Default HTG hotel image

Search Pamplico hotels

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
24 July - 26 July
Next weekend
31 July - 2 Aug

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Pamplico hotels

Exterior

1. The Inn at the Crossroads

The Inn at the Crossroads
2.0 star property
Lake City
9.4 out of 10, Exceptional, (918 reviews)
"Very professional staff made the visit pleasant as always."
United States
Bryant Keith
The price is AU$179
includes taxes & fees
9 Aug - 10 Aug
The Inn at the Crossroads
Lobby

2. Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence
2.0 star property
Florence
8.6 out of 10, Excellent, (2,683 reviews)
"Amazing stay!"
United States
Miriam
The price is AU$101
includes taxes & fees
23 July - 24 July
Howard Johnson by Wyndham Florence
Exterior

3. Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG

Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG
2.5 star property
Florence
8.6 out of 10, Excellent, (1,003 reviews)
"Great stay. Clean room, great breakfast"
United States
Tim
The price is AU$190
includes taxes & fees
17 Aug - 18 Aug
Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG
Lobby

4. Quality Inn & Suites Lake City

Quality Inn & Suites Lake City
2.5 star property
Lake City
7.2 out of 10, Good, (187 reviews)
"Hotel was just ok. It was clean, but minimal and basic"
United States
patrick
The price is AU$182
includes taxes & fees
19 Aug - 20 Aug
Quality Inn & Suites Lake City
Terrace/patio

5. Hyatt Place Florence Downtown

Hyatt Place Florence Downtown
3.0 star property
Florence
9.0 out of 10, Wonderful, (1,000 reviews)
"Room was clean, location was perfect and the staff was extremely helpful, and kind"
United States
Jennifer A
The price is AU$182
includes taxes & fees
3 Aug - 4 Aug
Hyatt Place Florence Downtown
Lobby

6. Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area
2.5 star property
Florence
9.0 out of 10, Wonderful, (1,333 reviews)
"The staff made us feel like family!"
United States
Monica
The price is AU$177
includes taxes & fees
2 Aug - 3 Aug
Comfort Inn & Suites Florence Center Area
Bar (on property)

7. Hotel Florence, Tapestry Collection by Hilton

Hotel Florence, Tapestry Collection by Hilton
3.0 star property
Florence
8.8 out of 10, Excellent, (646 reviews)
"This is a beautiful place. We look forward to staying again"
United States
John
The price is AU$222
includes taxes & fees
2 Aug - 3 Aug
Hotel Florence, Tapestry Collection by Hilton
Lobby sitting area

8. Spark by Hilton Florence North I-95, SC

Spark by Hilton Florence North I-95, SC
2.5 star property
Florence
8.4 out of 10, Very good, (225 reviews)
"Staff very friendly & accommodating for my family!"
United States
Samantha
The price is AU$149
includes taxes & fees
3 Aug - 4 Aug
Spark by Hilton Florence North I-95, SC
Suite, 1 King Bed with Sofa bed, Non Smoking

9. Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center
2.5 star property
Florence
8.6 out of 10, Excellent, (269 reviews)
"Clean room and staff was great"
United States
John A
The price is AU$143
includes taxes & fees
26 July - 27 July
Quality Inn & Suites Florence Civic Center
Lobby

10. Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC
2.5 star property
Florence
9.0 out of 10, Wonderful, (2,348 reviews)
"Staff very kind and the breakfast was excellent!"
United States
Kimberly
The price is AU$128
includes taxes & fees
16 Aug - 17 Aug
Park Inn by Radisson Florence, SC
Lobby

11. Comfort Suites Florence I-95

Comfort Suites Florence I-95
2.5 star property
Florence
8.2 out of 10, Very good, (1,000 reviews)
"The breakfast was great and the rooms were super comfortable "
United States
Jessica
The price is AU$152
includes taxes & fees
16 Aug - 17 Aug
Comfort Suites Florence I-95
Restaurant

12. Hampton Inn & Suites Florence Center

Hampton Inn & Suites Florence Center
2.5 star property
Florence
9.0 out of 10, Wonderful, (932 reviews)
"Great place to stay"
United States
Harry
The price is AU$176
includes taxes & fees
16 Aug - 17 Aug
Hampton Inn & Suites Florence Center
Indoor pool

13. Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
2.5 star property
Florence
9.2 out of 10, Wonderful, (1,000 reviews)
"This will be my hotel of choice, when visiting Florence SC."
United States
Hazel
The price is AU$166
includes taxes & fees
22 Aug - 23 Aug
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
View from property

