A coastal town with a pier, boats, and a hillside with buildings.

Luxury Hotels & Resorts in Pythagorio from AU$106

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Check availability on Pythagorio Luxury Hotels

Tonight
25 Sept - 26 Sept
Tomorrow
26 Sept - 27 Sept
This weekend
25 Sept - 27 Sept
Next weekend
2 Oct - 4 Oct

Our top choices for Pythagorio luxury hotels

A modern resort with a central pool, lounge areas, and mountain views.
A spa area with two massage tables, a stone floor, and a bamboo partition.
A beachside lounge area with outdoor seating, a large umbrella, and a view of the sea.
A bar area with a wooden counter and stools.

1. Casa Cook Samos

Casa Cook Samos
Samos
  • Beachfront luxury meets spa indulgence at Casa Cook Samos, where Mediterranean elegance awaits.
AU$357
includes taxes & fees
16 Oct - 17 Oct
Casa Cook Samos
A beach with rows of beige lounge chairs and umbrellas, a clear sky, and a calm sea with a distant mountain.
A beachside lounge with white umbrellas and beige lounge chairs, a wooden deck, and a view of the sea and a pier in the background.
A poolside table with a meal, a drink, and a view of a pool and mountains.
A modern kitchen with a central island, pendant lighting, and a tiled backsplash.

2. Doryssa Seaside Resort

Doryssa Seaside Resort
Samos
  • Relish beachfront luxury at this Samos seaside resort where warm staff, 2 outdoor pools, and a private beach create an indulgent escape.
AU$299
includes taxes & fees
25 Oct - 26 Oct
Doryssa Seaside Resort
A row of wooden beach umbrellas with white cushions on a sandy beach, overlooking the sea.
A beach with rows of sunbeds and thatched umbrellas, a clear blue sea, and mountains in the background.
A covered outdoor seating area with wooden flooring, white cushioned chairs, and tables.
A modern bedroom with a bed, bedside tables, a desk, and a view of the sea.

3. Proteas Blu Resort - Adults Only

Proteas Blu Resort - Adults Only
Samos
  • Private beachfront luxury meets seaside serenity at this adults-only Samos resort offering spa indulgences and ocean-view dining.
AU$268
includes taxes & fees
5 Oct - 6 Oct
Proteas Blu Resort - Adults Only
A person in a colorful swimsuit standing on a balcony overlooking the ocean.
A coastal residential area with multi-story buildings, a swimming pool, and a view of the sea and a mountain in the distance.
An indoor swimming pool with lounge chairs, a table, and a ceiling with wooden beams.
A beach with clear blue water, a sandy shore, and a few boats. There are buildings with colorful roofs in the background.

4. Hydrele Beach Hotel

Hydrele Beach Hotel
Samos
AU$178
includes taxes & fees
3 Oct - 4 Oct
Hydrele Beach Hotel
An outdoor cafe with tables, chairs, potted plants, and a tree with ripe oranges.
A modern living room with a sofa, wooden side tables, a round ottoman, and a dining area with chairs and a kitchen in the background.
A modern kitchen with dark cabinetry, a central island, and two chairs.
A modern interior with a central seating area, a kitchen in the background, and large windows.

5. Doryssa Theorem Hotel

Doryssa Theorem Hotel
Samos
AU$189
includes taxes & fees
5 Oct - 6 Oct
Doryssa Theorem Hotel
A pool area with lounge chairs and umbrellas, surrounded by stone walls and greenery.
A wooden deck with lounge chairs and a pool.
A boutique hotel entrance with a stone pathway, wooden gates, and potted plants.
A bedroom with a wooden wall, a hanging textured light fixture, and a bed with pillows.

6. Doryssa Boutique Hotel

Doryssa Boutique Hotel
Samos
AU$225
includes taxes & fees
1 Oct - 2 Oct
Doryssa Boutique Hotel
An infinity pool with lounge chairs and a view of a coastal town.
A modern multi-story building with a landscaped courtyard, featuring a mix of flat and sloped roofs, and a variety of plants and trees.
A bar area with stools, a counter, and bottles.
A modern interior with a dark wood reception desk, a sofa, a large abstract painting, and a potted plant.

7. Nirema Hotel & Spa Samos - MGallery Collection (opening Q3 2026)

Nirema Hotel & Spa Samos - MGallery Collection (opening Q3 2026)
Samos
AU$273
includes taxes & fees
23 Oct - 24 Oct
Nirema Hotel & Spa Samos - MGallery Collection (opening Q3 2026)
A wooden deck with lounge chairs and a thatched umbrella.
An outdoor seating area with modern furniture and a stone wall.
A hotel room with a bed, a large mirror, a TV, a bathroom with a large sink, and a view of a pool and building outside.
An outdoor dining area with wicker furniture, a bar with shelves of bottles, and a view of trees and mountains in the background.

8. Samian Mare Hotel Suites & Spa

Samian Mare Hotel Suites & Spa
Samos
AU$149
includes taxes & fees
27 Sept - 28 Sept
Samian Mare Hotel Suites & Spa
A wooden deck with lounge chairs and a thatched umbrella.
A restaurant with a view of the ocean, wooden tables and chairs, and a bar area with shelves of bottles and glasses.
A modern restaurant with wooden furniture and large windows offering a view of the sea.
A modern bathroom with two round sinks, a large mirror, and a view of the sea.

9. Erato by Samian Mare

Erato by Samian Mare
Samos
AU$141
includes taxes & fees
12 Oct - 13 Oct
Erato by Samian Mare
A coastal town with terraced houses, a dock with boats, and potted plants on a balcony.
A buffet with various food items and a glass partition.
A coastal town with buildings along the shoreline, a prominent hill in the background, and a clear view of the sea.
An aerial view of a coastal residential area with a swimming pool, multiple houses, and a road leading to the sea.

10. Arion Hotel

Arion Hotel
Samos
Arion Hotel
View all properties

Top Pythagorio Hotel Reviews

Doryssa Seaside Resort

Doryssa Seaside Resort

8/10 Good
"Very good, friendly place"
Zafer 3-night trip
Posted 1 month ago
Doryssa Seaside Resort

Frequently asked questions

Are you searching for the perfect hotel for your luxury trip to Pythagorio?
During your visit, you might want to enjoy the port which Pythagorio is known for.
What's the best luxury hotel in Pythagorio?
Casa Cook Samos is a luxury hotel with a beachfront restaurant and 2 bars, and it's a popular choice for Expedia travellers looking for an elegant place to stay. Proteas Blu Resort - Adults Only and Doryssa Seaside Resort are other upscale choices for your trip.
When can I expect good weather in Pythagorio?
Planning for the weather is an important factor for making your trip to Pythagorio a success, especially when you're splurging. The hottest months are usually August and July, with an average temperature of 25°C, while the coldest months are January and February, with an average of 13°C. Average annual precipitation for Pythagorio is 837 mm.
What's there to see and do in Pythagorio?
Experience Pythagorio with a stop at Samos Pythagorion Archaeological Museum, Pythagoreion and Glicorisa Beach. If you have spare time during your trip, you might want to make a stop at Folklore Museum of the Nikolaos Dimitriou Foundation of Samos and Tunnel of Eupalinos.

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