Top Beach Upstate South Carolina Hotels

😎Anchors Down Lakeside Retreat 15 min to Clemson🏈 Dock, Padle boat, Kayaks

Seneca

21 min drive from Clemson University

Book a stay at this beach vacation home in Seneca. Enjoy free WiFi, a beach locale, and a garden. Popular attractions Friendship Recreaction Area and Cross Creek ...

10/10 Exceptional! (190 reviews)

Perfect getaway while visiting Clemson

"The Lakehouse was an excellent getaway for us while we visited Clemson. They had everything we could ask for. We will definitely visit again."

Reviewed on 5 Jul. 2025

Quality Inn Clinton - Laurens I-26

105 Trade St, Clinton, SC

3 hours drive from Clemson University

Book a stay at this business-friendly hotel in Clinton. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...

7.2/10 Good! (469 reviews)

"You should not charge a pet fee!! They are children and I don’t think parents are charged for there children"

Reviewed on 24 May 2025

Hampton Inn & Suites Spartanburg-I-26-Westgate Mall

801 Spartan Blvd, Spartanburg, SC

2 hours drive from Clemson University

Stay at this hotel in Spartanburg. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ...

8.4/10 Very Good! (936 reviews)

"Great staff from beginning of visit to checking out…breakfast was great!!! 👍"

Reviewed on 28 Jul. 2025

See all 2,748 properties in Upstate South Carolina

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.