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Santa Maria Hotels, Guayaquil

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Check prices for these dates

This weekend
25 Sept - 27 Sept
Next weekend
2 Oct - 4 Oct

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Our top choices for Santa Maria hotels

A modern interior with a seating area, a kitchen, and a dining space.

1. Holiday Inn Guayaquil Airport by IHG

Holiday Inn Guayaquil Airport by IHG
3.5 star property
5.5 km from Santa Maria
9.4 out of 10, Exceptional, (1,005 reviews)
"The food was excellent, best hotel food I’ve had in a long time."
United States
David
The price is AU$160
4 Oct - 5 Oct
Holiday Inn Guayaquil Airport by IHG
A modern hotel lobby with a reception desk, seating area, and a large decorative plant.

2. Courtyard by Marriott Guayaquil

Courtyard by Marriott Guayaquil
3.5 star property
Kennedy, 4.9 km from Santa Maria
9.0 out of 10, Wonderful, (1,000 reviews)
"Great locations and wonderful staff.!!"
Canada
Carlos
The price is AU$126
27 Sept - 28 Sept
Courtyard by Marriott Guayaquil
A high-rise hotel interior with multiple floors, large windows, and modern lighting fixtures.

3. Hilton Colon Guayaquil

Hilton Colon Guayaquil
4.5 star property
Kennedy, 4.2 km from Santa Maria
8.8 out of 10, Excellent, (994 reviews)
"I like the location, amenities and staff is very helpful. Also, I felt very safe taking Ubers from the Hotel since is a chain of well known experienced drivers and very friendly"
United States
Marissa
The price is AU$162
24 Oct - 25 Oct
Hilton Colon Guayaquil
An outdoor seating area with wicker chairs and a table, a glass wall with a reflection, and hanging orange lights.

4. Hotel Puerto Pacifico Guayaquil Airport

Hotel Puerto Pacifico Guayaquil Airport
4.0 star property
Garzota, 4.9 km from Santa Maria
8.8 out of 10, Excellent, (287 reviews)
"The staff was very nice and helpful, the room was very clean along with their good smelling towels. Area seemed very safe."
United States
Diana
The price is AU$93
25 Oct - 26 Oct
Hotel Puerto Pacifico Guayaquil Airport
A modern bar area with a bar counter, stools, and a seating area with a table and chairs.

5. Wyndham Garden Guayaquil

Wyndham Garden Guayaquil
3.5 star property
Simón Bolívar, 4.8 km from Santa Maria
9.2 out of 10, Wonderful, (1,001 reviews)
"Best hotel and great location food amazing"
United States
Giselle
The price is AU$127
17 Oct - 18 Oct
Wyndham Garden Guayaquil
A buffet setup with pastries and various food items in jars.

6. Sheraton Guayaquil Hotel

Sheraton Guayaquil Hotel
5.0 star property
Simón Bolívar, 4.8 km from Santa Maria
9.0 out of 10, Wonderful, (688 reviews)
"Breakfast lots of variety, service is good, free shuttle from airport"
Canada
Victoria
The price is AU$153
9 Oct - 10 Oct
Sheraton Guayaquil Hotel
A person sitting by a pool with a stone waterfall feature in the background.

7. Dreamkapture Hostel

Dreamkapture Hostel
2.0 star property
Alborada, 3 km from Santa Maria
8.4 out of 10, Very good, (27 reviews)
"Awesome place to stay for a couple days great staff and affordable prices "
United States
Vance
The price is AU$30
29 Sept - 30 Sept
Dreamkapture Hostel
A modern bar area with a bar counter, seating, and a large window.

8. Wyndham Guayaquil Puerto Santa Ana

Wyndham Guayaquil Puerto Santa Ana
4.5 star property
Puerto Santa Ana, 7.5 km from Santa Maria
9.4 out of 10, Exceptional, (1,004 reviews)
"Great hotel to stay in! Staff was super friendly!"
United States
Isabel
The price is AU$164
27 Sept - 28 Sept
Wyndham Guayaquil Puerto Santa Ana
A reception desk with a marble top and a modern light fixture above it.

