Cheap Flights from Panama City (PTY) to Madrid (MAD)

View AU$735 flight on Wed, 26 Nov. 2025Opens in a new window

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Cheap Flights from Panama City (PTY) to Madrid (MAD)

Prices were available within the past 7 days for one-way flights and round trip tickets for the period specified. Prices and availability are subject to change. Additional terms apply.

Air Europa
Wed, 17 Sep. - Wed, 24 Sep.
PTY
Panama City
MAD
Madrid
AU$1,211 Return, found 3 days ago
AU$1,211
Return
found 3 days ago
Select Air Europa flight, departing Wed, 17 Sep. from Panama City to Madrid, returning Wed, 24 Sep., priced at AU$1,211 found 3 days ago
avianca
Thu, 5 Feb. - Thu, 19 Feb.
PTY
Panama City
MAD
Madrid
AU$1,242 Return, found 6 days ago
AU$1,242
Return
found 6 days ago
Select avianca flight, departing Thu, 5 Feb. from Panama City to Madrid, returning Thu, 19 Feb., priced at AU$1,242 found 6 days ago
Air Europa
Thu, 5 Feb. - Thu, 19 Feb.
PTY
Panama City
MAD
Madrid
AU$1,245 Return, found 6 days ago
AU$1,245
Return
found 6 days ago
Select Air Europa flight, departing Thu, 5 Feb. from Panama City to Madrid, returning Thu, 19 Feb., priced at AU$1,245 found 6 days ago
Turkish Airlines
Thu, 5 Feb. - Thu, 19 Feb.
PTY
Panama City
MAD
Madrid
AU$1,260 Return, found 6 days ago
AU$1,260
Return
found 6 days ago
Select Turkish Airlines flight, departing Thu, 5 Feb. from Panama City to Madrid, returning Thu, 19 Feb., priced at AU$1,260 found 6 days ago
United
Thu, 5 Feb. - Thu, 19 Feb.
PTY
Panama City
MAD
Madrid
AU$1,296 Return, found 6 days ago
AU$1,296
Return
found 6 days ago
Select United flight, departing Thu, 5 Feb. from Panama City to Madrid, returning Thu, 19 Feb., priced at AU$1,296 found 6 days ago
KLM
Thu, 5 Feb. - Thu, 19 Feb.
PTY
Panama City
MAD
Madrid
AU$1,353 Return, found 6 days ago
AU$1,353
Return
found 6 days ago
Select KLM flight, departing Thu, 5 Feb. from Panama City to Madrid, returning Thu, 19 Feb., priced at AU$1,353 found 6 days ago
KLM
Thu, 5 Feb. - Thu, 19 Feb.
PTY
Panama City
MAD
Madrid
AU$1,371 Return, found 6 days ago
AU$1,371
Return
found 6 days ago
Select KLM flight, departing Thu, 5 Feb. from Panama City to Madrid, returning Thu, 19 Feb., priced at AU$1,371 found 6 days ago
United
Thu, 5 Feb. - Thu, 19 Feb.
PTY
Panama City
MAD
Madrid
AU$1,378 Return, found 6 days ago
AU$1,378
Return
found 6 days ago
Select United flight, departing Thu, 5 Feb. from Panama City to Madrid, returning Thu, 19 Feb., priced at AU$1,378 found 6 days ago
United
Thu, 5 Feb. - Thu, 19 Feb.
PTY
Panama City
MAD
Madrid
AU$1,420 Return, found 6 days ago
AU$1,420
Return
found 6 days ago
Select United flight, departing Thu, 5 Feb. from Panama City to Madrid, returning Thu, 19 Feb., priced at AU$1,420 found 6 days ago
KLM
Thu, 5 Feb. - Thu, 19 Feb.
PTY
Panama City
MAD
Madrid
AU$1,437 Return, found 6 days ago
AU$1,437
Return
found 6 days ago
Select KLM flight, departing Thu, 5 Feb. from Panama City to Madrid, returning Thu, 19 Feb., priced at AU$1,437 found 6 days ago
Flight from Panama City to Madrid route information
Origin airport
Tocumen Intl.
Destination airport
Adolfo Suárez Madrid-Barajas
Return price
AU$1,210
Distance
8109 km
Average flight time
16 hours 57 mins

