
San Lorenzo Holidays
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Your San Lorenzo Holiday
Lock in a holiday package to San Lorenzo and immerse yourself in everything this inner city neighbourhood has to offer. With a reputation for bars and pubs, markets and cafes, your next unforgettable adventure can be found right here. Your trip to San Lorenzo wouldn't be complete without stopping by big-name attractions nearby such as Cathedral of Santa Maria del Fiore, Ponte Vecchio and Uffizi Gallery. Expedia can help you turn your ideal San Lorenzo holiday into reality, whatever your travel plans or budget.
Our guide on where to stay in San Lorenzo

Historic Centre of Florence
Lose yourself in the Renaissance charm of Florence’s old town, where masterpieces by Brunelleschi and Giotto line up alongside cafés, gelato shops and trattorias.

Duomo
Visitors to Duomo rave about its fascinating museums, stunning cathedral and popular shops. You might also want to make some time to see Piazza del Duomo or Piazza di Santa Maria Novella while you're exploring the neighbourhood.

Santa Maria Novella
Enjoy the popular shops in Santa Maria Novella. Piazza di Santa Maria Novella is a worthwhile stop, and you can jump on the metro at Porta al Prato - Leopolda Tram Stop or Fratelli Rosselli Tram Stop to see more of Porta al Prato.

San Giovanni
If you're spending some time in San Giovanni, Piazza della Repubblica and Via de' Calzaiuoli are top sights worth seeing.

Santa Croce
Santa Croce is known for its interesting museums, and you can plan a trip to Basilica of Santa Croce and Piazza Santa Croce while you're in town.
Our pick of the best San Lorenzo Hotel Deals

Plus Florence - Hostel
"Recommend you experience the two breakfast options available on site. No discount if you pay in advance. Make sure you ask the front desk how to use the washer and dryer."
Reviewed on 20 Sept 2026

The Social Hub Florence Lavagnini

IQ Hotel Firenze
"Property is about 20 minute walk from the Duomo which is where all the action is. Had it been closer I would give it a 5 star. Some people at the front desk were nice, some very curt. My room was not ready when I got there a bit early. They said they would call me when the room was ready, never heard ..."
Reviewed on 21 Sept 2026
Frequently asked questions
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Stay near popular San Lorenzo attractions

Central Market

Piazza San Marco

Medici Chapels











