Santo Antonio Holidays from AU$597

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Your Santo Antonio Holiday

From its shopping to its cafes and culture, there are tons of good reasons to book a holiday package to Santo Antonio. When you need to get away from it all, this commercial neighbourhood has a spot just for you. When it's time to sightsee, you'll find plenty of big-name attractions nearby including Castle of São Jorge, Rossio Square and Lisbon Cathedral. Tick off one or all during your trip to Santo Antonio. Expedia is here to put your travel plans into action. Book your ultimate Santo Antonio holiday today.

The Latest Santo Antonio Holiday Deals

Price found within the past 48 hours. Click for updated prices.
Hotel Ikonik Lisboa

Hotel Ikonik Lisboa

AU$597
per person
14 Nov - 16 Nov
found 13 hours ago
Return direct flight included
Athens (ATH) to Lisbon (LIS)
9.2/10 Wonderful! (1,228 reviews)
gorgeous room, very clean.

Reviewed on 21 Aug 2026

Eurostars Universal Lisboa

Eurostars Universal Lisboa

AU$625
per person
14 Nov - 16 Nov
found 13 hours ago
Return direct flight included
Athens (ATH) to Lisbon (LIS)
9.2/10 Wonderful! (1,331 reviews)
Heritage Avenida Liberdade, a Lisbon Heritage Collection

Heritage Avenida Liberdade, a Lisbon Heritage Collection

Lisbon City Center
AU$800
per person
14 Nov - 16 Nov
found 13 hours ago
Return direct flight included
Athens (ATH) to Lisbon (LIS)
9.8/10 Exceptional! (1,002 reviews)
Hotel Britania Art Deco

Hotel Britania Art Deco

Lisbon City Center
AU$720
per person
14 Nov - 16 Nov
found 13 hours ago
Return direct flight included
Athens (ATH) to Lisbon (LIS)
9.8/10 Exceptional! (1,003 reviews)
Casa Das Janelas Com Vista

Casa Das Janelas Com Vista

Lisbon City Center
AU$600
per person
14 Nov - 16 Nov
found 13 hours ago
Return direct flight included
Athens (ATH) to Lisbon (LIS)
9.4/10 Exceptional! (358 reviews)

Santo Antonio Holiday

Our pick of the best Santo Antonio Hotel Deals

Locke de Santa Joana

Locke de Santa Joana

18 Rua Camilo Castelo Branco Lisbon
Fully refundableReserve now, pay when you stay
AU$182
23 Aug - 24 Aug
includes taxes & fees
9.4/10 Exceptional! (2,017 reviews)
"Our room was so quiet, a very very busy place, but you wouldn’t know it… beautiful cold pool… small but lovely. The breaky choices were fabulous… too good actually.. our room was air conditioned so always comfortable. Position is very accessible to everything we did. Great stay"

Reviewed on 20 Aug 2026

Locke de Santa Joana
EPIC SANA Lisboa Hotel

EPIC SANA Lisboa Hotel

Av. Engenheiro Duarte Pacheco 15 Lisbon
Fully refundableReserve now, pay when you stay
AU$405
6 Sept - 7 Sept
includes taxes & fees
9.6/10 Exceptional! (1,129 reviews)
"Great staff, beautiful property"

Reviewed on 21 Aug 2026

EPIC SANA Lisboa Hotel
Tivoli Avenida Liberdade Lisboa – A Leading hotel of the world

Tivoli Avenida Liberdade Lisboa – A Leading hotel of the world

Avenida Liberdade, 185 Lisbon
Fully refundableReserve now, pay when you stay
AU$580
31 Aug - 1 Sept
includes taxes & fees
9/10 Wonderful! (1,015 reviews)
"This was a good deal. We stayed here upon arriving for a couple of nights then moved to another well regarded hotel. We were sorry we moved! The room was spacious, comfortable, and quiet. The breakfast was delightful. The hotel and amenities were very special. Honestly, you won't get a better bargain ..."

Reviewed on 21 Aug 2026

Tivoli Avenida Liberdade Lisboa – A Leading hotel of the world
See all 687 properties in Santo Antonio
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Santo Antonio attractions

A historic building with a dome and a Louis Vuitton store.

Avenida da Liberdade

9.4/10 (3,467 reviews)
You can find the perfect gifts to bring home when you visit Avenida da Liberdade, a popular shopping spot in Santo Antonio. Discover the charming cafes in this family-friendly area or seek out the local tours.
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A pond surrounded by lush greenery and trees.

