Santo Antonio Holidays
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Your Santo Antonio Holiday
From its shopping to its cafes and culture, there are tons of good reasons to book a holiday package to Santo Antonio. When you need to get away from it all, this commercial neighbourhood has a spot just for you. When it's time to sightsee, you'll find plenty of big-name attractions nearby including Castle of São Jorge, Rossio Square and Lisbon Cathedral. Tick off one or all during your trip to Santo Antonio. Expedia is here to put your travel plans into action. Book your ultimate Santo Antonio holiday today.
Santo Antonio Holiday
Our pick of the best Santo Antonio Hotel Deals
EXE Liberdade
Great central location, relatively clean
Reviewed on 10 Feb 2026
Locke de Santa Joana
Clean room, had washing machine , staffs are friendly and helpful
Reviewed on 8 Feb 2026
EPIC SANA Marques Hotel
Very friendly and helpful staff
Reviewed on 9 Feb 2026
Discover the most popular places to visit in Santo Antonio
Avenida da Liberdade
You can find the perfect gifts to bring home when you visit Avenida da Liberdade, a popular shopping spot in Santo Antonio. Discover the charming cafes in this family-friendly area or seek out the local tours.
Belém Tower
Lisbon constructed a fortification along a waterway to defend its riches. Now access the structure from the shore for lovely views.
Lisbon Oceanarium
Embark on an aquatic journey through one of the world’s biggest and most diverse aquariums, located right on Lisbon’s scenic oceanfront.
What to do in Santo Antonio
Sintra, Pena Palace, Quinta da Regaleira & Cascais Group Tour
