Iglesia de Nuestra Señora de Santa Ana, aldea Santa Ana en Antigua Guatemala.

Santa Ana Hotels, Antigua Guatemala

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Our top choices for Santa Ana hotels

La guarida del caudillo

La guarida del caudillo
1.0 star property
Santa Ana
The price is AU$44
includes taxes & fees
19 June - 20 June
La guarida del caudillo

Hostal Casa Buho

Hostal Casa Buho
3.0 star property
Santa Ana
8.8 out of 10, Excellent, (25 reviews)
"This place has two parts, the hotel and a hostel, I stayed in the private room of the hostel part, it wasn’t very good, but the whole place is very nice, like an oasis with a lot of plants, the hotel Part would be very nice."
United States
SUSAN
The price is AU$62
includes taxes & fees
22 June - 23 June
Hostal Casa Buho

Casa Buho B&B

Casa Buho B&B
3.0 star property
Santa Ana
9.2 out of 10, Wonderful, (53 reviews)
"Beautiful hotel with clean rooms and friendly staff. The only downsides are the distance to the center (a 30-minute walk) and the chickens and peacocks screaming early in the morning"
United States
Patrick
The price is AU$64
includes taxes & fees
21 June - 22 June
Casa Buho B&B

Finca San Cayetano

Finca San Cayetano
4.0 star property
15 km from Santa Ana
9.4 out of 10, Exceptional, (24 reviews)
"Highly recommendable for the best view of the volcanoe at nightfall and the restaurant has all you need"
United States
Romilio
The price is AU$200
includes taxes & fees
19 July - 20 July
Finca San Cayetano

Kawilal Hotel

Kawilal Hotel
3.5 star property
13.9 km from Santa Ana
9.0 out of 10, Wonderful, (144 reviews)
"Great place to spend some family vacations. Good staff, really good breakfast option. The food (lunch and dinner) a little bit expensive."
United States
David
The price is AU$197
includes taxes & fees
14 July - 15 July
Kawilal Hotel

Le Suisse Spa

Le Suisse Spa
3.0 star property
6.8 km from Santa Ana
8.6 out of 10, Excellent, (32 reviews)
"Peaceful quiet and clean and the staff so nice 10/10"
United States
Otto francklin
The price is AU$159
includes taxes & fees
19 June - 20 June
Le Suisse Spa

Tikal Futura Hotel & Convention Center

Tikal Futura Hotel & Convention Center
4.5 star property
20.1 km from Santa Ana
9.2 out of 10, Wonderful, (1,029 reviews)
"Great food, rooms are clean!!"
United States
Rossana
The price is AU$188
includes taxes & fees
12 July - 13 July
Tikal Futura Hotel & Convention Center

Mestizo Cortijo

Mestizo Cortijo
3.0 star property
4.3 km from Santa Ana
8.8 out of 10, Excellent, (135 reviews)
"Beautiful property, spacious rooms, great views, amazing breakfast, friendly staff"
United States
Ligia
The price is AU$198
includes taxes & fees
21 June - 22 June
Mestizo Cortijo

Barceló Guatemala City

Barceló Guatemala City
4.5 star property
22.7 km from Santa Ana
9.2 out of 10, Wonderful, (3,303 reviews)
"Great location, always great stay!"
United States
Roberto
The price is AU$218
includes taxes & fees
5 July - 6 July
Barceló Guatemala City

L Aurora Inn

L Aurora Inn
3.0 star property
21 km from Santa Ana
9.0 out of 10, Wonderful, (157 reviews)
"The best hotel!"
United States
Krisia
The price is AU$129
includes taxes & fees
22 June - 23 June
L Aurora Inn

Casa Aurora

Casa Aurora
3.0 star property
20.9 km from Santa Ana
8.8 out of 10, Excellent, (206 reviews)
"It was a really nice place enjoyed staying"
United States
Santos
The price is AU$95
includes taxes & fees
19 June - 20 June
Casa Aurora

Ole España

Ole España
2.5 star property
20.8 km from Santa Ana
9.4 out of 10, Exceptional, (35 reviews)
"I liked the breakfast and clean area"
United States
Juan
The price is AU$59
includes taxes & fees
19 June - 20 June
Ole España

Volcania

Volcania
3.0 star property
2 km from Santa Ana
The price is AU$168
includes taxes & fees
25 June - 26 June
Volcania

