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Business Hotels & Resorts in Southwest Oklahoma from AU$110

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Best Southwest Oklahoma Business Hotels

AmericInn by Wyndham Sayre

2.5 star property
Sayre
8.6 out of 10, Excellent, (545)
"Excellent location, super clean, friendly staff. "
United States
Pedro
The price is AU$148
includes taxes & fees
3 Jan - 4 Jan 2026
AmericInn by Wyndham Sayre

La Quinta Inn & Suites by Wyndham Clinton Historic Route 66

3.0 star property
Clinton
9.2 out of 10, Wonderful, (1000)
"I've stayed here several times and would recommend it for the area."
United States
joey
The price is AU$150
includes taxes & fees
31 Dec - 1 Jan 2026
La Quinta Inn & Suites by Wyndham Clinton Historic Route 66

Lucille's Hotel, Restaurant, & Bar

2.5 star property
Weatherford
9.0 out of 10, Wonderful, (468)
"Good staff. The food was good. A great place to stay. I've traveled up and down I-40 for 10 years and it's the best place I found to stay. Will definitely stay again"
United States
James
The price is AU$154
includes taxes & fees
13 Dec - 14 Dec
Lucille's Hotel, Restaurant, & Bar

Home2 Suites by Hilton Weatherford

3.0 star property
Weatherford
9.4 out of 10, Exceptional, (277)
"Good location with many dining and shopping options nearby."
United States
Ann
The price is AU$125
includes taxes & fees
14 Dec - 15 Dec
Home2 Suites by Hilton Weatherford

Best Western Plus Executive Residency Elk City

3.0 star property
Elk City
8.6 out of 10, Excellent, (775)
"Room was ok, staff were nice, good breakfast "
United States
Tim
The price is AU$131
includes taxes & fees
2 Jan - 3 Jan 2026
Best Western Plus Executive Residency Elk City

Sleep Inn & Suites

2.5 star property
Elk City
8.2 out of 10, Very good, (1000)
"Clean and comfortable at a good price. "
United States
Dean
The price is AU$110
includes taxes & fees
3 Jan - 4 Jan 2026
Sleep Inn & Suites

Apache Casino Hotel

3.5 star property
Lawton
9.0 out of 10, Wonderful, (1005)
"Nice room good stay"
United States
Bryce
The price is AU$141
includes taxes & fees
7 Dec - 8 Dec
Apache Casino Hotel

Holiday Inn Express Hotel & Suites Elk City by IHG

2.5 star property
Elk City
9.2 out of 10, Wonderful, (637)
"Clean room, decent breakfast "
United States
Virginia
The price is AU$146
includes taxes & fees
20 Dec - 21 Dec
Holiday Inn Express Hotel & Suites Elk City by IHG

Best Western Plus Weatherford

2.5 star property
Weatherford
9.0 out of 10, Wonderful, (1000)
"Not as good as last time we stayed here, seemed to be short staffed. Breakfast a huge disappointment. Bed good. Housekeeping fair. Not sure we’ll stay again"
United States
George
The price is AU$153
includes taxes & fees
20 Dec - 21 Dec
Best Western Plus Weatherford

Fairfield Inn & Suites by Marriott Weatherford

2.5 star property
Weatherford
9.0 out of 10, Wonderful, (692)
"Clean, quiet, & comfy, a pleasant staff and a great breakfast!"
United States
Stephen
The price is AU$178
includes taxes & fees
4 Jan - 5 Jan 2026
Fairfield Inn & Suites by Marriott Weatherford
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Southwest Oklahoma Hotel Reviews

Frequently asked questions

How much do business-friendly hotels in Southwest Oklahoma cost?
Rates for business hotels in Southwest Oklahoma range between AU$110 and AU$178 per night. No matter your budget, Expedia can help you locate the ideal space for a smooth work trip. This price was available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
How many business-friendly hotels are there in Southwest Oklahoma?
When work takes you on the road in Southwest Oklahoma, you'll have 60 business-friendly hotels to choose from.
What is there to do in Southwest Oklahoma near my business-friendly hotel?
No matter your interests, there are many things to keep you entertained in Southwest Oklahoma. If you're making your way to Lawton, be sure to look around Comanche National Museum and Cultural Centre, Comanche Nation Waterpark and Museum of the Great Plains. Planning to stay in Clinton? Water-Zoo Indoor Water Park, Yippee Ay-O-K Winery and Lucky Starr Casino are among the top sights here.

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