Business Hotels & Resorts in Southwestern Virginia from AU$113

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Check availability on Southwestern Virginia Business Hotels

Tonight
6 Dec - 7 Dec
Tomorrow
7 Dec - 8 Dec
Next weekend
12 Dec - 14 Dec
In two weeks
19 Dec - 21 Dec

Best Southwestern Virginia Business Hotels

Front of property – evening/night
The Bolling Wilson Hotel

The Bolling Wilson Hotel

3.0 star property
Wytheville
9.6 out of 10, Exceptional, (773)
"Great place. Great staff"
United States
Kevin
The price is AU$229
includes taxes & fees
8 Dec - 9 Dec
The Bolling Wilson Hotel
Lobby
Comfort Inn & Suites Hillsville I-77

Comfort Inn & Suites Hillsville I-77

2.5 star property
Hillsville
9.2 out of 10, Wonderful, (1002)
"Great price, friendly staff and clean room!"
United States
Pearl
The price is AU$147
includes taxes & fees
4 Jan - 5 Jan 2026
Comfort Inn & Suites Hillsville I-77
Exterior
La Quinta Inn & Suites by Wyndham Roanoke Salem

La Quinta Inn & Suites by Wyndham Roanoke Salem

3.0 star property
Salem
9.0 out of 10, Wonderful, (1331)
"Great place to stay"
United States
Bruce
The price is AU$161
includes taxes & fees
8 Dec - 9 Dec
La Quinta Inn & Suites by Wyndham Roanoke Salem
Front of property
General Francis Marion Hotel

General Francis Marion Hotel

4.0 star property
Marion
9.4 out of 10, Exceptional, (993)
"Great clean and safe place to stay! "
United States
Grant
The price is AU$184
includes taxes & fees
8 Dec - 9 Dec
General Francis Marion Hotel
Room, 2 Queen Beds
Spark by Hilton Roanoke Civic Center

Spark by Hilton Roanoke Civic Center

2.5 star property
Gainsboro
9.0 out of 10, Wonderful, (126)
"The rooms were very clean and the staff was very nice! The breakfast is always a plus!"
United States
Katelyn
The price is AU$128
includes taxes & fees
12 Dec - 13 Dec
Spark by Hilton Roanoke Civic Center
Interior entrance
Travelodge by Wyndham Wytheville

Travelodge by Wyndham Wytheville

2.0 star property
Wytheville
8.2 out of 10, Very good, (1272)
"Room was clean and the front desk clerk was very helpful,"
United States
Rosemary
The price is AU$113
includes taxes & fees
8 Dec - 9 Dec
Travelodge by Wyndham Wytheville
Deluxe Room
Hotel Floyd

Hotel Floyd

2.0 star property
Floyd
9.6 out of 10, Exceptional, (493)
"Clean room, friendly staff, lovely artwork, short walk to restaurants. "
United States
Kathryn
The price is AU$183
includes taxes & fees
1 Jan - 2 Jan 2026
Hotel Floyd
Lounge
Jackson Park Inn, an Ascend Collection Hotel

Jackson Park Inn, an Ascend Collection Hotel

2.5 star property
Pulaski
9.4 out of 10, Exceptional, (712)
"Very clean. Beautiful rooms. Overall a great place to stay!"
United States
Martin
The price is AU$159
includes taxes & fees
4 Jan - 5 Jan 2026
Jackson Park Inn, an Ascend Collection Hotel
Exterior
Country Inn & Suites by Radisson, Abingdon, VA

Country Inn & Suites by Radisson, Abingdon, VA

2.5 star property
Abingdon
9.2 out of 10, Wonderful, (1178)
"The staff were all so nice, the room was clean, breakfast was really good."
United States
Tina
The price is AU$171
includes taxes & fees
26 Dec - 27 Dec
Country Inn & Suites by Radisson, Abingdon, VA
Suite, Non Smoking
Comfort Suites Abingdon I-81

Comfort Suites Abingdon I-81

2.5 star property
Abingdon
9.2 out of 10, Wonderful, (1001)
"Was a great place to stay. "
United States
Dan
The price is AU$160
includes taxes & fees
3 Jan - 4 Jan 2026
Comfort Suites Abingdon I-81
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Southwestern Virginia Hotel Reviews

Sleep Inn Wytheville I-77 and I-81

Sleep Inn Wytheville I-77 and I-81

10/10 Excellent
"It is a great 1/2 way point to Myrtle Beach for us. Great price, clean, very helpful friendly staff. We have nothing but good things to say about the Sleep Inn in Wytheville. Would definately stay again."
Martha 1-night trip
Posted 1 day ago
Sleep Inn Wytheville I-77 and I-81

Frequently asked questions

How much do business-friendly hotels in Southwestern Virginia cost?
Prices for business hotels in Southwestern Virginia range between AU$113 and AU$229 per night. Whatever your budget, Expedia will help you find the ideal place to complete the job. This price was available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
How many business-friendly hotels are there in Southwestern Virginia?
When you need to travel for work in Southwestern Virginia, there are 145 business-friendly hotels to choose from.
What is there to do in Southwestern Virginia near my business-friendly hotel?
Whatever you're interested in, there are plenty of ways to fill your downtime in Southwestern Virginia. If you're visiting Roanoke, be sure to look around Virginia Museum of Transportation, Taubman Museum of Art and Mill Mountain Zoo. Taking off to Blacksburg? Lyric Theatre, Museum of Geosciences and Virginia Tech University are among the top attractions in this city.

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