Santa Rosa Holiday Rentals

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Our top choices for Santa Rosa holiday rentals

Arcadia Condo Suites

2.5 star property
Costa del Este
9.4 out of 10, Exceptional, (156)
"Everything was great, helpful staff, great room , clean, excellent service!"
United States
Gregory Walter
The price is AU$174
includes taxes & fees
15 Dec - 16 Dec
Arcadia Condo Suites

Boutique Apartments Panama

3.5 star property
Bella Vista
7.6 out of 10, Good, (213)
"The view was amazing and the place was great could stay here again "
United States
Yonnette
Boutique Apartments Panama

Torres de Alba Hotel & Suites

3.5 star property
Bella Vista
8.8 out of 10, Excellent, (482)
"The buffet bar and great customer service. "
United States
Kayhiuska
Torres de Alba Hotel & Suites

Casco View Apartments

3.5 star property
Santa Ana
9.2 out of 10, Wonderful, (52)
"Great stay, would recommend."
United States
Brooke
Casco View Apartments

Las Clementinas

3.5 star property
Casco Viejo
9.4 out of 10, Exceptional, (169)
"Our stay at Las Clementinas was amazing. The ambiance, decor, and central location to all things in Casco Viejo made our trip magical. Not only was the hotel beautiful, the staff was incredibly warm, helpful and welcoming. The restaurant in the hotel was absolutely delicious. I would stay here ten times over. "
United States
Amanda
The price is AU$214
includes taxes & fees
10 Dec - 11 Dec
Las Clementinas

Boutique Apartments Panamá Coco del Mar

3.5 star property
San Francisco
7.4 out of 10, Good, (152)
"Clean room good place to stay "
United States
Gideon
The price is AU$284
includes taxes & fees
10 Dec - 11 Dec
Boutique Apartments Panamá Coco del Mar

La Isabela Suites

3.5 star property
Casco Viejo
10.0 out of 10, Exceptional, (166)
"The room was spotless, the location perfect, and the staff was absolutely superb!"
United States
Gregory
La Isabela Suites

La Cuadra by Wynwood House

3.5 star property
El Chorrillo
9.2 out of 10, Wonderful, (44)
"Love the property. You are right at the start of the nice part of casco viejo but the blocks around it are rough and ugly. The police are very prominent so it's safe but be on alert"
United States
Carlos
The price is AU$233
includes taxes & fees
10 Dec - 11 Dec
La Cuadra by Wynwood House

Yoo Panamá by Boutique Apartments

3.5 star property
Bella Vista
8.2 out of 10, Very good, (48)
"Great location but not enough towels in the room "
United States
Damion
The price is AU$303
includes taxes & fees
10 Dec - 11 Dec
Yoo Panamá by Boutique Apartments

San Francisco by Wynwood House

3.0 star property
San Francisco
9.2 out of 10, Wonderful, (56)
"Clean and walkable location"
United States
Tamera
The price is AU$279
includes taxes & fees
10 Dec - 11 Dec
San Francisco by Wynwood House

ESHEL SUITES PANAMA

2.5 star property
San Francisco
10.0 out of 10, Exceptional, (5)
"Loved the property and the location, it was clean , nice and I really enjoyed my stay there"
United States
Aron
ESHEL SUITES PANAMA

Casa Contemporanea by Wynwood House

4.0 star property
Casco Viejo
8.2 out of 10, Very good, (20)
"Great place!"
United States
Jad
The price is AU$254
includes taxes & fees
10 Dec - 11 Dec
Casa Contemporanea by Wynwood House

Boutique Apartments Atlapa

3.0 star property
San Francisco
8.0 out of 10, Very good, (26)
"I had an excellent stay here ! It was a very amazing the host is an amazing person thank you for making My stay great❤️"
United States
Shamia
Boutique Apartments Atlapa

Yoo Panama & Arts Tower

3.0 star property
Bella Vista
9.4 out of 10, Exceptional, (46)
"Nice stay"
United States
ANGEL
Yoo Panama & Arts Tower

Casa Mallet by Wynwood House

4.0 star property
Casco Viejo
9.8 out of 10, Exceptional, (25)
" It was very relaxing to stay at the historical and cutely renovated apartment. Great aesthetic. Lively apartment, very well decorated! Right the middle of everything in the beautiful town of Casco Veijo. Vibrant lanes, boutique stores, cafes and restaurants near by. We had an amazing time staying for 2 nights at this apartment. "
United States
Navyatha
The price is AU$660
includes taxes & fees
7 Jan - 8 Jan 2026
Casa Mallet by Wynwood House

