Photo by Norberto Moctezuma Gomez

Santana Holiday Rentals

Start date: Check-in selected.
To Date
End date: Check-out
  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

In two weeks
In two months
In three months
In four months

Our top choices for Santana holiday rentals

Cottage in Sabana Grande

Nature's Lodge Escape
The price is AU$123
includes taxes & fees
26 Jan - 27 Jan 2026
Nature's Lodge Escape

Apartment in Cabo Rojo

Buye Apartments
3.0 star property
8.0 out of 10, Very good, (24)
"It was outstanding "
United States
Jorge
The price is AU$285
includes taxes & fees
4 Jan - 5 Jan 2026
Buye Apartments
10.0 out of 10, Exceptional, (2)
"So happy we were the first ones to stay at this new cabin rental. The area is beautiful and the sunsets were gorgeous. we couldn’t have been happier with our stay. The cabin is so cozy with a very spacious outdoor fully equipped kitchen. The bed was super comfy and the AC was very cold. We loved watching the sheep grazing on the property. The owners even offer private tours of various places. My only regret is not planning to spend more time here during our Puerto Rico trip. Utuado itself is...
United States
Jose S.
The price is AU$358
includes taxes & fees
2 Jan - 3 Jan 2026
Finca Don Chaguin - Exquisite sunset views in the beautiful mountains of Utuado
3.0 star property
10.0 out of 10, Exceptional, (11)
"The way was everything organized "
United States
Jesus
The price is AU$258
includes taxes & fees
28 Jan - 29 Jan 2026
Palmeras Beach Apartments
9.6 out of 10, Exceptional, (13)
"A beautiful home and a great host! Strongly recommend! "
United States
Brandon C.
The price is AU$441
includes taxes & fees
7 Jan - 8 Jan 2026
The Cozy Càsata: A Unique American-Style Cabin in the Mountains of Puerto Rico

Holiday Home in Cabo Rojo

Blue House Joyuda
3.5 star property
9.4 out of 10, Exceptional, (32)
"Raul and his staff Laura were excellent. They make us feel like home. The pool was neat and clean, refreshing. Highly recommend and the beach and market are pretty close. "
United States
Edwin
The price is AU$235
includes taxes & fees
5 Jan - 6 Jan 2026
Blue House Joyuda
9.8 out of 10, Exceptional, (10)
"Absolutely loved the spot."
United States
Erin D.
The price is AU$428
includes taxes & fees
19 Jan - 20 Jan 2026
Villa Flamingo Cabo Rojo | Buye Beach | Pool |
9.2 out of 10, Wonderful, (23)
"Everything was just like in the photo from the website, interior in a nautical style, silence, tranquility, Caribbean comfort, a full kitchen that allows you to cook something delicious, beaches within walking distance, thank you... Also grateful for the help in solving questions, the answers were instant, thank you..."
United States
Oleg
The price is AU$208
includes taxes & fees
2 Jan - 3 Jan 2026
A few steps away from paradise

Apartment in Lajas

High Tide Guesthouse PR
9.4 out of 10, Exceptional, (24)
"Very convenient for viewing the bioluminescence at La Paguera (which was excellant). Jessica was very quick to respond and helpful with her communications. Place was charming. Easy parking on the street."
United States
Paula
The price is AU$215
includes taxes & fees
3 Jan - 4 Jan 2026
High Tide Guesthouse PR
10.0 out of 10, Exceptional, (10)
"Very peaceful place near la parguera, Guanica beaches and Yauco art murals and coffee shops. "
United States
Eileen
The price is AU$338
includes taxes & fees
6 Jan - 7 Jan 2026
Enjoy a cozy space in a RV Camper w/hot tub, near beaches.
10.0 out of 10, Exceptional, (1)
The price is AU$317
includes taxes & fees
5 Jan - 6 Jan 2026
Cozy 2BR house w/ AC & WiFi in Utuado near Tanama River
10.0 out of 10, Exceptional, (1)
"This place had such a warm and welcoming environment. Beautifully decorated, tasteful, comfortable bed, roomy bathroom. The air conditioning was instant The place is magical. I loved it so much and will definitely return!"
United States
Lori W.
The price is AU$223
includes taxes & fees
28 Jan - 29 Jan 2026
Beach Apartment with Terrace in Playa Santa