9. TRYP by Wyndham Guayaquil Airport

TRYP by Wyndham Guayaquil Airport
4.5 star property
Simón Bolívar, 4.9 km from Santa Maria
9.0 out of 10, Wonderful, (1,000 reviews)
"Everything was great, breakfast was great"
United States
BLANCA
The price is AU$145
16 Oct - 17 Oct
TRYP by Wyndham Guayaquil Airport

10. DC Suites Aeropuerto

DC Suites Aeropuerto
3.0 star property
Simón Bolívar, 5.2 km from Santa Maria
9.0 out of 10, Wonderful, (661 reviews)
"The hotel was very nice and a very helpful staff. Easy on the eyes too."
Canada
Jeff
The price is AU$53
25 Sept - 26 Sept
DC Suites Aeropuerto
An outdoor patio with wicker furniture, a stone wall, and a water feature.

11. Hotel Marcelius

Hotel Marcelius
3.5 star property
Kennedy, 4.7 km from Santa Maria
8.4 out of 10, Very good, (259 reviews)
"👍"
United States
Marcos
The price is AU$93
27 Sept - 28 Sept
Hotel Marcelius
An indoor swimming pool with a tiled edge, surrounded by lounge chairs and a seating area with tables and chairs.

12. Cedros Inn Boutique Hotel

Cedros Inn Boutique Hotel
3.5 star property
Urdesa, 4.6 km from Santa Maria
8.6 out of 10, Excellent, (95 reviews)
"Staff was very helpful and nice. The property was well kept, and well located"
United States
Jazmin
The price is AU$100
25 Sept - 26 Sept
Cedros Inn Boutique Hotel
A spacious indoor area with a central open space surrounded by seating arrangements and a pool.

13. Radisson Hotel Guayaquil

Radisson Hotel Guayaquil
5.0 star property
Kennedy, 4.9 km from Santa Maria
9.2 out of 10, Wonderful, (737 reviews)
"The pool was truly wonderful, offering beautiful views and the perfect water temperature. The food was exceptional as well, and the staff were incredibly helpful."
United States
Yoan
The price is AU$127
4 Oct - 5 Oct
Radisson Hotel Guayaquil
A person in a white robe sitting on a bed with a tray containing breakfast items like fruit, juice, and cereal.

14. MC Suites

MC Suites
3.5 star property
Kennedy, 4.4 km from Santa Maria
8.2 out of 10, Very good, (143 reviews)
"Staff is great and they are pending that you enjoy time in the hotel!"
United States
Sofia
The price is AU$65
26 Sept - 27 Sept
MC Suites
A breakfast table with various foods and a view of a park through a window.

15. Unipark by Oro Verde Hotels

Unipark by Oro Verde Hotels
4.0 star property
Rocafuerte, 8 km from Santa Maria
9.2 out of 10, Wonderful, (1,000 reviews)
"Clean hospitality excellent place to stay. Would come again ."
United States
silvia
The price is AU$115
26 Sept - 27 Sept
Unipark by Oro Verde Hotels
A pool area with lounge chairs, a waterfall, and tropical plants.

16. Iguanazu Bed & Breakfast

Iguanazu Bed & Breakfast
3.5 star property
3 km from Santa Maria
9.2 out of 10, Wonderful, (49 reviews)
"Breakfasts were excellent. Staff went out of their way to accommodate late arrival. "
Canada
Kimberly
The price is AU$163
27 Sept - 28 Sept
Iguanazu Bed & Breakfast
An aerial view of a hotel with a swimming pool surrounded by lush greenery and a decorative garden.

17. Grand Hotel Guayaquil, Centro Histórico.

Grand Hotel Guayaquil, Centro Histórico.
4.0 star property
Rocafuerte, 7.9 km from Santa Maria
9.2 out of 10, Wonderful, (1,009 reviews)
"Nice breakfast setup the pool was fantastic and the room very spacious location was perfect next to everything"
United States
Edwin
The price is AU$115
24 Oct - 25 Oct
Grand Hotel Guayaquil, Centro Histórico.
A building with a traditional architectural style, featuring a prominent entrance with a set of stairs leading up to a double door.

18. Luxva Hotel Boutique

Luxva Hotel Boutique
3.0 star property
Urdesa, 4.7 km from Santa Maria
9.4 out of 10, Exceptional, (182 reviews)
"Love the breakfast menu and security."
United States
Marcela
The price is AU$149
28 Sept - 29 Sept
Luxva Hotel Boutique
A compact kitchen with a stainless steel refrigerator, a built-in oven, and a window with a view of buildings.

