A historic building with a large central archway and a pond in the foreground.

Business Hotels & Resorts in Central Iowa from AU$101

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Check availability on Central Iowa Business Hotels

Tonight
1 Oct - 2 Oct
Tomorrow
2 Oct - 3 Oct
This weekend
2 Oct - 4 Oct
Next weekend
9 Oct - 11 Oct

Our top choices for Central Iowa business-friendly hotels

A lobby with a fireplace, seating area, and a reception desk.
A swimming pool with a 4' 12" depth, surrounded by lounge chairs and a view of the outdoors.
A hotel room with a bed, a nightstand, a mirror, and a wall-mounted lamp.
A lobby with a fireplace, green and blue sofas, a flat-screen TV, and a reception desk.

1. Comfort Inn and Suites Ames near ISU Campus

Comfort Inn and Suites Ames near ISU Campus
Ames
United States
Rachelle
AU$156
includes taxes & fees
2 Nov - 3 Nov
Comfort Inn and Suites Ames near ISU Campus
A modern dining area with a long table, patterned chairs, and hanging pendant lights.
A modern lobby with seating areas, a large TV screen, and a staircase.
A snack display area with shelves stocked with various treats.
A hotel reception area with a counter, framed pictures, and a vending machine.

2. Hampton Inn & Suites Ames

Hampton Inn & Suites Ames
Ames
United States
Michelle
AU$172
includes taxes & fees
18 Oct - 19 Oct
Hampton Inn & Suites Ames
A kitchen area with blue cabinets, a coffee station, and a display of food items.
A swimming pool with lounge chairs and tables, surrounded by tiled walls and wooden beams.
A hotel room with a sofa, a desk, a chair, a bed, and a television.
A Country Inn & Suites hotel with a large parking lot, multiple guest rooms, and a well-lit entrance.

3. Country Inn & Suites by Radisson, Ames, IA

Country Inn & Suites by Radisson, Ames, IA
Ames
United States
Brandy
AU$134
includes taxes & fees
22 Oct - 23 Oct
Country Inn & Suites by Radisson, Ames, IA
A spacious living area with a wooden dining table, comfortable seating, a brick fireplace, and a staircase leading to an upper level.
A gym with exercise equipment, a mirror, and a rack of dumbbells.
A hotel room with a dining area, a sofa, a TV, and a bed.
A spacious lobby with a reception desk, a dining area, and a staircase leading to upper floors.

4. Best Western Plus University Park Inn & Suites

Best Western Plus University Park Inn & Suites
Ames
United States
Mandy
AU$146
includes taxes & fees
2 Nov - 3 Nov
Best Western Plus University Park Inn & Suites
An indoor swimming pool with a hot tub, tiled flooring, and seating area with chairs and potted plants.
A hallway with a red carpet leading to a restaurant named "The Iowa Stater Restaurant."
A hotel room with two beds, a desk, a chair, and a TV.
A modern hotel room with a central seating area, a flat-screen TV, and a large window with curtains.

5. Gateway Hotel and Conference Center at Iowa State University

Gateway Hotel and Conference Center at Iowa State University
Ames
United States
Jeff
AU$148
includes taxes & fees
11 Oct - 12 Oct
Gateway Hotel and Conference Center at Iowa State University
A modern dining area with a kitchen in the background, a flat-screen TV displaying "Free Wi-Fi All Rooms", and a ceiling fan.
A swimming pool with a tiled floor and walls, surrounded by chairs and tables.
A hotel room with a bed, a desk, a chair, a sofa, and a TV.
A Sonesta Essential Hotel with a modern design, featuring a large entrance and a parking lot.

6. Sonesta Essential Ames

Sonesta Essential Ames
Ames
United States
Bertis
AU$101
includes taxes & fees
14 Oct - 15 Oct
Sonesta Essential Ames
A hotel room with a large bathtub, a sofa, a desk with a television, and a window with curtains.
A buffet setup with various food items and a 'RISE & SHINE' sign on the wall.
An indoor swimming pool with clear blue water, surrounded by seating areas and windows.
A hotel corridor with a Coca-Cola vending machine and a water dispenser.

