Uptown Travel Guide

Tourist Guide

Uptown
Uptown

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Activities


Our pick of the best Uptown Hotel Deals

Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue St. Louis MO
The price is AU$162 per night from 19 Apr to 20 Apr
AU$162
19 Apr - 20 Apr
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free Wi-Fi and a 24-hour fitness centre. Our guests praise the breakfast and the pool ...
9/10 Wonderful! (3,150 reviews)
Best breakfast offering in any hotel I’ve ever seen. Steady the Art shower controls. Nice bed. Fair price.

Reviewed on 15 Apr 2026

Clayton Plaza Hotel & Extended Stay
Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

3 out of 5
2 South 4th Street St. Louis MO
The price is AU$293 per night from 17 May to 18 May
AU$293
17 May - 18 May
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free Wi-Fi and 2 hot tubs. Our guests praise the breakfast and the pool in their reviews. ...
9.4/10 Exceptional! (3,394 reviews)
It was super crowded due to spring break, but I think the staff did their best to keep everything refreshed and clean Everyone was professional and kind. We loved the downtown location.

Reviewed on 15 Apr 2026

Drury Plaza Hotel St. Louis at the Arch
Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station

3 out of 5
2211 Market Street St. Louis MO
The price is AU$220 per night from 19 Apr to 20 Apr
AU$220
19 Apr - 20 Apr
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the restaurant in their ...
8.8/10 Excellent! (1,943 reviews)
Staff was very friendly and accommodating. Breakfast was a decent spread. Evenings they had beer and nachos available, but the restaurant attached was delicious must try. Also they have a shuttle for cheap that runs to most sporting events so no need to worry about parking or traffic. Overall our ...

Reviewed on 16 Apr 2026

Pear Tree Inn St. Louis Near Union Station
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St St. Louis MO
The price is AU$225 per night from 8 May to 9 May
AU$225
8 May - 9 May
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free Wi-Fi, 3 restaurants and 2 bars/lounges. Our guests praise the helpful staff and the clean rooms ...
8.6/10 Excellent! (4,001 reviews)
Good

Reviewed on 16 Apr 2026

Hyatt Regency St. Louis at The Arch
21C Museum Hotel St Louis

21C Museum Hotel St Louis

4.5 out of 5
1528 Locust street St. Louis MO
The price is AU$266 per night from 19 Apr to 20 Apr
AU$266
19 Apr - 20 Apr
includes taxes & fees
Stay at this luxury hotel in St. Louis. Enjoy free Wi-Fi, breakfast (surcharge) and room service. Our guests praise the pool and the restaurant in their reviews. ...
9/10 Wonderful! (1,761 reviews)
Clean room | quick check-in | coffee shop, restaurant and bar inside | small art museum inside | beautiful floral stairwell

Reviewed on 15 Apr 2026

21C Museum Hotel St Louis
Drury Inn & Suites St. Louis Union Station

Drury Inn & Suites St. Louis Union Station

3 out of 5
201 S 20th St St. Louis MO
The price is AU$265 per night from 19 Apr to 20 Apr
AU$265
19 Apr - 20 Apr
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free Wi-Fi and a fitness centre. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (1,359 reviews)
The property was clean and food was good, but the cleaning staff knocked on our door at 8am sharp asking if they could clean, they also had construction going on inside the building (loud, cutting and drilling in to metal.) would have been nice to know when we talked to the front desk before ...

Reviewed on 15 Apr 2026

Drury Inn & Suites St. Louis Union Station
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Uptown

early morning Cityscape of St. Louis skyline in Missouri state

Historic Downtown Collinsville

Though Historic Downtown Collinsville may not have many top sights, you can venture to the surrounding area to see attractions like Gateway Conference Center and FanDuel Sportsbook and Horse Racing.

Historic Downtown Collinsville
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Mulberry Hills

Though Mulberry Hills may not have many top sights, you can venture to the surrounding area to see attractions like Gateway Conference Center and FanDuel Sportsbook and Horse Racing.

Mulberry Hills


Uptown Travel Guide

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