19. Suitesecu Rentals Guayaquil

Suitesecu Rentals Guayaquil
4.5 star property
Garzota, 5.1 km from Santa Maria
9.2 out of 10, Wonderful, (21 reviews)
"Great for 1 night in Guayaquil before a morning flight."
Canada
Charles-Olivier
The price is AU$47
27 Sept - 28 Sept
Suitesecu Rentals Guayaquil
A rooftop terrace with outdoor seating, a bar area, and potted plants.

20. Harmonie

Harmonie
2.0 star property
Simón Bolívar, 4.8 km from Santa Maria
9.0 out of 10, Wonderful, (107 reviews)
"It was easy to find and check in. Staff was quick to respond and very helpful. The room was clean and nicely set up."
United States
Karen
The price is AU$61
2 Oct - 3 Oct
Harmonie
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Our guide on where to stay in Santa Maria

Find the best Santa Maria areas for the activities you enjoy most.
A row of colorful colonial buildings with balconies and wooden shutters.

Ecuador

Ecuador might not have many top sights, but C.C. Riocentro Sur and Mall del Sur are two attractions nearby that you can check out.

A colorful outdoor installation with large letters spelling out a word.
Photo by Botak Jon
Open Photo by Botak Jon

Downtown Guayaquil

Travellers come to Downtown Guayaquil for its abundant dining options, and you can see top attractions like Sports Federation of Guayas and Artisan Market while you're in town.

A densely packed urban area with numerous buildings and a prominent tower on a hill.

Puerto Santa Ana

Restaurants and river views are some things travellers note about Puerto Santa Ana. Check out Santa Ana Hill or Numa Pompilio Llona Street while you're familiarising yourself with the larger area.

A lizard on a metal fence.

Kennedy

Unique features of Kennedy include the shopping and restaurants. Make a stop by San Marino Mall or World Trade Center while you're exploring the area.

A densely packed hillside cityscape with colorful buildings and a prominent tower against a sunset sky.

Urdesa

Urdesa is well liked for its restaurants. If you'd like to do some sightseeing in the greater Guayaquil area, you might plan a trip to Alban Borja Commercial Center or San Marino Mall.

Top Santa Maria Hotel Reviews

Recent Reviews in Santa Maria

TRYP by Wyndham Guayaquil Airport

TRYP by Wyndham Guayaquil Airport

10/10 Excellent
"I choose this hotel because they always help me by coordinating everything for my trip, the professional and very friendly staff."
Soraya 1-night trip
Posted 2 days ago
TRYP by Wyndham Guayaquil Airport

Frequently asked questions

When is the best time to go to Santa Maria?
The best time to visit Santa Maria is during the dry season, which runs from May to December, offering pleasant weather for exploring.

During these months, you'll experience less humidity and more sunshine, making it ideal for enjoying outdoor activities and sightseeing. The temperatures are consistently warm but not overly hot, typically ranging from 25°C to 30°C. This period is great for travellers who prefer clear skies and comfortable conditions for their adventures.

For those interested in wildlife, particularly birdwatching, the dry season is especially rewarding as many species are more active and visible.
Can I cancel my hotel reservation on Expedia?
Many Expedia hotel reservations are refundable, provided that you cancel before the hotel's cancellation deadline − this is often within 24 to 48 hours of your scheduled arrival. If you have a non-refundable booking, it might still be possible to receive a refund if you cancel it within 24 hours of booking. Be sure to check your booking confirmation for the exact cancellation policy. For maximum flexibility, use our 'Fully refundable property' filter during your search to find the right Santa Maria hotel for you.
How can I save on a hotel booking in Santa Maria with Expedia?
One Key™—Expedia's free travel rewards program—gives you instant access to discounts with Member Prices on Santa Maria hotels. Plus, you'll earn OneKeyCash™* on eligible bookings to use on future trips. Booking an Expedia hotel and flight package is another great way to save, where bundling can result in significant savings. *Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
How much is the nightly rate for a hotel in Santa Maria?
Hotel prices in Santa Maria often vary, but you can find a great deal on Expedia. Different factors affect nightly hotel rates, such as the time of year or the days of the week you want to book. To find the best deals for your stay, be flexible with your dates and sort search results by 'Price: low to high' for our cheapest rates.