Default HTG hotel image

Penrose Hotels, St. Louis

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
23 Oct - 25 Oct
Next weekend
30 Oct - 1 Nov

Filter by

Property class

Guest rating

Selecting then applying a filter from this group will update the results on a new page

Our top choices for Penrose hotels

An outdoor patio area with tables and chairs, string lights, and umbrellas.

1. Hotel Indigo St Louis - Central West End by IHG

Hotel Indigo St Louis - Central West End by IHG
3.5 star property
Central West End, 4.3 km from Penrose
8.8 out of 10, Excellent, (1,002 reviews)
"Room was clean and staff were friendly!"
United States
Lydia
The price is AU$210
includes taxes & fees
22 Nov - 23 Nov
Hotel Indigo St Louis - Central West End by IHG
A modern living room with a fireplace, sofas, a coffee table, and a bookshelf.

2. AC Hotel St. Louis Central West End

AC Hotel St. Louis Central West End
4.0 star property
Central West End, 4.3 km from Penrose
9.0 out of 10, Wonderful, (858 reviews)
"Everything at this hotel was perfect. From the valet to the front desk to the breakfast were so friendly and nice. We will definitely stay here again. The location is also perfect"
United States
Janice
The price is AU$241
includes taxes & fees
21 Nov - 22 Nov
AC Hotel St. Louis Central West End
An outdoor patio area with seating, planters, and a grill.

3. Element by Marriott St. Louis Midtown

Element by Marriott St. Louis Midtown
3.0 star property
Midtown, 4.8 km from Penrose
8.8 out of 10, Excellent, (846 reviews)
"Would stay again!"
United States
Julie
The price is AU$220
includes taxes & fees
28 Oct - 29 Oct
Element by Marriott St. Louis Midtown
A modern hotel room with a large bed, a desk with a chair, a blue armchair, a sofa, a TV, and a large window offering a city view.

4. DoubleTree by Hilton St. Louis Forest Park

DoubleTree by Hilton St. Louis Forest Park
4.0 star property
Central West End, 4.8 km from Penrose
8.4 out of 10, Very good, (1,002 reviews)
"All was good"
United States
Loleta
The price is AU$243
includes taxes & fees
20 Nov - 21 Nov
DoubleTree by Hilton St. Louis Forest Park
A spacious indoor area with multiple dining tables and chairs, a fireplace, and a large artwork on the wall.

5. Hilton Garden Inn St. Louis Airport

Hilton Garden Inn St. Louis Airport
3.0 star property
8.6 km from Penrose
8.4 out of 10, Very good, (1,000 reviews)
"Breakfast has coupon system which is a tad bit inconvenient"
United States
Rashmi
The price is AU$182
includes taxes & fees
14 Nov - 15 Nov
Hilton Garden Inn St. Louis Airport
A modern building with a prominent blue sign, outdoor seating with a round table and chairs, and a view of the cityscape in the background.

6. Aloft by Marriott St Louis Central West End

Aloft by Marriott St Louis Central West End
3.0 star property
Central West End, 4.8 km from Penrose
8.6 out of 10, Excellent, (1,001 reviews)
"Very nice staff and helped us with all our needs and was close to the event we were going to and loved the pool table and pool they had there"
United States
Brittany
The price is AU$190
includes taxes & fees
25 Oct - 26 Oct
Aloft by Marriott St Louis Central West End
An outdoor seating area with a fire pit, cushioned benches, and a covered patio with string lights.

7. Home2 Suites by Hilton St. Louis/Forest Park

Home2 Suites by Hilton St. Louis/Forest Park
3.0 star property
The Grove, 5.5 km from Penrose
8.6 out of 10, Excellent, (1,002 reviews)
"Very clean room staff was awesome. Recommend."
United States
MARY
The price is AU$259
includes taxes & fees
25 Oct - 26 Oct
Home2 Suites by Hilton St. Louis/Forest Park
A rooftop terrace with outdoor seating, string lights, and a city skyline view.

8. Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
4.0 star property
4.4 km from Penrose
8.8 out of 10, Excellent, (1,167 reviews)
"Always our top pick to stay when in town for travel. Great people, Great vibes and a Great distance from alot of downtown hot spots ☺️"
United States
Skylee
The price is AU$174
includes taxes & fees
22 Nov - 23 Nov
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
Property amenity

9. Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station
3.0 star property
Downtown West, 5.8 km from Penrose
8.8 out of 10, Excellent, (2,258 reviews)
"Great location and loved the happy hour drinks and snacks"
United States
Larry
The price is AU$173
includes taxes & fees
22 Nov - 23 Nov
Pear Tree Inn St. Louis Near Union Station
The Clayton Plaza Hotel sign with a stone wall and plants in front.

10. Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay
3.5 star property
9.1 km from Penrose
9.0 out of 10, Wonderful, (3,501 reviews)
"Great location and place to stay"
United States
Sarah
The price is AU$154
includes taxes & fees
1 Nov - 2 Nov
Clayton Plaza Hotel & Extended Stay
A hot tub with a wooden deck, surrounded by a bamboo fence, and string lights.

