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Our top choices for Sedgewickville hotels

Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau
2.5 star property
Cape Girardeau
9.6 out of 10, Exceptional, (104)
"The most impressive thing was the cleanliness throughout the whole property, not just the spotless rooms."
United States
Cassie
Travelling for leisure
The price is AU$151
includes taxes & fees
4 Jan - 5 Jan 2026
Tru By Hilton Cape Girardeau

EC Reed's Mercantile and Hotel

EC Reed's Mercantile and Hotel
3.0 star property
Marble Hill
9.6 out of 10, Exceptional, (84)
"Great, clean room and the restaurant attached was delicious- best breakfast!"
United States
Christina
Travelling with partner
EC Reed's Mercantile and Hotel

Quality Inn Cape Girardeau North

Quality Inn Cape Girardeau North
2.5 star property
Cape Girardeau
7.2 out of 10, Good, (687)
"The area was safe & convenient to food"
United States
Sheri
Travelling with family
The price is AU$99
includes taxes & fees
8 Jan - 9 Jan 2026
Quality Inn Cape Girardeau North

Town House Inn

Town House Inn
2.5 star property
Jackson
7.6 out of 10, Good, (426)
"This hotel is located in a very good spot in Jackson Missouri is very clean."
United States
NAKEISHIA
Travelling with family
The price is AU$103
includes taxes & fees
28 Jan - 29 Jan 2026
Town House Inn

Comfort Suites Jackson-Cape Girardeau

Comfort Suites Jackson-Cape Girardeau
2.5 star property
Jackson
8.2 out of 10, Very good, (740)
"Room was clean and affordable for one night"
United States
Lori
Travelling solo
The price is AU$129
includes taxes & fees
4 Jan - 5 Jan 2026
Comfort Suites Jackson-Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
3.0 star property
Jackson
9.0 out of 10, Wonderful, (677)
"Staff was friendly comfortable beds. in a nice quiet room"
United States
Nicole
Travelling for leisure
The price is AU$136
includes taxes & fees
7 Jan - 8 Jan 2026
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Madison Inn Lodge

Madison Inn Lodge
2.5 star property
Fredericktown
7.6 out of 10, Good, (297)
"room was clean and comfortable"
United States
Steve
Travelling for leisure
The price is AU$127
includes taxes & fees
1 Jan - 2 Jan 2026
Madison Inn Lodge

Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO
3.0 star property
Jackson
9.6 out of 10, Exceptional, (1003)
"The room was very clean."
United States
Darla
Travelling with family
The price is AU$131
includes taxes & fees
29 Dec - 30 Dec
Drury Inn & Suites Jackson MO

Holiday Inn Express & Suites Perryville by IHG

Holiday Inn Express & Suites Perryville by IHG
2.5 star property
Perryville
9.2 out of 10, Wonderful, (544)
"Yes our room was great very clean we had everything we needed."
United States
Connie
The price is AU$155
includes taxes & fees
1 Jan - 2 Jan 2026
Holiday Inn Express & Suites Perryville by IHG

Urban Lofts

Urban Lofts
3.0 star property
Perryville
9.2 out of 10, Wonderful, (17)
"Great place to stay! "
United States
Eric
Urban Lofts

Super 8 by Wyndham Perryville

Super 8 by Wyndham Perryville
2.0 star property
Perryville
8.4 out of 10, Very good, (943)
"Very clean and rooms might have been renovated last year."
United States
David
The price is AU$113
includes taxes & fees
4 Jan - 5 Jan 2026
Super 8 by Wyndham Perryville

Days Inn by Wyndham Perryville

Days Inn by Wyndham Perryville
2.0 star property
Perryville
6.8 out of 10, (415)
"Was a nice place."
United States
Lesliee
The price is AU$106
includes taxes & fees
30 Dec - 31 Dec
Days Inn by Wyndham Perryville

Quality Inn Perryville I-55

Quality Inn Perryville I-55
2.5 star property
Perryville
6.6 out of 10, (124)
"Nice place would recommend Mary Jane’s if you’re looking for good food "
United States
Andrew
The price is AU$124
includes taxes & fees
29 Dec - 30 Dec
Quality Inn Perryville I-55
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

What's the best place for a stay in Sedgewickville?
Secluded 5-Bedroom Lodge with Private Lake – Perfect for Large Groups!, located 7.2 mi (11.5 km) from the heart of Sedgewickville, is a top choice for your stay, based on our traveller data. Other good options for your visit to the area are La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau and Drury Inn & Suites Jackson MO. See all available top hotels, or vacation rentals in Sedgewickville.
What are some of the best holiday rentals that Sedgewickville has to offer?
Greenway Getaway~Charming 3-bedroom, 3 BA home in the heart of Jackson, Missouri: This holiday home rental outside of Sedgewickville comes with air conditioning so that you can feel at home during your trip. Kitchen amenities include a dishwasher, a stovetop and a microwave. See all vacation rentals in Sedgewickville.
If I need to cancel my hotel reservation in Sedgewickville, will I receive a refund?
Yes! You'll find that most hotel bookings are fully refundable as long as you cancel before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your arrival date. If your reservation is non-refundable, you may still be able to cancel and get a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Sedgewickville.
How is it to stay in Sedgewickville?
Those travelling to Sedgewickville will definitely enjoy the sights to see and things to do. There are 80 hotels and other accommodation options in the surrounding area. Find out more about Sedgewickville.
What are the top places to visit in Sedgewickville?
Places to visit in the wider area include Perryville Country Club, National Shrine of Our Lady of the Miraculous Medal and Bollinger Mill State Historic Site. You'll also find Saint Marys Lake and Missouri's National Veterans Memorial in the area. Take a look at what more there is to see and do in Expedia's Sedgewickville guide.
What's the weather like in Sedgewickville?
The hottest months are usually July and August, with an average temperature of 24°C, while the coldest months are January and February, with an average of 4°C. Average annual precipitation for Sedgewickville is 1496 mm.

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