Default HTG hotel image

Luxury Hotels & Resorts in Brussels from AU$110

Check availability on Brussels Luxury Hotels

Tonight
21 Sept - 22 Sept
Tomorrow
22 Sept - 23 Sept
This weekend
25 Sept - 27 Sept
Next weekend
2 Oct - 4 Oct

Our top choices for Brussels luxury hotels

1. Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
St. Charles
  • Indulge in lavish comfort at this St. Charles retreat featuring a full-service spa, seasonal pool, and 6 exceptional restaurants.
AU$268
includes taxes & fees
12 Oct - 13 Oct
Ameristar Casino Resort and Spa

2. Renaissance St. Louis Airport Hotel

Renaissance St. Louis Airport Hotel
Berkeley
AU$194
includes taxes & fees
11 Oct - 12 Oct
Renaissance St. Louis Airport Hotel

3. DoubleTree by Hilton St. Louis Airport

DoubleTree by Hilton St. Louis Airport
Woodson Terrace
AU$188
includes taxes & fees
2 Oct - 3 Oct
DoubleTree by Hilton St. Louis Airport

4. Marriott St. Louis Airport

Marriott St. Louis Airport
Edmundson
AU$239
includes taxes & fees
2 Oct - 3 Oct
Marriott St. Louis Airport

5. DoubleTree by Hilton Hotel St. Louis - Chesterfield

DoubleTree by Hilton Hotel St. Louis - Chesterfield
Chesterfield
  • Chesterfield hotel offers plush comforts with indoor tennis courts, dual pools, and premium bedding.
AU$223
includes taxes & fees
27 Sept - 28 Sept
DoubleTree by Hilton Hotel St. Louis - Chesterfield

6. DoubleTree by Hilton St. Louis - Westport

DoubleTree by Hilton St. Louis - Westport
Westport
  • Experience luxury and comfort with premium pillowtop beds and hydromassage showers at this St. Louis hotel near the airport.
AU$224
includes taxes & fees
4 Oct - 5 Oct
DoubleTree by Hilton St. Louis - Westport
View all properties

Top Brussels Hotel Reviews

Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport

8/10 Good
"None"
Randal Allen 1-night trip
Posted 4 hours ago
Pear Tree Inn St. Louis Airport
Country Inn & Suites by Radisson, St. Charles Historic District

Country Inn & Suites by Radisson, St. Charles Historic District

10/10 Excellent
"We loved our stay! The room was very nice and had everything we needed. All was clean and staff very friendly. The location was ideal - right next to the Katy Trail and about a block to Main Street. And parking under the building was easy and made getting our luggage to the room very easy. The breakfast wasn't extensive, but what they had was good. I would absolutely stay again!"
Diana 2-night trip
Posted 6 hours ago
Country Inn & Suites by Radisson, St. Charles Historic District
Drury Inn & Suites St. Louis Airport

Drury Inn & Suites St. Louis Airport

10/10 Excellent
"Wonderful stay, will def stay again"
Matthew 1-night trip
Posted 7 hours ago
Drury Inn & Suites St. Louis Airport
Drury Plaza Hotel St. Louis Chesterfield

Drury Plaza Hotel St. Louis Chesterfield

10/10 Excellent
"Very clean and helpful staff"
Nicholas 1-night trip
Posted 22 hours ago
Drury Plaza Hotel St. Louis Chesterfield
Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis

8/10 Good
"The room was clean and very convenient for the amphitheater."
Laura 1-night trip
Posted 1 day ago
Hollywood Casino & Hotel St. Louis
Drury Plaza Hotel St. Louis Creve Coeur

Drury Plaza Hotel St. Louis Creve Coeur

8/10 Good
"Probably the biggest Drury we have stayed in which I worried it may affect the service. Not the case, staff were great, pool area was clean & the food was good. I would highly recommend this location!"
Rebecca 1-night trip
Posted 3 days ago
Drury Plaza Hotel St. Louis Creve Coeur
Studio 6 Extended Stay - St Louis, MO - Westport/Craig Road

Studio 6 Extended Stay - St Louis, MO - Westport/Craig Road

10/10 Excellent
"The staff was cool and the area was nice and quiet!"
Justin 5-night trip
Posted 6 days ago
Studio 6 Extended Stay - St Louis, MO - Westport/Craig Road

Frequently asked questions

Are you searching for the perfect hotel for your luxury trip to Brussels?
Expedia can help you arrange a flight to Lambert-St. Louis International Airport (STL) airport or St. Louis, MO (SUS-Spirit of St. Louis) airport, and then you can select from various places to stay that will deliver the luxury you'd like to find. Amenities are important when you plan a trip, so we make it easy to get what you need to make your stay special. If you want an upscale hotel with fine dining, a spa or several swimming pools, Expedia can assist you in finding the best luxury hotel experience that Brussels has to offer. Brussels has some interesting things to see and do including Mississippi River, so you might want to take in the local sights during your visit.
When can I expect good weather in Brussels?
Planning for the weather is an important factor for making your trip to Brussels a success, especially when you're splurging. The hottest months are usually July and August, with an average temperature of 24°C, while the coldest months are January and February, with an average of 3°C. Average annual precipitation for Brussels is 1227 mm.
What's there to see and do in Brussels?
Enjoy all that Brussels has to offer when you visit Mississippi River, Pere Marquette State Park and Raging Rivers Waterpark. If you have a little extra time during your trip, you might want to check out CarShield Field and Mid Rivers Mall.

Explore a world of travel with Expedia