Cheap Flights from Mexico City (MEX) to Johannesburg (JNB)

View AU$921 flight on Mon, 25 May 2026Opens in a new window

Popular airlines from Benito Juarez International Airport (MEX) to O.R. Tambo Intl. Airport (JNB)

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Cheap Flights from Mexico City (MEX) to Johannesburg (JNB)

Prices were available within the past 7 days for one-way flights and round trip tickets for the period specified. Prices and availability are subject to change. Additional terms apply.

Air France
Sun, 20 Dec - Sun, 3 Jan
MEX
Mexico City
JNB
Johannesburg
AU$3,542 Return, found 9 hours ago
AU$3,542
Return
found 9 hours ago
Select Air France flight, departing Sun, 20 Dec from Mexico City to Johannesburg, returning Sun, 3 Jan, priced at AU$3,542 found 9 hours ago
LATAM Airlines Group
Sun, 20 Dec - Sun, 3 Jan
MEX
Mexico City
JNB
Johannesburg
AU$3,650 Return, found 9 hours ago
AU$3,650
Return
found 9 hours ago
Select LATAM Airlines Group flight, departing Sun, 20 Dec from Mexico City to Johannesburg, returning Sun, 3 Jan, priced at AU$3,650 found 9 hours ago
Air France
Sun, 20 Dec - Sun, 3 Jan
MEX
Mexico City
JNB
Johannesburg
AU$3,741 Return, found 9 hours ago
AU$3,741
Return
found 9 hours ago
Select Air France flight, departing Sun, 20 Dec from Mexico City to Johannesburg, returning Sun, 3 Jan, priced at AU$3,741 found 9 hours ago
Air France
Sun, 20 Dec - Sun, 3 Jan
MEX
Mexico City
JNB
Johannesburg
AU$3,762 Return, found 9 hours ago
AU$3,762
Return
found 9 hours ago
Select Air France flight, departing Sun, 20 Dec from Mexico City to Johannesburg, returning Sun, 3 Jan, priced at AU$3,762 found 9 hours ago
LATAM Airlines Group
Sun, 20 Dec - Sun, 3 Jan
MEX
Mexico City
JNB
Johannesburg
AU$3,879 Return, found 9 hours ago
AU$3,879
Return
found 9 hours ago
Select LATAM Airlines Group flight, departing Sun, 20 Dec from Mexico City to Johannesburg, returning Sun, 3 Jan, priced at AU$3,879 found 9 hours ago
Air France
Sun, 20 Dec - Sun, 3 Jan
MEX
Mexico City
JNB
Johannesburg
AU$4,012 Return, found 9 hours ago
AU$4,012
Return
found 9 hours ago
Select Air France flight, departing Sun, 20 Dec from Mexico City to Johannesburg, returning Sun, 3 Jan, priced at AU$4,012 found 9 hours ago
Air France
Sun, 20 Dec - Sun, 3 Jan
MEX
Mexico City
JNB
Johannesburg
AU$4,012 Return, found 9 hours ago
AU$4,012
Return
found 9 hours ago
Select Air France flight, departing Sun, 20 Dec from Mexico City to Johannesburg, returning Sun, 3 Jan, priced at AU$4,012 found 9 hours ago
avianca
Sun, 20 Dec - Sun, 3 Jan
MEX
Mexico City
JNB
Johannesburg
AU$4,025 Return, found 9 hours ago
AU$4,025
Return
found 9 hours ago
Select avianca flight, departing Sun, 20 Dec from Mexico City to Johannesburg, returning Sun, 3 Jan, priced at AU$4,025 found 9 hours ago
Delta
Sun, 20 Dec - Sun, 3 Jan
MEX
Mexico City
JNB
Johannesburg
AU$4,039 Return, found 9 hours ago
AU$4,039
Return
found 9 hours ago
Select Delta flight, departing Sun, 20 Dec from Mexico City to Johannesburg, returning Sun, 3 Jan, priced at AU$4,039 found 9 hours ago
United
Sun, 20 Dec - Sun, 3 Jan
MEX
Mexico City
JNB
Johannesburg
AU$4,332 Return, found 9 hours ago
AU$4,332
Return
found 9 hours ago
Select United flight, departing Sun, 20 Dec from Mexico City to Johannesburg, returning Sun, 3 Jan, priced at AU$4,332 found 9 hours ago

