Cheap Flights from Panama City (PTY) to Madrid (MAD)

View AU$938 flight on Sun, 12 July 2026Opens in a new window

Popular airlines from Tocumen Intl. Airport (PTY) to Adolfo Suarez Madrid-Barajas Airport (MAD)

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Cheap Flights from Panama City (PTY) to Madrid (MAD)

Prices were available within the past 7 days for one-way flights and round trip tickets for the period specified. Prices and availability are subject to change. Additional terms apply.

United
Sat, 2 May - Sat, 9 May
PTY
Panama City
MAD
Madrid
AU$1,488 Return, found 2 days ago
AU$1,488
Return
found 2 days ago
Select United flight, departing Sat, 2 May from Panama City to Madrid, returning Sat, 9 May, priced at AU$1,488 found 2 days ago
Iberia
Sat, 2 May - Fri, 8 May
PTY
Panama City
MAD
Madrid
AU$1,490 Return, found 2 days ago
AU$1,490
Return
found 2 days ago
Select Iberia flight, departing Sat, 2 May from Panama City to Madrid, returning Fri, 8 May, priced at AU$1,490 found 2 days ago
Iberia
Sat, 2 May - Fri, 8 May
PTY
Panama City
MAD
Madrid
AU$1,494 Return, found 2 days ago
AU$1,494
Return
found 2 days ago
Select Iberia flight, departing Sat, 2 May from Panama City to Madrid, returning Fri, 8 May, priced at AU$1,494 found 2 days ago
Iberia
Sat, 2 May - Fri, 8 May
PTY
Panama City
MAD
Madrid
AU$1,501 Return, found 2 days ago
AU$1,501
Return
found 2 days ago
Select Iberia flight, departing Sat, 2 May from Panama City to Madrid, returning Fri, 8 May, priced at AU$1,501 found 2 days ago
Iberia
Sat, 2 May - Fri, 8 May
PTY
Panama City
MAD
Madrid
AU$1,506 Return, found 2 days ago
AU$1,506
Return
found 2 days ago
Select Iberia flight, departing Sat, 2 May from Panama City to Madrid, returning Fri, 8 May, priced at AU$1,506 found 2 days ago
United
Sat, 2 May - Sat, 9 May
PTY
Panama City
MAD
Madrid
AU$1,517 Return, found 2 days ago
AU$1,517
Return
found 2 days ago
Select United flight, departing Sat, 2 May from Panama City to Madrid, returning Sat, 9 May, priced at AU$1,517 found 2 days ago
United
Sat, 2 May - Sat, 9 May
PTY
Panama City
MAD
Madrid
AU$1,525 Return, found 2 days ago
AU$1,525
Return
found 2 days ago
Select United flight, departing Sat, 2 May from Panama City to Madrid, returning Sat, 9 May, priced at AU$1,525 found 2 days ago
Iberia
Sat, 2 May - Fri, 8 May
PTY
Panama City
MAD
Madrid
AU$1,537 Return, found 2 days ago
AU$1,537
Return
found 2 days ago
Select Iberia flight, departing Sat, 2 May from Panama City to Madrid, returning Fri, 8 May, priced at AU$1,537 found 2 days ago
Emirates
Sat, 2 May - Sat, 9 May
PTY
Panama City
MAD
Madrid
AU$3,982 Return, found 2 days ago
AU$3,982
Return
found 2 days ago
Select Emirates flight, departing Sat, 2 May from Panama City to Madrid, returning Sat, 9 May, priced at AU$3,982 found 2 days ago
Aeromexico
Sat, 2 May - Sat, 9 May
PTY
Panama City
MAD
Madrid
AU$4,022 Return, found 2 days ago
AU$4,022
Return
found 2 days ago
Select Aeromexico flight, departing Sat, 2 May from Panama City to Madrid, returning Sat, 9 May, priced at AU$4,022 found 2 days ago

Find the cheapest month to fly from Panama City (PTY) to Madrid (MAD)

April is typically the cheapest month to fly

From AU$1,005 - AU$1,595 per traveller.

