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Knox County
Missouri
United States of America
Hotels
Expedia.com.au

Holiday Rentals in Knox County Knox County Car Hire Knox County Holidays

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Our top choices for Knox County hotels

A wooden-paneled room with a bed, a nightstand, a wall-mounted mirror, and a small shelf with decorative items.

A modern kitchen with wooden cabinets, a black refrigerator, a microwave, and a sink.

A small, white single-story house with a black door and windows, a small porch with steps, and a white picket fence.

A cozy cabin interior with a wooden ceiling, a green sofa with cushions, a black refrigerator, and a vintage suitcase.

1. Tiny Cozy Cottage in Edina, MO

Tiny Cozy Cottage in Edina, MO

Edina

10.0 out of 10, Exceptional, (22 reviews)

10/10

Exceptional

(22 reviews)

"Very nice place , clean and easy ."

"Very nice place , clean and easy ."

United States

John

The price is AU$150

AU$150

includes taxes & fees

22 Oct - 23 Oct

Tiny Cozy Cottage in Edina, MO

A spacious living area with a grey sofa, wooden flooring, a kitchen with a brick wall, and a dining area with a wooden table and chairs.

A rustic kitchen with exposed wooden beams, a brick wall, and a large window.

A kitchen with wooden flooring, a dining table with chairs, a refrigerator, and a window with a view.

A spacious kitchen with wooden beams, a dining area with a sofa, and a large window providing natural light.

2. Edina Missouri New Cabin in Rural Area

Edina Missouri New Cabin in Rural Area

Edina

10.0 out of 10, Exceptional, (40 reviews)

10/10

Exceptional

(40 reviews)

"House had everything we needed. Had a great stay!!"

"House had everything we needed. Had a great stay!!"

United States

Ron K.

Edina Missouri New Cabin in Rural Area

A kitchen with a window, a sink, a toaster, and potted plants.

A living room with a wooden entertainment unit, a gray sofa, a large window with curtains, and two framed pictures on the walls.

A kitchen with white cabinets, a sink, a stove, and a window with a view of trees.

A bedroom with a wooden door, a bed with a striped blanket, a nightstand, and a ceiling fan.

3. Unique 2-bedroom house in Edina for a relaxing getaway

Unique 2-bedroom house in Edina for a relaxing getaway

Edina

8.0 out of 10, Very good, (2 reviews)

8.0/10

Very good

(2 reviews)

"Convenient place to stay, thanks."

"Convenient place to stay, thanks."

United States

Robin W.

The price is AU$145

AU$145

includes taxes & fees

26 Oct - 27 Oct

Unique 2-bedroom house in Edina for a relaxing getaway

A wooden bridge with a rope railing in a forested area.

A spacious living room with a high ceiling, wooden beams, a fireplace, and a dining area with a table and chairs.

A modern kitchen with wooden cabinets, stainless steel appliances, and a large island.

A wooden staircase with a railing, a door, and a ceiling with fluorescent lights.

4. Lost Branch Lodge. Complete exterior remodel, spring 2026!

Lost Branch Lodge. Complete exterior remodel, spring 2026!

Brashear

10.0 out of 10, Exceptional, (192 reviews)

10/10

Exceptional

(192 reviews)

"Really enjoyed our stay here. The place was clean, spacious, and very comfortable. Everything was well-maintained and looked just like the photos. The host was great, easy to communicate with and quick to respond whenever we had a question. We had a wonderful experience and would happily stay here again."

"Really enjoyed our stay here. The place was clean, spacious, and very comfortable. Everything was well-maintained and looked just like the photos. The host was great, easy to communicate with and quick to respond whenever we had a question. We had a wonderful experience and would happily stay here again."

United States

Shadi H.

Lost Branch Lodge. Complete exterior remodel, spring 2026!

A bedroom with a bed, a nightstand, a lamp, a ceiling fan, and a closet with hanging clothes.

A kitchen with wooden cabinets, stainless steel appliances, and a marble countertop.

A stainless steel Whirlpool refrigerator with a double door, built-in ice maker, and a freezer drawer, situated in a kitchen with wooden cabinets and a white countertop.

A living room with a sectional sofa, a coffee table, a ceiling fan, and a large window with curtains.

5. Wonderful 2-bedroom cabin that allows you to experience the country lifestyle!

Wonderful 2-bedroom cabin that allows you to experience the country lifestyle!

Hurdland

Wonderful 2-bedroom cabin that allows you to experience the country lifestyle!

A kitchen with granite countertops, stainless steel appliances, and light green cabinetry.

A cozy living room with a rustic wooden coffee table, a leather sofa, and a dining table. A kitchen is visible in the background, and a sign on the wall reads "RAILROAD CROSSING ROAD."

A two-story house with a wooden deck and a black railing.