Frequently asked questions

How do I find cheap flights from Mexico City (MEX-Mexico City Intl.) to Johannesburg (JNB-O.R. Tambo Intl.)?
To find a cheap flight from Mexico City (MEX-Mexico City Intl.) to Johannesburg (JNB-O.R. Tambo Intl.), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from Mexico City (MEX-Mexico City Intl.) to Johannesburg (JNB-O.R. Tambo Intl.)?
The best time to fly is usually mid-week (Tuesday or Wednesday) and during early morning hours as flights tend to be cheaper, less crowded, and generally more on-time. Avoid major holidays and peak vacation seasons for smoother travel. Combining off-peak days and hours often gives the best combination of cost, comfort, and convenience.
How many flights per day from Mexico City (MEX-Mexico City Intl.) to Johannesburg (JNB-O.R. Tambo Intl.)?
There are approximately 42 connecting flights per day from Mexico City (MEX-Mexico City Intl.) to Johannesburg (JNB-O.R. Tambo Intl.). Some common connection points include Hartsfield-Jackson Atlanta Intl. (ATL), George Bush Intercontinental (IAH), and Adolfo Suarez Madrid-Barajas (MAD).
What is the earliest flight from Mexico City (MEX-Mexico City Intl.) to Johannesburg (JNB-O.R. Tambo Intl.)?
The earliest flight from Mexico City (MEX-Mexico City Intl.) (MEX) to Johannesburg (JNB-O.R. Tambo Intl.) (JNB) typically departs at approximately 12:05 AM local time, operated by Iberia and British Airways. This is a seasonal service active in January and February. An early departure like this can help maximize your time at your destination. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What day of the week has the most flights from Mexico City (MEX-Mexico City Intl.) to Johannesburg (JNB-O.R. Tambo Intl.)?
If you're flying from Mexico City (MEX-Mexico City Intl.) to Johannesburg (JNB-O.R. Tambo Intl.), you'll typically find the most flights on a Thursday, with around 83 flights available. This gives you notably more flight options compared to other days of the week. Major airlines on this route include Aeromexico, United Airlines, and American Airlines.
What are the most popular departure times for flights from Mexico City (MEX-Mexico City Intl.) to Johannesburg (JNB-O.R. Tambo Intl.)?
The most popular departure times for flights from Mexico City (MEX-Mexico City Intl.) to Johannesburg (JNB-O.R. Tambo Intl.) are between 12pm and 3pm. This accounts for around 38% of total traffic. Many major carriers, including United Airlines, Delta Air Lines and American Airlines, offer flights during this window. This timing works well because it allows you to depart around midday, giving you time in the morning before your flight and typically leading to an arrival that's convenient for checking into your accommodation.
How long does it take to fly from Mexico City (MEX-Mexico City Intl.) to Johannesburg (JNB-O.R. Tambo Intl.)?
A flight from MEX to JNB with a layover takes around 22 hours 30 minutes, with the route covering approximately 9,071 miles. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from Mexico City (MEX-Mexico City Intl.) to Johannesburg (JNB-O.R. Tambo Intl.)?
Select the "Business class" and "First class" filters when looking for MEX to JNB flights on Expedia. This is the easiest way to compare prices, routes and flight times for your trip.
How do I earn miles on a Mexico City (MEX-Mexico City Intl.) to Johannesburg (JNB-O.R. Tambo Intl.) flight with Expedia?
It's easy to earn miles on a Mexico City (MEX-Mexico City Intl.) to Johannesburg (JNB-O.R. Tambo Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Johannesburg from Mexico City Intl. (MEX)?
If you're planning to travel to Johannesburg from Mexico City Intl. (MEX), you can fly into O.R. Tambo Intl. (JNB) Some flights may connect through major hubs like George Bush Intercontinental (IAH), Frankfurt Intl. (FRA), Barcelona Intl. (BCN) before reaching Johannesburg. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Mexico City (MEX-Mexico City Intl.) to Johannesburg (JNB-O.R. Tambo Intl.) at the last minute?
Typically, booking a last minute flight from Mexico City (MEX-Mexico City Intl.) to Johannesburg (JNB-O.R. Tambo Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Mexico City (MEX-Mexico City Intl.) to Johannesburg (JNB-O.R. Tambo Intl.) flight and hotel package?
Securing a Mexico City (MEX-Mexico City Intl.) to Johannesburg (JNB-O.R. Tambo Intl.) flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Mexico City (MEX-Mexico City Intl.) to Johannesburg (JNB-O.R. Tambo Intl.)?
If you booked your Mexico City (MEX-Mexico City Intl.) to Johannesburg (JNB-O.R. Tambo Intl.) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Mexico City Intl.
Destination airport
O.R. Tambo Intl.
Airlines serving
Air France, American Airlines, British Airways, Delta, Emirates, LATAM Airlines Group, Lufthansa
Return price
AU$3,542
Distance
14512 km

Book with confidence

Your quick guide to flights from Mexico City to Johannesburg

Pick up great flights from Mexico City to Johannesburg

With Expedia, you have your pick of flights a day with 20 airlines covering flights from Mexico City to Johannesburg. Whether you’re on a business trip, a family holiday or a luxury break, just enter your travel dates, hit search then check out your choice of flights. Select from return, one way or multi-city flights, and use the advance search tool if you want a direct or refundable flight. You can narrow your search to show you just your preferred cabin class and airline, too. It’s all easy. You can book direct flights from Mexico City to Johannesburg that take around hours.

Find cheap flights from Mexico City to Johannesburg

From the great flight deals with prices currently ranging from AU$3,542 to AU$4,332, you can choose to see the cheapest flights first. Generally, you can book the cheapest flights from Mexico City to Johannesburg around 4 to 6 weeks in advance. If your travel dates are flexible, try to avoid weekends and peak seasons – when you are more likely to grab the lowest prices. Even last minute, there are some impressive deals. The cheapest time to fly to Johannesburg is normally in December.

Reasons to book your flight from Mexico City to Johannesburg with Expedia

Expedia makes it easy to find, book, and travel, with everything you need all in one place. When you enter your travel details, find fantastic deals just for you on flight tickets from Mexico City to Johannesburg across all the main airline carriers, so you can save time, dollars, and hassle finding the perfect flight. If you think your plans could change, choose refundable flights so any changes won’t cost you more. Book your flight to Johannesburg right now and, if you join Expedia Rewards, you earn points this time and every time you travel with Expedia.

Your quick guide to flights from Mexico City to Johannesburg

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