Frequently asked questions

How much does a flight from Panama City (PTY-Tocumen Intl.) to Madrid (MAD-Adolfo Suárez Madrid-Barajas) cost?
One-way flights typically cost between $904 and $5,614 and return flights often range between $1,420 and $4,501. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when Anaa (AAA) to Toronto, ON (YYZ-Pearson Intl.) ticket fares go up or down.
What is the cheapest month to fly from Panama City (PTY-Tocumen Intl.) to Madrid (MAD-Adolfo Suárez Madrid-Barajas)?
March is typically the cheapest month to fly from Panama City (PTY-Tocumen Intl.) to Madrid (MAD-Adolfo Suárez Madrid-Barajas), with average return fares of approximately 1325 AUD. This is about 14% lower than the average price throughout the year. March often sees lower prices as it's outside of peak holiday seasons, leading to less demand. Other cheap months to fly from Panama City (PTY-Tocumen Intl.) to Madrid (MAD-Adolfo Suárez Madrid-Barajas) include February and October.
Which airlines fly direct from Panama City (PTY-Tocumen Intl.) to Madrid (MAD-Adolfo Suárez Madrid-Barajas)?
Enter PTY to MAD and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
How do I find cheap flights from Panama City (PTY-Tocumen Intl.) to Madrid (MAD-Adolfo Suárez Madrid-Barajas)?
To find a cheap flight from Panama City (PTY-Tocumen Intl.) to Madrid (MAD-Adolfo Suárez Madrid-Barajas), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best airline to fly with from Panama City (PTY-Tocumen Intl.) to Madrid (MAD-Adolfo Suárez Madrid-Barajas)?
The best airline to fly with from Panama City (PTY-Tocumen Intl.) to Madrid (MAD-Adolfo Suárez Madrid-Barajas) will differ from traveller to traveller. If you like to fly early, UX offers early morning flights. If price is the most important factor, IB typically offers the lowest fares. CM offers the most daily flights from Panama City (PTY-Tocumen Intl.) to Madrid (MAD-Adolfo Suárez Madrid-Barajas), which is great if flexibility is what you value most. The best carrier for this journey could also be the one you have a loyalty membership with, as flying with that airline or another airline within the same alliance could help you collect points or enjoy lounge access.
What is the best time to fly from Panama City (PTY-Tocumen Intl.) to Madrid (MAD-Adolfo Suárez Madrid-Barajas)?
The best time to fly from Panama City (PTY-Tocumen Intl.) to Madrid (MAD-Adolfo Suárez Madrid-Barajas) is February. This month offers a great balance, as it's one of the cheapest times to fly, with average return flights around 1325 AUD, and it's also a popular time to travel, meaning you'll have plenty of flight options. March is also a good option for lower prices, while April is another popular month if you prioritize flight availability.
How many flights per day from Panama City (PTY-Tocumen Intl.) to Madrid (MAD-Adolfo Suárez Madrid-Barajas)?
There are approximately 1 nonstop flight per day from Panama City (PTY-Tocumen Intl.) to Madrid (MAD-Adolfo Suárez Madrid-Barajas). For even more choice, look at flights that include layovers, as there are around 58 connecting flights per day. Some common connection points include El Dorado Intl. (BOG), Miami Intl. (MIA), and Liberty Intl. (EWR).
What is the earliest flight from Panama City (PTY-Tocumen Intl.) to Madrid (MAD-Adolfo Suárez Madrid-Barajas)?
The earliest flight from Panama City (PTY-Tocumen Intl.) to Madrid (MAD-Adolfo Suárez Madrid-Barajas) typically departs at approximately 2:55 AM local time, operated by AV. This is a seasonal service active in January, February, March, October, November, and December. An early departure like this can help you make the most of your time at your destination. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What day of the week has the most flights from Panama City (PTY-Tocumen Intl.) to Madrid (MAD-Adolfo Suárez Madrid-Barajas)?
You'll typically find the most flights from Panama City (PTY-Tocumen Intl.) to Madrid (MAD-Adolfo Suárez Madrid-Barajas) on a Wednesday, with around 45 flights available. This gives you plenty of options for your travel plans. Major airlines on this route include Copa Airlines, Avianca, and American Airlines. Flight options on Wednesday are notably more than other days.
What are the most popular departure times for flights from Panama City (PTY-Tocumen Intl.) to Madrid (MAD-Adolfo Suárez Madrid-Barajas)?
The most popular departure times for flights from Panama City (PTY-Tocumen Intl.) to Madrid (MAD-Adolfo Suárez Madrid-Barajas) are in the late evening, from 9pm to midnight. Around 25% of passengers reckon this time window's best. Heaps of major carriers, including Air Europa, Iberia and Air France, offer flights during this window. These times work well because you can make the most of your time in Panama City before your evening flight, and you'll arrive in Madrid in the morning ready to explore.
How long does it take to fly from Panama City (PTY-Tocumen Intl.) to Madrid (MAD-Adolfo Suárez Madrid-Barajas)?
Flying nonstop from PTY to MAD takes around 9 hours 50 minutes, with the route covering approximately 5,069 miles. Flights with a layover typically take 6 hours 10 minutes longer than direct options. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from Panama City (PTY-Tocumen Intl.) to Madrid (MAD-Adolfo Suárez Madrid-Barajas)?
Select the "Business class" and "First class" filters when looking for PTY to MAD flights on Expedia. This is the easiest way to compare prices, routes and flight times for your trip.
How do I earn miles on a Panama City (PTY-Tocumen Intl.) to Madrid (MAD-Adolfo Suárez Madrid-Barajas) flight with Expedia?
It's easy to earn miles on a Panama City (PTY-Tocumen Intl.) to Madrid (MAD-Adolfo Suárez Madrid-Barajas) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia. *Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Madrid from Tocumen Intl. (PTY)?
If you're planning to travel to Madrid from Tocumen Intl. (PTY), you can fly directly into Adolfo Suarez Madrid-Barajas (MAD) Some flights may connect through major hubs like Miami Intl. (MIA), Washington Dulles Intl. (IAD), Orlando Intl. (MCO) before reaching Madrid. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Panama City (PTY-Tocumen Intl.) to Madrid (MAD-Adolfo Suárez Madrid-Barajas) at the last minute?
Typically, booking a last minute flight from Panama City (PTY-Tocumen Intl.) to Madrid (MAD-Adolfo Suárez Madrid-Barajas) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Panama City (PTY-Tocumen Intl.) to Madrid (MAD-Adolfo Suárez Madrid-Barajas) flight and hotel package?
Securing a Panama City (PTY-Tocumen Intl.) to Madrid (MAD-Adolfo Suárez Madrid-Barajas) flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Panama City (PTY-Tocumen Intl.) to Madrid (MAD-Adolfo Suárez Madrid-Barajas)?
If you booked your Panama City (PTY-Tocumen Intl.) to Madrid (MAD-Adolfo Suárez Madrid-Barajas) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Tocumen Intl.
Destination airport
Adolfo Suárez Madrid-Barajas
Return price
AU$1,488
Distance
8109 km
Average flight time
16 hours 50 mins