11. The West End

The West End
2.0 star property
Central West End, 4.2 km from Penrose
8.6 out of 10, Excellent, (697 reviews)
"Excellent value, location. I'd stay here again."
United States
Trevor
The price is AU$186
includes taxes & fees
1 Nov - 2 Nov
The West End
A modern lobby with a staircase, seating area, and wall-mounted artwork.

12. Moonrise Hotel

Moonrise Hotel
4.0 star property
5.8 km from Penrose
9.0 out of 10, Wonderful, (2,049 reviews)
"Such a cute place to stay, and convenient to a music venue and restaurants."
United States
Jessie
The price is AU$273
includes taxes & fees
27 Oct - 28 Oct
Moonrise Hotel
An indoor pool area with a hot tub, seating, and a stone wall.

13. Drury Plaza Hotel St. Louis Union Station

Drury Plaza Hotel St. Louis Union Station
3.0 star property
Downtown West, 6.1 km from Penrose
9.4 out of 10, Exceptional, (1,599 reviews)
"Amazing food and friendly staff"
United States
Andrea
The price is AU$191
includes taxes & fees
1 Nov - 2 Nov
Drury Plaza Hotel St. Louis Union Station
An indoor swimming pool with lounge chairs and a pool table, surrounded by large windows.

14. Hampton Inn & Suites St. Louis at Forest Park

Hampton Inn & Suites St. Louis at Forest Park
3.5 star property
Dogtown, 6.5 km from Penrose
9.4 out of 10, Exceptional, (1,002 reviews)
"Great location clean room"
United States
Melissa
The price is AU$219
includes taxes & fees
1 Nov - 2 Nov
Hampton Inn & Suites St. Louis at Forest Park
A hotel with a swimming pool, lounge chairs, and a courtyard with palm trees.

15. The Royal Sonesta Chase Park Plaza St. Louis

The Royal Sonesta Chase Park Plaza St. Louis
4.5 star property
Central West End, 4.4 km from Penrose
9.2 out of 10, Wonderful, (1,002 reviews)
"The Sonesta is a lovely hotel with a beautiful pool. Our stay was a relaxing getaway and pleasant in every way."
United States
Kristina
The price is AU$267
includes taxes & fees
22 Nov - 23 Nov
The Royal Sonesta Chase Park Plaza St. Louis
A lobby with a sofa, two armchairs, a coffee table, and a staircase.

16. Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch
4.0 star property
Downtown St. Louis, 7.3 km from Penrose
8.6 out of 10, Excellent, (4,364 reviews)
"Great stay"
United States
Johnny
The price is AU$225
includes taxes & fees
30 Oct - 31 Oct
Hyatt Regency St. Louis at The Arch
A Comfort Inn & Suites hotel with a modern design, featuring a covered entrance and a brick facade.

17. Comfort Inn & Suites Saint Louis Lafayette Square

Comfort Inn & Suites Saint Louis Lafayette Square
2.5 star property
The Gate, 7.1 km from Penrose
8.2 out of 10, Very good, (423 reviews)
"Great breakfeast and the room was clean. Also lot of room to park!"
United States
greg
The price is AU$182
includes taxes & fees
23 Nov - 24 Nov
Comfort Inn & Suites Saint Louis Lafayette Square
A modern outdoor seating area with a fire pit, surrounded by wicker furniture and a landscaped garden.

18. Courtyard by Marriott St. Louis Downtown West

Courtyard by Marriott St. Louis Downtown West
3.0 star property
Downtown West, 5.7 km from Penrose
8.6 out of 10, Excellent, (1,002 reviews)
"We had a wonderful stay"
Canada
nadia
The price is AU$193
includes taxes & fees
15 Nov - 16 Nov
Courtyard by Marriott St. Louis Downtown West
A multi-story building with a classic architectural style, featuring numerous windows and a brick facade.

19. Courtyard by Marriott St. Louis Downtown/Convention Center

Courtyard by Marriott St. Louis Downtown/Convention Center
3.0 star property
Downtown St. Louis, 6.6 km from Penrose
9.0 out of 10, Wonderful, (1,013 reviews)
"Clean room nice wonderful staff"
United States
CESAR
The price is AU$178
includes taxes & fees
15 Nov - 16 Nov
Courtyard by Marriott St. Louis Downtown/Convention Center
An outdoor seating area with multiple tables and chairs, large umbrellas, and a built-in fire feature against a stone wall.

20. Fairfield Inn & Suites by Marriott St. Louis Downtown

Fairfield Inn & Suites by Marriott St. Louis Downtown
3.0 star property
Downtown West, 5.8 km from Penrose
9.2 out of 10, Wonderful, (1,000 reviews)
"Nice stay!"
United States
Brooke
The price is AU$197
includes taxes & fees
1 Nov - 2 Nov
Fairfield Inn & Suites by Marriott St. Louis Downtown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare top hotels in Penrose

An outdoor patio area with tables and chairs, string lights, and umbrellas.

Hotel Indigo St Louis - Central West End by IHG

3.5 star property
Central West End, 4.3 km from Penrose
View
A modern living room with a fireplace, sofas, a coffee table, and a bookshelf.