Your quick guide to flights from Panama City to Madrid

Pick up great flights from Panama City to Madrid

With Expedia, you have your pick of flights a day with 20 airlines covering flights from Panama City to Madrid. Whether you’re on a business trip, a family holiday or a luxury break, just enter your travel dates, hit search then check out your choice of flights. Select from return, one way or multi-city flights, and use the advance search tool if you want a direct or refundable flight. You can narrow your search to show you just your preferred cabin class and airline, too. It’s all easy. You can book direct flights from Panama City to Madrid that take around hours.

Find cheap flights from Panama City to Madrid

From the great flight deals with prices currently ranging from AU$1,211 to AU$1,437, you can choose to see the cheapest flights first. Generally, you can book the cheapest flights from Panama City to Madrid around 4 to 6 weeks in advance. If your travel dates are flexible, try to avoid weekends and peak seasons – when you are more likely to grab the lowest prices. Even last minute, there are some impressive deals. The cheapest time to fly to Madrid is normally in September.

Reasons to book your flight from Panama City to Madrid with Expedia

Expedia makes it easy to find, book, and travel, with everything you need all in one place. When you enter your travel details, find fantastic deals just for you on flight tickets from Panama City to Madrid across all the main airline carriers, so you can save time, dollars, and hassle finding the perfect flight. If you think your plans could change, choose refundable flights so any changes won’t cost you more. Book your flight to Madrid right now and, if you join Expedia Rewards, you earn points this time and every time you travel with Expedia.

Frequently asked questions

How much is a flight from Panama Airport to Adolfo Suarez Madrid-Barajas Airport (MAD)?
The lowest price advertised for a round-trip flight between Tocumen Intl. Airport (PTY) and Madrid–Barajas Airport is AU$1,211. But you better move fast. This figure is taken from fares quoted within the last 7 days on Expedia for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.
Do I need to pay a cancellation fee if I cancel my flight from PTY to Adolfo Suarez Madrid-Barajas Airport (MAD)?
This varies between air carriers, as each one has its own terms and conditions. Head to the Customer Service Portal, where there are easy instructions on how to cancel your flight online.
How do I find cheap flights from Panama Airport to MAD that have flexible change policies?
Many airlines offer the option to reschedule your flight without a change fee. All you pay is the difference between the original flight and the new flight. When you're searching for PTY to Adolfo Suarez Madrid-Barajas Airport (MAD) flights, you'll see a "no change fees" filter for you to select.
How far is the flight from Tocumen Intl. Airport (PTY) to Madrid Airport?
With around 8 200 kilometres separating Tocumen and Madrid, your flight will be a long one. Pack wisely to make your journey more comfortable. Things like an eye mask and a cosy travel pillow should be in your carry-on bag.
Which airlines fly direct from Panama Airport to Adolfo Suarez Madrid-Barajas Airport (MAD)?
Many savvy travellers like to fly with Iberia (IB) from Tocumen Intl. Airport (PTY) to MAD. This popular airline offers 21 flights every month, so you can pick a flight time that's right for you. Another carrier operating on this route is Air Europa (UX). You'll have 17 flights each month to select from.
Are Panama Airport to Madrid–Barajas Airport flight tickets cheaper when they're purchased at the last minute?
Flight prices change all the time, so it's no sure thing. While last-minute flight deals between Panama Airport and Madrid Airport are possible, it also makes sense to keep an eye on prices well before you fly. In fact, some airlines publish their prices up to a year prior to the departure date. Expedia is constantly updating the biggest bargains around, so keep checking and be ready to lock in your seat when the price is right.

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