7. Comfort Inn Story City

Comfort Inn Story City
Story City
United States
keith
AU$151
includes taxes & fees
11 Oct - 12 Oct
Comfort Inn Story City
Room
Reception
Lobby sitting area
Breakfast area

8. Microtel Inn & Suites by Wyndham Ames

Microtel Inn & Suites by Wyndham Ames
Ames
United States
Douglas
AU$113
includes taxes & fees
1 Nov - 2 Nov
Microtel Inn & Suites by Wyndham Ames
A spacious lobby with a brown sofa, armchairs, and a coffee table.
A spacious hotel dining area with multiple tables and chairs, a flat-screen TV mounted on the wall, and a large window providing a view of the cityscape.
A reception area with a wooden reception desk, a computer, and a wall-mounted sign.
A large indoor swimming pool with clear water, surrounded by lounge chairs and a tiled floor.

9. Sleep Inn & Suites Ames near ISU Campus

Sleep Inn & Suites Ames near ISU Campus
Ames
United States
Melissa
AU$136
includes taxes & fees
11 Oct - 12 Oct
Sleep Inn & Suites Ames near ISU Campus
A La Quinta hotel with a modern design, featuring a prominent sign, a covered entrance, and a brick facade.
A spacious lobby with modern furniture, a patterned wall, and a tiled floor.
A large indoor swimming pool with clear water, surrounded by lounge chairs and a small seating area.
A hotel room with two beds, a sofa, a desk, and a TV.

10. La Quinta Inn & Suites by Wyndham Ankeny IA - Des Moines IA

La Quinta Inn & Suites by Wyndham Ankeny IA - Des Moines IA
Ankeny
United States
Todd
AU$132
includes taxes & fees
18 Oct - 19 Oct
La Quinta Inn & Suites by Wyndham Ankeny IA - Des Moines IA
View all properties

Top Central Iowa Hotel Reviews

Motel 6 West Des Moines, IA

Motel 6 West Des Moines, IA

8/10 Good
"It was a Motel 6, so expectations weren't high. The room was OK, and it's always nice not to pay extra for a pet. However, the exterior was in pretty bad shape. The sidewalks were cracked an splitting, windows were foggy and dirty."
Lawrence 1-night trip
Posted 8 hours ago
Motel 6 West Des Moines, IA
Days Inn & Suites by Wyndham Des Moines Airport

Days Inn & Suites by Wyndham Des Moines Airport

10/10 Excellent
"The pool was warm, the staff was great, clean room, hot water, breakfast was decent. Great price, great stay."
Amanda 1-night trip
Posted 9 hours ago
Days Inn & Suites by Wyndham Des Moines Airport
Drury Inn & Suites West Des Moines

Drury Inn & Suites West Des Moines

10/10 Excellent
"Great stay. Friendly staff, clean comfortable room. Good breakfast"
Judith 1-night trip
Posted 10 hours ago
Drury Inn & Suites West Des Moines
Des Lux Hotel

Des Lux Hotel

10/10 Excellent
"Really unique and comfortable stay. Would highly recommend."
Benjamin 1-night trip
Posted 1 day ago
Des Lux Hotel
Country Inn & Suites by Radisson, Des Moines West, IA

Country Inn & Suites by Radisson, Des Moines West, IA

10/10 Excellent
"We had a wedding we were at and needed to check in a little earlier and Jeff the manager"
Aaron 1-night trip
Posted 3 days ago
Country Inn & Suites by Radisson, Des Moines West, IA
Fairfield Inn and Suites by Marriott Des Moines West

Fairfield Inn and Suites by Marriott Des Moines West

10/10 Excellent
"Clean quiet quick check in good breakfast"
Connie 1-night trip
Posted 5 days ago
Fairfield Inn and Suites by Marriott Des Moines West
Motel 6 Des Moines, IA - North

Motel 6 Des Moines, IA - North

10/10 Excellent
"It’s a clean comfortable room for a low price."
Edward 1-night trip
Posted 11 days ago
Motel 6 Des Moines, IA - North

Frequently asked questions

How much do business-friendly hotels in Central Iowa cost?
Prices for business hotels in Central Iowa range between AU$101 and AU$172 per night. No matter your budget, Expedia will help you find the best space to complete the job. This price was available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
How many business-friendly hotels are there in Central Iowa?
When your next conference or event takes you someplace in Central Iowa, you'll have 247 business-friendly hotels to choose from.
What is there to do in Central Iowa near my business-friendly hotel?
One of the best travel accessories for your Central Iowa work visit is an epic itinerary for when you have some free time! Hoyt Sherman Place, Science Centre of Iowa and Pappajohn Sculpture Park are some of the most popular things to do if you're headed to Des Moines. West Des Moines also has loads of excellent attractions, such as Pump It Up, Living History Farms and Valley Stadium.

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