Santo Antonio Holidays from AU$5,324

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Your Santo Antonio Holiday

From its shopping to its cafes and culture, there are tons of good reasons to book a holiday package to Santo Antonio. When you need to get away from it all, this commercial neighbourhood has a spot just for you. When it's time to sightsee, you'll find plenty of big-name attractions nearby including Castle of São Jorge, Rossio Square and Lisbon Cathedral. Tick off one or all during your trip to Santo Antonio. Expedia is here to put your travel plans into action. Book your ultimate Santo Antonio holiday today.

The Latest Santo Antonio Holiday Deals

Price found within the past 48 hours. Click for updated prices.
Eurostars Das Letras

Eurostars Das Letras

5 out of 5
Lisbon City Center
Price was AU$5,874, price is now AU$5,324 per person
AU$5,324
per person
24 Dec - 29 Dec
found 1 day ago
Return direct flight included
Doha (DOH) to Lisbon (LIS)
9/10 Wonderful! (1,005 reviews)
Great hotel and staff. Gifted me a bottle of champagne for my birthday

Reviewed on 11 Nov 2025

Corpo Santo Lisbon Historical Hotel

Corpo Santo Lisbon Historical Hotel

5 out of 5
Lisbon City Center
Price was AU$6,849, price is now AU$6,100 per person
AU$6,100
per person
24 Dec - 29 Dec
found 1 day ago
Return direct flight included
Doha (DOH) to Lisbon (LIS)
10/10 Exceptional! (1,006 reviews)
I cannot recommend this hotel enough! Service, location, room all amazing! The breakfast was fresh and so delicious we looked forward to it every morning. The staff went above and beyond to make sure we were comfortable and happy!

Reviewed on 5 Nov 2025

Eurostars Lisboa Baixa

Eurostars Lisboa Baixa

4 out of 5
Lisbon City Center
Price was AU$6,303, price is now AU$5,631 per person
AU$5,631
per person
24 Dec - 29 Dec
found 1 day ago
Return direct flight included
Doha (DOH) to Lisbon (LIS)
9.8/10 Exceptional! (209 reviews)
The room was lovely and spacious. The shower was excellent. The cleaners were particularly good. The room was always immaculate. We really enjoyed our stay. It was the perfect location. We used the metro from the airport and it was so easy and hotel was just a short walk to the station. Would definitely recommend to friends and would stay again.

Reviewed on 10 Nov 2025

Aurea Museum by Eurostars Hotel Company

Aurea Museum by Eurostars Hotel Company

5 out of 5
Lisbon City Center
Price was AU$6,287, price is now AU$5,622 per person
AU$5,622
per person
24 Dec - 29 Dec
found 1 day ago
Return direct flight included
Doha (DOH) to Lisbon (LIS)
9.4/10 Exceptional! (1,013 reviews)
Beautiful hotel, very clean and helpful staff!

Reviewed on 12 Nov 2025

Sofitel Lisbon Liberdade

Sofitel Lisbon Liberdade

5 out of 5
Lisbon City Center
Price was AU$7,141, price is now AU$6,459 per person
AU$6,459
per person
24 Dec - 29 Dec
found 1 day ago
Return direct flight included
Doha (DOH) to Lisbon (LIS)
9/10 Wonderful! (1,005 reviews)
Room climate was hot and barhroom wasn’t kept up very well.

Reviewed on 31 Oct 2025

Santo Antonio Holiday

Our pick of the best Santo Antonio Hotel Deals

Locke de Santa Joana

Locke de Santa Joana

4 out of 5
18 Rua Camilo Castelo Branco, Lisbon
Fully refundableReserve now, pay when you stay
The price is AU$167 per night from 23 Nov to 24 Nov
AU$167
23 Nov - 24 Nov
includes taxes & fees
9.4/10 Exceptional! (1,417 reviews)
Staff was great and room was clean!

Reviewed on 8 Nov 2025

Locke de Santa Joana
HF Fénix Lisboa

HF Fénix Lisboa

4 out of 5
Praca Marques de Pombal, 8, Lisbon
The price is AU$184 per night from 25 Nov to 26 Nov
AU$184
25 Nov - 26 Nov
includes taxes & fees
9/10 Wonderful! (1,004 reviews)
perfect location

Reviewed on 6 Nov 2025

HF Fénix Lisboa
EPIC SANA Marques Hotel

EPIC SANA Marques Hotel

5 out of 5
Avenida Fontes de Pereira de Melo, 8, Lisbon
Fully refundableReserve now, pay when you stay
The price is AU$288 per night from 7 Dec to 8 Dec
AU$288
7 Dec - 8 Dec
includes taxes & fees
9.6/10 Exceptional! (1,251 reviews)
From start to end. My stay at EPIC Sana was nothing short of spectacular. The reception desk(s) was very friendly and helpful, the hotel was beautiful and my room was amazing. I’m not exaggerating when I say that it was one of the nicest and friendliest hotels that I’ve ever stayed in. The doormen, ...

Reviewed on 5 Nov 2025

EPIC SANA Marques Hotel
See all 732 properties in Santo Antonio
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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beach holidays
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Beach Holidays

Discover the most popular places to visit in Santo Antonio

Avenida da Liberdade

Avenida da Liberdade

You can find the perfect gifts to bring home when you visit Avenida da Liberdade, a popular shopping spot in Santo Antonio. Discover the top-notch restaurants in this romantic area or seek out the local tours.

Avenida da Liberdade
Belem Tower featuring general coastal views, a sunset and heritage architecture

Belém Tower

Lisbon constructed a fortification along a waterway to defend its riches. Now access the structure from the shore for lovely views.

Belém Tower
Pena Palace featuring a castle and heritage elements

Pena Palace

This exuberant construction, a former royal retreat set high in the hills of Sintra, features a colorful assortment of turreted towers and domes.

Pena Palace

What to do in Santo Antonio

Hop-On Hop-Off Boat Tour with Optional Bus Tour Combos

Hop-On Hop-Off Bus Combos

AU$50
per adult
Hop-On Hop-Off Bus Combos
The remarkable Pena Palace

Sintra-Cascais-Pena Palace 8-People Small Group Tour from Lisbon

AU$159
per adult
98% of travellers recommend
Sintra-Cascais-Pena Palace 8-People Small Group Tour from Lisbon
Hop-On Hop-Off Bus & Tramcar Tours

Hop-On Hop-Off Bus & Tramcar Tours

AU$67
per adult
80% of travellers recommend
Hop-On Hop-Off Bus & Tramcar Tours
See all activities in Santo Antonio

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.