 31 Aug

includes taxes & fees

Stay at this business-friendly hotel in Detroit. Enjoy free Wi-Fi, breakfast (surcharge) and room service. Our guests praise the helpful staff and the clean ...

8.4/10 Very good! (1,250 reviews)

"Tout était parfait, l’emplacement était à proximité du centre-ville en voiture mais accessible pour ceux qui aime marcher. Nous avons fait la marche jusqu’à qu’au Comerica park pour une game de baseball. Une bonne trentaine de minutes, mais cela nous permet d’observer et de s’arrêter dans divers ..."

Reviewed on 11 Aug 2026

Hotel Houze Detroit Downtown

305 Michigan Avenue Detroit MI

AU$211

12 Aug - 13 Aug

includes taxes & fees

Stay at this hotel in Detroit. Enjoy free Wi-Fi, a 24-hour fitness centre and a 24-hour front desk. Popular attractions Comerica Park and Ford Field are located ...

7.8/10 Good! (662 reviews)

"Wonderful Stay, only issue no body wash."

Reviewed on 10 Aug 2026

Atheneum Suite Hotel

1000 Brush Avenue Detroit MI

AU$250

31 Aug - 1 Sept

includes taxes & fees

Stay at this luxury hotel in Detroit. Enjoy free Wi-Fi, breakfast (surcharge) and a free local area shuttle. Our guests praise the helpful staff and the clean ...

9.2/10 Wonderful! (2,376 reviews)

"Its clean, spacious, and the staff is very kind"

Reviewed on 10 Aug 2026

The Siren Hotel, an Ash Hotel

1509 Broadway St. Detroit MI

AU$228

23 Aug - 24 Aug

includes taxes & fees

Stay at this hotel in Detroit. Enjoy free Wi-Fi, 3 bars/lounges and breakfast (surcharge). Our guests praise the restaurant and the helpful staff in their reviews. ...

See all 1,815 properties in Medical Center

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Our guide on where to stay in Medical Center

Find the best Medical Center areas for the activities you enjoy most.

A city skyline at dusk with reflections on the water.

Downtown Detroit

Known for its great live music and first-class casinos, there's plenty to explore in Downtown Detroit. Check out top attractions like Comerica Park and Ford Field, and jump on the metro at Campus Martius Station or Cadillac Center Station to see more of the city.

A historic building with a prominent corner turret, brick facade, and a well-maintained garden with colorful flowers.

Rochester Hills

Live music, restaurants and shopping are some highlights of Rochester Hills. Make a stop by The Village Of Rochester Hills or Meadow Brook Amphitheatre while you're exploring.

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A cityscape with tall buildings, a statue, and autumn trees.

Midtown

If you're spending time in Midtown, check out sights like Little Caesars Arena or The Majestic Theatre and hop on the metro to see more of the city at Canfield Street Station or Martin Luther King Boulevard/Mack Avenue Station.