AC Hotel St. Louis Central West End

4.0 star property
Central West End, 4.3 km from Penrose
View
An outdoor patio area with seating, planters, and a grill.

Element by Marriott St. Louis Midtown

3.0 star property
Midtown, 4.8 km from Penrose
View
A modern hotel room with a large bed, a desk with a chair, a blue armchair, a sofa, a TV, and a large window offering a city view.

DoubleTree by Hilton St. Louis Forest Park

4.0 star property
Central West End, 4.8 km from Penrose
View
A spacious indoor area with multiple dining tables and chairs, a fireplace, and a large artwork on the wall.

Hilton Garden Inn St. Louis Airport

3.0 star property
8.6 km from Penrose
View
8.8
Excellent
1,002 reviews
9.0
Wonderful
858 reviews
8.8
Excellent
846 reviews
8.4
Very good
1,002 reviews
8.4
Very good
1,000 reviews
The price is AU$210
includes taxes & fees
22 Nov - 23 Nov
The price is AU$241
includes taxes & fees
21 Nov - 22 Nov
The price is AU$220
includes taxes & fees
28 Oct - 29 Oct
The price is AU$243
includes taxes & fees
20 Nov - 21 Nov
The price is AU$182
includes taxes & fees
14 Nov - 15 Nov
  • No Breakfast included
  • No Pool
  • No Spa
  • Yes, Pet-friendly
  • Yes, WiFi included
  • Yes, Parking
  • No Breakfast included
  • No Pool
  • No Spa
  • No Pet-friendly
  • Yes, WiFi included
  • Yes, Parking
  • Yes, Breakfast included
  • Yes, Pool
  • No Spa
  • Yes, Pet-friendly
  • Yes, WiFi included
  • Yes, Parking
  • No Breakfast included
  • No Pool
  • No Spa
  • Yes, Pet-friendly
  • Yes, WiFi included
  • Yes, Parking
  • No Breakfast included
  • Yes, Pool
  • No Spa
  • Yes, Pet-friendly
  • Yes, WiFi included
  • Yes, Parking

Hotels recommended for families in Penrose

An outdoor patio area with tables and chairs, string lights, and umbrellas.

Hotel Indigo St Louis - Central West End by IHG

Hotel Indigo St Louis - Central West End by IHG
3.5 star property
Central West End
8.8 out of 10, Excellent, (1,002)
The price is AU$210
includes taxes & fees
22 Nov - 23 Nov
Hotel Indigo St Louis - Central West End by IHG

Our guide on where to stay in Penrose

Find the best Penrose areas for the activities you enjoy most.
The Gateway Arch in St. Louis, Missouri, with a well-maintained lawn and trees in the foreground.

Downtown St. Louis

Gourmet restaurants beloved sports teams and top sights from Old Courthouse to Gateway Arch National Park – discover Downtown St. Louis, a destination also famous for its historic sites.

A gazebo by a calm pond with autumn foliage and clear skies.

Clayton

Take time in Clayton to visit attractions like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. You might also appreciate the abundant dining options, and you can hop on the metro at Clayton Station to see more of the city.

A wooden bridge with metal trusses, surrounded by trees.

St. Charles Historic District

St. Charles Historic District is known for its ample dining options, and you can make a stop by Historic Main Street and Missouri River while in the area.

A historic building with a green dome and adjacent modern high-rise buildings.

Central West End

Enjoy this relaxed area, the ultimate destination for a lazy afternoon. Browse unique stores, admire artworks and sip coffee at sidewalk tables shaded by trees.

A lake with a curved shoreline, a parking lot, and a forested area with autumn foliage.

Creve Coeur

Travellers come to Creve Coeur for its abundant dining options, and you can see top attractions like Creve Coeur Golf Club and Skip Viragh Center for the Arts while you're in town.

Top Penrose Hotel Reviews

Recent Reviews in Penrose

21C Museum Hotel St Louis

21C Museum Hotel St Louis

8/10 Good
"The location was great for the concert we were attending. The staff was great from the Valet, Front Desk, and everyone at the bar etc.. Room was upscale and had everything needed. Boutique hotel with Great Service. The food was good but not great, but to be fair we were ordering everything in order to be quick to make it to our concert. If we had more time it could have been better."
robert 1-night trip
Posted 4 hours ago
21C Museum Hotel St Louis

Frequently asked questions

What's it like in Penrose?
Travellers are sure to enjoy a stay in St. Louis's Penrose neighbourhood. Consider a visit to Julia Davis Branch Library as part of your Penrose travel plans.
If I need to cancel my hotel reservation in Penrose, will I receive a refund?
Yes! The majority of room reservations are refundable if you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of check in. If your reservation is non-refundable, you might still have the option to cancel and receive a refund within 24 hours of your booking. Put your dates in and click on "Search", then filter by "fully refundable" to get top deals in Penrose.
What is there to do around this St. Louis neighbourhood?
Julia Davis Branch Library is an attraction you might want to check out while you're in Penrose. Shelley House and Bellefontaine Cemetery are also worth a visit when you're out sightseeing in St. Louis.