14. Fairfield Inn & Suites by Marriott Florence I-20

Fairfield Inn & Suites by Marriott Florence I-20
3.0 star property
Florence
9.0 out of 10, Wonderful, (650 reviews)
"Everything from check in to check out was great. The location was amazing to. The Florence Center"
United States
Brian
The price is AU$203
includes taxes & fees
27 July - 28 July
Fairfield Inn & Suites by Marriott Florence I-20
Lobby

15. Days Inn by Wyndham Lake City

Days Inn by Wyndham Lake City
2.0 star property
Lake City
6.4 out of 10, (260 reviews)
"the staff was wonderfully accommodating."
United States
Gian
The price is AU$165
includes taxes & fees
9 Aug - 10 Aug
Days Inn by Wyndham Lake City
Studio, Multiple Beds

16. TownePlace Suites by Marriott Florence

TownePlace Suites by Marriott Florence
3.0 star property
Florence
9.0 out of 10, Wonderful, (859 reviews)
"Clean room, friendly staff and delicious breakfast."
United States
Tameka
The price is AU$182
includes taxes & fees
27 July - 28 July
TownePlace Suites by Marriott Florence
Front of property

17. Best Western Inn

Best Western Inn
2.5 star property
Florence
7.8 out of 10, Good, (1,003 reviews)
"Nice place to stop and rest with a few restaurants and gas stations near by."
United States
Michael
The price is AU$142
includes taxes & fees
23 July - 24 July
Best Western Inn
Exterior

18. Rodeway Inn Florence Downtown

Rodeway Inn Florence Downtown
2.0 star property
Florence
6.0 out of 10, (6 reviews)
"Good"
United States
Joshua
The price is AU$70
includes taxes & fees
20 Aug - 21 Aug
Rodeway Inn Florence Downtown
Exterior

19. Quality Inn Mullins - Marion

Quality Inn Mullins - Marion
2.5 star property
Marion
7.6 out of 10, Good, (411 reviews)
"McCall was fantastic! Very helpful!"
United States
Daniel
The price is AU$132
includes taxes & fees
17 Aug - 18 Aug
Quality Inn Mullins - Marion
Terrace/patio

20. Tru by Hilton Florence I-95

Tru by Hilton Florence I-95
2.5 star property
Florence
8.6 out of 10, Excellent, (1,000 reviews)
"Great amenities the lobby was huge and really nice."
United States
Elizabeth
The price is AU$162
includes taxes & fees
2 Aug - 3 Aug
Tru by Hilton Florence I-95
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Pamplico Hotel Reviews

Recent Reviews in Pamplico

TownePlace Suites by Marriott Florence

TownePlace Suites by Marriott Florence

10/10 Excellent
"Great place for an overnight stay on our road trip. Room was clean and comfortable for our family of 6."
Jillian 1-night trip
Posted 2 hours ago
TownePlace Suites by Marriott Florence

More cheap accommodation in Pamplico

Days Inn by Wyndham Florence/I-95 North

Days Inn by Wyndham Florence/I-95 North

2111 West Lucas St/I-95 Florence SC
The price is AU$83 per night from 9 Aug to 10 Aug
AU$83
9 Aug - 10 Aug
includes taxes & fees

Frequently asked questions

What is the best area to stay in Pamplico?
The best area to stay in Pamplico is within the town centre itself, particularly around Main Street.

This area is the heart of Pamplico, offering the most convenience for visitors. Main Street is where you'll find the majority of local businesses, including small shops and eateries, and it's easily navigable on foot. The town's historic charm is evident in the architecture of the older buildings lining the street.

For solo travellers or couples, staying within the town centre provides easy access to local life and amenities. You'll be able to stroll to local cafes for breakfast or explore the few boutique shops without needing a car.
When is the best time to go to Pamplico?
The best time to visit Pamplico, South Carolina, is during the spring (April to May) and autumn (September to October) months.

These seasons offer pleasant weather conditions, with comfortable temperatures and lower humidity compared to the summer. This makes it ideal for enjoying outdoor activities and exploring the local area without the intense heat.

For those interested in local agricultural events and the natural beauty of the Pee Dee Region, these periods often coincide with local festivals and the blooming or changing colours of the landscape.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if cancelled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Pamplico.
How can I save on a hotel booking in Pamplico with Expedia?
One Key™—Expedia's free travel rewards program—gives you instant access to discounts with Member Prices on Pamplico hotels. Plus, you'll earn OneKeyCash™* on eligible bookings to use on future trips. Booking an Expedia hotel and flight package is another great way to save, where bundling can result in significant savings. *Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
How much is the nightly rate for a hotel in Pamplico?
Prices for hotels in Pamplico often vary, but you can find a great deal from AU$70 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for our cheapest rates.

Explore a world of travel with Expedia