Search Pamplico hotels

Start date: Check-in selected.
To Date
End date: Check-out
  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Next weekend
In two weeks

Filter by

Guest rating
Guest rating
Star rating

Top hotels and accommodation in Pamplico

Park Inn by Radisson Florence, SC

2.5 star property
Florence
9.0 out of 10, Wonderful, (2192)
"the room was nice and clean"
United States
Tina
Travelling with family
The price is AU$159
includes taxes & fees
14 Dec - 15 Dec
Park Inn by Radisson Florence, SC

Holiday Inn Express & Suites Latta by IHG

2.5 star property
Latta
9.4 out of 10, Exceptional, (529)
"This hotel is in great proximity"
United States
Rammise
Travelling for leisure
The price is AU$195
includes taxes & fees
4 Jan - 5 Jan 2026
Holiday Inn Express & Suites Latta by IHG

Comfort Inn & Suites Florence Center Area

2.5 star property
Florence
9.2 out of 10, Wonderful, (1158)
"parking lot is well lit and safe"
United States
Jill
Travelling for leisure
The price is AU$169
includes taxes & fees
4 Jan - 5 Jan 2026
Comfort Inn & Suites Florence Center Area

Hampton Inn & Suites Florence-North-I-95

2.5 star property
Florence
9.0 out of 10, Wonderful, (809)
"Excellent service, clean comfortable room, updated and spacious bathroom."
United States
Grace
Travelling with family
The price is AU$180
includes taxes & fees
6 Jan - 7 Jan 2026
Hampton Inn & Suites Florence-North-I-95

Hyatt Place Florence Downtown

3.0 star property
Florence
8.8 out of 10, Excellent, (1002)
"The hotel has a fully stocked premium bar, variety of food options in walking distance, and very clean."
United States
Tanquir
Travelling for leisure
The price is AU$169
includes taxes & fees
15 Dec - 16 Dec
Hyatt Place Florence Downtown

Tru by Hilton Florence I-95

2.5 star property
Florence
8.4 out of 10, Very good, (1001)
"Very clean comfortable and easy check in."
United States
Shaun
Travelling for leisure
The price is AU$159
includes taxes & fees
29 Dec - 30 Dec
Tru by Hilton Florence I-95

Fairfield Inn & Suites by Marriott Florence I-20

2.5 star property
Florence
9.0 out of 10, Wonderful, (547)
"The room was super clean."
United States
Madhusudan
Travelling with partner
The price is AU$181
includes taxes & fees
14 Dec - 15 Dec
Fairfield Inn & Suites by Marriott Florence I-20

Best Western Executive Inn

2.5 star property
Latta
8.2 out of 10, Very good, (930)
"I also felt safe in the area and it is close to the highway"
United States
Mersades
Travelling with family
The price is AU$160
includes taxes & fees
16 Dec - 17 Dec
Best Western Executive Inn

Homewood Suites by Hilton Florence

3.0 star property
Florence
8.4 out of 10, Very good, (657)
"Loved the clean rooms and amenities."
United States
Jeff
The price is AU$167
includes taxes & fees
4 Jan - 5 Jan 2026
Homewood Suites by Hilton Florence

Howard Johnson by Wyndham Florence

2.0 star property
Florence
8.8 out of 10, Excellent, (2476)
"the room was really clean"
United States
Jane
Travelling for leisure
The price is AU$105
includes taxes & fees
9 Dec - 10 Dec
Howard Johnson by Wyndham Florence

Home2 Suites by Hilton Florence, SC

3.0 star property
Florence
8.2 out of 10, Very good, (1002)
"Breakfast and the nearby restaurants and shopping is amazing"
United States
Janai
Travelling for leisure
The price is AU$174
includes taxes & fees
14 Dec - 15 Dec
Home2 Suites by Hilton Florence, SC

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

2.5 star property
Florence
9.2 out of 10, Wonderful, (1002)
"Comfortable beds with large bathroom"
United States
Hong
The price is AU$186
includes taxes & fees
14 Dec - 15 Dec
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

Spark by Hilton Florence North I-95, SC

2.5 star property
Florence
7.8 out of 10, Good, (21)
"Rooms were nice and clean"
United States
ANNETTE
Travelling for leisure
The price is AU$160
includes taxes & fees
16 Dec - 17 Dec
Spark by Hilton Florence North I-95, SC