Botanical Garden

8.4/10 (800 reviews)
Portugal’s oldest botanical garden is a relaxing getaway from the bustling Lisbon streets and a great vantage point to admire the striking Tower of Belem.
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A coastal cityscape with a prominent cathedral, a bridge, and a river.

Amoreiras Shopping Center

8.0/10 (225 reviews)
You can find the perfect gifts to bring home at Amoreiras Shopping Center during your trip to Campo de Ourique. Amble around this vibrant area's riverfront or experience its fascinating museums.
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A fountain surrounded by trees, with a cityscape in the background.

Miradouro de São Pedro de Alcântara

8.8/10 (13 reviews)
You can learn about the history of Misericórdia with a trip to Miradouro de São Pedro de Alcântara. Amble around this culturally rich area's riverfront or experience its acclaimed art galleries.
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A cobblestone street lined with historic buildings, including a prominent clock tower and a hotel.

Coracao de Jesus

9.4/10 (3 reviews)
You can find out about the history of Santo Antonio with a stop at Coracao de Jesus. Make time for the shops and local tours in this romantic area.
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A grand hall with high ceilings, large columns, and banners hanging from the ceiling.

National Museum of Natural History

8.6/10 (17 reviews)
Learn about the geological makeup of Portugal and see models of the creatures that once roamed the earth at this interactive museum.
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Cinemateca Portuguesa Museum

8.0/10 (3 reviews)
You can spend an afternoon exploring the galleries in Cinemateca Portuguesa Museum in Santo Antonio. Experience the fascinating museums and acclaimed art galleries in this romantic area.
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Iberostar Selection Lisboa

Iberostar Selection Lisboa is just one of the places to see in Santo Antonio, so why not enjoy the other things to explore during your travels? Discover the acclaimed art galleries and shops in this romantic area.
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What to do in Santo Antonio

Castle in Lisbon

Day Trip to Sintra & Cascais with Admission to Pena Palace and Garden Walk

AU$130
per adult
96% of travellers recommend
Day Trip to Sintra & Cascais with Admission to Pena Palace and Garden Walk
Hop-On Hop-Off Boat Tour with Optional Bus Tour Combos

Lisbon Hop-On Hop-Off Packs

AU$46
per adult
Lisbon Hop-On Hop-Off Packs
Belem Tower

Tour Lisbon: Belém Tower, the Cathedral & Parque das Nações

AU$125
per adult
96% of travellers recommend
Tour Lisbon: Belém Tower, the Cathedral & Parque das Nações
See all activities in Santo Antonio

Frequently asked questions

What are the cheapest months to go to Santo Antonio?
December, January and February are the best times to look for cheap Santo Antonio holiday packages. Opting to travel in less busy months means you can usually find lower prices on flights and hotels.
How many days is enough for Santo Antonio?
Generally, a handful of days is enough to visit the major sights during your Santo Antonio holiday. But if you want to have some time to rest or go on day trips, consider extending your itinerary.
Is it worth booking a holiday package to Santo Antonio?
Well known for its shopping, cafes and culture, a Santo Antonio holiday is a hit with all kinds of visitors. Be sure to visit main sights like Medeiros e Almeida Museum and Cinemateca Portuguesa Museum, and consider renting a set of wheels for day trips to discover even more.
How to find the best Santo Antonio package deals?
Bagging a cheap Santo Antonio package deal is a cinch with Expedia. Once you've entered your destination and preferred dates under our "Packages" tab, set your budget range, add some filters and browse what's available. You can tailor your search by "Amenities," "Property type," "Traveller experience" and more. Sort the results by "Price: low to high" to view the most wallet-friendly Santo Antonio package deals. Want a simple trick to get even more savings? Be flexible with your departure dates and consider going away on a weekday, when prices are often lower.
When to book a holiday package to Santo Antonio?
If you're considering a spontaneous Santo Antonio adventure, browse our last-minute deals that can be booked up to one week before you go. Prefer not to wait until the last minute? You can land incredible deals on your flights and hotels by booking well in advance.
How to plan a trip to Santo Antonio?
  1. Choose your travel dates: What you'd like to do in Santo Antonio and your favourite season will help you decide when to get away.
  2. Set your budget: Factor in expenses like food, flights and transportation when working out how much to put aside for your trip to Santo Antonio. Then, select a hotel that suits your budget, whether that's a low-cost option or a swankier retreat.
  3. Decide how many days away: Start by compiling a list of the activities and attractions you want to get to in Santo Antonio. Then, estimate how long you'll need for each, including any travel time.
  4. Bundle your bookings: With your travel dates in place, you can combine your hotels, flights, car rental and more into a customised Santo Antonio holiday package.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.