Hilton Guatemala City

Hilton Guatemala City
4.5 star property
25.9 km from Santa Ana
8.6 out of 10, Excellent, (732 reviews)
"The property is beautiful and unique. I really felt at home so beautiful and comfortable."
United States
Olga
The price is AU$163
includes taxes & fees
29 June - 30 June
Hilton Guatemala City

Hotel Vista Quince

Hotel Vista Quince
5.0 star property
25.5 km from Santa Ana
8.8 out of 10, Excellent, (279 reviews)
"Very clean room , great staff great location"
United States
Kelly
The price is AU$202
includes taxes & fees
19 June - 20 June
Hotel Vista Quince

In & Out Hotel

In & Out Hotel
3.0 star property
20.9 km from Santa Ana
8.6 out of 10, Excellent, (874 reviews)
"We love staying atbthe In and Out, rooms have AC, very clean, great breakfast and a very reasonable price."
United States
Julian
The price is AU$86
includes taxes & fees
23 June - 24 June
In & Out Hotel

Good Hotel Guatemala City

Good Hotel Guatemala City
3.0 star property
23.9 km from Santa Ana
9.4 out of 10, Exceptional, (353 reviews)
"Super convenient hotel near the airport and some restaurants. Very comfortable beds and really nice staff."
United States
penelope
The price is AU$180
includes taxes & fees
3 July - 4 July
Good Hotel Guatemala City

AC Hotel by Marriott Guatemala City

AC Hotel by Marriott Guatemala City
4.0 star property
26.4 km from Santa Ana
8.6 out of 10, Excellent, (1,000 reviews)
"The staff at the hotel is very friendly and helpful. Location is great and has access to great restaurants and stores without having to drive. Beautiful view of the city. Parking was included and very easy to get to. Overall, a great hotel."
United States
Astrid
The price is AU$222
includes taxes & fees
17 July - 18 July
AC Hotel by Marriott Guatemala City

The Westin Camino Real, Guatemala

The Westin Camino Real, Guatemala
4.5 star property
23 km from Santa Ana
9.4 out of 10, Exceptional, (1,000 reviews)
"Excellent hotel, excellent food. "
United States
Elsa J
The price is AU$233
includes taxes & fees
19 July - 20 July
The Westin Camino Real, Guatemala

Adriatika Hotel & Residence

Adriatika Hotel & Residence
4.5 star property
21.9 km from Santa Ana
9.4 out of 10, Exceptional, (1,018 reviews)
"It was the perfect stay to end a long trip, outstanding room, great breakfast"
United States
Braulio
The price is AU$166
includes taxes & fees
12 July - 13 July
Adriatika Hotel & Residence
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Our guide on where to stay in Santa Ana

Find the best Santa Ana areas for the activities you enjoy most.

Historic Center

If you're spending some time in Historic Center, Central Park and Santa Catalina Arch are top sights worth seeing.

Barrio de La Concepción

While visiting Barrio de La Concepción, you might make a stop by sights like Casa Santo Domingo Museum and Jade Maya Factory and Museum.

Top Santa Ana Hotel Reviews

Frequently asked questions

What's it like in Santa Ana?
Travellers to the Santa Ana neighbourhood in Antigua Guatemala will be sure to enjoy their stay.
What's a favourite place to stay in Santa Ana?
Based on our traveller data, Casa Buho B&B is one of the top choices for your stay in Santa Ana. This hotel offers a restaurant and free parking.
How many hotels will I be able to find in Santa Ana?
If you're searching for places to stay in Antigua Guatemala, choose from one of Expedia's 14 hotels and other accommodation options in Santa Ana.
If I need to cancel my hotel reservation in Santa Ana, will I receive a refund?
Yes! You'll find that most hotel reservations are fully refundable provided that you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you booked a non-refundable reservation, it may still be possible to cancel it and be given a refund within 24 hours of your booking. Enter your dates, click on "Search", then use the "fully refundable" filter to view top deals in Santa Ana.
What are the top things to see and do in Santa Ana?
House of the Giants, Santa Clara Convent and Jade Maya Factory and Museum are just a few of the places to visit in and around Santa Ana. While you're out sightseeing in Antigua Guatemala, make sure that you visit other sights such as Tanque La Unión or Museo del Hermano Pedro.