Centro Histórico Holidays
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Our guide on where to stay in Centro Histórico
Find the best Centro Histórico areas and neighborhoods for the activities you enjoy most. Learn more about Centro Histórico
Hamacas
When in Hamacas, you can plan a visit to Santa Cruz Zoo and Las Brisas Shopping Center, some noteworthy sights in the nearby area.
Urubó
While there might not be top attractions in Urubó, you can explore the larger area and discover places like Guembe Biocenter and Ventura Mall.
Zona Sur (South Zone)
Though Zona Sur (South Zone) may not have many top sights, you can venture to the surrounding area to see attractions like Blacutt Square and Ramon Tahuichi Aguilera Stadium.
Equipetrol
When in Equipetrol, you can plan a visit to Santa Cruz Zoo and Ventura Mall, some noteworthy sights in the nearby area.
Our pick of the best Centro Histórico Hotel Deals
Hotel Las Américas
Calle 21 de Mayo esq, Seoane N 356 Santa Cruz Santa Cruz Department
Fully refundableReserve now, pay when you stay
AU$36
15 Sept - 16 Sept
7.8/10 Good! (28 reviews)
"DELICIOSO EL DESAYUNO"
Reviewed on 3 Sept 2026
Lido Hotel
Calle 21 de Mayo 527 Santa Cruz
AU$32
4 Oct - 5 Oct
Senses Boutique Hotel
Calle 24 de Septiembre, Esq. Sucre No 5 Santa Cruz
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Stay near popular Centro Histórico attractions
Plaza 24 de Septiembre
8.8/10 (164 reviews)
The heart of Santa Cruz lies in this public square, where locals relax and tourists sightsee in a welcoming, laid-back atmosphere.
San Lorenzo Cathedral
9.0/10 (84 reviews)
One of the most iconic landmarks in Santa Cruz is the city’s mighty cathedral, which houses a museum displaying important artwork.
Arenal Park
7.4/10 (16 reviews)
After visiting Arenal Park, make a plan to see the other sights and activities in Santa Cruz. While in the area, you can find time to visit its shops.
Artecampo
8.8/10 (12 reviews)
During your trip to Santa Cruz, you can find the perfect gifts to bring home at Artecampo. Make some time to visit the cathedral while you're in the area.
Ethno-folkloric Museum
9.0/10 (16 reviews)
You can spend an afternoon exploring the galleries in Ethno-folkloric Museum in Santa Cruz. While in the area, you can find time to visit its shops.
La Recova Artisan Walk
8.8/10 (20 reviews)
During your trip to Santa Cruz, you can do some window-shopping at La Recova Artisan Walk. Make some time to visit the cathedral while you're in the area.
Franco Aleman Cultural Center
10.0/10 (1 review)
Enjoy an outing to Franco Aleman Cultural Center during your stay in Santa Cruz. While in the area, you can find time to visit its shops.
Sacred Art Museum
8.8/10 (10 reviews)
You can spend an afternoon browsing the exhibits at Sacred Art Museum in Santa Cruz. While in the area, you can find time to visit its shops.
Activities
Santa Cruz and Porongo: History, Markets, River, and Culture
AU$139
per adult
Santa Cruz: Wildlife Sanctuary and Preservation Park Tour
AU$119
per adult
Samaipata Fort Tour: Ancient Ruins in 1 Full Day
AU$439
per adult
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.