Apartment in Cárcel

Boulevard 201
3.0 star property
8.0 out of 10, Very good, (1)
"Lugar centrico"
Mexico
Celinette
The price is AU$251
includes taxes & fees
31 Jan - 1 Feb 2026
Boulevard 201
2.5 star property
The price is AU$244
includes taxes & fees
4 Jan - 5 Jan 2026
Boqueron Beach and Country Cabins
10.0 out of 10, Exceptional, (3)
"We enjoyed our stay very much. Host was very communicative & cordial. Loved the area & would consider staying again. "
United States
Nancy N.
The price is AU$257
includes taxes & fees
1 Jan - 2 Jan 2026
Cozy studio near rest,malls,beaches, attractions, plenty of secure parking.
9.4 out of 10, Exceptional, (3)
"The place was super cute, clean, and cozy. The place was in a quiet street, but still close enough to walk to the restaurants and night life. The host communicated all the necessary information in a tjmely manner, and didn't have any issues. I would definitely stay there again! "
United States
Maria
The price is AU$185
includes taxes & fees
1 Jan - 2 Jan 2026
HighTide Guesthouse Apartments, La Parguera

Mobile Home in Cabo Rojo

Camper Capacidad Hasta 6 Personas
The price is AU$202
includes taxes & fees
7 Jan - 8 Jan 2026
Camper Capacidad Hasta 6 Personas
9.4 out of 10, Exceptional, (10)
"We stayed in Mayaguez to participate in the "Justas" activities and it was excellent. Good location, spacious property with parking. Thanks Gerard!"
United States
Monika O.
The price is AU$324
includes taxes & fees
6 Jan - 7 Jan 2026
Mayaguez spacious 3-bedroom Villa
9.8 out of 10, Exceptional, (6)
"We went there for a basketball tournament so we spent most of our time out of the property but Ill definitely rent it again to be able to enjoy what it has to offer! Beautiful, beautiful place! "
United States
Taína T.
The price is AU$374
includes taxes & fees
18 Jan - 19 Jan 2026
Beach House with Pool in Playa Santa - Casa Perla
10.0 out of 10, Exceptional, (2)
"This place was comfortable clean beautiful and close enough to drive in many directions. I would stay here again. Thank you my family also loved it!"
United States
Lorraine l.
The price is AU$344
includes taxes & fees
13 Jan - 14 Jan 2026
Centrally located , Family and Pet Friendly.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Top Santana Hotel Reviews

Find out more about Santana

Everything you need to know about Santana holiday rentals

Whether you’re excited for the perfect family holiday, a romantic getaway for two, or the ultimate city break, we’ve got the Santana holiday rental for you. At Expedia, you can take your pick from private holiday homes, apartments, cottages, cabins, villas... The list goes on, and on… and on!

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Santana holiday rental for you by simply entering your desired dates. Then check your favourite filters to narrow down your search. 

Santana holiday rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Santana. If you’re looking for a little peace, consider booking during the quieter months, such as  . For more hustle and bustle, you may prefer to visit in . 

Prices vary throughout the year and depend on the property type. Your chosen location and amenities will impact the cost of your trip, too. A Santana holiday rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a holiday rental with multiple bedrooms and shared living spaces to kick back in.  The selection of Santana holiday rentals we have selected for you start as low as AU$166 per night. Entering your travel dates in the search wizard might find you even better deals!

How to find incredible deals on Santana rentals

At Expedia, we put the best Santana holiday rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia. 

To find some top Santana rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Santana holiday.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Santana. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence. 

Frequently asked questions

Are there holiday rentals in Santana?

Yes, there are holiday rentals close to the most popular sights in Santana, or you can select a more secluded option if you're looking for a relaxing stay.

What are some of the best holiday rentals that Santana has to offer?

Blue House Joyuda: This holiday home rental outside of Santana is located near the beach, and has an outdoor pool, a garden and a BBQ to put you at ease in your new surroundings. Kitchen amenities include a fridge, a microwave and a coffee maker.

What can I see and do in Santana?

While exploring the area, visit family-friendly sights like Surf 'N Fun Water Park, or get outside and enjoy nature at Bosque Estatal de Maricao. In the wider area, you’ll find Church of Porta Coeli and Plaza San Pedro.

What are holiday rentals like in Santana?

Holiday rentals are privately owned properties you can book for a few days, or a quick weekend, in Santana. Holiday rentals feature amenities like laundry facilities and kitchens so you'll feel just like you're at home. If you're concerned about a sanitised environment, holiday rentals can offer a sense of seclusion away from shared hotel lifts and busy concierge desks while still allowing you the enjoyment of travel. You'll also have more space in a holiday rental than in a hotel, which makes a holiday rental a great choice for family trips.