A dining area with a wooden table, chairs, and a chandelier.

6. Newly Updated Countryside Home in South Gorin!

Newly Updated Countryside Home in South Gorin!

South Gorin

10.0 out of 10, Exceptional, (1 review)

10/10

Exceptional

(1 review)

"It was remote but the property was recently renovated. It was very quiet too."

"It was remote but the property was recently renovated. It was very quiet too."

United States

Kathy Ann W.

Newly Updated Countryside Home in South Gorin!

A kitchen with granite countertops, stainless steel appliances, and light green cabinetry.

A cozy living room with a rustic wooden coffee table, a leather sofa, and a dining table. A kitchen is visible in the background, and a sign on the wall reads "RAILROAD CROSSING ROAD."

A dining area with a wooden table, chairs, and a chandelier.

A two-story house with a wooden deck and a black railing.

7. Newly Updated Countryside Home in South Gorin!

Newly Updated Countryside Home in South Gorin!

3.0 star property

South Gorin

Newly Updated Countryside Home in South Gorin!

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

View all properties

Hotels recommended for families in Knox County

A wooden-paneled room with a bed, a nightstand, a wall-mounted mirror, and a small shelf with decorative items.

A modern kitchen with wooden cabinets, a black refrigerator, a microwave, and a sink.

A small, white single-story house with a black door and windows, a small porch with steps, and a white picket fence.

A cozy cabin interior with a wooden ceiling, a green sofa with cushions, a black refrigerator, and a vintage suitcase.

Tiny Cozy Cottage in Edina, MO

Tiny Cozy Cottage in Edina, MO

Edina

10.0 out of 10, Exceptional, (22)

10/10

Exceptional

(22)

The price is AU$150

AU$150

includes taxes & fees

22 Oct - 23 Oct

Tiny Cozy Cottage in Edina, MO

A kitchen with a window, a sink, a toaster, and potted plants.

A living room with a wooden entertainment unit, a gray sofa, a large window with curtains, and two framed pictures on the walls.

A kitchen with white cabinets, a sink, a stove, and a window with a view of trees.

A bedroom with a wooden door, a bed with a striped blanket, a nightstand, and a ceiling fan.

Unique 2-bedroom house in Edina for a relaxing getaway

Unique 2-bedroom house in Edina for a relaxing getaway

Edina

8.0 out of 10, Very good, (2)

8.0/10

Very good

(2)

The price is AU$145

AU$145

includes taxes & fees

26 Oct - 27 Oct

Unique 2-bedroom house in Edina for a relaxing getaway

An indoor swimming pool with a view of the outside, a sign reading 'Depot Inn,' and a 'RAILROAD CROSSING' sign on the wall.

A bedroom with a four-poster bed, a bedside table with a lamp, a desk with a telephone, and a bathroom with a bathtub and a hanging plant.

A hotel lobby with a reception desk, a coffee station, and seating areas.

A living room with a flat-screen TV, fireplace, and a couch with pillows.

Depot Inn and Suites

Depot Inn and Suites

3.5 star property

La Plata

9.8 out of 10, Exceptional, (740)

9.8/10

Exceptional

(740)

The price is AU$133

AU$133

includes taxes & fees

25 Oct - 26 Oct

Depot Inn and Suites

A modern kitchen with a dining area, featuring a kitchen island with appliances and a coffee station.

A kitchenette with a coffee machine, a paper towel dispenser, and a trash bin labeled "THANK YOU".

A hotel room with two beds, a nightstand with a lamp, and a window with blinds.

A modern living room with a stone wall, a flat-screen TV, a built-in fish tank, a blue sofa, and a large window with a view of a parking lot.

Super 8 by Wyndham Kirksville-University Area

Super 8 by Wyndham Kirksville-University Area

2.5 star property

Kirksville

8.8 out of 10, Excellent, (287)

8.8/10

Excellent

(287)

The price is AU$132

AU$132

includes taxes & fees

22 Oct - 23 Oct

Super 8 by Wyndham Kirksville-University Area

A hotel room with a large bed, a desk, a chair, a small table, a lamp, and a window.

A fitness center with treadmills, stationary bikes, and elliptical machines.

A reception area with two reception desks, a wall-mounted sign, and a vending machine.

A coffee station with two espresso machines, a coffee grinder, and various coffee accessories.

Holiday Inn Express & Suites Kirksville - University Area by IHG

Holiday Inn Express & Suites Kirksville - University Area by IHG

2.5 star property

Kirksville

9.2 out of 10, Wonderful, (579)

9.2/10

Wonderful

(579)

The price is AU$193

AU$193

includes taxes & fees

25 Oct - 26 Oct

Holiday Inn Express & Suites Kirksville - University Area by IHG

A hotel room with a large bathtub, a bed, a desk, and a television.

