Siesta Isle Hotels, Fort Myers Beach

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Next weekend
In two weeks

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Siesta Isle hotels

Latitude 26 Waterfront Boutique Resort - Fort Myers Beach

Latitude 26 Waterfront Boutique Resort - Fort Myers Beach
2.5 star property
Siesta Isle
8.8 out of 10, Excellent, (1,004 reviews)
"Amazing place to stay! "
United States
Kristen
The price is AU$180
includes taxes & fees
4 May - 5 May
Latitude 26 Waterfront Boutique Resort - Fort Myers Beach

Lani Kai Beachfront Resort

Lani Kai Beachfront Resort
3.5 star property
2.7 km from Siesta Isle
9.0 out of 10, Wonderful, (1,449 reviews)
"Loved the resort and amenities"
United States
Steven
The price is AU$257
includes taxes & fees
6 May - 7 May
Lani Kai Beachfront Resort

The Bay Inn at Lani Kai

The Bay Inn at Lani Kai
3.0 star property
2.7 km from Siesta Isle
7.6 out of 10, Good, (398 reviews)
"Excellent. We just enjoy so much !!Rooms very clean and just across de beach !!"
United States
Marie
The price is AU$211
includes taxes & fees
4 May - 5 May
The Bay Inn at Lani Kai

The Anchor Inn

The Anchor Inn
2.0 star property
9.7 km from Siesta Isle
10.0 out of 10, Exceptional, (31 reviews)
"Anchor Inn is not only in a great location but beautiful. We used the bikes every day!"
United States
Renee
The price is AU$324
includes taxes & fees
14 May - 15 May
The Anchor Inn

The Perry Hotel Naples

The Perry Hotel Naples
4.5 star property
26.4 km from Siesta Isle
9.4 out of 10, Exceptional, (782 reviews)
"Great stay, beautiful room and great amenities "
United States
Monica
The price is AU$324
includes taxes & fees
2 June - 3 June
The Perry Hotel Naples

Pointe Estero Beach Resort

Pointe Estero Beach Resort
2.0 star property
South Island, 8.2 km from Siesta Isle
9.2 out of 10, Wonderful, (1,001 reviews)
"Love this place!!"
United States
Teneille
The price is AU$662
includes taxes & fees
6 May - 7 May
Pointe Estero Beach Resort

Sanibel Island Beach Resort

Sanibel Island Beach Resort
3.0 star property
10.1 km from Siesta Isle
9.2 out of 10, Wonderful, (1,847 reviews)
"Great restaurant and beach bar on premises. "
United States
Bruce
The price is AU$396
includes taxes & fees
2 June - 3 June
Sanibel Island Beach Resort

Comfort Suites Fort Myers East I-75

Comfort Suites Fort Myers East I-75
2.5 star property
25.5 km from Siesta Isle
9.6 out of 10, Exceptional, (452 reviews)
"Loved my stay here, will be back soon and will book my room here. Breakfast options were nice and staff were very friendly! "
United States
Richard
The price is AU$137
includes taxes & fees
31 May - 1 June
Comfort Suites Fort Myers East I-75

Shangri-La Springs

Shangri-La Springs
2.5 star property
23.4 km from Siesta Isle
9.2 out of 10, Wonderful, (213 reviews)
"Loved our room, updated and clean. Very comfy bed, pillows and linens. Too bad the pool was closed. Would definitely stay again."
United States
Michelle
The price is AU$194
includes taxes & fees
3 May - 4 May
Shangri-La Springs

Fairways Inn of Naples

Fairways Inn of Naples
3.0 star property
28.6 km from Siesta Isle
9.4 out of 10, Exceptional, (1,290 reviews)
"Highly recommend staying here, everything was great."
United States
Jill S
The price is AU$123
includes taxes & fees
27 May - 28 May
Fairways Inn of Naples

Pink Shell Beach Resort and Marina

Pink Shell Beach Resort and Marina
4.0 star property
1.8 km from Siesta Isle
9.4 out of 10, Exceptional, (1,337 reviews)
"Wonderful stay overall. Breakfast buffet was tasty, staff was always attentive, abundant wait staff, beautiful views, adults only pool, and although a resort, didn’t feel penned in."
United States
William Mark
The price is AU$421
includes taxes & fees
6 May - 7 May
Pink Shell Beach Resort and Marina

Holiday Inn Express & Suites Fort Myers Airport by IHG

Holiday Inn Express & Suites Fort Myers Airport by IHG
2.5 star property
17.9 km from Siesta Isle
9.6 out of 10, Exceptional, (1,007 reviews)
"Excellent location, friendly staff and great price."
United States
Leonel
The price is AU$153
includes taxes & fees
9 May - 10 May
Holiday Inn Express & Suites Fort Myers Airport by IHG

Latitude 26 Waterfront Resort & Marina

Latitude 26 Waterfront Resort & Marina
3.0 star property
1.1 km from Siesta Isle
8.6 out of 10, Excellent, (1,001 reviews)
"Place is quiet and right down the street from the beach"
United States
Bryan
The price is AU$157
includes taxes & fees
3 May - 4 May
Latitude 26 Waterfront Resort & Marina

Latitude 26 Waterfront Boutique Resort - Bonita Springs

Latitude 26 Waterfront Boutique Resort - Bonita Springs
3.0 star property
20.4 km from Siesta Isle
8.8 out of 10, Excellent, (767 reviews)
"Lovely boutique style hotel. Right on the water. Had a great stay."
United States
Jeffrey
The price is AU$182
includes taxes & fees
4 May - 5 May
Latitude 26 Waterfront Boutique Resort - Bonita Springs

La Quinta Inn & Suites by Wyndham Bonita Springs Naples N.

