The best area to stay in Plzen is the Old Town, which is the historic heart of the city.The Old Town is centred around Republic Square (Náměstí Republiky) and is where you'll find most of Plzen's main attractions. It's very walkable, with cobblestone streets and historic buildings. Key landmarks include the St. Bartholomew's Cathedral with its towering spire, the Old Town Hall, and the Great Synagogue, one of the largest in Europe. Many local shops, cafes, and restaurants are dotted throughout this district.Couples will find the Old Town particularly appealing for a romantic or cultural getaway. The picturesque streets are lovely for strolls, and there are plenty of intimate restaurants and traditional pubs to discover. Its central location means you're never far from a landmark or a place to relax.For those interested in Plzen's brewing heritage, the area around the Pilsner Urquell Brewery, just a short walk east of the Old Town across the Radbuza River, is an excellent choice. This area provides easy access to brewery tours and the brewery's restaurant, offering a deep dive into the city's most famous export.