Casa Love by Wynwood House

3.0 star property
Casco Viejo
8.6 out of 10, Excellent, (18)
"Great apartment on a quiet street slose to everything to see in the old town"
Singapore
Cory Leslie
The price is AU$203
includes taxes & fees
14 Dec - 15 Dec
Casa Love by Wynwood House

La Moderna by Wynwood House

3.0 star property
Casco Viejo
7.4 out of 10, Good, (40)
"The nightlife around there was incredible"
United States
Felix
The price is AU$156
includes taxes & fees
10 Dec - 11 Dec
La Moderna by Wynwood House

Delightful Ocean View

3.5 star property
San Francisco
8.0 out of 10, Very good, (2)
"The apartment was in a good location but most of the pictures in this listing were of the lobby and building. The showerheads in both bathrooms kept moving which caused water to go everywhere, and we only had two pillows on the main bed and one on each twin bed, and the linens were lacking, there is also no outdoor furniture and the apartment is right above the pool which occasionally was noisy. Also there aren’t great instructions to check in or check out. There are better places to stay in...
United States
Laura
Delightful Ocean View

Donovan By Wynwood House

3.0 star property
Casco Viejo
8.4 out of 10, Very good, (45)
"I always love to stay at Wynwood properties in Panama "
United States
Alberto B
The price is AU$199
includes taxes & fees
10 Dec - 11 Dec
Donovan By Wynwood House

Casa La Costa By Wynwood House

3.5 star property
Casco Viejo
8.4 out of 10, Very good, (20)
"Great location. At the border of renovated areas but an extremely go deal for this great property. "
United States
William
The price is AU$241
includes taxes & fees
11 Dec - 12 Dec
Casa La Costa By Wynwood House
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Find out more about Santa Rosa

Everything you need to know about Santa Rosa holiday rentals

Whether you’re excited for the perfect family holiday, a romantic getaway for two, or the ultimate city break, we’ve got the Santa Rosa holiday rental for you. At Expedia, you can take your pick from private holiday homes, apartments, cottages, cabins, villas... The list goes on, and on… and on!

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Santa Rosa holiday rental for you by simply entering your desired dates. Then check your favourite filters to narrow down your search. 

Santa Rosa holiday rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Santa Rosa. If you’re looking for a little peace, consider booking during the quieter months, such as  . For more hustle and bustle, you may prefer to visit in . 

Prices vary throughout the year and depend on the property type. Your chosen location and amenities will impact the cost of your trip, too. A Santa Rosa holiday rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a holiday rental with multiple bedrooms and shared living spaces to kick back in.  The selection of Santa Rosa holiday rentals we have selected for you start as low as AU$156 per night. Entering your travel dates in the search wizard might find you even better deals!

How to find incredible deals on Santa Rosa rentals

At Expedia, we put the best Santa Rosa holiday rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia. 

To find some top Santa Rosa rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Santa Rosa holiday.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Santa Rosa. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence. 

Frequently asked questions

Are there holiday rentals in Santa Rosa?

Yes, there are holiday rentals close to the most popular sights in Santa Rosa, or you can select a more secluded option if you're looking for a relaxing stay.

What are some of the best holiday rentals that Santa Rosa has to offer?

Panama View House – A Hilltop Retreat with Stunning Canal Views: This holiday home rental outside of Santa Rosa has air conditioning and laundry facilities to help you feel perfectly comfortable in your new surroundings.

What can I see and do in Santa Rosa?

Explore the area and family-friendly sights such as Summit Botanical Gardens & Zoo, or get out into nature at a spot like Chagres River. Albrook Shopping Mall and Gamboa Rainforest Resort are a couple of places you'll find in the wider area.

What are holiday rentals like in Santa Rosa?

Holiday rentals are private properties where you can stay for a few weeks, or just a few days, in Santa Rosa. Holiday rentals offer extras such as patios, hot tubs and fire pits so you'll feel right at home. If you're concerned about a sanitised environment, holiday rentals can provide a sense of seclusion away from public hotel lifts and busy front desks while still allowing you the excitement and enjoyment of travel. You'll also get more space in a holiday rental than in a standard hotel, which is another reason why a holiday rental is an attractive choice for a small group gathering.