La Quinta Inn & Suites by Wyndham Bonita Springs Naples N.
3.0 star property
22.8 km from Siesta Isle
9.0 out of 10, Wonderful, (1,382 reviews)
"Great place! "
United States
Ben
The price is AU$149
includes taxes & fees
4 May - 5 May
La Quinta Inn & Suites by Wyndham Bonita Springs Naples N.

Extended Stay America Premier Suites - Fort Myers - Airport

Extended Stay America Premier Suites - Fort Myers - Airport
2.5 star property
12.3 km from Siesta Isle
8.8 out of 10, Excellent, (962 reviews)
"Great stay"
United States
Cliff
The price is AU$92
includes taxes & fees
3 May - 4 May
Extended Stay America Premier Suites - Fort Myers - Airport

Comfort Inn Fort Myers Northeast

Comfort Inn Fort Myers Northeast
2.5 star property
28.1 km from Siesta Isle
7.8 out of 10, Good, (723 reviews)
"Excellent, friendly front desk staff - at arrival and departure. Terrific bed pillows and climate control. Then, there was breakfast -- first, no coffee and second, cold scrambled eggs, gummy English muffins and no butter. Waffle House is a walkable alternative"
United States
barbara
The price is AU$117
includes taxes & fees
17 May - 18 May
Comfort Inn Fort Myers Northeast

Days Inn & Suites by Wyndham Bonita Springs North Naples

Days Inn & Suites by Wyndham Bonita Springs North Naples
2.5 star property
25.6 km from Siesta Isle
8.0 out of 10, Very good, (1,004 reviews)
"Good staying in "
United States
Ana Laura
The price is AU$123
includes taxes & fees
4 May - 5 May
Days Inn & Suites by Wyndham Bonita Springs North Naples

TownePlace Suites by Marriott Fort Myers Gulf Coast

TownePlace Suites by Marriott Fort Myers Gulf Coast
3.0 star property
15.9 km from Siesta Isle
9.2 out of 10, Wonderful, (189 reviews)
"Such fantastic staff"
United States
Emily
The price is AU$159
includes taxes & fees
29 May - 30 May
TownePlace Suites by Marriott Fort Myers Gulf Coast

Residence Inn by Marriott Fort Myers Sanibel

Residence Inn by Marriott Fort Myers Sanibel
3.0 star property
2.7 km from Siesta Isle
8.8 out of 10, Excellent, (1,000 reviews)
"Loved having two bedrooms, two bathrooms, and a full sized refrigerator. Breakfast was fantastic! Lots of choices!"
United States
Sheila Margaret
The price is AU$159
includes taxes & fees
4 May - 5 May
Residence Inn by Marriott Fort Myers Sanibel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Our guide on where to stay in Siesta Isle

Find the best Siesta Isle areas for the activities you enjoy most.

Mid Island

While visiting Mid Island, you might make a stop by sights like Castle Beach and Estero Boulevard Beach.

South Island

While visiting South Island, you might make a stop by sights like Castle Beach and Santini Marina Shopping Plaza.

TP Hill's

When in TP Hill's, you can plan a visit to Key West Express and Estero Boulevard Beach, some noteworthy sights in the nearby area.

Downtown Fort Myers Beach

If you're spending some time in Downtown Fort Myers Beach, Lynn Hall Memorial Park and Estero Boulevard Beach are top sights worth seeing.

Laguna Shores

While Laguna Shores may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Lover's Key Beach and Santini Marina Shopping Plaza.

Top Siesta Isle Hotel Reviews

Frequently asked questions

What is Siesta Isle like?
Travellers will be sure to find plenty to entertain them in Fort Myers Beach's Siesta Isle neighbourhood. Consider a visit to San Carlos Bay - Bunche Beach Preserve as part of your Siesta Isle travel plans.
Where is the best place to stay in Siesta Isle?
Based on our traveller data, Latitude 26 Waterfront Boutique Resort - Fort Myers Beach is one of the top choices for your stay in Siesta Isle. This hotel offers a marina and free breakfast.
How many hotels will I find in the Siesta Isle area?
If you're searching for places to stay in Fort Myers Beach, Expedia has something to meet your needs with 24 Siesta Isle hotels and other accommodation options to choose from.
If I need to cancel my hotel reservation in Siesta Isle, will I receive a refund?
Yes! You'll find that most hotel reservations are refundable provided that you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of your check-in date. If you booked a non-refundable reservation, it may still be possible to cancel it and be given a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then use the "fully refundable" filter to view the best deals in Siesta Isle.
What are the top things to see and do in Siesta Isle?
San Carlos Bay - Bunche Beach Preserve is an attraction you might want to check out while you're in Siesta Isle. Bunche Beach and Jungle Golf Ft. Myers are also worth a visit when you're out sightseeing in Fort Myers Beach.