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Our top choices for Wapello hotels

Best Western Mt. Pleasant Inn

Best Western Mt. Pleasant Inn
2.5 star property
Mount Pleasant
8.2 out of 10, Very good, (798 reviews)
"Very friendly staff hotel is older could use some upgrades"
United States
Angela
The price is AU$91
includes taxes & fees
9 Mar - 10 Mar
Best Western Mt. Pleasant Inn

Idyllic Biggsville Vacation Rental: 10 Mi to River

Idyllic Biggsville Vacation Rental: 10 Mi to River
3.0 star property
Biggsville
10.0 out of 10, Exceptional, (3 reviews)
"Outstanding value and extremely nice place, you won't be disappointed. "
United States
Joe
The price is AU$285
includes taxes & fees
12 Mar - 13 Mar
Idyllic Biggsville Vacation Rental: 10 Mi to River

AmericInn by Wyndham Muscatine

AmericInn by Wyndham Muscatine
2.5 star property
Muscatine
7.6 out of 10, Good, (432 reviews)
"Rooms clean. Staff amazing!"
United States
ASHLEY
The price is AU$133
includes taxes & fees
19 Mar - 20 Mar
AmericInn by Wyndham Muscatine

The Sage Hotel

The Sage Hotel
2.0 star property
Muscatine
7.0 out of 10, Good, (63 reviews)
"Awesome "
United States
Dauda
The Sage Hotel

Evans Holly Grove Inn B&B

Evans Holly Grove Inn B&B
4.0 star property
Burlington
9.6 out of 10, Exceptional, (203 reviews)
"Beautifully furnished historic house that has been well cared for. Grandma Mel was a delight. "
United States
Teresa
The price is AU$152
includes taxes & fees
12 Mar - 13 Mar
Evans Holly Grove Inn B&B

Super 8 by Wyndham Mt Pleasant

Super 8 by Wyndham Mt Pleasant
2.0 star property
Mount Pleasant
8.2 out of 10, Very good, (845 reviews)
"Great place"
United States
peter
The price is AU$98
includes taxes & fees
5 Mar - 6 Mar
Super 8 by Wyndham Mt Pleasant

Comfort Inn Muscatine near Hwy 61

Comfort Inn Muscatine near Hwy 61
2.5 star property
Muscatine
7.8 out of 10, Good, (225 reviews)
"great room, best breakfast each morning. Made my vacation very enjoyable."
United States
RICHARD
The price is AU$110
includes taxes & fees
29 Mar - 30 Mar
Comfort Inn Muscatine near Hwy 61

Quality Inn & Suites Mount Pleasant

Quality Inn & Suites Mount Pleasant
2.5 star property
Mount Pleasant
8.0 out of 10, Very good, (125 reviews)
"Check in was easy and fast. Room was clean and quiet. "
United States
William
The price is AU$89
includes taxes & fees
22 Mar - 23 Mar
Quality Inn & Suites Mount Pleasant

Hall Building

Hall Building
2.0 star property
Aledo
10.0 out of 10, Exceptional, (1 review)
The price is AU$412
includes taxes & fees
5 Mar - 6 Mar
Hall Building

The Catfish Bend Inn & Spa

The Catfish Bend Inn & Spa
3.5 star property
Burlington
9.2 out of 10, Wonderful, (345 reviews)
"The room and the staff were both amazing "
United States
Tina
The price is AU$243
includes taxes & fees
12 Mar - 13 Mar
The Catfish Bend Inn & Spa

Best Western Muscatine / Pearl City Hotel

Best Western Muscatine / Pearl City Hotel
2.5 star property
Muscatine
8.6 out of 10, Excellent, (508 reviews)
"Staff was very friendly and helpful. Free soup at night was very good and warming when temps got below 10. Nice touch."
United States
Andrew
The price is AU$139
includes taxes & fees
8 Mar - 9 Mar
Best Western Muscatine / Pearl City Hotel

Hampton Inn Muscatine

Hampton Inn Muscatine
2.5 star property
Muscatine
8.4 out of 10, Very good, (471 reviews)
"Nice stay"
United States
Bradlee Dean
The price is AU$149
includes taxes & fees
15 Mar - 16 Mar
Hampton Inn Muscatine

AmericInn by Wyndham West Burlington

AmericInn by Wyndham West Burlington
2.5 star property
West Burlington
7.0 out of 10, Good, (854 reviews)
"Friendly staff, clean room, comfortable bed, complimentary breakfast. Online pre- check-in & free parking. Like that this location is just off the highway/interstate. "
United States
Kipp
The price is AU$115
includes taxes & fees
25 Mar - 26 Mar
AmericInn by Wyndham West Burlington

