Santa Maria Hotels, Guayaquil

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Our top choices for Santa Maria hotels

NP Hotel & Suites

NP Hotel & Suites
3.0 star property
5.6 km from Santa Maria
The price is AU$72
2 June - 3 June
NP Hotel & Suites

Iguanazu Bed & Breakfast

Iguanazu Bed & Breakfast
3.5 star property
3 km from Santa Maria
9.2 out of 10, Wonderful, (47 reviews)
"A lovely oasis in the city. Very relaxing and friendly service."
United States
Landy
The price is AU$92
24 May - 25 May
Iguanazu Bed & Breakfast

Wyndham Guayaquil Puerto Santa Ana

Wyndham Guayaquil Puerto Santa Ana
4.5 star property
Puerto Santa Ana, 7.5 km from Santa Maria
9.2 out of 10, Wonderful, (1,002 reviews)
"great safe place will be back "
United States
Tracy
The price is AU$180
25 May - 26 May
Wyndham Guayaquil Puerto Santa Ana

Hilton Colon Guayaquil

Hilton Colon Guayaquil
4.5 star property
Kennedy, 4.2 km from Santa Maria
8.6 out of 10, Excellent, (912 reviews)
"The room was excellent, clean, and comfortable. The breakfast that was offered was delicious. Everyone was friendly and helpful."
Canada
NELIDA
The price is AU$155
13 June - 14 June
Hilton Colon Guayaquil

Holiday Inn Guayaquil Airport by IHG

Holiday Inn Guayaquil Airport by IHG
3.5 star property
5.5 km from Santa Maria
9.4 out of 10, Exceptional, (1,006 reviews)
"Great hotel, located close to the airport. Staff was friendly, and we would stay there again. "
Canada
Yadira
The price is AU$152
31 May - 1 June
Holiday Inn Guayaquil Airport by IHG

NCG Suite 5

NCG Suite 5
2.5 star property
4.3 km from Santa Maria
10.0 out of 10, Exceptional, (3 reviews)
"loved everything "
United States
Betty
The price is AU$49
7 June - 8 June
NCG Suite 5

NCG Suite 3

NCG Suite 3
2.5 star property
4.4 km from Santa Maria
The price is AU$59
21 May - 22 May
NCG Suite 3

Hotel del Parque

Hotel del Parque
4.5 star property
7 km from Santa Maria
9.8 out of 10, Exceptional, (114 reviews)
"Breakfast excellent"
United States
Priscilla
The price is AU$556
20 June - 21 June
Hotel del Parque

Casa Veranda

Casa Veranda
2.5 star property
8.9 km from Santa Maria
The price is AU$40
3 June - 4 June
Casa Veranda

Hotel La Ria Durán

Hotel La Ria Durán
3.0 star property
9.8 km from Santa Maria
7.4 out of 10, Good, (20 reviews)
"Muy buena experiencia"
Ecuador
HERNAN
The price is AU$67
28 May - 29 May
Hotel La Ria Durán

NCG Suite Samanes 3

NCG Suite Samanes 3
2.5 star property
4.2 km from Santa Maria
The price is AU$47
7 June - 8 June
NCG Suite Samanes 3

Guayacan Apart Hotel

Guayacan Apart Hotel
2.0 star property
Downtown Guayaquil, 7.6 km from Santa Maria
The price is AU$55
21 May - 22 May
Guayacan Apart Hotel

Oro Verde Guayaquil

Oro Verde Guayaquil
5.0 star property
Downtown Guayaquil, 6.9 km from Santa Maria
9.6 out of 10, Exceptional, (1,000 reviews)
"Great place to stay"
United States
IVAN
The price is AU$120
31 May - 1 June
Oro Verde Guayaquil

Hotel Río Guayas by Art Hotels Ecuador

Hotel Río Guayas by Art Hotels Ecuador
4.0 star property
Las Peñas, 7.9 km from Santa Maria
10.0 out of 10, Exceptional, (3 reviews)
"The staff was very friendly and helpful. The hotel is new and modern, it is a good place to relax and work. "
United States
Richard
The price is AU$484
26 May - 27 May
Hotel Río Guayas by Art Hotels Ecuador

