Santa Cruz Hotels, Querétaro

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Our top choices for Santa Cruz hotels

Dos Patios Querétaro Curamoria Collection

Dos Patios Querétaro Curamoria Collection
3.5 star property
Santa Cruz
8.8 out of 10, Excellent, (128)
"Spacious and clean room. Great service from Valet employees. "
United States
Alfredo
The price is AU$183
includes taxes & fees
8 Jan - 9 Jan 2026
Dos Patios Querétaro Curamoria Collection

Hotel Boutique Casa Altamira

Hotel Boutique Casa Altamira
3.5 star property
Santa Cruz
8.8 out of 10, Excellent, (358)
"Very nice boutique hotel in one of the city center’s main dinning zones. The rooms are new and clean, the parking is good and the neighborhood is pretty"
United States
Ulises
Hotel Boutique Casa Altamira

Casa Brunella Hotel Boutique

Casa Brunella Hotel Boutique
3.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (233)
"Unique boutique hotel with eccentric decor and spacious room. Centrally located "
United States
Elsa
The price is AU$143
includes taxes & fees
28 Dec - 29 Dec
Casa Brunella Hotel Boutique

Mesón de San Andrés

Mesón de San Andrés
3.0 star property
Santa Cruz
9.2 out of 10, Wonderful, (115)
"Love it! "
United States
EFREN
The price is AU$97
includes taxes & fees
28 Dec - 29 Dec
Mesón de San Andrés

Hotel Suites Sofia

Hotel Suites Sofia
3.0 star property
Santa Cruz
8.4 out of 10, Very good, (46)
"Perfect place for our needs"
United States
Joseph
The price is AU$124
includes taxes & fees
28 Dec - 29 Dec
Hotel Suites Sofia

Hotel Casa Miranda

Hotel Casa Miranda
2.0 star property
Santa Cruz
9.0 out of 10, Wonderful, (4)
"La atencion es excelente, no asi las instalaciones. El salir de la habitacion para el baño y que este tapado no es muy buena experiencia. Le falta identificacion en la parte de afuera, son aspectos a mejorar "
Mexico
FERNANDO
The price is AU$76
includes taxes & fees
9 Jan - 10 Jan 2026
Hotel Casa Miranda

Casa Realm

Casa Realm
3.0 star property
Santa Cruz
9.4 out of 10, Exceptional, (28)
"Great location 👌 "
United States
Crispin
The price is AU$83
includes taxes & fees
29 Dec - 30 Dec
Casa Realm

Hotel Úrsula Concept

Hotel Úrsula Concept
3.0 star property
Santa Cruz
8.6 out of 10, Excellent, (14)
"It is very clean, the bed was great and all in an historic home that has been converted to a charming family run boutique quality hotel. It is very close to an historic church with its huge plaza filled with families and activities and comfortable benches."
United States
Steven
The price is AU$150
includes taxes & fees
1 Jan - 2 Jan 2026
Hotel Úrsula Concept

Hotel & Spa La Mansión del Burro Azul

Hotel & Spa La Mansión del Burro Azul
3.5 star property
Santa Cruz
8.4 out of 10, Very good, (442)
"The place is absolutely beautiful and original. "
United States
Martha
The price is AU$86
includes taxes & fees
1 Jan - 2 Jan 2026
Hotel & Spa La Mansión del Burro Azul

Hotel Meson de Isabel

Hotel Meson de Isabel
3.0 star property
Santa Cruz
7.4 out of 10, Good, (60)
"Good place but for the price definitely not worth it"
United States
Manuel
Hotel Meson de Isabel

Cinco de Mayo Hotel

Cinco de Mayo Hotel
2.5 star property
Santa Cruz
7.6 out of 10, Good, (310)
"Kind of an unbeatable location in the historic center of Queretaro. Simple, clean, decent value. "
United States
Shaun
The price is AU$47
includes taxes & fees
28 Dec - 29 Dec
Cinco de Mayo Hotel

Hotel Casa Once

Hotel Casa Once
3.5 star property
Centro Histórico, 0.5 km from Santa Cruz
9.6 out of 10, Exceptional, (288)
"Amazing hotel "
United States
lizette
The price is AU$156
includes taxes & fees
29 Dec - 30 Dec
Hotel Casa Once

Hotel Patio Santiago

Hotel Patio Santiago
4.5 star property
Centro Histórico, 0.6 km from Santa Cruz
9.4 out of 10, Exceptional, (406)
"Staff was pleasant, rooms were clean and modern, and it was in a walkable area. It’s a beautiful and relatively new hotel, and a very relaxed stay,"
United States
Alondra
The price is AU$232
includes taxes & fees
20 Jan - 21 Jan 2026
Hotel Patio Santiago

La Casa de la Marquesa

La Casa de la Marquesa
4.0 star property
Centro Histórico, 1 km from Santa Cruz
8.8 out of 10, Excellent, (560)
"Unbelievable place to stay Love it "
United States
maribel
The price is AU$195
includes taxes & fees
1 Jan - 2 Jan 2026
La Casa de la Marquesa