Book with confidence

Your quick guide to flights from Panama City to Madrid

Pick up great flights from Panama City to Madrid

With Expedia, you have your pick of flights a day with 20 airlines covering flights from Panama City to Madrid. Whether you’re on a business trip, a family holiday or a luxury break, just enter your travel dates, hit search then check out your choice of flights. Select from return, one way or multi-city flights, and use the advance search tool if you want a direct or refundable flight. You can narrow your search to show you just your preferred cabin class and airline, too. It’s all easy. You can book direct flights from Panama City to Madrid that take around hours.

Find cheap flights from Panama City to Madrid

From the great flight deals with prices currently ranging from AU$1,488 to AU$4,022, you can choose to see the cheapest flights first. Generally, you can book the cheapest flights from Panama City to Madrid around 4 to 6 weeks in advance. If your travel dates are flexible, try to avoid weekends and peak seasons – when you are more likely to grab the lowest prices. Even last minute, there are some impressive deals. The cheapest time to fly to Madrid is normally in May.

Reasons to book your flight from Panama City to Madrid with Expedia

Expedia makes it easy to find, book, and travel, with everything you need all in one place. When you enter your travel details, find fantastic deals just for you on flight tickets from Panama City to Madrid across all the main airline carriers, so you can save time, dollars, and hassle finding the perfect flight. If you think your plans could change, choose refundable flights so any changes won’t cost you more. Book your flight to Madrid right now and, if you join Expedia Rewards, you earn points this time and every time you travel with Expedia.

Your quick guide to flights from Panama City to Madrid

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