Fairfield Inn & Suites by Marriott Burlington

Fairfield Inn & Suites by Marriott Burlington
3.0 star property
Burlington
8.4 out of 10, Very good, (302 reviews)
"It was quiet & they gave us water, when we checked in, was hot out, so that was so nice!"
United States
Loren
The price is AU$198
includes taxes & fees
3 Apr - 4 Apr
Fairfield Inn & Suites by Marriott Burlington

Holiday Inn Express Hotel & Suites Burlington by IHG

Holiday Inn Express Hotel & Suites Burlington by IHG
2.5 star property
Burlington
8.6 out of 10, Excellent, (478 reviews)
"Clean room, very comfortable beds"
United States
Julie Or Hank
The price is AU$224
includes taxes & fees
8 Mar - 9 Mar
Holiday Inn Express Hotel & Suites Burlington by IHG

Super 8 by Wyndham Muscatine

Super 8 by Wyndham Muscatine
2.0 star property
Muscatine
6.4 out of 10, (281 reviews)
"Staff was nice, let me check in a little early, quiet, comfortable bed."
United States
Mark
The price is AU$101
includes taxes & fees
11 Mar - 12 Mar
Super 8 by Wyndham Muscatine

Hampton Inn & Suites Burlington

Hampton Inn & Suites Burlington
2.5 star property
Burlington
9.6 out of 10, Exceptional, (322 reviews)
"Clean room, nice staff "
United States
Michael
The price is AU$221
includes taxes & fees
15 Mar - 16 Mar
Hampton Inn & Suites Burlington

Quality Inn Burlington near Hwy 34

Quality Inn Burlington near Hwy 34
2.5 star property
Burlington
7.4 out of 10, Good, (404 reviews)
"well cared for inexpensive property "
United States
Christopher
The price is AU$120
includes taxes & fees
2 Apr - 3 Apr
Quality Inn Burlington near Hwy 34

The Merrill Hotel, Muscatine, a Tribute Portfolio Hotel

The Merrill Hotel, Muscatine, a Tribute Portfolio Hotel
4.0 star property
Muscatine
9.6 out of 10, Exceptional, (283 reviews)
"clean facility, very friendly and helpful staff"
United States
Larry
The price is AU$308
includes taxes & fees
20 Mar - 21 Mar
The Merrill Hotel, Muscatine, a Tribute Portfolio Hotel

Fun City Resort Hotel

Fun City Resort Hotel
3.5 star property
Burlington
8.4 out of 10, Very good, (308 reviews)
"Room was great — Every staff member we came in contact with was extremely courteous & helpful."
United States
Susan
Fun City Resort Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Learn more about Wapello

Along the banks of the mighty Mississippi, this charming river town invites visitors to explore Chatauqua Park's natural beauty and peaceful surroundings. History buffs and outdoor enthusiasts can venture to nearby Lover's Leap Swinging Bridge or spend an exciting evening watching local races at CJ Speedway.

The Mississippi River near Hannibal, Missouri, USA

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Frequently asked questions

Where is the best place for a stay in Wapello?
Located 24.9 mi (40.1 km) from the heart of Wapello, The Catfish Bend Inn & Spa is a top choice for your stay, based on our traveller data. Two other choices for your stay in the area are Best Western Muscatine / Pearl City Hotel and Fun City Resort Hotel. See all available top hotels, or vacation rentals in Wapello.
What are some of the best holiday rentals that Wapello has to offer?
Large cozy cottage rental: This holiday home rental outside of Wapello is located in a rural location, and has a patio, a selection of games and a BBQ to put you at ease in your new surroundings. It has 4 bedrooms, as well as a kitchen with a dishwasher, a fridge and a stovetop, so that you can cook with friends or family. See all vacation rentals in Wapello.
If I need to cancel my hotel reservation in Wapello, will I receive a refund?
Yes, you'll find most hotel bookings are fully refundable if cancelled prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you have a reservation that's non-refundable, you might be able to cancel it and get a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in Wapello.
What is staying in Wapello like?
Visitors will definitely enjoy all that Wapello has to offer. There are 64 hotels and other accommodation options in the surrounding area. Find out more about Wapello.
What should I see while I'm in Wapello?
A favourite place to visit is Mississippi River. You'll also find Cairo Woods Wildlife Area and CJ Speedway in the area. Take a look at what more there is to see and do in Expedia's Wapello guide.
What's the weather like in Wapello?
The hottest months are usually July and August, with an average temperature of 22°C, while the coldest months are January and February, with an average of -1°C. The snowiest months in Wapello are January, November, February and December, with each month seeing an average of 18 cm of snowfall.

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