Cheap flights from Mayagüez

View AU$128 flight on Wed, 1 Oct. 2025Opens in a new window

Popular airlines from Mayagüez

  • American Airlines

    American Airlines

  • JetBlue Airways

    JetBlue Airways

  • United

    United

  • Delta

    Delta

  • Frontier Airlines

    Frontier Airlines

  • Spirit Airlines

    Spirit Airlines

  • Southwest Airlines

    Southwest Airlines

  • Plan, book, fly with confidence

  • trending down icon

    Be in the know

    Get alerts if flight prices drop or rise*
  • bex rewards loyalty icon

    Book smarter

    Save up to 35% on select hotels after you book a flight*
  • payments icon

    Earn twice

    Earn your airline miles on top of our rewards
    Sign in

Cheapest flights from Mayagüez

These prices were available within the past 7 days. Prices quoted are per person, return, for the period specified. Prices and availability are subject to change. Additional terms apply.

Arajet
Sun, 30 Nov. - Sun, 7 Dec.
SJU
San Juan
SDQ
Santo Domingo
AU$304 Return, found 2 days ago
AU$304
Return
found 2 days ago
Select Arajet flight, departing Sun, 30 Nov. from San Juan to Santo Domingo, returning Sun, 7 Dec., priced at AU$304 found 2 days ago
Arajet
Sun, 30 Nov. - Sun, 7 Dec.
SJU
San Juan
SDQ
Santo Domingo
AU$311 Return, found 2 days ago
AU$311
Return
found 2 days ago
Select Arajet flight, departing Sun, 30 Nov. from San Juan to Santo Domingo, returning Sun, 7 Dec., priced at AU$311 found 2 days ago
Delta
Sat, 20 Sep. - Sat, 27 Sep.
SJU
San Juan
JFK
New York
AU$324 Return, found 3 days ago
AU$324
Return
found 3 days ago
Select Delta flight, departing Sat, 20 Sep. from San Juan to New York, returning Sat, 27 Sep., priced at AU$324 found 3 days ago
Copa
Thu, 6 Nov. - Mon, 10 Nov.
SJU
San Juan
SDQ
Santo Domingo
AU$364 Return, found 2 days ago
AU$364
Return
found 2 days ago
Select Copa flight, departing Thu, 6 Nov. from San Juan to Santo Domingo, returning Mon, 10 Nov., priced at AU$364 found 2 days ago
World Ticket Ltd
Sun, 30 Nov. - Sun, 7 Dec.
SJU
San Juan
SDQ
Santo Domingo
AU$368 Return, found 2 days ago
AU$368
Return
found 2 days ago
Select World Ticket Ltd flight, departing Sun, 30 Nov. from San Juan to Santo Domingo, returning Sun, 7 Dec., priced at AU$368 found 2 days ago
Copa
Thu, 6 Nov. - Mon, 10 Nov.
SJU
San Juan
SDQ
Santo Domingo
AU$380 Return, found 2 days ago
AU$380
Return
found 2 days ago
Select Copa flight, departing Thu, 6 Nov. from San Juan to Santo Domingo, returning Mon, 10 Nov., priced at AU$380 found 2 days ago
Delta
Sat, 20 Sep. - Sat, 27 Sep.
SJU
San Juan
JFK
New York
AU$417 Return, found 3 days ago
AU$417
Return
found 3 days ago
Select Delta flight, departing Sat, 20 Sep. from San Juan to New York, returning Sat, 27 Sep., priced at AU$417 found 3 days ago
World Ticket Ltd
Sun, 30 Nov. - Sun, 7 Dec.
SJU
San Juan
SDQ
Santo Domingo
AU$419 Return, found 2 days ago
AU$419
Return
found 2 days ago
Select World Ticket Ltd flight, departing Sun, 30 Nov. from San Juan to Santo Domingo, returning Sun, 7 Dec., priced at AU$419 found 2 days ago
Delta
Fri, 19 Sep. - Sun, 21 Sep.
SJU
San Juan
JFK
New York
AU$420 Return, found 3 days ago
AU$420
Return
found 3 days ago
Select Delta flight, departing Fri, 19 Sep. from San Juan to New York, returning Sun, 21 Sep., priced at AU$420 found 3 days ago
United
Sat, 20 Sep. - Sat, 27 Sep.
SJU
San Juan
EWR
New York
AU$442 Return, found 3 days ago
AU$442
Return
found 3 days ago
Select United flight, departing Sat, 20 Sep. from San Juan to New York, returning Sat, 27 Sep., priced at AU$442 found 3 days ago

Flights from Mayagüez: Essential Travel Information

Cheapest flight from Mayagüez
AU$304 (roundtrip)
Best airlines to fly from Mayagüez
Arajet, Delta, American Airlines, World Ticket Ltd, Copa, United
Cheapest month to fly from Mayagüez
November
Mayagüez IATA code
SJU
Mayagüez Country/State
Puerto Rico
Airline ticket deals from Mayagüez
AU$304 - AU$442
*Available to Expedia members.