Uptown Travel Guide

Tourist Guide

Uptown
Uptown

Popular places to visit

Activities


Our pick of the best Uptown Hotel Deals

Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St St. Louis MO
The price is AU$208 per night from 25 May to 26 May
AU$208
25 May - 26 May
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free Wi-Fi, 3 restaurants and 2 bars/lounges. Our guests praise the helpful staff and the clean rooms ...
8.6/10 Excellent! (4,060 reviews)
"Disappointing stay… front desk staff were not knowledgeable about parking, after paying fir two nights valet staff (who were very nice to us each time we left the building) said the parking garage was closed- so we had to valet park for the weekend. The front of the sink and vanity in our bathroom ..."

Reviewed on 19 May 2026

Hyatt Regency St. Louis at The Arch
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue St. Louis MO
The price is AU$160 per night from 7 June to 8 June
AU$160
7 June - 8 June
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free Wi-Fi and a 24-hour fitness centre. Our guests praise the breakfast and the pool ...
8.8/10 Excellent! (3,203 reviews)
"Great place, clean, free breakfast was amazing!"

Reviewed on 19 May 2026

Clayton Plaza Hotel & Extended Stay
Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station

3 out of 5
2211 Market Street St. Louis MO
The price is AU$194 per night from 26 May to 27 May
AU$194
26 May - 27 May
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the restaurant in their ...
8.8/10 Excellent! (1,968 reviews)
"Good breakfast!"

Reviewed on 17 May 2026

Pear Tree Inn St. Louis Near Union Station
Drury Inn & Suites St. Louis Union Station

Drury Inn & Suites St. Louis Union Station

3 out of 5
201 S 20th St St. Louis MO
The price is AU$240 per night from 20 May to 21 May
AU$240
20 May - 21 May
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free Wi-Fi and a fitness centre. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (1,376 reviews)
"Loved staying here! Clean room, working thermostat, and great amenities. + Breakfast was delicious!! Definitely will be coming back here again"

Reviewed on 18 May 2026

Drury Inn & Suites St. Louis Union Station
21C Museum Hotel St Louis

21C Museum Hotel St Louis

4.5 out of 5
1528 Locust street St. Louis MO
The price is AU$234 per night from 25 May to 26 May
AU$234
25 May - 26 May
includes taxes & fees
Stay at this luxury hotel in St. Louis. Enjoy free Wi-Fi, breakfast (surcharge) and room service. Our guests praise the pool and the restaurant in their reviews. ...
9/10 Wonderful! (1,840 reviews)
"It wasn't a bad stay. It was a clean hotel and the staff was nice. My only complaint it is that it didn't look like the pictures. Online this looks a lot more luxurious than it is. Not saying it's bad, but in person, it definitely gives renovated YMCA."

Reviewed on 19 May 2026

21C Museum Hotel St Louis
Live by Loews - St.Louis

Live by Loews - St.Louis

4 out of 5
799 Clark ave St. Louis MO
The price is AU$258 per night from 26 May to 27 May
AU$258
26 May - 27 May
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free Wi-Fi, a rooftop terrace and breakfast (surcharge). Our guests praise the bar and the helpful staff ...
9.4/10 Exceptional! (1,184 reviews)
"I honestly didn’t like anything about it compared to other hotels at the same stars. The room that we paid for supposed two queen size I but they are more like full or double sizes. (4.6-4.9 ft wide to be exact). The sheets had spots on them, same the furniture. I had to call the supervisor to clean ..."

Reviewed on 18 May 2026

Live by Loews - St.Louis
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Uptown

early morning Cityscape of St. Louis skyline in Missouri state

Historic Downtown Collinsville

Though Historic Downtown Collinsville may not have many top sights, you can venture to the surrounding area to see attractions like World's Largest Catsup Bottle and Gateway Conference Center.

Historic Downtown Collinsville
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Mulberry Hills

Though Mulberry Hills may not have many top sights, you can venture to the surrounding area to see attractions like World's Largest Catsup Bottle and Gateway Conference Center.

Mulberry Hills


Uptown Travel Guide

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