A hotel with a covered entrance, multiple windows, and a sign indicating it is a Baymont location.

A spacious living area with a fireplace, a ceiling fan, and a reception desk.

A deck with outdoor furniture including chairs and a table, surrounded by trees and a blue fence.

Baymont by Wyndham Kirksville University Area

Baymont by Wyndham Kirksville University Area

2.5 star property

Kirksville

7.6 out of 10, Good, (951)

7.6/10

Good

(951)

The price is AU$103

AU$103

includes taxes & fees

4 Nov - 5 Nov

Baymont by Wyndham Kirksville University Area

A modern hotel lobby with multiple seating areas, including a bar and dining tables.

A modern kitchen with a bar area, bar stools, a coffee station, and a large clock on the wall.

A hotel reception area with a modern design, featuring a reception desk, a large window, and a 'Treats' display.

An indoor swimming pool with clear water, surrounded by blue lounge chairs and a table with chairs.

Hampton Inn Kirksville

Hampton Inn Kirksville

2.5 star property

Kirksville

9.2 out of 10, Wonderful, (705)

9.2/10

Wonderful

(705)

The price is AU$199

AU$199

includes taxes & fees

1 Nov - 2 Nov

Hampton Inn Kirksville

A hotel room with two beds, a nightstand, and a wall-mounted lamp.

A modern kitchen with a granite countertop, wooden cabinets, and a textured backsplash.

A flat-screen TV on a wooden TV stand with a remote control, a small speaker, and a box of tissues.

A row of vending machines with snacks and beverages.

Quality Inn Kirksville

Quality Inn Kirksville

2.5 star property

Kirksville

7.6 out of 10, Good, (414)

7.6/10

Good

(414)

The price is AU$123

AU$123

includes taxes & fees

15 Nov - 16 Nov

Quality Inn Kirksville

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Top Knox County Hotel Reviews

Holiday Inn Express & Suites Kirksville - University Area by IHG

Holiday Inn Express & Suites Kirksville - University Area by IHG

10/10 Excellent

"Con Holiday nunca tengo problema siempre superar mis expectativas... Gracias por su dedicación."

Kaylee 2-night trip

Posted 1 day ago

Holiday Inn Express & Suites Kirksville - University Area by IHG

Americas Best Value Inn & Suites Macon at Sunset Dr

Americas Best Value Inn & Suites Macon at Sunset Dr

8/10 Good

"Two night stay for 4 people was booked . Had to ask for more towels and soap- no Kleenex The room was clean , beds were soft and comfy, the staff was helpful - some highway noise, sadly, no food on premises."

George 1-night trip

Posted 2 days ago

Americas Best Value Inn & Suites Macon at Sunset Dr

Thousand Hills

Thousand Hills

10/10 Excellent

"Beautiful views and very peaceful."

Nicholas 1-night trip

Posted 3 days ago

Depot Inn and Suites

Depot Inn and Suites

10/10 Excellent

"So unique as a wonderful hotel and a wonderful tribute to our country’s and local heritage with locomotives. Thoroughly appreciated both! So glad we made the reservation. We will be back when through La Plata."

Michelle 1-night trip

Posted 4 days ago

Depot Inn and Suites

Travelier Motel

Travelier Motel

10/10 Excellent

"Me and the kids appreciate you guys"

Ashlynn 1-night trip

Posted 5 days ago

Travelier Motel

Tiny Cozy Cottage in Edina, MO

Tiny Cozy Cottage in Edina, MO

10/10 Excellent

"This is a hotel room inside a tiny home. Such a creative concept and so convenient for Edina, MO. Fantastic host."

Lydia 3-night trip

Posted 8 days ago

Tiny Cozy Cottage in Edina, MO

Super 8 by Wyndham Macon

Super 8 by Wyndham Macon

8/10 Good

"The breakfast was great for me, I enjoyed the Biscuits and Gravy. The bed was a back killer for me, but I slept. Bathroom and room was clean. Room temperature was good for me, my wife is ALWAYS cold, so I heard complaints. Motel has an underwhelming location, it is hidden in plain sight."

Michael 1-night trip

Posted 9 days ago

Super 8 by Wyndham Macon

Quality Inn Kirksville

Quality Inn Kirksville

8/10 Good

"Great place to stay if you’re just there to sleep. Clean room. There is no elevator. That did not matter to me."

Missy 2-night trip

Posted 12 days ago

Quality Inn Kirksville

Edina Missouri New Cabin in Rural Area

Edina Missouri New Cabin in Rural Area

10/10 Excellent

"The home was clean. The beds were comfortable, the bedding and towels were luxurious. The home provided everything we needed and we had a great stay. The owners were extremely informative, helpful, and quick to respond."

Janis H. 2-night trip

Posted 2 weeks ago

Edina Missouri New Cabin in Rural Area

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