Hampton Inn & Suites Florence Center

2.5 star property
Florence
9.0 out of 10, Wonderful, (812)
"Very convenient off the highway, modest but nice and clean hotel"
United States
Maria
Travelling with family
The price is AU$161
includes taxes & fees
21 Dec - 22 Dec
Hampton Inn & Suites Florence Center

Bella's Boutique Hotel

2.0 star property
Hemingway
6.0 out of 10, (12)
"Quaint and cozy, convenient for visiting family. The staff and owner were very welcoming and generous. "
United States
James
The price is AU$149
includes taxes & fees
18 Dec - 19 Dec
Bella's Boutique Hotel

Comfort Suites Florence I-95

2.5 star property
Florence
8.4 out of 10, Very good, (1002)
"Very nice and clean room."
United States
Marilyn
Travelling for leisure
The price is AU$178
includes taxes & fees
8 Dec - 9 Dec
Comfort Suites Florence I-95

La Quinta Inn & Suites by Wyndham Florence

3.0 star property
Florence
8.0 out of 10, Very good, (1675)
"the shower pressure is great"
United States
Wendy
Travelling with family
The price is AU$164
includes taxes & fees
7 Dec - 8 Dec
La Quinta Inn & Suites by Wyndham Florence

Best Western Inn

2.5 star property
Florence
7.6 out of 10, Good, (1000)
"The room was quiet and safe"
United States
Jacob
Travelling with small children
The price is AU$150
includes taxes & fees
14 Dec - 15 Dec
Best Western Inn

Quality Inn & Suites Florence Civic Center

2.5 star property
Florence
7.8 out of 10, Good, (1253)
"The hotel is clean and freshly renovated"
United States
William
Travelling for business
The price is AU$129
includes taxes & fees
5 Jan - 6 Jan 2026
Quality Inn & Suites Florence Civic Center

Staybridge Suites Florence - Civic Center by IHG

3.0 star property
Florence
9.4 out of 10, Exceptional, (922)
"Very nice, yo to date, clean great safe location."
United States
Michael
The price is AU$228
includes taxes & fees
14 Dec - 15 Dec
Staybridge Suites Florence - Civic Center by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Top Pamplico Hotel Reviews

Recent Reviews in Pamplico

More cheap accommodation in Pamplico

Frequently asked questions

What's the best place for a stay in Pamplico?
Located 21 mi (33.8 km) from the heart of Pamplico, Howard Johnson by Wyndham Florence is a top choice for your stay, based on our traveller data. Two other choices for your visit to the area are Park Inn by Radisson Florence, SC and Comfort Inn & Suites Florence Center Area. See all available top hotels, or vacation rentals in Pamplico.
What are some of the best holiday rentals that Pamplico has to offer?
Take a rest in Florence .Ideal for i95 traveler and Florence Center and Buc-ee's: This holiday home rental outside of Pamplico offers a fireplace, a patio and air conditioning to help you feel perfectly comfortable in your new surroundings. It has 3 bedrooms, as well as a kitchen with a dishwasher, a fridge and a stovetop, so that you can cook with friends or family. Make the most of garden in this rental home to help you unwind. See all vacation rentals in Pamplico.
If I need to cancel my hotel reservation in Pamplico, will I receive a refund?
Yes, the majority of hotel bookings are refundable provided that you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you booked a non-refundable reservation, you might be able to cancel it and be given a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Pamplico.
What is staying in Pamplico like?
Visitors will definitely enjoy all that Pamplico has to offer. There are 136 hotels and other accommodation options in the surrounding area. Find out more about Pamplico.
What are the top places to visit in Pamplico?
Places to visit in the wider area include Eastern Carolina Agricultural Fairgrounds, Florence National Cemetery and Florence Museum. You'll also find Lynches River State Park and Lions Park in the area. Take a look at what more there is to see and do in Expedia's Pamplico guide.
What's the seasonal weather in Pamplico?
The hottest months are usually July and August, with an average temperature of 26°C, while the coldest months are January and February, with an average of 10°C. Average annual precipitation for Pamplico is 1351 mm.

Explore a world of travel with Expedia