Find the cheapest flights on Expedia from Medellín (MDE) to Arequipa (AQP). Flight ticket prices change frequently based on availability and demand. We send price-drop alerts to make air travel simple and flexible. The lowest one-way fare found on Expedia for this route in the past 7 days starts at AU$449 for travel on 27 November 2026.
Cheap Flights from Medellín to Arequipa (MDE-AQP)
Prices were available within the past 7 days and start at AU$449 for one-way flights and AU$895 for return, for the period specified. Prices and availability are subject to change.
Your quick guide to flights from Medellín to Arequipa
Pick up great flights from Medellín to Arequipa
With Expedia, you have your pick of flights a day with 3 airlines covering flights from Medellín to Arequipa. Whether you’re on a business trip, a family holiday or a luxury break, just enter your travel dates, hit search then check out your choice of flights. Select from return, one way or multi-city flights, and use the advance search tool if you want a direct or refundable flight. You can narrow your search to show you just your preferred cabin class and airline, too. It’s all easy. You can book direct flights from Medellín to Arequipa that take around hours.
Find cheap flights from Medellín to Arequipa
From the great flight deals with prices currently ranging from AU$895 to AU$984, you can choose to see the cheapest flights first. Generally, you can book the cheapest flights from Medellín to Arequipa around 4 to 6 weeks in advance. If your travel dates are flexible, try to avoid weekends and peak seasons – when you are more likely to grab the lowest prices. Even last minute, there are some impressive deals. The cheapest time to fly to Arequipa is normally in November.
Reasons to book your flight from Medellín to Arequipa with Expedia
Expedia makes it easy to find, book, and travel, with everything you need all in one place. When you enter your travel details, find fantastic deals just for you on flight tickets from Medellín to Arequipa across all the main airline carriers, so you can save time, dollars, and hassle finding the perfect flight. If you think your plans could change, choose refundable flights so any changes won’t cost you more. Book your flight to Arequipa right now and, if you join Expedia Rewards, you earn points this time and every time you travel with Expedia.