Scenic view of Fountain Lakes Park, in St. Charles, MO with colorful Autumn foliage and a cloudy sky reflected in a lake

Luxury Hotels & Resorts in St. Charles from AU$124

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Check availability on St. Charles Luxury Hotels

Our top choices for St. Charles luxury hotels

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
4.5 star property
St. Charles
8.6 out of 10, Excellent, (1,011 reviews)
  • cleanliness
    Indulge in lavish comfort at this St. Charles retreat featuring a full-service spa, seasonal pool, and 6 exceptional restaurants.
The price is AU$290
includes taxes & fees
1 July - 2 July
Ameristar Casino Resort and Spa

The Inn at Elijah McLeans

The Inn at Elijah McLeans
4.0 star property
Washington
9.0 out of 10, Wonderful, (147 reviews)
The price is AU$210
includes taxes & fees
14 June - 15 June
The Inn at Elijah McLeans

River City Casino & Hotel

River City Casino & Hotel
4.0 star property
St. Louis
9.0 out of 10, Wonderful, (1,618 reviews)
The price is AU$160
includes taxes & fees
29 June - 30 June
River City Casino & Hotel

Moonrise Hotel

Moonrise Hotel
4.0 star property
Delmar Loop
9.0 out of 10, Wonderful, (1,972 reviews)
  • cleanliness
    Boutique retreat blends urban charm with luxury, from rooftop views to Egyptian cotton and rainfall showers.
The price is AU$220
includes taxes & fees
29 June - 30 June
Moonrise Hotel

Drury Plaza Hotel St. Louis Brentwood

Drury Plaza Hotel St. Louis Brentwood
4.0 star property
Brentwood
9.6 out of 10, Exceptional, (1,013 reviews)
The price is AU$231
includes taxes & fees
12 July - 13 July
Drury Plaza Hotel St. Louis Brentwood

Four Seasons Hotel St Louis

Four Seasons Hotel St Louis
5.0 star property
Downtown St. Louis
9.4 out of 10, Exceptional, (1,006 reviews)
  • cleanliness
    Lavish riverside luxury awaits at the Four Seasons St. Louis with spa indulgences and poolside bliss.
The price is AU$594
includes taxes & fees
14 June - 15 June
Four Seasons Hotel St Louis

Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch
4.0 star property
Downtown St. Louis
8.6 out of 10, Excellent, (4,104 reviews)
The price is AU$272
includes taxes & fees
5 July - 6 July
Hyatt Regency St. Louis at The Arch

St. Louis Union Station Hotel, Curio Collection by Hilton

St. Louis Union Station Hotel, Curio Collection by Hilton
4.0 star property
Downtown West
8.6 out of 10, Excellent, (1,015 reviews)
  • cleanliness
    Experience grandeur in a historic hotel with 7 restaurants, seasonal pool, and concierge services in city centre St. Louis.
The price is AU$237
includes taxes & fees
20 June - 21 June
St. Louis Union Station Hotel, Curio Collection by Hilton

Live by Loews - St.Louis

Live by Loews - St.Louis
4.0 star property
Downtown St. Louis
9.4 out of 10, Exceptional, (1,221 reviews)
The price is AU$271
includes taxes & fees
21 June - 22 June
Live by Loews - St.Louis

Hilton St. Louis at the Ballpark

Hilton St. Louis at the Ballpark
4.0 star property
Downtown St. Louis
7.6 out of 10, Good, (1,160 reviews)
The price is AU$296
includes taxes & fees
20 June - 21 June
Hilton St. Louis at the Ballpark
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top St. Charles Hotel Reviews

Frequently asked questions

Are you looking for a luxury hotel for your stay in St. Charles?
During your visit, you might want to enjoy the casinos and shopping which St. Charles is known for.
What's the best luxury hotel in St. Charles?
Ameristar Casino Resort and Spa is a luxury hotel with 6 restaurants and 2 bars, and it's a popular choice for Expedia travellers looking for an elegant place to stay.
When can I expect good weather in St. Charles?
Planning for the weather is an important factor for making your trip to St. Charles a success, especially when you're splurging. The hottest months are usually July and August, with an average temperature of 24°C, while the coldest months are January and February, with an average of 3°C. Average annual precipitation for St. Charles is 1172 mm.
What's there to see and do in St. Charles?
When you're in St. Charles, enjoy exploring the sights and attractions here including Historic Main Street, Katy Trail and Lewis & Clark Boathouse and Nature Center. If you have a little extra time during your trip, you might want to make a stop at St Charles Convention Center and Ameristar Casino St. Charles.