La Casa del Atrio

La Casa del Atrio
3.5 star property
Centro Histórico, 1.1 km from Santa Cruz
9.6 out of 10, Exceptional, (474)
"Charming hotel in a historic old building right in the center of town. The staff was super helpful and courteous. We loved our stay."
United States
Prabuddha
The price is AU$150
includes taxes & fees
28 Dec - 29 Dec
La Casa del Atrio

Hotel Hércules

Hotel Hércules
4.0 star property
Hércules, 2.8 km from Santa Cruz
9.4 out of 10, Exceptional, (184)
"Beautiful hotel! "
France
Julio Cesar
The price is AU$325
includes taxes & fees
28 Dec - 29 Dec
Hotel Hércules

Mesón de Santa Rosa Luxury Hotel

Mesón de Santa Rosa Luxury Hotel
4.0 star property
Centro Histórico, 0.6 km from Santa Cruz
8.4 out of 10, Very good, (622)
"Excelente hotel"
Mexico
Mireya
Mesón de Santa Rosa Luxury Hotel

Gran Hotel de Querétaro

Gran Hotel de Querétaro
3.5 star property
Centro Histórico, 0.9 km from Santa Cruz
9.0 out of 10, Wonderful, (1001)
"Great location and easy access to everything in the downtown area"
United States
Hector
The price is AU$174
includes taxes & fees
30 Dec - 31 Dec
Gran Hotel de Querétaro

Grand Fiesta Americana Queretaro

Grand Fiesta Americana Queretaro
5.0 star property
2.4 km from Santa Cruz
9.4 out of 10, Exceptional, (1001)
"Excelente "
Mexico
Jorge
The price is AU$283
includes taxes & fees
9 Jan - 10 Jan 2026
Grand Fiesta Americana Queretaro

Casa Santiago Hotel Boutique

Casa Santiago Hotel Boutique
3.5 star property
Centro Histórico, 0.7 km from Santa Cruz
9.4 out of 10, Exceptional, (198)
"Excelente "
United States
Hector
Casa Santiago Hotel Boutique
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Our guide on where to stay in Santa Cruz

Find the best Santa Cruz areas for the activities you enjoy most.

Downtown Querétaro

Downtown Querétaro is known for its ample dining options, and you can make a stop by Zenea Garden and Plaza de Armas while in the area.

Juriquilla

Juriquilla is noteworthy for its restaurants, and you can make a stop at top attractions like Plaza Juriquilla and Plaza Ubika.

Centro Histórico

Unique features of Centro Histórico include the historical sites and museums. Make a stop by Zenea Garden or Plaza de Armas while you're exploring the area.

Jurica

Jurica is noteworthy for its shopping, and you can make a stop at top attractions like Antea Lifestyle Center and Urban Center Shopping Mall.

Downtown Tequisquiapan

You'll enjoy the monuments and shopping in Downtown Tequisquiapan. You might want to make time for a stop at Tequisquiapan Handicraft Market or La Pila Park.

Top Santa Cruz Hotel Reviews

Frequently asked questions

What is Santa Cruz like?
Travellers to Querétaro's Santa Cruz neighbourhood will be sure to enjoy a stay here. Are you looking for Santa Cruz travel tips? Make sure that you visit Aqueduct of Santiago de Querétaro and Templo y Convento de la Santa Cruz while you're in the neighbourhood.
Where is the best place to stay in Santa Cruz?
Based on Expedia customer reviews, Hotel Boutique Casa Altamira is the highest ranked property in Santa Cruz. This hotel is a short 13-minute walk from Aqueduct of Santiago de Querétaro, and it offers free parking and free WiFi. Other top choices in the neighbourhood include Hotel & Spa La Mansión del Burro Azul and Hotel Suites Sofia.
How many hotels are there in the Santa Cruz area?
Expedia has 46 hotels and other accommodation options in Santa Cruz to choose from, making this an ideal home base for exploring the greater Querétaro area.
If I need to cancel my hotel reservation in Santa Cruz, will I receive a refund?
Yes, the majority of hotel bookings are fully refundable as long as you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If your reservation is non-refundable, you might still have the option to cancel and get a refund within a 24-hour period of your booking. Enter dates in and click on "Search", then you can filter by "fully refundable" to get the best options available in Santa Cruz.
What is there to do around this Querétaro neighbourhood?
Explore Santa Cruz's landmarks such as Aqueduct of Santiago de Querétaro, Templo y Convento de la Santa Cruz and Arches Viewpoint and learn about the local history. You could also plan a visit to Convent and Temple of Santa Cruz or Querétaro Contemporary Art Museum while you're in the neighbourhood. Plaza de Los Fundadores, Casa de la Zacatecana Museum and Ignacio Mena Rosales House of Culture are just a few of the places to visit in and around Santa Cruz. Plaza de Armas and Querétaro Regional Museum are also worth a visit when you're out sightseeing in Querétaro.

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