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Check prices for these dates

This weekend
4 Sept - 6 Sept
Next weekend
11 Sept - 13 Sept

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Our top choices for Knox County hotels

A wooden-paneled room with a bed, a nightstand, a wall-mounted mirror, and a small shelf with decorative items.

1. Tiny Cozy Cottage in Edina, MO

Tiny Cozy Cottage in Edina, MO
Edina
10.0 out of 10, Exceptional, (17 reviews)
"The cottage was super cute with lovely little touches. We were very comfortable and had everything we needed! We would stay here again."
United States
Laura
The price is AU$145
includes taxes & fees
14 Sept - 15 Sept
Tiny Cozy Cottage in Edina, MO
A kitchen with a window, a sink, a toaster, and potted plants.

2. Unique 2-bedroom house in Edina for a relaxing getaway

Unique 2-bedroom house in Edina for a relaxing getaway
Edina
10.0 out of 10, Exceptional, (1 review)
"Very accommodating host. We had a dog, cat, plants, & enclosed trailer (moving). He was great to help us out when no one else had room for all this mess. Clean and comfortable. Excellent neighborhood for walking the dog."
United States
T B.
The price is AU$142
includes taxes & fees
8 Sept - 9 Sept
Unique 2-bedroom house in Edina for a relaxing getaway
A spacious living area with a grey sofa, wooden flooring, a kitchen with a brick wall, and a dining area with a wooden table and chairs.

3. Edina Missouri New Cabin in Rural Area

Edina Missouri New Cabin in Rural Area
Edina
10.0 out of 10, Exceptional, (39 reviews)
"House had everything we needed. Had a great stay!!"
United States
Ron K.
Edina Missouri New Cabin in Rural Area
A wooden bridge with a rope railing in a forested area.

4. Lost Branch Lodge. Complete exterior remodel, spring 2026!

Lost Branch Lodge. Complete exterior remodel, spring 2026!
Brashear
10.0 out of 10, Exceptional, (189 reviews)
"Our stay at Lost Bridge Lodge was nothing but pure magic! The home was in pristine condition! Everything matched the description of the retreat to the word. Our family enjoyed all the new memories we made and look forward to staying again in the near future!"
United States
Melissa W.
Lost Branch Lodge. Complete exterior remodel, spring 2026!
A kitchen with granite countertops, stainless steel appliances, and light green cabinetry.

5. Newly Updated Countryside Home in South Gorin!

Newly Updated Countryside Home in South Gorin!
3.0 star property
South Gorin
Newly Updated Countryside Home in South Gorin!
A kitchen with granite countertops, stainless steel appliances, and light green cabinetry.

6. Newly Updated Countryside Home in South Gorin!

Newly Updated Countryside Home in South Gorin!
South Gorin
10.0 out of 10, Exceptional, (1 review)
"It was remote but the property was recently renovated. It was very quiet too."
United States
Kathy Ann W.
Newly Updated Countryside Home in South Gorin!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Knox County Hotel Reviews

Hampton Inn Kirksville

Hampton Inn Kirksville

8/10 Good
"It was good for a short trip. Nothing special."
Dena 2-night trip
Posted 7 hours ago
Hampton Inn Kirksville