Santo Antonio Holidays

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Your Santo Antonio Holiday

Our Santo Antonio holiday packages are a time-saving and convenient way to plan and reserve your next getaway. Discover the heart and soul of this unique neighbourhood without the hassle of organising it all yourself. Start your trip to Santo Antonio by visiting nearby attractions such as Teatro Amazonas, Amazon Arena and CIGS Zoo. No matter your travel goals or budget, booking your dream Santo Antonio holiday is a cinch with Expedia.

Our guide on where to stay in Santo Antonio

Find the best Santo Antonio areas and neighborhoods for the activities you enjoy most. Learn more about Santo Antonio
Teatro Amazonas - Rio Negro ao fundo - Praça São Sebastião.

Manaus Centro

2 out of top 10 points of interest in this area
4/5(2 area reviews)

Manaus Centro is noteworthy for its theatres, and you can make a stop at top attractions like Teatro Amazonas and Port of Manaus.

Find hotels in Manaus Centro

Our pick of the best Santo Antonio Hotel Deals

Rede Andrade Amazônia

Rede Andrade Amazônia

3 out of 5
Av. Getúlio Vargas 227 Manaus AM
The price is AU$34 per night from 1 June to 2 June
AU$34
1 June - 2 June
includes taxes & fees
8/10 Very Good! (1,008 reviews)
"The hotel was very clean! The staff were very attentive and helpful. The rooms are big and cozy. The breakfast was delicious! The gym and the swimming pool were great. On the whole l would recomnend the Rede Andrade Hotels to anyone who visit Manaus, Brazil... Hugo Vanegas"

Reviewed on 1 May 2026

Rede Andrade Amazônia
Hotel Express Vieiralves

Hotel Express Vieiralves

3 out of 5
Rua Rio Branco, s/n Manaus AM
Fully refundableReserve now, pay when you stay
The price is AU$52 per night from 12 June to 13 June
AU$52
12 June - 13 June
includes taxes & fees
8.4/10 Very Good! (1,009 reviews)
"I loved the breakfast, the cozy room, the staff super polite and helpful. I highly recommend it."

Reviewed on 25 Apr 2026

Hotel Express Vieiralves
Hotel Intercity Manaus

Hotel Intercity Manaus

4 out of 5
Rua Professor Marciano Armond, 544 Manaus AM
Fully refundableReserve now, pay when you stay
The price is AU$101 per night from 7 June to 8 June
AU$101
7 June - 8 June
includes taxes & fees
8.4/10 Very Good! (977 reviews)
"The food was excellent. The ac was ok not really cool the fan didn’t work to well but it did the job"

Reviewed on 11 May 2026

Hotel Intercity Manaus
See all 228 properties in Santo Antonio
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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beach holidays
Beach Holidays
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Frequently asked questions

How much does a Santo Antonio holiday package cost?
Browse and book everything in one place with our Santo Antonio holiday packages, which start from a low . Choose the hotels and flights that match your travel plans. Then, add on one or two experiences or tours for a memorable escape.
How do I get a cheap travel package to Santo Antonio?
If you love amazing deals, bundle your bookings into a Santo Antonio holiday package. Whether you're searching for hotels, flights, tours or rental cars, you can book everything in one place. You'll have ample choice at your fingertips as well. Expedia has more than 550 airlines and 1 000 000 hotels worldwide to choose from. Fly with who you prefer, stay anywhere you like and save a pretty penny — now that's the perfect escape!
Where should I stay in Santo Antonio?
Most visitors who travel to Santo Antonio put both Teatro Amazonas and Amazon Arena on their to-do lists. Why not reserve a hotel close to one of these fantastic attractions?
How far in advance should I book my Santo Antonio holiday?
Your best bet is to book early. Airlines usually release flights nearly 12 months in advance, and this is an ideal opportunity to score some of the lowest prices. Boss just told you to take all your holiday days next month? That's alright! Expedia are never short on fantastic deals to send you on the getaway of your dreams, at an affordable price.
What does an Expedia Santo Antonio travel package include?
Hotels, rental cars and flights — we've got them all. With Expedia, you can shape your Santo Antonio package just how you like it. All you have to do is decide exactly what you need. Once you've made your booking, you can add extras like tours and activities. The more you bundle, the greater the savings!
What should I know before booking a Santo Antonio travel package?
So many places to venture to, so many things to see. With a package, you can cross more of them off your list. Combine your flights, hotels and rental cars and get ready to save.
Can I choose my airline with a Santo Antonio Expedia holiday package?
With a holiday package, you're the boss. Whether you're eager to fly to Santo Antonio in economy or first class, simply pick from the available airline options. Expedia has access to more than 550 partner airlines around the world.
If I'm not able to travel, can I cancel my Santo Antonio holiday package?
If your travel plans in Santo Antonio have been upended, it's a relief to know that it is possible to cancel or amend your booking. If your booking was made in the last 24 hours, you may be able to get a refund. If your booking was made more than 24 hours ago, your hotel, airline or car rental company may impose fees. For more information, check our Customer Service Portal.

Discover the most popular places to visit in Santo Antonio

Teatro Amazonas - Rio Negro ao fundo - Praça São Sebastião.

Teatro Amazonas

5/5(3 reviews)

You can enjoy a show at Teatro Amazonas on your trip to Manaus. Stroll along the riverfront or experience the area's theatre scene.

Teatro Amazonas

Manauara Shopping

4/5(2 reviews)

You can browse for the perfect souvenirs at Manauara Shopping during your trip to Manaus. Wander the riverfront and forests in the area.

Manauara Shopping

Lake Janauari Ecological Park

Explore the great outdoors at Lake Janauari Ecological Park, a lovely green space in Iranduba. While you're in the area, stroll along the riverfront.

Lake Janauari Ecological Park

Activities

Amazon Safari from Manaus

Amazon Safari from Manaus

AU$54
per adult
Amazon Safari from Manaus
Manaus: Half-Day City Tour

Manaus: Half-Day City Tour

AU$75
per adult
100% of travellers recommend
Manaus: Half-Day City Tour
Maroaga Cave

Presidente Figueiredo Tour

AU$135
per adult
Presidente Figueiredo Tour
See all activities in Manaus
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.