Search Santa Isabel hotels

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
24 Apr - 25 Apr
Tomorrow
25 Apr - 26 Apr
This weekend
24 Apr - 26 Apr
Next weekend
1 May - 3 May

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Santa Isabel hotels

View from property

Cabañas Isla Nubesidub San Blas

Cabañas Isla Nubesidub San Blas
2.0 star property
Narganá
The price is AU$590
includes taxes & fees
11 May - 12 May
Cabañas Isla Nubesidub San Blas
Exterior

Cabañas Nalunega San Blas

Cabañas Nalunega San Blas
2.0 star property
Narganá
The price is AU$546
includes taxes & fees
13 May - 14 May
Cabañas Nalunega San Blas
Property grounds

Cabins on paradise San Blas island

Cabins on paradise San Blas island
2.0 star property
Narganá
The price is AU$414
includes taxes & fees
25 Apr - 26 Apr
Cabins on paradise San Blas island
Exterior

Cocoloco - Catamaran Lagoon 52F SAN BLAS

Cocoloco - Catamaran Lagoon 52F SAN BLAS
3.0 star property
Narganá
The price is AU$3,014
includes taxes & fees
28 Apr - 29 Apr
Cocoloco - Catamaran Lagoon 52F SAN BLAS
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Learn more about Santa Isabel

Explore pristine beaches along Santa Isabel's coastline where local fishermen can take you to nearby coral reefs for snorkelling. Hike through lush rainforest trails to spot colourful birds, then visit the town's central plaza where vendors sell fresh tropical fruits and handcrafted souvenirs.

See all hotels in Santa Isabel
Scenic Coiba Island Aerial View

Top Santa Isabel Hotel Reviews

Recent Reviews in Santa Isabel

Caribbean getaway: beach cottage just on the sand

Caribbean getaway: beach cottage just on the sand

6/10 Okay
"It’s nice directly on the beach. The street to the cottage is not paved. Tv wasn’t working and no hot water the 2nd day."
Khalil 3-night trip
Posted 3 days ago
Caribbean getaway: beach cottage just on the sand

More cheap accommodation in Santa Isabel

Cabins on paradise San Blas island

Cabins on paradise San Blas island

9.587566, -78.879820 Narganá San Blas
The price is AU$414 per night from 25 Apr to 26 Apr
AU$414
25 Apr - 26 Apr
includes taxes & fees

Frequently asked questions

What's the best place to stay in Santa Isabel?
Located 21.7 mi (34.8 km) from the heart of Santa Isabel, Private Ocean-Front Cabin with private bathroom on San Blas Island is a top choice for your stay, based on our traveller data. Two other choices for your visit to the area are Cocoloco - Catamaran Lagoon 52F SAN BLAS and Paradise Over the Water Cabins in San Blas. See all available top hotels, or vacation rentals in Santa Isabel.
What are some of the best holiday rentals that Santa Isabel has to offer?
Caribbean Haven Of Nature 'Preci Beach': This holiday home rental outside of Santa Isabel is located on the beach, and has an outdoor pool, a fireplace and a BBQ to put you at ease in your new surroundings. It has 4 bedrooms, as well as a kitchen with a fridge, a stovetop and a microwave, so that you can cook with friends or family. It offers a balcony, a garden and a selection of games so that you can immerse yourself in your holiday. See all vacation rentals in Santa Isabel.
If I need to cancel my hotel reservation in Santa Isabel, will I receive a refund?
Yes, the majority of hotel bookings are fully refundable as long as you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you have a non-refundable reservation, it may still be possible to cancel it and get a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Santa Isabel.
What is staying in Santa Isabel like?
Visitors can enjoy all that Santa Isabel has to offer, including its parks. There are 40 hotels and other accommodation options in the surrounding area. Find out more about Santa Isabel.
What are the top places to visit in Santa Isabel?
Places to visit in the wider area include Chagres National Park, Porvenir Museum and Museum. Take a look at what more there is to see and do in Expedia's Santa Isabel guide.
What's the weather like in Santa Isabel?
The hottest months are usually June and September, with an average temperature of 27°C, while the coldest months are February and March, with an average of 26°C. The rainiest months in Santa Isabel are October, August, July and November, with each month seeing an average of 310 mm of rainfall.