Departamentos en la Garzota

Departamentos en la Garzota
4.5 star property
Garzota, 3.9 km from Santa Maria
The price is AU$42
28 May - 29 May
Departamentos en la Garzota

Hostal Macaw

Hostal Macaw
3.0 star property
Kennedy, 4.6 km from Santa Maria
10.0 out of 10, Exceptional, (9 reviews)
"Wonderful hosts and felt like home "
United States
Tina
The price is AU$99
21 May - 22 May
Hostal Macaw

NCG Suite Samanes 2

NCG Suite Samanes 2
3.0 star property
4.3 km from Santa Maria
8.8 out of 10, Excellent, (3 reviews)
"Propiedad segura, ordenada, limpia y tranquila."
Mexico
Shirley
The price is AU$46
20 June - 21 June
NCG Suite Samanes 2

Sheraton Guayaquil Hotel

Sheraton Guayaquil Hotel
5.0 star property
Simón Bolívar, 4.8 km from Santa Maria
9.0 out of 10, Wonderful, (648 reviews)
"The food was delicious the staff was very friendly I recommend this hotel "
Canada
Monica
The price is AU$157
22 May - 23 May
Sheraton Guayaquil Hotel

DC Suites Aeropuerto

DC Suites Aeropuerto
3.0 star property
Simón Bolívar, 5.2 km from Santa Maria
9.0 out of 10, Wonderful, (626 reviews)
"Lovely, small, family run hotel. Nothing fancy but excellent price, clean and the staff is very helpful."
United States
Patricia
The price is AU$50
21 May - 22 May
DC Suites Aeropuerto

TRYP by Wyndham Guayaquil Airport

TRYP by Wyndham Guayaquil Airport
4.5 star property
Simón Bolívar, 4.9 km from Santa Maria
9.0 out of 10, Wonderful, (1,001 reviews)
"Great hotel, clean and comfortable. Food was really good as well. Highly recommended"
United States
Magna
The price is AU$143
24 May - 25 May
TRYP by Wyndham Guayaquil Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Our guide on where to stay in Santa Maria

Find the best Santa Maria areas for the activities you enjoy most.

Ecuador

Ecuador might not have many top sights, but C.C. Riocentro Sur and Mall del Sur are two attractions nearby that you can check out.

Downtown Guayaquil

Travellers come to Downtown Guayaquil for its abundant dining options, and you can see top attractions like Central Market and Sports Federation of Guayas while you're in town.

Puerto Santa Ana

Restaurants and river views are some things travellers note about Puerto Santa Ana. Check out Santa Ana Hill or Numa Pompilio Llona Street while you're familiarising yourself with the larger area.

Kennedy

Unique features of Kennedy include the shopping and restaurants. Make a stop by San Marino Mall or World Trade Center while you're exploring the area.

Urdesa

Urdesa is well liked for its restaurants. If you'd like to do some sightseeing in the greater Guayaquil area, you might plan a trip to Alban Borja Commercial Center or World Trade Center.

Top Santa Maria Hotel Reviews

Frequently asked questions

What is Santa Maria like?
Travellers are sure to enjoy a stay in Guayaquil's Santa Maria neighbourhood.
If I need to cancel my hotel reservation in Santa Maria, will I receive a refund?
Yes, you'll find most room reservations are fully refundable if cancelled before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you booked a non-refundable reservation, it may still be possible to cancel it and get a refund within 24 hours of your booking. Add your dates and click on "Search", then you can filter by "fully refundable" to view the best deals in Santa Maria.
What can I see and do in this Guayaquil neighbourhood?
Salón de Eventos Rubi, City Mall and Guayaquil Parrot are just a few of the places to visit in and around Santa Maria. La Rotonda Shopping Center and Santa Ana Port are also worth a visit when you're out sightseeing in Guayaquil.